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The map label for this gene is hexR [H]

Identifier: 187928339

GI number: 187928339

Start: 1339070

End: 1340059

Strand: Direct

Name: hexR [H]

Synonym: Rpic_1250

Alternate gene names: 187928339

Gene position: 1339070-1340059 (Clockwise)

Preceding gene: 187928336

Following gene: 187928340

Centisome position: 33.96

GC content: 67.78

Gene sequence:

>990_bases
ATGGCGAAATCCACCAGCAAGCGTACGGATGTGTCGAAAGGCGCATTTGCCGCCGATGCGACGGTCTCCGAGCGCATTGG
GGCGGCCCTTGCCACGCTCACGCCCGCGCACCAGCGCATGGCGGAATACGTGCTGGCGAACCCGTTCCGCGCCGCCACCA
TGCGCATCGACGAGTTTGCCGCGGCGGTCGACATGTCGATTGCCACGGCCAACCGGTTCGCGCTGGCGCTGGGCTTTGAC
GGCTATCCGCAGTTCCGTGCCGGGCTGCTGCGCGGTTTCGAAGCGACGCTCGCGCCAGTGGAAAAGCTGCGCCACGAGCT
GGCACGCCCGGCTACCAGCGCGGAGATCTTTGCCGCCTCGCTCAACGAAGACATCGCCAACCTTGATGCCACGCGCCGCA
TGCTCGACCCCGCAGCCTGCGAACGCGCGGTCGACGCCATCCTGGGCGCACAGCGCATCTACGTGATGGGCTTTGGCGCC
AGCGGTTATCTGGCGGGGCTGCTGCGCCATGGGCTCGATCTGTACTGCGACACGGTGATCTCCGTTTCGCAGCCGGGCGG
CGCATCGGATGCGGCACGCCAACTGCGCAAGATCGGGCCGAAGGATCTGCTGATCGCCATCGCTTTCCCGCGCTATGCGG
CGGACACCATCACGCTGGCCAAGCAGGCCGGTAAGCAAGGCTGCCAACTGCTGGCGCTGACCGACAGCCCCACATCGCCG
CTCGCGCCGCTGGCCGACATTGCGCTGTATGCGCGGCCGGAGCGGCAATTCTCCGCCACGTCCGACACGGCCGCCGTGGC
GCTGTTCGAAGCGCTGTGCGGCGCGGTGGCGCATCGTTCGGCGCATTCGCTGGAATCGGCCGAACGCCTGACTGAATTCG
TGCTGCCGTGGCTGCATACAGCCCCAGCGCCGCGCACCAATGACGCCCCGGGCGCCTCCGGCACACCGACAACCACCCGA
CGCGGCCGCAAACGCGCCGCTGAAAACTGA

Upstream 100 bases:

>100_bases
ATTCGACCTAGGGAAAACCATAGGTCTTCATGAAAGTTTTTTTCTTTACACGGTCGATTCGTGAAAATACATTTACACAA
AATTTTCACGGCCCAGGAAC

Downstream 100 bases:

>100_bases
TTGACATCGAGCCACGCATGACTACGCCCATCCTCGCCATCCACGGCGGCGCCGGCACCATCACCCGCACGGCCATGAGT
GCCGACAAGGAAGCCGCTTA

Product: RpiR family transcriptional regulator

Products: NA

Alternate protein names: Hex regulon repressor [H]

Number of amino acids: Translated: 329; Mature: 328

Protein sequence:

>329_residues
MAKSTSKRTDVSKGAFAADATVSERIGAALATLTPAHQRMAEYVLANPFRAATMRIDEFAAAVDMSIATANRFALALGFD
GYPQFRAGLLRGFEATLAPVEKLRHELARPATSAEIFAASLNEDIANLDATRRMLDPAACERAVDAILGAQRIYVMGFGA
SGYLAGLLRHGLDLYCDTVISVSQPGGASDAARQLRKIGPKDLLIAIAFPRYAADTITLAKQAGKQGCQLLALTDSPTSP
LAPLADIALYARPERQFSATSDTAAVALFEALCGAVAHRSAHSLESAERLTEFVLPWLHTAPAPRTNDAPGASGTPTTTR
RGRKRAAEN

Sequences:

