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The map label for this gene is xerC [H]

Identifier: 187928591

GI number: 187928591

Start: 1597420

End: 1599534

Strand: Direct

Name: xerC [H]

Synonym: Rpic_1507

Alternate gene names: 187928591

Gene position: 1597420-1599534 (Clockwise)

Preceding gene: 187928585

Following gene: 187928592

Centisome position: 40.52

GC content: 68.51

Gene sequence:

>2115_bases
ATGGACCCGCTCGACCCCGACCACAACCCTGAACCACCCCCCAGCCTCGAGACGCTGCAAAGTGAAATAAAGCGCACTCG
ACCCACCCGCCGCCGCGTTGTCGTTCGACGCCACCTCCACCGTGGCCATTTCGCGTTCCTGCGCGCGGTCGTCCAGGGGC
TGGATGCCCGGCCGATGTGGGCGCGCTACCTGGCCATCGATGGCGAACTGGAGGCGCAGGCCGAGCTGACGCAGGAGACC
TTCGTCGCGCACCCGAAGGTACGGCGCATGACCGCCTGGCTGCGCGCTGAACTGGCGGCGGCCGTGCGCCGCGCCGGCCA
CTACGGCAAGGTGCGCCTGATCCGCATCGACCTCTCCGGCCTTGCGCAGCGCGGACCCGCGTTGCCAGCGCTGGAGGAGT
TCGCGCTGGAGAACGGGCTGGATGACTTCAGCATCGAGGAGCAGCTCGAAGCCTATCGGGAGCGCTTCGGAGACGCGGTG
CAGCGGGCCGAGCGCCGGACCAAGCTGATGGAGCGGCAGCTGCGCCTGCTGGCCGACCTGGAACAGGTGCTGGCGGAGCC
GGTGCGGGTCGACGACCACTGCCACGCGTGGCTGGCCGCGGGCGTCGCGGATCGGCTGGAGGCCGCCGGCGTAGCCACCA
TCGGCACCCTGATCGACCGTATCAACAGCCTGGGCGGCGGCTGGTTCCGCGCGCTGCGCGGGGTCGGCGAGAAGAAAGCC
CACGCCATCGAGCGCTTCCTGCGCGCGAACGCCGACACGCTGGCGCGCAAACTGGGCGAACACGCCCGGATCCCGCGCCG
GCAACTCACCGCGCACGAGCGTGACCGCGTGGTGGCATCCGGCACTGGCCTCCTGCCCCTGGAAAAGATCGTTGTGCCGG
CCGCGCTCGACGGCAGTAACGGCCGTTTCCGGCGGCCCCCGGTCGAGTGCCTGCTGGACGCCCAGAACGACTACGAGGCG
GTACTCACCTGGCTGCGCTCGAAACCGGGGCTGCCGCCTGCCGAGATCGCCCGGCGGCGCACCGGCCGGCGCGATGTCAT
CACCGAGCCCGGCCCGCTGGATTGGCTGCACTACCTGTCCAACACCCAGCGCAGTTATCGCAAGGAGGCAGAACGCTTTC
TGCTGTGGGCCATCTGGATTCGGCGCAAGCCGCTCTCGTCGATGACGACTGAGGACTGCGTCGCCTACCGCGATTTCCTG
GCCGACGTGCCCGACGACTGGTGTGCGCCACGCTCTCGGGAACGGTGGACGCCGAGCTGGAAACCGTTCGAGGGCAAGCT
GTCGCCCGAGTCGCAGGCCTATGCCCTGACCGTGCTGCAGAACCTGTACCGGTACCTCAACGACAAGAACTATCTGAGCG
GCAATCCGTGGGGCGGCGTGCGGGCGACGAATGGTGGCAAACCACAGCTGGACGTTGGGCGCAGTCTGACCGAGGACCAA
TGGGCGTTTGTGGTGGAGCGCCTGTTCCTGCTGGAGCGCACGTCATCGAACCTGCGGCTGCAGGTCGCCTTGCCCTTGCT
CTACGCCACGGGCTTGCGTCTCGCGGAGATCGTGGGAGCGACAACGGCCGACCTGGCATGGCGCAGTCTCGCCCTCCCCC
GCTCCGGCGAACGCATGGACGGCTGGTGGCTGACCGTGGTCGGCAAGGGGTCGCGTGTACGTGAGGTGCCAGTGCCCGAT
GAGGTCGTGCACGCGCTGGGCGCGTACCTGGACTCCCGCGGCTTCCCCAGCGACCCCGCCCAGATTCGTGAGCCGGTGGC
CCTGCTCGGCCACGCGACCGATCAGGCTGAGCGTGCGCCGTGGGCAAAGCGGGACACGGCGAGCCCTGCCGCTCCGCTGA
CGCCGGGTGTGCTCTACCGGCAGATCAAGCGCTTCTTCCAGGCCTGCGCAACCGAGTTGGAGGCAACCGATCCGCAGGGA
GCAGCACGGCTGAACGAAGCCAGCACGCACTGGCTGCGACACTCACACGCATCACATGCCATTGCCGCCGGCACGCCGGT
CGAGATCATGCAGCAGAACCTGGGGCACAAGTCGCTCGACACCACGACGGTCTACGTGACGTCGGAAGAGGCCATTCGGA
TGAAGGAGCTGCGGGGGTTTTGGAAGCGTTCGTGA

