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The map label for this gene is cbdA [H]

Identifier: 187928451

GI number: 187928451

Start: 1462268

End: 1463626

Strand: Direct

Name: cbdA [H]

Synonym: Rpic_1364

Alternate gene names: 187928451

Gene position: 1462268-1463626 (Clockwise)

Preceding gene: 187928450

Following gene: 187928452

Centisome position: 37.09

GC content: 60.71

Gene sequence:

>1359_bases
ATGTCCGCCTTGATCGACAAAGCCAACGAACTGGATCACCTGCTCTCAACCGCGGTGGTGGATGACGAAGAGGCGGGCAT
CTTCCGCTGCCGCCGAGACATCTTCACCAACCCCGATCTGTTCGAACTGGAGATGAAGCACATCTTCGAGAACAACTGGG
TGTATCTCGCGCACGAAAGCCAGATTCCGAACAACAACGATTACTACACCACGTGGATCGGTCGCCAGCCGATCGTCATC
ACCCGCGACAAGACGGGTGAGCTGAACGCGGTCATCAACGCCTGCGCACACAAGGGCGCGATGCTCTGCCGTCGGAAGCA
CGGCAACAAGGGCAGCTTCACGTGCCCGTTCCACGGCTGGACGTTCTCCAACACCGGCAAGCTGCTCAAGGTGAAGGACG
AGAAGACCACCGAGTATCCGGTGCAGTTCAACACGCACGGGTCGCACGATCTGAAAAAGGTCGCGCGGTTCGAGAACTAT
CGCGGCTTCCTGTTCGGCAGCCTCAACGCCGATGTGCAACCGCTCGAAACCTACCTTGGCGAAGCGCGCGTGATCATCGA
CCAGATCGTCGACCAAGCGCCCGAAGGCCTGGAATTGCTGCGCGGCAACTCCACGTACGTCTATGACGGCAACTGGAAGA
TGCAGATGGAGAACGGCTGCGACGGCTACCACGTCAGCACCGTGCACTGGAACTACGCCGCAACGATGGGCCGGCGCAAG
GAAGGTGGCACCCAGGCCGTGGATGCGAACAGCTGGAGCAAGTCGGTGGCGGGCGTCTACGGGTTCGAGCATGGCCACAT
CCTGCTGTGGACCAGGACGATGAACCCGGAAGTGCGGCCCGTCTATGCGCACCGTGACGAAATCAAGGCGCGCGTAGGCG
ACATCAAAGCGGACTTCATCGTCAACCAGACCCGCAACCTGTGCCTGTATCCGAACGTGTTCCTGATGGATCAGTTCAGC
ACGCAGATTCGCGTGGTACGCCCGATCAGTGTCGACAAGACCGAGGTCTCGATCTTCTGTTTCGCGCCGAAGGGCGAGAG
CGCGACCGACCGCGCAACGCGCATCCGCCAGTACGAGGATTTCTTCAACGTCACCGGCATGGGCACCGCCGACGACCTCG
AAGAGTTCCGCGCCTGCCAGAACGGCTATGCCGGCACCACTGCGCTGTGGAACGACCTGTCGCGCGGCGCACCGCTGTGG
GTGCACGGCCCCGACGAGAACGCCACCAAGATGGGCCTGAAGCCGCTTATCTCGGGTGAACGCAGTGAAGACGAGGGGCT
GTTCGTCTGCCAGCACGAATATTGGGTACAAGTCATGCGCGAGGCTCTGAAGAAAGAAAGCGAAGGAGTGGCGGCATGA

Upstream 100 bases:

>100_bases
GTGCTGACGCCGCTGGTGCAGGGCAAGGACAACCAGCGCGTGAACCGCCTGCGTGCTTCGGCCGAGGCCTGAGACCCAAG
ACCTCAACGTGGAGACGACC

Downstream 100 bases:

>100_bases
GCTCCAATTACCACAACATCTGCGCGGCTCTGTACCGTGAAGCGCGGCTGCTCGACGACCGCCAGTGGGACGCTTGGCTG
GAGTGCTACGCGGAGGACGT

Product: Rieske (2Fe-2S) domain-containing protein

Products: NA

Alternate protein names: 2-chlorobenzoate 1,2-dioxygenase [H]