>Translated_329_residues
MAKSTSKRTDVSKGAFAADATVSERIGAALATLTPAHQRMAEYVLANPFRAATMRIDEFAAAVDMSIATANRFALALGFD
GYPQFRAGLLRGFEATLAPVEKLRHELARPATSAEIFAASLNEDIANLDATRRMLDPAACERAVDAILGAQRIYVMGFGA
SGYLAGLLRHGLDLYCDTVISVSQPGGASDAARQLRKIGPKDLLIAIAFPRYAADTITLAKQAGKQGCQLLALTDSPTSP
LAPLADIALYARPERQFSATSDTAAVALFEALCGAVAHRSAHSLESAERLTEFVLPWLHTAPAPRTNDAPGASGTPTTTR
RGRKRAAEN
>Mature_328_residues
AKSTSKRTDVSKGAFAADATVSERIGAALATLTPAHQRMAEYVLANPFRAATMRIDEFAAAVDMSIATANRFALALGFDG
YPQFRAGLLRGFEATLAPVEKLRHELARPATSAEIFAASLNEDIANLDATRRMLDPAACERAVDAILGAQRIYVMGFGAS
GYLAGLLRHGLDLYCDTVISVSQPGGASDAARQLRKIGPKDLLIAIAFPRYAADTITLAKQAGKQGCQLLALTDSPTSPL
APLADIALYARPERQFSATSDTAAVALFEALCGAVAHRSAHSLESAERLTEFVLPWLHTAPAPRTNDAPGASGTPTTTRR
GRKRAAEN

Specific function: Represses the expression of the hex regulon (zwf, eda, glp and gap) [H]

COG id: COG1737

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SIS domain [H]

Homologues:

Organism=Escherichia coli, GI1788159, Length=234, Percent_Identity=25.6410256410256, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000281
- InterPro:   IPR001347
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01418 HTH_6; PF01380 SIS [H]

EC number: NA

Molecular weight: Translated: 34839; Mature: 34708

Theoretical pI: Translated: 8.61; Mature: 8.61

Prosite motif: PS51071 HTH_RPIR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKSTSKRTDVSKGAFAADATVSERIGAALATLTPAHQRMAEYVLANPFRAATMRIDEFA
CCCCCCCCCCCCCCCCHHCCHHHHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHHH
AAVDMSIATANRFALALGFDGYPQFRAGLLRGFEATLAPVEKLRHELARPATSAEIFAAS
HHHHHHHHHHCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
LNEDIANLDATRRMLDPAACERAVDAILGAQRIYVMGFGASGYLAGLLRHGLDLYCDTVI
HHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCEEEEEEECCHHHHHHHHHCCHHHHHHHHH
SVSQPGGASDAARQLRKIGPKDLLIAIAFPRYAADTITLAKQAGKQGCQLLALTDSPTSP
EECCCCCCHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHCCCCCEEEEEECCCCCC
LAPLADIALYARPERQFSATSDTAAVALFEALCGAVAHRSAHSLESAERLTEFVLPWLHT
CCHHHHHHHHCCCCHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
APAPRTNDAPGASGTPTTTRRGRKRAAEN
CCCCCCCCCCCCCCCCCCHHHHHHHCCCC
>Mature Secondary Structure 
AKSTSKRTDVSKGAFAADATVSERIGAALATLTPAHQRMAEYVLANPFRAATMRIDEFA
CCCCCCCCCCCCCCCHHCCHHHHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHHH
AAVDMSIATANRFALALGFDGYPQFRAGLLRGFEATLAPVEKLRHELARPATSAEIFAAS
HHHHHHHHHHCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
LNEDIANLDATRRMLDPAACERAVDAILGAQRIYVMGFGASGYLAGLLRHGLDLYCDTVI
HHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCEEEEEEECCHHHHHHHHHCCHHHHHHHHH
SVSQPGGASDAARQLRKIGPKDLLIAIAFPRYAADTITLAKQAGKQGCQLLALTDSPTSP
EECCCCCCHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHCCCCCEEEEEECCCCCC
LAPLADIALYARPERQFSATSDTAAVALFEALCGAVAHRSAHSLESAERLTEFVLPWLHT
CCHHHHHHHHCCCCHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
APAPRTNDAPGASGTPTTTRRGRKRAAEN
CCCCCCCCCCCCCCCCCCHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]