Upstream 100 bases:

>100_bases
TTATCATGTACTGTGAAATTAATGTACGCTTTCGAGAACGTCACTTTTTCGCGTTTTCCAACAGGCCCGGAAACCCAAGC
CCGACAACGCTTCGCCGCCC

Downstream 100 bases:

>100_bases
TTTTCGAATGCGGGGGCCGCAACTTCCCCGTCTTTGCAGGCTTAGCCGGCACTGTCCTTAAGCTGGCGCCAAGATCAAAC
GAAGCCCGTCCTTCATTGGG

Product: integrase family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 704; Mature: 704

Protein sequence:

>704_residues
MDPLDPDHNPEPPPSLETLQSEIKRTRPTRRRVVVRRHLHRGHFAFLRAVVQGLDARPMWARYLAIDGELEAQAELTQET
FVAHPKVRRMTAWLRAELAAAVRRAGHYGKVRLIRIDLSGLAQRGPALPALEEFALENGLDDFSIEEQLEAYRERFGDAV
QRAERRTKLMERQLRLLADLEQVLAEPVRVDDHCHAWLAAGVADRLEAAGVATIGTLIDRINSLGGGWFRALRGVGEKKA
HAIERFLRANADTLARKLGEHARIPRRQLTAHERDRVVASGTGLLPLEKIVVPAALDGSNGRFRRPPVECLLDAQNDYEA
VLTWLRSKPGLPPAEIARRRTGRRDVITEPGPLDWLHYLSNTQRSYRKEAERFLLWAIWIRRKPLSSMTTEDCVAYRDFL
ADVPDDWCAPRSRERWTPSWKPFEGKLSPESQAYALTVLQNLYRYLNDKNYLSGNPWGGVRATNGGKPQLDVGRSLTEDQ
WAFVVERLFLLERTSSNLRLQVALPLLYATGLRLAEIVGATTADLAWRSLALPRSGERMDGWWLTVVGKGSRVREVPVPD
EVVHALGAYLDSRGFPSDPAQIREPVALLGHATDQAERAPWAKRDTASPAAPLTPGVLYRQIKRFFQACATELEATDPQG
AARLNEASTHWLRHSHASHAIAAGTPVEIMQQNLGHKSLDTTTVYVTSEEAIRMKELRGFWKRS

Sequences:

