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The map label for this gene is cat1 [H]

Identifier: 187928423

GI number: 187928423

Start: 1428563

End: 1430110

Strand: Direct

Name: cat1 [H]

Synonym: Rpic_1335

Alternate gene names: 187928423

Gene position: 1428563-1430110 (Clockwise)

Preceding gene: 187928422

Following gene: 187928426

Centisome position: 36.23

GC content: 62.98

Gene sequence:

>1548_bases
ATGACCTCTGATATTGGCGGCCGCATTCGCCTGCAATCCCTGCTGGACAAAGTGGTGTCTGCGGACGAAGCCGCGACCCT
GATCCACGATGGCATGACGGTCGGCATGAGCGGTTTCACCCGTGCCGGCGACTGCAAGGCCGTGCCGTTTGCCCTGGCCC
GGCGTGCCGCGCACGAGCCGCTGCGCATTACCCTGATGACCGGCGCCTCGCTGGGTAACGACATTGACAAGGTATTGGCC
GAAGCCGATGTGATTGCCCGTCGCCTGCCGTTCCAGGCCGATGCCACCCTTCGGCGCAAGATCAACGCAGGCGAGGTCAT
GTTCATTGACCAGCACTTGTCGGAAACCGTCGAGCAACTGCGTTCGCGGCAGATTGCACCGCTGGATGTGGCGGTTGTCG
AAGCCACGGCCATCACCGAGAACGGCGGCATCGTGCCGACTACGTCGGTCGGTAATTCCGCAAGTTTCGCGGTGCTGGCG
AAGCAGGTGATCGTCGAGATCAACCTGAACATGCCCGCCAATCTGGAAGGGCTGCACGATATCTTCTTTCCGGTGCAGCG
GCCCTATCGCCAGCCGATTCCACTCATTGCAGCGGAGCAGCGCATCGGCCTGCCGTCTATCCCGATCGATCCGCGCAAGA
TCGCTGCCATCGTCATCACGGGGCAGGACGACAGCCCGTCCAACGTGTTGCCGCCCGATGCGGAGACCAATGCCATCGCG
GGGCATCTGAACGCATTCCTGGCGCGCGAGGTGCGCACGGGCCGTCTTTCGCCCACGCTGCAGCCGCTGCAGGCGGGTAT
CGGAACGATCTCCAACGCGGTCCTGCATGGCTTCATCGACTCGCCGTTCCATGACCTCAAGATGTATTCGGAGGTTTTGC
AGGACAGCTCCATCGAGCTGCTCGACTCGGGCAAGCTGGCGTTTGCCTCGGCCTCGTCGATCACGCTGTCACGCCCGGTC
TACAAGCGGTTTCTGTCAGAACTGGAACGCTACAAGACGCGGGTGATTCTGCGACCGCAGGAGATCAGCAACCACCCGGA
AGTGATCCGCCGGTTGGGCCTGATCACCATCAATACCGCGCTGGAATGCGATATCTACGGCAACGTGAATTCGACGCACG
TGGGCGGAACGCACATGATGAACGGCATCGGCGGCTCGGGCGACTTCGCGCGCAACGCGCATCTGTCAGTCTTCGTGACC
AAGTCATTGGCCAAGGCCGGCGACATCTCGAGCATCGTGCCGATGGTCTCGCATGTGGACCATACCGAACACGACGTCGA
CATCATCGTTACCGAACATGGACTGGCCGATCTGCGCGGGTTGGCGCCGCGCGAGCGTGCTGTGCAGATCATCAGCAACT
GCGCTGATCCGCGCTACCGCGAGCTGCTGCGCGACTACGTTGTGCGCGCGCAGCGGCGCGGCGGGCATACGCCCCACCTC
CTGGAGGAGGCGCTGGCCTGGCATGTCCGGTTTCGCGACCAGGGCTCGATGGCCTCAGCCGGGCTCACAGGTGAAAGTCT
GCTCCCGGAACCCGCCCTCAGCGCTTGA

Upstream 100 bases:

>100_bases
CTGCATATCCCAGTGAATAGGCCGAGACCTGCTGACGGGGCGCCCTACATCACAACAAGAAGCGCCAAAGTCAGGCTCGG
CGAAGTACCAAGGAGACGAG

Downstream 100 bases:

>100_bases
CGCGCGTCGCAGCCGCTGCTCAGGCGCCGAGCACTTCCTGGCACGTCGCGAGCCACGCGCGAGCGGCGTGCGACAGGTAG
CGGCCGGGCGACCACAGGTG

Product: succinate CoA transferase

Products: propionate; succinyl-CoA [C]

Alternate protein names: NA

Number of amino acids: Translated: 515; Mature: 514

Protein sequence:

>515_residues
MTSDIGGRIRLQSLLDKVVSADEAATLIHDGMTVGMSGFTRAGDCKAVPFALARRAAHEPLRITLMTGASLGNDIDKVLA
EADVIARRLPFQADATLRRKINAGEVMFIDQHLSETVEQLRSRQIAPLDVAVVEATAITENGGIVPTTSVGNSASFAVLA
KQVIVEINLNMPANLEGLHDIFFPVQRPYRQPIPLIAAEQRIGLPSIPIDPRKIAAIVITGQDDSPSNVLPPDAETNAIA
GHLNAFLAREVRTGRLSPTLQPLQAGIGTISNAVLHGFIDSPFHDLKMYSEVLQDSSIELLDSGKLAFASASSITLSRPV
YKRFLSELERYKTRVILRPQEISNHPEVIRRLGLITINTALECDIYGNVNSTHVGGTHMMNGIGGSGDFARNAHLSVFVT
KSLAKAGDISSIVPMVSHVDHTEHDVDIIVTEHGLADLRGLAPRERAVQIISNCADPRYRELLRDYVVRAQRRGGHTPHL
LEEALAWHVRFRDQGSMASAGLTGESLLPEPALSA

Sequences:

>Translated_515_residues
MTSDIGGRIRLQSLLDKVVSADEAATLIHDGMTVGMSGFTRAGDCKAVPFALARRAAHEPLRITLMTGASLGNDIDKVLA
EADVIARRLPFQADATLRRKINAGEVMFIDQHLSETVEQLRSRQIAPLDVAVVEATAITENGGIVPTTSVGNSASFAVLA
KQVIVEINLNMPANLEGLHDIFFPVQRPYRQPIPLIAAEQRIGLPSIPIDPRKIAAIVITGQDDSPSNVLPPDAETNAIA
GHLNAFLAREVRTGRLSPTLQPLQAGIGTISNAVLHGFIDSPFHDLKMYSEVLQDSSIELLDSGKLAFASASSITLSRPV
YKRFLSELERYKTRVILRPQEISNHPEVIRRLGLITINTALECDIYGNVNSTHVGGTHMMNGIGGSGDFARNAHLSVFVT
KSLAKAGDISSIVPMVSHVDHTEHDVDIIVTEHGLADLRGLAPRERAVQIISNCADPRYRELLRDYVVRAQRRGGHTPHL
LEEALAWHVRFRDQGSMASAGLTGESLLPEPALSA
>Mature_514_residues
TSDIGGRIRLQSLLDKVVSADEAATLIHDGMTVGMSGFTRAGDCKAVPFALARRAAHEPLRITLMTGASLGNDIDKVLAE
ADVIARRLPFQADATLRRKINAGEVMFIDQHLSETVEQLRSRQIAPLDVAVVEATAITENGGIVPTTSVGNSASFAVLAK
QVIVEINLNMPANLEGLHDIFFPVQRPYRQPIPLIAAEQRIGLPSIPIDPRKIAAIVITGQDDSPSNVLPPDAETNAIAG
HLNAFLAREVRTGRLSPTLQPLQAGIGTISNAVLHGFIDSPFHDLKMYSEVLQDSSIELLDSGKLAFASASSITLSRPVY
KRFLSELERYKTRVILRPQEISNHPEVIRRLGLITINTALECDIYGNVNSTHVGGTHMMNGIGGSGDFARNAHLSVFVTK
SLAKAGDISSIVPMVSHVDHTEHDVDIIVTEHGLADLRGLAPRERAVQIISNCADPRYRELLRDYVVRAQRRGGHTPHLL
EEALAWHVRFRDQGSMASAGLTGESLLPEPALSA

Specific function: Forms succinyl-CoA from succinate and acetyl-CoA [H]

COG id: COG0427

COG function: function code C; Acetyl-CoA hydrolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetyl-CoA hydrolase/transferase family [H]

Homologues:

Organism=Escherichia coli, GI1789287, Length=485, Percent_Identity=44.7422680412371, Blast_Score=411, Evalue=1e-116,
Organism=Caenorhabditis elegans, GI17538151, Length=221, Percent_Identity=30.316742081448, Blast_Score=73, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6319456, Length=511, Percent_Identity=44.2270058708415, Blast_Score=410, Evalue=1e-115,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003702
- InterPro:   IPR006472
- InterPro:   IPR017821 [H]

