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The map label for this gene is xerC [H]

Identifier: 187928816

GI number: 187928816

Start: 1828193

End: 1829386

Strand: Reverse

Name: xerC [H]

Synonym: Rpic_1733

Alternate gene names: 187928816

Gene position: 1829386-1828193 (Counterclockwise)

Preceding gene: 187928817

Following gene: 187928813

Centisome position: 46.4

GC content: 67.92

Gene sequence:

>1194_bases
ATGACCCATCCCGTTCCATCGTTCAACGGTCCCGCGGTGGCCATCGAGCAGTTGCGCATCCCGCCAGCGCTCTCGGGCCT
TCACGGCGCCAACCGCGCACGCGAAGCGAGCCGCCAAATCACGGCGGATGACGACCTGGCCGCCGTGGCTGCGTGGCTCG
CCCGCTATGCCGGCGTGCCCGGCACGGTCGCCACCTACCGCAAGGAAGCCGAACGCCTGATACTGTGGGCGATTCTCCAG
CACGGCAAGCCGCTGTCTTCACTCACCCACGAGGACCTGCTGCTCTACGAGCGCTTCCTGGCCGACCCGCAGCCAGCTTG
GCGTTGGGTGATGGCCTCACGCAAGAAGCTGGCGAGAAGCTCGCCCGACTGGCGCCCCTTCGCCGGTCCACTGTCGCCCA
CGAGCGTGCGGCATGCGATGACGATCCTCAACGCGCTCTTCGCCTGGCTGGTGCAAGCCGGATACCTCGCCGGGAATCCG
CTCTCGCTCGCGCGCCGTCGCAGCGCCAAGACAGCCCCGCGCGTGACGCGCTACCTCACGCATGCGCATTGGGACATCGT
CAAAGCCACGATCGAAACCCTGCCCGTCGCGACGGAACGCGACCGGCTGCACGCGGCCCGTTGCCGGTGGTTGTTCTCCG
TGCTGTATTTGGCCGGCCTGCGCTTAGCGGAAATCGCCTCCACGCGCATGGGCGCCGTGTTCTCTCGCCGGGACGCGGCG
GGCGTCGAGCGCTGGTGGATCGAGGTGCACGGCAAAGGCGGCAAGACGCGCCTGGTGCCCGCCACCGATGAACTGATCGC
GGAGCTGGCGCGCTATCGGCGCATCTGCGGCCTGCCGCCGTCACCGCAGATCGGCGAAACACGCCCTTTGCTGCTGCCCG
TGATCGGCCCGGAAAAGCCGTTATCGCGCGCGGCGATTCACCTGATCGTCAAGGAGGTGTTCAAGCTCGCGGCCGACCGC
GTGCGTGCACAGGGTCCCGAGTTTGGCGCGCAGGCTGACGTGCTCGCCAGCGCATCGTCCCACTGGCTGCGCCACACGGC
CGGCTCGCACATGTCCGACCAACAGGTGGACCTGCGCTTCGTGCGTGACAACTTCGGCCATGCGTCGCTCGCCACGACGA
GTGTCTACCTCCACGCGGAAGATGACGCACGCCACCAGGCAACGCAAGCCAGCCACCGGCTTGGCTGGAACTGA

Upstream 100 bases:

>100_bases
CCCGATGTCATCCCACCCACCGCCTTCGTCGACAGCGACGAAGACTGGCCGGACTTCGAGTGGTGAAACGCCCGCACGCT
AGGACGGCGGCCCTGCATCG

Downstream 100 bases:

>100_bases
GCGTACCCAATTCTCGATGGCATGCTCCACGCGCGGCGGCTGCCGGCATCACCCACGAAAACGGGCAAATCGCCATGGCA
GCCAGCGCATCGAAGGCGCC

Product: integrase family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 397; Mature: 396

Protein sequence:

>397_residues
MTHPVPSFNGPAVAIEQLRIPPALSGLHGANRAREASRQITADDDLAAVAAWLARYAGVPGTVATYRKEAERLILWAILQ
HGKPLSSLTHEDLLLYERFLADPQPAWRWVMASRKKLARSSPDWRPFAGPLSPTSVRHAMTILNALFAWLVQAGYLAGNP
LSLARRRSAKTAPRVTRYLTHAHWDIVKATIETLPVATERDRLHAARCRWLFSVLYLAGLRLAEIASTRMGAVFSRRDAA
GVERWWIEVHGKGGKTRLVPATDELIAELARYRRICGLPPSPQIGETRPLLLPVIGPEKPLSRAAIHLIVKEVFKLAADR
VRAQGPEFGAQADVLASASSHWLRHTAGSHMSDQQVDLRFVRDNFGHASLATTSVYLHAEDDARHQATQASHRLGWN