>Translated_704_residues
MDPLDPDHNPEPPPSLETLQSEIKRTRPTRRRVVVRRHLHRGHFAFLRAVVQGLDARPMWARYLAIDGELEAQAELTQET
FVAHPKVRRMTAWLRAELAAAVRRAGHYGKVRLIRIDLSGLAQRGPALPALEEFALENGLDDFSIEEQLEAYRERFGDAV
QRAERRTKLMERQLRLLADLEQVLAEPVRVDDHCHAWLAAGVADRLEAAGVATIGTLIDRINSLGGGWFRALRGVGEKKA
HAIERFLRANADTLARKLGEHARIPRRQLTAHERDRVVASGTGLLPLEKIVVPAALDGSNGRFRRPPVECLLDAQNDYEA
VLTWLRSKPGLPPAEIARRRTGRRDVITEPGPLDWLHYLSNTQRSYRKEAERFLLWAIWIRRKPLSSMTTEDCVAYRDFL
ADVPDDWCAPRSRERWTPSWKPFEGKLSPESQAYALTVLQNLYRYLNDKNYLSGNPWGGVRATNGGKPQLDVGRSLTEDQ
WAFVVERLFLLERTSSNLRLQVALPLLYATGLRLAEIVGATTADLAWRSLALPRSGERMDGWWLTVVGKGSRVREVPVPD
EVVHALGAYLDSRGFPSDPAQIREPVALLGHATDQAERAPWAKRDTASPAAPLTPGVLYRQIKRFFQACATELEATDPQG
AARLNEASTHWLRHSHASHAIAAGTPVEIMQQNLGHKSLDTTTVYVTSEEAIRMKELRGFWKRS
>Mature_704_residues
MDPLDPDHNPEPPPSLETLQSEIKRTRPTRRRVVVRRHLHRGHFAFLRAVVQGLDARPMWARYLAIDGELEAQAELTQET
FVAHPKVRRMTAWLRAELAAAVRRAGHYGKVRLIRIDLSGLAQRGPALPALEEFALENGLDDFSIEEQLEAYRERFGDAV
QRAERRTKLMERQLRLLADLEQVLAEPVRVDDHCHAWLAAGVADRLEAAGVATIGTLIDRINSLGGGWFRALRGVGEKKA
HAIERFLRANADTLARKLGEHARIPRRQLTAHERDRVVASGTGLLPLEKIVVPAALDGSNGRFRRPPVECLLDAQNDYEA
VLTWLRSKPGLPPAEIARRRTGRRDVITEPGPLDWLHYLSNTQRSYRKEAERFLLWAIWIRRKPLSSMTTEDCVAYRDFL
ADVPDDWCAPRSRERWTPSWKPFEGKLSPESQAYALTVLQNLYRYLNDKNYLSGNPWGGVRATNGGKPQLDVGRSLTEDQ
WAFVVERLFLLERTSSNLRLQVALPLLYATGLRLAEIVGATTADLAWRSLALPRSGERMDGWWLTVVGKGSRVREVPVPD
EVVHALGAYLDSRGFPSDPAQIREPVALLGHATDQAERAPWAKRDTASPAAPLTPGVLYRQIKRFFQACATELEATDPQG
AARLNEASTHWLRHSHASHAIAAGTPVEIMQQNLGHKSLDTTTVYVTSEEAIRMKELRGFWKRS

Specific function: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The xerC-xerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell div

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family. XerC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789261, Length=270, Percent_Identity=27.4074074074074, Blast_Score=72, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR010998
- InterPro:   IPR023109
- InterPro:   IPR004107 [H]

Pfam domain/function: PF02899 Phage_integr_N; PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 79328; Mature: 79328

