Click here to switch to the map view.

The map label for this gene is merP [H]

Identifier: 187928868

GI number: 187928868

Start: 1881621

End: 1881893

Strand: Direct

Name: merP [H]

Synonym: Rpic_1785

Alternate gene names: 187928868

Gene position: 1881621-1881893 (Clockwise)

Preceding gene: 187928867

Following gene: 187928869

Centisome position: 47.73

GC content: 60.07

Gene sequence:

>273_bases
ATGAAGAAGCTATTTGCCGCCCTCGCTCTTGCCGCCGTTGCTCCCGCATGGGCCGCCATGCAAACCGTCACGCTGTCCGT
GCCAGGCATGACTTGCGAAACCTGCCCGATCACGGTCAAGCATGCGCTCTCCAAAGTCGACGGCGTGAGCAAGACCGAGG
TGAGCTTCGAAAAGCGTCAGGCCGTCGTCACCTTCGATGATGCCAAGACCAGCGTGCAGAAACTGATCAAGGCAACCGAG
GACGCGGGCTACCCATCCAGCGTCAAGCACTGA

Upstream 100 bases:

>100_bases
GCCACCTACAAGGTCATTTTCTGGGTCGTCGCCCTGCTGGTTTTGGTTGCACTCGGATTTCCCTACGTGATGCCATTTTT
CTATTGATCAGGAGTTCGTC

Downstream 100 bases:

>100_bases
GTCCCTGGGCGAACACGGGAGCGAAATCATGGGCTGGATTGCGCGCGTGACCAACAAGGCAGGGGCGCTTGGCAGCATCG
TCTCGGCGATGGGGTGCGCG

Product: mercuric transport protein periplasmic component

Products: ADP; Orthophosphate. [C]

Alternate protein names: Mercury scavenger protein; Periplasmic mercury ion-binding protein [H]

Number of amino acids: Translated: 90; Mature: 90

Protein sequence:

>90_residues
MKKLFAALALAAVAPAWAAMQTVTLSVPGMTCETCPITVKHALSKVDGVSKTEVSFEKRQAVVTFDDAKTSVQKLIKATE
DAGYPSSVKH

Sequences:

>Translated_90_residues
MKKLFAALALAAVAPAWAAMQTVTLSVPGMTCETCPITVKHALSKVDGVSKTEVSFEKRQAVVTFDDAKTSVQKLIKATE
DAGYPSSVKH
>Mature_90_residues
MKKLFAALALAAVAPAWAAMQTVTLSVPGMTCETCPITVKHALSKVDGVSKTEVSFEKRQAVVTFDDAKTSVQKLIKATE
DAGYPSSVKH

Specific function: Mercury scavenger that specifically binds to one mercury ion and which passes it to the mercuric reductase (merA) via the merT protein [H]

COG id: COG2608

COG function: function code P; Copper chaperone

Gene ontology:

Cell location: Periplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HMA domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001757
- InterPro:   IPR017969
- InterPro:   IPR006121
- InterPro:   IPR001802
- InterPro:   IPR011795 [H]

Pfam domain/function: PF00403 HMA [H]

EC number: 3.6.3.4 [C]

Molecular weight: Translated: 9552; Mature: 9552

Theoretical pI: Translated: 9.30; Mature: 9.30

Prosite motif: PS01047 HMA_1 ; PS50846 HMA_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKLFAALALAAVAPAWAAMQTVTLSVPGMTCETCPITVKHALSKVDGVSKTEVSFEKRQ
CHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCCCCCHHHHHHHHHCCCCCCHHHHHHCE
AVVTFDDAKTSVQKLIKATEDAGYPSSVKH
EEEEECCHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MKKLFAALALAAVAPAWAAMQTVTLSVPGMTCETCPITVKHALSKVDGVSKTEVSFEKRQ
CHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCCCCCHHHHHHHHHCCCCCCHHHHHHCE
AVVTFDDAKTSVQKLIKATEDAGYPSSVKH
EEEEECCHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Cu [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; H2O [C]

Specific reaction: ATP + H2O = ADP + Orthophosphate. [C]

General reaction: Phosphorous acid anhydride hydrolysis [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8302940 [H]