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The map label for this gene is aroG [H]

Identifier: 187928430

GI number: 187928430

Start: 1436929

End: 1438059

Strand: Direct

Name: aroG [H]

Synonym: Rpic_1342

Alternate gene names: 187928430

Gene position: 1436929-1438059 (Clockwise)

Preceding gene: 187928429

Following gene: 187928431

Centisome position: 36.45

GC content: 65.61

Gene sequence:

>1131_bases
ATGAAGAACCTCGACAACCCATCGCATGATCGCGAGGTGGGCGTTGCCGACGGCACGCAAGACACGACGCGTATCGACGA
CACCCGCATCGGTGCGGTGCGTCCGCTGATTTCTCCGGCGCTGCTGCTGGACGAGCTGCCCGTGCCGGCCGATACGCAGA
CGCTCGTTGAAGACACCCGCCGTGCCATCAGCAACATCCTGCACGGCCGTGACGATCGGTTGCTGCTGATCGTCGGCCCG
TGCTCGATCCACGATCACGATCAGGCGCTCGATTACGCGCGCCGCCTCAAGGCTGCGGCCGATGCGCTGAAGGACGACCT
GCTGATCGTGATGCGCGTCTACTTCGAGAAGCCGCGCACGACGGTCGGTTGGAAGGGTTACATCAACGACCCGCGCCTGG
ACGGCAGCTTCCGCATCAATGAAGGGCTGCGCGCTGCGCGGCAACTGCTGCTCGACGTCAACGCGCTCGGGCTGCCCGCC
GCGACGGAATTCCTCGACCTGCTGAGCCCCCAATACATCGCGGACCTCATCGCATGGGGCGCGATCGGTGCGCGCACGAC
AGAAAGCCAGAGCCATCGACAGCTGGCCTCGGGTCTGAGCTGCCCCATCGGTTTCAAGAACGGCACGGACGGCGGCGTGC
AGGTCGCGTCGGACGCGATCATCGCGGCGCGCGCCAGCCACGCGTTCATGGGGATGACGAAGATGGGCATGGCCGCGATC
TTCGAGACGCGCGGTAACGACGACGCGCACGTGATCCTGCGCGGCGGCAAGGGCGGGCCGAACTACGGCAGCGAGCACAT
CGAGGCGGCCTGCGCGGCGCTGCGCGCGGCAAAGTTGCGCGAACAGGTCATGGTGGACTGCTCGCACGCAAACTCAAACA
AGTCGCATGAACGTCAGATCGACGTTGCGCAAGATCTCGCGCGGCAACTCTCGCAGGGCGAGCGCAGGATCGTCGGCGTG
ATGGTCGAAAGCAATCTCGAAGCGGGCCGCCAAGACCTGAAACCGGGTGTGCCGCTCAAGTACGGCGTGTCGATCACCGA
TGCGTGCCTGAGCTGGACCCAGACGGAGCCCGTACTCGACATACTCGCCGAGGCGGTGCGGCATCGGCGCGCGTATTCGT
ACGACGGGTGA

Upstream 100 bases:

>100_bases
GCGTGGTGACAAGGCCGCTTAAGTGCGTGGCGTAAGTGCGGGATAGCGCGCCATTGACGGCAGGTGCGTGAGTCCCATTT
GAAACCCCTGTGAGATCGCA

Downstream 100 bases:

>100_bases
TGTGACGGCGGCAGGTTCAGGCTTGTCGCCTTTTCCCTATCCATGATGTAGCTCGGCGTTTCAGTGCCATTTCACTGATG
GCCAGCCGCTGCACATTCGC

Product: phospho-2-dehydro-3-deoxyheptonate aldolase

Products: NA

Alternate protein names: 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase; DAHP synthase; Phospho-2-keto-3-deoxyheptonate aldolase [H]

Number of amino acids: Translated: 376; Mature: 376

Protein sequence:

>376_residues
MKNLDNPSHDREVGVADGTQDTTRIDDTRIGAVRPLISPALLLDELPVPADTQTLVEDTRRAISNILHGRDDRLLLIVGP
CSIHDHDQALDYARRLKAAADALKDDLLIVMRVYFEKPRTTVGWKGYINDPRLDGSFRINEGLRAARQLLLDVNALGLPA
ATEFLDLLSPQYIADLIAWGAIGARTTESQSHRQLASGLSCPIGFKNGTDGGVQVASDAIIAARASHAFMGMTKMGMAAI
FETRGNDDAHVILRGGKGGPNYGSEHIEAACAALRAAKLREQVMVDCSHANSNKSHERQIDVAQDLARQLSQGERRIVGV
MVESNLEAGRQDLKPGVPLKYGVSITDACLSWTQTEPVLDILAEAVRHRRAYSYDG

Sequences:

>Translated_376_residues
MKNLDNPSHDREVGVADGTQDTTRIDDTRIGAVRPLISPALLLDELPVPADTQTLVEDTRRAISNILHGRDDRLLLIVGP
CSIHDHDQALDYARRLKAAADALKDDLLIVMRVYFEKPRTTVGWKGYINDPRLDGSFRINEGLRAARQLLLDVNALGLPA
ATEFLDLLSPQYIADLIAWGAIGARTTESQSHRQLASGLSCPIGFKNGTDGGVQVASDAIIAARASHAFMGMTKMGMAAI
FETRGNDDAHVILRGGKGGPNYGSEHIEAACAALRAAKLREQVMVDCSHANSNKSHERQIDVAQDLARQLSQGERRIVGV
MVESNLEAGRQDLKPGVPLKYGVSITDACLSWTQTEPVLDILAEAVRHRRAYSYDG
>Mature_376_residues
MKNLDNPSHDREVGVADGTQDTTRIDDTRIGAVRPLISPALLLDELPVPADTQTLVEDTRRAISNILHGRDDRLLLIVGP
CSIHDHDQALDYARRLKAAADALKDDLLIVMRVYFEKPRTTVGWKGYINDPRLDGSFRINEGLRAARQLLLDVNALGLPA
ATEFLDLLSPQYIADLIAWGAIGARTTESQSHRQLASGLSCPIGFKNGTDGGVQVASDAIIAARASHAFMGMTKMGMAAI
FETRGNDDAHVILRGGKGGPNYGSEHIEAACAALRAAKLREQVMVDCSHANSNKSHERQIDVAQDLARQLSQGERRIVGV
MVESNLEAGRQDLKPGVPLKYGVSITDACLSWTQTEPVLDILAEAVRHRRAYSYDG

Specific function: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) [H]

COG id: COG0722

COG function: function code E; 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I DAHP synthase family [H]

Homologues:

Organism=Escherichia coli, GI1786969, Length=345, Percent_Identity=58.2608695652174, Blast_Score=413, Evalue=1e-117,
Organism=Escherichia coli, GI1787996, Length=346, Percent_Identity=53.1791907514451, Blast_Score=374, Evalue=1e-105,
Organism=Escherichia coli, GI1788953, Length=336, Percent_Identity=51.4880952380952, Blast_Score=359, Evalue=1e-100,
Organism=Saccharomyces cerevisiae, GI6320240, Length=361, Percent_Identity=50.9695290858726, Blast_Score=367, Evalue=1e-102,
Organism=Saccharomyces cerevisiae, GI6319726, Length=351, Percent_Identity=53.8461538461538, Blast_Score=365, Evalue=1e-102,

Paralogues:

None

Copy number: 600 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR006218
- InterPro:   IPR006219 [H]

Pfam domain/function: PF00793 DAHP_synth_1 [H]

EC number: =2.5.1.54 [H]

Molecular weight: Translated: 40914; Mature: 40914

Theoretical pI: Translated: 6.29; Mature: 6.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNLDNPSHDREVGVADGTQDTTRIDDTRIGAVRPLISPALLLDELPVPADTQTLVEDTR
CCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHH
RAISNILHGRDDRLLLIVGPCSIHDHDQALDYARRLKAAADALKDDLLIVMRVYFEKPRT
HHHHHHHCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
TVGWKGYINDPRLDGSFRINEGLRAARQLLLDVNALGLPAATEFLDLLSPQYIADLIAWG
CCCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCHHHHHHHHHHH
AIGARTTESQSHRQLASGLSCPIGFKNGTDGGVQVASDAIIAARASHAFMGMTKMGMAAI
CCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHH
FETRGNDDAHVILRGGKGGPNYGSEHIEAACAALRAAKLREQVMVDCSHANSNKSHERQI
HHCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHEHHCCCCCCCHHHHH
DVAQDLARQLSQGERRIVGVMVESNLEAGRQDLKPGVPLKYGVSITDACLSWTQTEPVLD
HHHHHHHHHHHCCCCEEEEEEEECCHHHHHHHCCCCCCEEECCCHHHHHHHCCCCCHHHH
ILAEAVRHRRAYSYDG
HHHHHHHHHCCCCCCC
>Mature Secondary Structure
MKNLDNPSHDREVGVADGTQDTTRIDDTRIGAVRPLISPALLLDELPVPADTQTLVEDTR
CCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHH
RAISNILHGRDDRLLLIVGPCSIHDHDQALDYARRLKAAADALKDDLLIVMRVYFEKPRT
HHHHHHHCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
TVGWKGYINDPRLDGSFRINEGLRAARQLLLDVNALGLPAATEFLDLLSPQYIADLIAWG
CCCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCHHHHHHHHHHH
AIGARTTESQSHRQLASGLSCPIGFKNGTDGGVQVASDAIIAARASHAFMGMTKMGMAAI
CCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHH
FETRGNDDAHVILRGGKGGPNYGSEHIEAACAALRAAKLREQVMVDCSHANSNKSHERQI
HHCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHEHHCCCCCCCHHHHH
DVAQDLARQLSQGERRIVGVMVESNLEAGRQDLKPGVPLKYGVSITDACLSWTQTEPVLD
HHHHHHHHHHHCCCCEEEEEEEECCHHHHHHHCCCCCCEEECCCHHHHHHHCCCCCHHHH
ILAEAVRHRRAYSYDG
HHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]