Sequences:

>Translated_397_residues
MTHPVPSFNGPAVAIEQLRIPPALSGLHGANRAREASRQITADDDLAAVAAWLARYAGVPGTVATYRKEAERLILWAILQ
HGKPLSSLTHEDLLLYERFLADPQPAWRWVMASRKKLARSSPDWRPFAGPLSPTSVRHAMTILNALFAWLVQAGYLAGNP
LSLARRRSAKTAPRVTRYLTHAHWDIVKATIETLPVATERDRLHAARCRWLFSVLYLAGLRLAEIASTRMGAVFSRRDAA
GVERWWIEVHGKGGKTRLVPATDELIAELARYRRICGLPPSPQIGETRPLLLPVIGPEKPLSRAAIHLIVKEVFKLAADR
VRAQGPEFGAQADVLASASSHWLRHTAGSHMSDQQVDLRFVRDNFGHASLATTSVYLHAEDDARHQATQASHRLGWN
>Mature_396_residues
THPVPSFNGPAVAIEQLRIPPALSGLHGANRAREASRQITADDDLAAVAAWLARYAGVPGTVATYRKEAERLILWAILQH
GKPLSSLTHEDLLLYERFLADPQPAWRWVMASRKKLARSSPDWRPFAGPLSPTSVRHAMTILNALFAWLVQAGYLAGNPL
SLARRRSAKTAPRVTRYLTHAHWDIVKATIETLPVATERDRLHAARCRWLFSVLYLAGLRLAEIASTRMGAVFSRRDAAG
VERWWIEVHGKGGKTRLVPATDELIAELARYRRICGLPPSPQIGETRPLLLPVIGPEKPLSRAAIHLIVKEVFKLAADRV
RAQGPEFGAQADVLASASSHWLRHTAGSHMSDQQVDLRFVRDNFGHASLATTSVYLHAEDDARHQATQASHRLGWN

Specific function: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The xerC-xerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell div

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family. XerC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790244, Length=249, Percent_Identity=29.3172690763052, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1789261, Length=266, Percent_Identity=26.3157894736842, Blast_Score=65, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR010998
- InterPro:   IPR023109
- InterPro:   IPR004107
- InterPro:   IPR011931 [H]

Pfam domain/function: PF02899 Phage_integr_N; PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 44013; Mature: 43882

Theoretical pI: Translated: 10.81; Mature: 10.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTHPVPSFNGPAVAIEQLRIPPALSGLHGANRAREASRQITADDDLAAVAAWLARYAGVP
CCCCCCCCCCCHHHHHHHCCCHHHHCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCC
GTVATYRKEAERLILWAILQHGKPLSSLTHEDLLLYERFLADPQPAWRWVMASRKKLARS
CHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHC
SPDWRPFAGPLSPTSVRHAMTILNALFAWLVQAGYLAGNPLSLARRRSAKTAPRVTRYLT
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCHHHHHHHHH
HAHWDIVKATIETLPVATERDRLHAARCRWLFSVLYLAGLRLAEIASTRMGAVFSRRDAA
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GVERWWIEVHGKGGKTRLVPATDELIAELARYRRICGLPPSPQIGETRPLLLPVIGPEKP
CCEEEEEEEECCCCCEEECCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCCH
LSRAAIHLIVKEVFKLAADRVRAQGPEFGAQADVLASASSHWLRHTAGSHMSDQQVDLRF
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHH
VRDNFGHASLATTSVYLHAEDDARHQATQASHRLGWN
HHCCCCCCEEEEEEEEEEECCHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
THPVPSFNGPAVAIEQLRIPPALSGLHGANRAREASRQITADDDLAAVAAWLARYAGVP
CCCCCCCCCCHHHHHHHCCCHHHHCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCC
GTVATYRKEAERLILWAILQHGKPLSSLTHEDLLLYERFLADPQPAWRWVMASRKKLARS
CHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHC
SPDWRPFAGPLSPTSVRHAMTILNALFAWLVQAGYLAGNPLSLARRRSAKTAPRVTRYLT
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCHHHHHHHHH
HAHWDIVKATIETLPVATERDRLHAARCRWLFSVLYLAGLRLAEIASTRMGAVFSRRDAA
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GVERWWIEVHGKGGKTRLVPATDELIAELARYRRICGLPPSPQIGETRPLLLPVIGPEKP
CCEEEEEEEECCCCCEEECCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCCH
LSRAAIHLIVKEVFKLAADRVRAQGPEFGAQADVLASASSHWLRHTAGSHMSDQQVDLRF
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHH
VRDNFGHASLATTSVYLHAEDDARHQATQASHRLGWN
HHCCCCCCEEEEEEEEEEECCHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA