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The map label for this gene is dppA [H]

Identifier: 187928346

GI number: 187928346

Start: 1347519

End: 1348334

Strand: Direct

Name: dppA [H]

Synonym: Rpic_1257

Alternate gene names: 187928346

Gene position: 1347519-1348334 (Clockwise)

Preceding gene: 187928345

Following gene: 187928347

Centisome position: 34.18

GC content: 67.77

Gene sequence:

>816_bases
ATGCGAATCCTGATTTCCGCCGACATCGAAGGCGTGGCCAACGTGTTCCACCCCGAGCAGACGCGCGCCGGTAACGGCGA
ATACGAGCGCGCCCGCCGCTGGATGACCGCCGAAGCCGACGCCGCCGTCCGCGGTGCCTTCGACGGTGGCGCCACGGACG
TGCTCGTTAACGATTCGCACGGCGGTTTCCGCAACCTCATCCCCGATTCCATCGACCGCCGCGCACGCTTCGTCCTCGGC
AAGCCGCGCTACCTCAGCATGATGGCCGGCGTGGACGGCTGCGATGCCGTCTGCATGATCGGTTACCACGCGCGCGCCGG
CAGCCGCGGCGTGCTGGCGCACACCATCAACAGCTTTGCGTTTGCGCGCGTCTGGTTCAACGAGCAGGAACTGGGCGAGG
CCGGCCTCTACGGCGCCCTGGCCGGGGAGCGCGGCGTGCCGGTGGCCGTTGCCAGCGGCGACGACGTGTTCATCAAGGAA
ACCAAGCCGCTGCTGCCGCACACCACCTTTGTCGAGACCAAGCAGGCCGAAGGCCACAACGCGGGGACATCGCTCTCGCC
CGAGCAGTCGTGCGAGGCCATCTACGCAGCCGTGAAAGCCACGGTGCAGCGGGGGCATTTCAGCATGCCGCTGCGCCTCC
AGGCGCCGATCGTATGCCGCCTGCAGACGCAAACGCCCGCATTGGCCGACCTGTTCTGCCAATGGCCCGCCCTCGAGCGC
GTCGACGGCACGATGCTGCGCTTCGCCGCCGACTCCGTCGAACATGCCGTGCGCATGCTCAACAGCCTCTCCGCCATGTC
CGCGATGCTGCGTTAA

Upstream 100 bases:

>100_bases
TCGAACAAGCCATCGTGCACGCGCTGTTCCACGCAACAGCCGTCACCGGCCGCGACGGCAACGCCCGCCGCGCACTGACC
GAATTGCTCTGACCTGACCC

Downstream 100 bases:

>100_bases
GCGCCAACTCTTCACGGCACATCAAAGCGTCAGCGCGCGTGCAGACGGTTTGGCCGTTCATGCCCTAGATGGCGCCTTGA
ATTTCTGTAAGCAGGCGGAA

Product: peptidase M55 D-aminopeptidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 271; Mature: 271

Protein sequence:

>271_residues
MRILISADIEGVANVFHPEQTRAGNGEYERARRWMTAEADAAVRGAFDGGATDVLVNDSHGGFRNLIPDSIDRRARFVLG
KPRYLSMMAGVDGCDAVCMIGYHARAGSRGVLAHTINSFAFARVWFNEQELGEAGLYGALAGERGVPVAVASGDDVFIKE
TKPLLPHTTFVETKQAEGHNAGTSLSPEQSCEAIYAAVKATVQRGHFSMPLRLQAPIVCRLQTQTPALADLFCQWPALER
VDGTMLRFAADSVEHAVRMLNSLSAMSAMLR

Sequences:

>Translated_271_residues
MRILISADIEGVANVFHPEQTRAGNGEYERARRWMTAEADAAVRGAFDGGATDVLVNDSHGGFRNLIPDSIDRRARFVLG
KPRYLSMMAGVDGCDAVCMIGYHARAGSRGVLAHTINSFAFARVWFNEQELGEAGLYGALAGERGVPVAVASGDDVFIKE
TKPLLPHTTFVETKQAEGHNAGTSLSPEQSCEAIYAAVKATVQRGHFSMPLRLQAPIVCRLQTQTPALADLFCQWPALER
VDGTMLRFAADSVEHAVRMLNSLSAMSAMLR
>Mature_271_residues
MRILISADIEGVANVFHPEQTRAGNGEYERARRWMTAEADAAVRGAFDGGATDVLVNDSHGGFRNLIPDSIDRRARFVLG
KPRYLSMMAGVDGCDAVCMIGYHARAGSRGVLAHTINSFAFARVWFNEQELGEAGLYGALAGERGVPVAVASGDDVFIKE
TKPLLPHTTFVETKQAEGHNAGTSLSPEQSCEAIYAAVKATVQRGHFSMPLRLQAPIVCRLQTQTPALADLFCQWPALER
VDGTMLRFAADSVEHAVRMLNSLSAMSAMLR

Specific function: Hydrolyzes N-terminal residues in D-amino acid containing peptides. Among the tested substrates, the highest activities are with D-Ala-D-Ala and D-Ala-Gly-Gly. The physiological role is not clear [H]

COG id: COG2362

COG function: function code E; D-aminopeptidase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M55 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007035 [H]

Pfam domain/function: PF04951 Peptidase_M55 [H]

EC number: NA

Molecular weight: Translated: 29366; Mature: 29366

Theoretical pI: Translated: 6.71; Mature: 6.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRILISADIEGVANVFHPEQTRAGNGEYERARRWMTAEADAAVRGAFDGGATDVLVNDSH
CEEEEECCCHHHHHHCCCCCCCCCCCHHHHHHHHCCCCCCHHEEECCCCCCEEEEEECCC
GGFRNLIPDSIDRRARFVLGKPRYLSMMAGVDGCDAVCMIGYHARAGSRGVLAHTINSFA
CCHHHCCCHHHHHHHHEEECCCHHHHHHCCCCCCCEEEEEEEECCCCCCCHHHHHHHHHE
FARVWFNEQELGEAGLYGALAGERGVPVAVASGDDVFIKETKPLLPHTTFVETKQAEGHN
EEEEEECHHHHCCCCCEEECCCCCCCEEEEECCCEEEEECCCCCCCCCCEEECCCCCCCC
AGTSLSPEQSCEAIYAAVKATVQRGHFSMPLRLQAPIVCRLQTQTPALADLFCQWPALER
CCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEECCCEEEEEECCCCHHHHHHHCCCCHHH
VDGTMLRFAADSVEHAVRMLNSLSAMSAMLR
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure
MRILISADIEGVANVFHPEQTRAGNGEYERARRWMTAEADAAVRGAFDGGATDVLVNDSH
CEEEEECCCHHHHHHCCCCCCCCCCCHHHHHHHHCCCCCCHHEEECCCCCCEEEEEECCC
GGFRNLIPDSIDRRARFVLGKPRYLSMMAGVDGCDAVCMIGYHARAGSRGVLAHTINSFA
CCHHHCCCHHHHHHHHEEECCCHHHHHHCCCCCCCEEEEEEEECCCCCCCHHHHHHHHHE
FARVWFNEQELGEAGLYGALAGERGVPVAVASGDDVFIKETKPLLPHTTFVETKQAEGHN
EEEEEECHHHHCCCCCEEECCCCCCCEEEEECCCEEEEECCCCCCCCCCEEECCCCCCCC
AGTSLSPEQSCEAIYAAVKATVQRGHFSMPLRLQAPIVCRLQTQTPALADLFCQWPALER
CCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEECCCEEEEEECCCCHHHHHHHCCCCHHH
VDGTMLRFAADSVEHAVRMLNSLSAMSAMLR
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1766370; 9384377 [H]