Theoretical pI: Translated: 9.74; Mature: 9.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDPLDPDHNPEPPPSLETLQSEIKRTRPTRRRVVVRRHLHRGHFAFLRAVVQGLDARPMW
CCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHCHHHHHHHHHHHCCCCCCHH
ARYLAIDGELEAQAELTQETFVAHPKVRRMTAWLRAELAAAVRRAGHYGKVRLIRIDLSG
HHHEEECCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEHHH
LAQRGPALPALEEFALENGLDDFSIEEQLEAYRERFGDAVQRAERRTKLMERQLRLLADL
HHHCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EQVLAEPVRVDDHCHAWLAAGVADRLEAAGVATIGTLIDRINSLGGGWFRALRGVGEKKA
HHHHHCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCHHHHHHHHCCCHHHH
HAIERFLRANADTLARKLGEHARIPRRQLTAHERDRVVASGTGLLPLEKIVVPAALDGSN
HHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHHCCEEECCCCCCCHHHHHEECEEECCC
GRFRRPPVECLLDAQNDYEAVLTWLRSKPGLPPAEIARRRTGRRDVITEPGPLDWLHYLS
CCCCCCHHHHHCCCCCCHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCCCCHHHHHHHH
NTQRSYRKEAERFLLWAIWIRRKPLSSMTTEDCVAYRDFLADVPDDWCAPRSRERWTPSW
HHHHHHHHHHHHHHHHHHHHHCCCCHHCCHHHHHHHHHHHHCCCCHHCCCCCCCCCCCCC
KPFEGKLSPESQAYALTVLQNLYRYLNDKNYLSGNPWGGVRATNGGKPQLDVGRSLTEDQ
CCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCHHH
WAFVVERLFLLERTSSNLRLQVALPLLYATGLRLAEIVGATTADLAWRSLALPRSGERMD
HHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCC
GWWLTVVGKGSRVREVPVPDEVVHALGAYLDSRGFPSDPAQIREPVALLGHATDQAERAP
CEEEEEEECCCCEEECCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCHHHHCC
WAKRDTASPAAPLTPGVLYRQIKRFFQACATELEATDPQGAARLNEASTHWLRHSHASHA
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCC
IAAGTPVEIMQQNLGHKSLDTTTVYVTSEEAIRMKELRGFWKRS
CCCCCCHHHHHHHCCCCCCCCEEEEEECHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MDPLDPDHNPEPPPSLETLQSEIKRTRPTRRRVVVRRHLHRGHFAFLRAVVQGLDARPMW
CCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHCHHHHHHHHHHHCCCCCCHH
ARYLAIDGELEAQAELTQETFVAHPKVRRMTAWLRAELAAAVRRAGHYGKVRLIRIDLSG
HHHEEECCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEHHH
LAQRGPALPALEEFALENGLDDFSIEEQLEAYRERFGDAVQRAERRTKLMERQLRLLADL
HHHCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EQVLAEPVRVDDHCHAWLAAGVADRLEAAGVATIGTLIDRINSLGGGWFRALRGVGEKKA
HHHHHCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCHHHHHHHHCCCHHHH
HAIERFLRANADTLARKLGEHARIPRRQLTAHERDRVVASGTGLLPLEKIVVPAALDGSN
HHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHHCCEEECCCCCCCHHHHHEECEEECCC
GRFRRPPVECLLDAQNDYEAVLTWLRSKPGLPPAEIARRRTGRRDVITEPGPLDWLHYLS
CCCCCCHHHHHCCCCCCHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCCCCHHHHHHHH
NTQRSYRKEAERFLLWAIWIRRKPLSSMTTEDCVAYRDFLADVPDDWCAPRSRERWTPSW
HHHHHHHHHHHHHHHHHHHHHCCCCHHCCHHHHHHHHHHHHCCCCHHCCCCCCCCCCCCC
KPFEGKLSPESQAYALTVLQNLYRYLNDKNYLSGNPWGGVRATNGGKPQLDVGRSLTEDQ
CCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCHHH
WAFVVERLFLLERTSSNLRLQVALPLLYATGLRLAEIVGATTADLAWRSLALPRSGERMD
HHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCC
GWWLTVVGKGSRVREVPVPDEVVHALGAYLDSRGFPSDPAQIREPVALLGHATDQAERAP
CEEEEEEECCCCEEECCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCHHHHCC
WAKRDTASPAAPLTPGVLYRQIKRFFQACATELEATDPQGAARLNEASTHWLRHSHASHA
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCC
IAAGTPVEIMQQNLGHKSLDTTTVYVTSEEAIRMKELRGFWKRS
CCCCCCHHHHHHHCCCCCCCCEEEEEECHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12828649 [H]