Pfam domain/function: PF02550 AcetylCoA_hydro; PF04223 CitF [H]

EC number: NA

Molecular weight: Translated: 55762; Mature: 55630

Theoretical pI: Translated: 6.61; Mature: 6.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSDIGGRIRLQSLLDKVVSADEAATLIHDGMTVGMSGFTRAGDCKAVPFALARRAAHEP
CCCCCCCCEEHHHHHHHHHCCCHHHHHHHCCEEECCCCCCCCCCCCCHHHHHHHHHCCCC
LRITLMTGASLGNDIDKVLAEADVIARRLPFQADATLRRKINAGEVMFIDQHLSETVEQL
EEEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCCCEEEEHHHHHHHHHHH
RSRQIAPLDVAVVEATAITENGGIVPTTSVGNSASFAVLAKQVIVEINLNMPANLEGLHD
HCCCCCCCEEEEEEEEEEECCCCEEEECCCCCCCHHHHHHEEEEEEEECCCCCCCCHHHH
IFFPVQRPYRQPIPLIAAEQRIGLPSIPIDPRKIAAIVITGQDDSPSNVLPPDAETNAIA
HHHHHCCCCCCCCCEEECCCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCHHH
GHLNAFLAREVRTGRLSPTLQPLQAGIGTISNAVLHGFIDSPFHDLKMYSEVLQDSSIEL
HHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCEEE
LDSGKLAFASASSITLSRPVYKRFLSELERYKTRVILRPQEISNHPEVIRRLGLITINTA
ECCCCEEEECCCCEEECCHHHHHHHHHHHHHHHEEEECHHHHCCCHHHHHHCCEEEEECE
LECDIYGNVNSTHVGGTHMMNGIGGSGDFARNAHLSVFVTKSLAKAGDISSIVPMVSHVD
EEEEEECCCCCCCCCCHHHHCCCCCCCCCCCCCEEEEEEEHHHHHCCCHHHHHHHHHHCC
HTEHDVDIIVTEHGLADLRGLAPRERAVQIISNCADPRYRELLRDYVVRAQRRGGHTPHL
CCCCCEEEEEECCCHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCHHH
LEEALAWHVRFRDQGSMASAGLTGESLLPEPALSA
HHHHHHHHEEECCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TSDIGGRIRLQSLLDKVVSADEAATLIHDGMTVGMSGFTRAGDCKAVPFALARRAAHEP
CCCCCCCEEHHHHHHHHHCCCHHHHHHHCCEEECCCCCCCCCCCCCHHHHHHHHHCCCC
LRITLMTGASLGNDIDKVLAEADVIARRLPFQADATLRRKINAGEVMFIDQHLSETVEQL
EEEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCCCEEEEHHHHHHHHHHH
RSRQIAPLDVAVVEATAITENGGIVPTTSVGNSASFAVLAKQVIVEINLNMPANLEGLHD
HCCCCCCCEEEEEEEEEEECCCCEEEECCCCCCCHHHHHHEEEEEEEECCCCCCCCHHHH
IFFPVQRPYRQPIPLIAAEQRIGLPSIPIDPRKIAAIVITGQDDSPSNVLPPDAETNAIA
HHHHHCCCCCCCCCEEECCCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCHHH
GHLNAFLAREVRTGRLSPTLQPLQAGIGTISNAVLHGFIDSPFHDLKMYSEVLQDSSIEL
HHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCEEE
LDSGKLAFASASSITLSRPVYKRFLSELERYKTRVILRPQEISNHPEVIRRLGLITINTA
ECCCCEEEECCCCEEECCHHHHHHHHHHHHHHHEEEECHHHHCCCHHHHHHCCEEEEECE
LECDIYGNVNSTHVGGTHMMNGIGGSGDFARNAHLSVFVTKSLAKAGDISSIVPMVSHVD
EEEEEECCCCCCCCCCHHHHCCCCCCCCCCCCCEEEEEEEHHHHHCCCHHHHHHHHHHCC
HTEHDVDIIVTEHGLADLRGLAPRERAVQIISNCADPRYRELLRDYVVRAQRRGGHTPHL
CCCCCEEEEEECCCHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCHHH
LEEALAWHVRFRDQGSMASAGLTGESLLPEPALSA
HHHHHHHHEEECCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: propionyl-CoA; succinate [C]

Specific reaction: propionyl-CoA + succinate = propionate + succinyl-CoA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8550525 [H]