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The map label for this gene is tsf

Identifier: 187928368

GI number: 187928368

Start: 1374601

End: 1375479

Strand: Direct

Name: tsf

Synonym: Rpic_1279

Alternate gene names: 187928368

Gene position: 1374601-1375479 (Clockwise)

Preceding gene: 187928367

Following gene: 187928369

Centisome position: 34.87

GC content: 61.09

Gene sequence:

>879_bases
ATGGCGGCAATTACCGCAAGCATGGTTGCAGAGCTGCGCGCAAAGACCGACGCGCCGATGATGGAATGCAAGAAGGCCCT
GACCGAAGCCGAAGGCAACCTGGAAAAGGCTGAAGAGATCCTGCGCGTGAAGCTGGGCAACAAGGCGGGCAAGGCTTCCA
GCCGCGTCACCGCTGAAGGCGTGGTCGCAGCGTTCGTCGAGGGCACCACGGGCGCCCTGGTCGAAGTGAACTGCGAAACC
GACTTCGTCTCGAAGAACGACGATTTCCTGGCTTTCACCAACGAGGTTGCCAAGCTGATCGCTCAGAAGAACCCGGCTGA
CGTGGCTGCCCTGTCGGCCCTGTCGATCGGCGATGAAACGGTCGAAGCCGTGCGCACCCGCCTGATCGGCAAGATCGGCG
AGAACATGACGATCCGCCGCTTCCAGCGTTTCGAAGGCACGCAGCTGACTTCGTATCTGCACGGCACGCGCATTGGCGTG
ATGGTGGCATTCGAAGGCAACGAAGTGGCGGCTAAGGACGCTGCAATGCAGGCTGCCGCCATGAAGCCGGTGTCGCTGTC
GGCTGACGACGTGCCGGCCGAACTGGTCGCCAAGGAGCGCAGCGTTGCTGAGCAGAAGGCTGCTGAATCGGGCAAGCCGG
CTGAAATCGTTGCCAAGATGGTGGAAGGCAGCGTGCAGAAGTACCTGAAGGAAGTGTCGCTGCTGAACCAGCCGTTCGTG
AAGAACGACAAGCAGACCGTTGAGCAGATGCTCAAGGCCGCCAACACGACCGTGAAGGCTTTCACGCTGTACGTGGTGGG
CGAGGGCATCGAGAAGAAGCAAGACGACTTCGCTGCTGAAGTGGCTGCCCAGGTGGCCGCTGCCAAGCAACAGGCGTAA

Upstream 100 bases:

>100_bases
TTTCGTGGGGCGGCCGGATGGAAACCGGACGACAGGCCGGCGCGAGGCGAGGAAGGATCCGCACGCGACCGGACGACGAT
CTGAAACAAGGAGCATGAGA

Downstream 100 bases:

>100_bases
TGCTGCGACGGCCGCTTCCGATGGTGCGGCGATTCGCCCTCCGGCGCAGGCCGGGAGGCGTCGTTTCCACCATTGGCGCA
GCCGTATAATGCCGAACAAA

Product: elongation factor Ts

Products: NA

Alternate protein names: EF-Ts

Number of amino acids: Translated: 292; Mature: 291

Protein sequence:

>292_residues
MAAITASMVAELRAKTDAPMMECKKALTEAEGNLEKAEEILRVKLGNKAGKASSRVTAEGVVAAFVEGTTGALVEVNCET
DFVSKNDDFLAFTNEVAKLIAQKNPADVAALSALSIGDETVEAVRTRLIGKIGENMTIRRFQRFEGTQLTSYLHGTRIGV
MVAFEGNEVAAKDAAMQAAAMKPVSLSADDVPAELVAKERSVAEQKAAESGKPAEIVAKMVEGSVQKYLKEVSLLNQPFV
KNDKQTVEQMLKAANTTVKAFTLYVVGEGIEKKQDDFAAEVAAQVAAAKQQA

Sequences:

>Translated_292_residues
MAAITASMVAELRAKTDAPMMECKKALTEAEGNLEKAEEILRVKLGNKAGKASSRVTAEGVVAAFVEGTTGALVEVNCET
DFVSKNDDFLAFTNEVAKLIAQKNPADVAALSALSIGDETVEAVRTRLIGKIGENMTIRRFQRFEGTQLTSYLHGTRIGV
MVAFEGNEVAAKDAAMQAAAMKPVSLSADDVPAELVAKERSVAEQKAAESGKPAEIVAKMVEGSVQKYLKEVSLLNQPFV
KNDKQTVEQMLKAANTTVKAFTLYVVGEGIEKKQDDFAAEVAAQVAAAKQQA
>Mature_291_residues
AAITASMVAELRAKTDAPMMECKKALTEAEGNLEKAEEILRVKLGNKAGKASSRVTAEGVVAAFVEGTTGALVEVNCETD
FVSKNDDFLAFTNEVAKLIAQKNPADVAALSALSIGDETVEAVRTRLIGKIGENMTIRRFQRFEGTQLTSYLHGTRIGVM
VAFEGNEVAAKDAAMQAAAMKPVSLSADDVPAELVAKERSVAEQKAAESGKPAEIVAKMVEGSVQKYLKEVSLLNQPFVK
NDKQTVEQMLKAANTTVKAFTLYVVGEGIEKKQDDFAAEVAAQVAAAKQQA