Number of amino acids: Translated: 452; Mature: 451

Protein sequence:

>452_residues
MSALIDKANELDHLLSTAVVDDEEAGIFRCRRDIFTNPDLFELEMKHIFENNWVYLAHESQIPNNNDYYTTWIGRQPIVI
TRDKTGELNAVINACAHKGAMLCRRKHGNKGSFTCPFHGWTFSNTGKLLKVKDEKTTEYPVQFNTHGSHDLKKVARFENY
RGFLFGSLNADVQPLETYLGEARVIIDQIVDQAPEGLELLRGNSTYVYDGNWKMQMENGCDGYHVSTVHWNYAATMGRRK
EGGTQAVDANSWSKSVAGVYGFEHGHILLWTRTMNPEVRPVYAHRDEIKARVGDIKADFIVNQTRNLCLYPNVFLMDQFS
TQIRVVRPISVDKTEVSIFCFAPKGESATDRATRIRQYEDFFNVTGMGTADDLEEFRACQNGYAGTTALWNDLSRGAPLW
VHGPDENATKMGLKPLISGERSEDEGLFVCQHEYWVQVMREALKKESEGVAA

Sequences:

>Translated_452_residues
MSALIDKANELDHLLSTAVVDDEEAGIFRCRRDIFTNPDLFELEMKHIFENNWVYLAHESQIPNNNDYYTTWIGRQPIVI
TRDKTGELNAVINACAHKGAMLCRRKHGNKGSFTCPFHGWTFSNTGKLLKVKDEKTTEYPVQFNTHGSHDLKKVARFENY
RGFLFGSLNADVQPLETYLGEARVIIDQIVDQAPEGLELLRGNSTYVYDGNWKMQMENGCDGYHVSTVHWNYAATMGRRK
EGGTQAVDANSWSKSVAGVYGFEHGHILLWTRTMNPEVRPVYAHRDEIKARVGDIKADFIVNQTRNLCLYPNVFLMDQFS
TQIRVVRPISVDKTEVSIFCFAPKGESATDRATRIRQYEDFFNVTGMGTADDLEEFRACQNGYAGTTALWNDLSRGAPLW
VHGPDENATKMGLKPLISGERSEDEGLFVCQHEYWVQVMREALKKESEGVAA
>Mature_451_residues
SALIDKANELDHLLSTAVVDDEEAGIFRCRRDIFTNPDLFELEMKHIFENNWVYLAHESQIPNNNDYYTTWIGRQPIVIT
RDKTGELNAVINACAHKGAMLCRRKHGNKGSFTCPFHGWTFSNTGKLLKVKDEKTTEYPVQFNTHGSHDLKKVARFENYR
GFLFGSLNADVQPLETYLGEARVIIDQIVDQAPEGLELLRGNSTYVYDGNWKMQMENGCDGYHVSTVHWNYAATMGRRKE
GGTQAVDANSWSKSVAGVYGFEHGHILLWTRTMNPEVRPVYAHRDEIKARVGDIKADFIVNQTRNLCLYPNVFLMDQFST
QIRVVRPISVDKTEVSIFCFAPKGESATDRATRIRQYEDFFNVTGMGTADDLEEFRACQNGYAGTTALWNDLSRGAPLWV
HGPDENATKMGLKPLISGERSEDEGLFVCQHEYWVQVMREALKKESEGVAA

Specific function: Component of 2-halobenzoate dioxygenase multicomponent enzyme system which catalyzes the incorporation of both atoms of molecular oxygen into 2-halobenzoate to form catechol [H]

COG id: COG4638

COG function: function code PR; Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 Rieske domain [H]

Homologues:

Organism=Escherichia coli, GI1788888, Length=373, Percent_Identity=28.4182305630027, Blast_Score=157, Evalue=1e-39,
Organism=Escherichia coli, GI1788103, Length=204, Percent_Identity=27.4509803921569, Blast_Score=90, Evalue=3e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017941
- InterPro:   IPR015881
- InterPro:   IPR015879
- InterPro:   IPR001663 [H]

Pfam domain/function: PF00355 Rieske; PF00848 Ring_hydroxyl_A [H]

EC number: =1.14.12.13 [H]

Molecular weight: Translated: 51304; Mature: 51173

Theoretical pI: Translated: 6.12; Mature: 6.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSALIDKANELDHLLSTAVVDDEEAGIFRCRRDIFTNPDLFELEMKHIFENNWVYLAHES
CCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCEEEHHHHHHHCCCCEEEEECC
QIPNNNDYYTTWIGRQPIVITRDKTGELNAVINACAHKGAMLCRRKHGNKGSFTCPFHGW
CCCCCCCEEEEEECCCCEEEECCCCCCHHHHHHHHHHCCHHHHHHCCCCCCCEEECCCCC
TFSNTGKLLKVKDEKTTEYPVQFNTHGSHDLKKVARFENYRGFLFGSLNADVQPLETYLG
EECCCCCEEEEECCCCCCCCEEECCCCCHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHC
EARVIIDQIVDQAPEGLELLRGNSTYVYDGNWKMQMENGCDGYHVSTVHWNYAATMGRRK
HHHHHHHHHHHCCCCCHHHHCCCCEEEECCCEEEEECCCCCCEEEEEEEEEHHHHCCCCC
EGGTQAVDANSWSKSVAGVYGFEHGHILLWTRTMNPEVRPVYAHRDEIKARVGDIKADFI
CCCCCEEECCCHHHHHHHHEEECCCEEEEEEECCCCCCEEEECCHHHHHHHHCCEEEEEE
VNQTRNLCLYPNVFLMDQFSTQIRVVRPISVDKTEVSIFCFAPKGESATDRATRIRQYED
EECCCCEEECCCEEEEECCCCEEEEEEECCCCCEEEEEEEECCCCCCCHHHHHHHHHHHH
FFNVTGMGTADDLEEFRACQNGYAGTTALWNDLSRGAPLWVHGPDENATKMGLKPLISGE
HHCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHCCCCCEEEECCCCCCHHHCCHHHCCCC
RSEDEGLFVCQHEYWVQVMREALKKESEGVAA
CCCCCCEEEECHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
SALIDKANELDHLLSTAVVDDEEAGIFRCRRDIFTNPDLFELEMKHIFENNWVYLAHES
CCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCEEEHHHHHHHCCCCEEEEECC
QIPNNNDYYTTWIGRQPIVITRDKTGELNAVINACAHKGAMLCRRKHGNKGSFTCPFHGW
CCCCCCCEEEEEECCCCEEEECCCCCCHHHHHHHHHHCCHHHHHHCCCCCCCEEECCCCC
TFSNTGKLLKVKDEKTTEYPVQFNTHGSHDLKKVARFENYRGFLFGSLNADVQPLETYLG
EECCCCCEEEEECCCCCCCCEEECCCCCHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHC
EARVIIDQIVDQAPEGLELLRGNSTYVYDGNWKMQMENGCDGYHVSTVHWNYAATMGRRK
HHHHHHHHHHHCCCCCHHHHCCCCEEEECCCEEEEECCCCCCEEEEEEEEEHHHHCCCCC
EGGTQAVDANSWSKSVAGVYGFEHGHILLWTRTMNPEVRPVYAHRDEIKARVGDIKADFI
CCCCCEEECCCHHHHHHHHEEECCCEEEEEEECCCCCCEEEECCHHHHHHHHCCEEEEEE
VNQTRNLCLYPNVFLMDQFSTQIRVVRPISVDKTEVSIFCFAPKGESATDRATRIRQYED
EECCCCEEECCCEEEEECCCCEEEEEEECCCCCEEEEEEEECCCCCCCHHHHHHHHHHHH
FFNVTGMGTADDLEEFRACQNGYAGTTALWNDLSRGAPLWVHGPDENATKMGLKPLISGE
HHCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHCCCCCEEEECCCCCCHHHCCHHHCCCC
RSEDEGLFVCQHEYWVQVMREALKKESEGVAA
CCCCCCEEEECHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7530709; 1370284 [H]