Specific function: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome

COG id: COG0264

COG function: function code J; Translation elongation factor Ts

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EF-Ts family

Homologues:

Organism=Homo sapiens, GI171846268, Length=234, Percent_Identity=30.7692307692308, Blast_Score=86, Evalue=4e-17,
Organism=Homo sapiens, GI291084500, Length=255, Percent_Identity=28.2352941176471, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI291084498, Length=100, Percent_Identity=41, Blast_Score=72, Evalue=6e-13,
Organism=Homo sapiens, GI291084502, Length=100, Percent_Identity=41, Blast_Score=72, Evalue=7e-13,
Organism=Escherichia coli, GI1786366, Length=284, Percent_Identity=48.5915492957746, Blast_Score=231, Evalue=4e-62,
Organism=Caenorhabditis elegans, GI17561440, Length=292, Percent_Identity=29.1095890410959, Blast_Score=88, Evalue=5e-18,
Organism=Drosophila melanogaster, GI19921466, Length=294, Percent_Identity=28.9115646258503, Blast_Score=93, Evalue=2e-19,

Paralogues:

None

Copy number: 2670 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1100 Molecules/Cell In: Stationary-Phase, Rich-Media (Based on E. coli). 4173 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 14563 Molecules/Cell In: Growth Phase, Gluco

Swissprot (AC and ID): EFTS_RALPJ (B2UB07)

Other databases:

- EMBL:   CP001068
- RefSeq:   YP_001898855.1
- ProteinModelPortal:   B2UB07
- SMR:   B2UB07
- GeneID:   6289425
- GenomeReviews:   CP001068_GR
- KEGG:   rpi:Rpic_1279
- HOGENOM:   HBG713289
- OMA:   YLHGTRI
- ProtClustDB:   PRK09377
- GO:   GO:0005737
- HAMAP:   MF_00050
- InterPro:   IPR001816
- InterPro:   IPR014039
- InterPro:   IPR018101
- InterPro:   IPR009060
- InterPro:   IPR000449
- Gene3D:   G3DSA:3.30.479.20
- PANTHER:   PTHR11741
- TIGRFAMs:   TIGR00116

Pfam domain/function: PF00889 EF_TS; PF00627 UBA; SSF54713 EF_TS; SSF46934 UBA_like

EC number: NA

Molecular weight: Translated: 31102; Mature: 30971

Theoretical pI: Translated: 5.02; Mature: 5.02

Prosite motif: PS01126 EF_TS_1; PS01127 EF_TS_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAAITASMVAELRAKTDAPMMECKKALTEAEGNLEKAEEILRVKLGNKAGKASSRVTAEG
CCCHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCHHHH
VVAAFVEGTTGALVEVNCETDFVSKNDDFLAFTNEVAKLIAQKNPADVAALSALSIGDET
HHHHHCCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHCCHHH
VEAVRTRLIGKIGENMTIRRFQRFEGTQLTSYLHGTRIGVMVAFEGNEVAAKDAAMQAAA
HHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHCCCEEEEEEEECCCCHHHHHHHHHHHH
MKPVSLSADDVPAELVAKERSVAEQKAAESGKPAEIVAKMVEGSVQKYLKEVSLLNQPFV
CCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCC
KNDKQTVEQMLKAANTTVKAFTLYVVGEGIEKKQDDFAAEVAAQVAAAKQQA
CCCHHHHHHHHHHHCCHHHEEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
AAITASMVAELRAKTDAPMMECKKALTEAEGNLEKAEEILRVKLGNKAGKASSRVTAEG
CCHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCHHHH
VVAAFVEGTTGALVEVNCETDFVSKNDDFLAFTNEVAKLIAQKNPADVAALSALSIGDET
HHHHHCCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHCCHHH
VEAVRTRLIGKIGENMTIRRFQRFEGTQLTSYLHGTRIGVMVAFEGNEVAAKDAAMQAAA
HHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHCCCEEEEEEEECCCCHHHHHHHHHHHH
MKPVSLSADDVPAELVAKERSVAEQKAAESGKPAEIVAKMVEGSVQKYLKEVSLLNQPFV
CCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCC
KNDKQTVEQMLKAANTTVKAFTLYVVGEGIEKKQDDFAAEVAAQVAAAKQQA
CCCHHHHHHHHHHHCCHHHEEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA