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The map label for this gene is yheS [H]

Identifier: 187928338

GI number: 187928338

Start: 1336892

End: 1338829

Strand: Reverse

Name: yheS [H]

Synonym: Rpic_1249

Alternate gene names: 187928338

Gene position: 1338829-1336892 (Counterclockwise)

Preceding gene: 187928348

Following gene: 187928337

Centisome position: 33.96

GC content: 65.58

Gene sequence:

>1938_bases
GTGATCCGATTCGACGACCTCGTCCTCCAGCGCGGCACCAAGGTGCTGTTCGACCACGCTACCGCCACTCTCAACCCCGG
TGAACGGGTCGGCCTTGTCGGCGTGAACGGCAGCGGCAAATCCACGTTGTTTTCGATGCTGCGCGGCGAGCTGCACGCCG
ACGGCGGCGAAGTCGCCATCCCGCCCACCTGGCAGGTCGCACACGTGGCGCAGGAAACGCCCGCAGTCGACCGCAGCGCG
CTCGACTACACGCTCGACGGCGATACCCGCCTGCGCGACATCGAACGCCGCCTCGCCGCGGCCGAAGCCGCGCACGACGG
CCACGCGCAAGCCGAAGCCCACACGGCCTTTGCCGATGCCGACGGCTACACCGCCCCGGCGCGCGCGCAAGCGCTGCTGC
TCGGTCTCGGCTTCACAATGGCGCAGACGACGCAACCGGTGGCGAGCTTCTCTGGCGGCTGGCGCATGCGTCTGAATCTG
GCCCAGGCTCTGATGTGCCCGTCCGACCTGCTGCTGCTCGACGAGCCCACCAACCACCTGGATTTGGACGCCGTGGTCTG
GCTGGAAGACTGGCTGTCGCGCTATGCAGGCACGCTGGTGATGATTTCCCACGACCGCGAATTTCTCGACGGCGTGTGCA
ACGTCACGCTGCATATCGAGAACCAGAAGCTCAAACGCTACGGCGGCAACTACACGCAATTCGAAACGCAGCGCCTGCAG
CAGATGGCGCTGCAGGAAGCGTCGTACGCACGGCAGCAGAAGCAGATCGCGCATCTCGAATCGTTCATCACGCGCTTCAA
GGCCAAGGCCAGCAAGGCCAAGCAGGCGCAGAGCCGCGTCAAGGCGCTGGAGCGCATGGAGCGCCTCGCGCCCGTGCATG
CGGCGGCAGGCTTCTCGTTCGAATTCCGCGAGCCTGAGGCGGCGCCCAACCCGATGCTCACGTTTGAAGGCGTCGATTGC
GGCTATCCGGGGCCCACCGAAGACCAGCCGATCACCATCCTCAAACACCTGACGTTCTCGATCCAGACCGGCCAGCGCAT
CGGCCTGCTGGGTGCCAACGGCCAGGGCAAGTCGACGCTGGTGAAAACGCTGGCCGAGACGCTGGCGCCGCTGTCCGGCA
CGATCCGGCGCGGCAAGGGCCTGCAGATCGGCTACTTCGCCCAACACCAGTTGGAAACATTAGATGACCACGCCTCGCCG
CTGCTGCATCTGGCGCGGCTGGCGCCCGACGTACGCGAACAGGAGCTGCGCGACTTTCTCGGCAGCTTCAACTTCCGCGG
CGACATGGCGACCTCGCCCATCGAGCCGTTCTCGGGCGGCGAGAAGGCGCGCCTGGCGCTCGCCCTGATCGTCTGGCAGC
GCCCCAACCTGCTGCTGCTTGATGAACCGACCAACCATCTGGATCTCGACACGCGTGAAGCGTTGACGATGGCGCTCGCC
CAGTTCGACGGCACGCTGATCCTCGTCTCGCACGACCGGCATCTGCTGCGCGCCACGACCGACCAGTTCCTGCTCGTTGG
CCAGGGCACTGTCGCCCCGTTCGACGGCGATCTGGACGACTACCGCGACTGGCTGCTCAAGCAAGCCGCGGCCAAGCGCG
CAGCCGCCGGCGCACAGGCTGCTCCGGCCGATGCGGATGGCGCGCCGGCCACCAACCGCCGCGATCAGAAGCGCGAAGAA
GCCACCGAACGTCAGCGCCTGAATGCGCTACGCAAGCCGCTGCAAAAGAACGTCGATGCCATTGAAAAACGCATGGCACC
GTTGCAGAAGGAAAAGGCGGAACTCGAAGCCTTCCTCGCCGACGGGGTAGCGTATGAGGAAGCCAACAAGGCGCGCATGA
TGGAAAGCCTGCGCCGCCAGGCCGAACTGAACGCCGAACTCGACGAGCTGGAAGAACGCTGGCTCGAGCTGCACGAACAA
CTCGAACAAATCAATTGA

Upstream 100 bases:

>100_bases
TGCAATACACCAGTCCAAACGCCCCAGGTGCGCCAGGATCGTGCGACGCAGCACGCTACAATCGCACCCTTCTCCGATTT
GCCTTCAAGCGCAGTTTTTC

Downstream 100 bases:

>100_bases
GGCTGGCGCGTCCGGCCAAGGAGACCTGTTGATGACATCGCCCTCGCCGGACACCGCCACGCACCAGCCATTGGCCGGCG
TGCGCGTGCTCGACCTGACG

Product: ABC transporter-like protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 645; Mature: 645

Protein sequence:

>645_residues
MIRFDDLVLQRGTKVLFDHATATLNPGERVGLVGVNGSGKSTLFSMLRGELHADGGEVAIPPTWQVAHVAQETPAVDRSA
LDYTLDGDTRLRDIERRLAAAEAAHDGHAQAEAHTAFADADGYTAPARAQALLLGLGFTMAQTTQPVASFSGGWRMRLNL
AQALMCPSDLLLLDEPTNHLDLDAVVWLEDWLSRYAGTLVMISHDREFLDGVCNVTLHIENQKLKRYGGNYTQFETQRLQ
QMALQEASYARQQKQIAHLESFITRFKAKASKAKQAQSRVKALERMERLAPVHAAAGFSFEFREPEAAPNPMLTFEGVDC
GYPGPTEDQPITILKHLTFSIQTGQRIGLLGANGQGKSTLVKTLAETLAPLSGTIRRGKGLQIGYFAQHQLETLDDHASP
LLHLARLAPDVREQELRDFLGSFNFRGDMATSPIEPFSGGEKARLALALIVWQRPNLLLLDEPTNHLDLDTREALTMALA
QFDGTLILVSHDRHLLRATTDQFLLVGQGTVAPFDGDLDDYRDWLLKQAAAKRAAAGAQAAPADADGAPATNRRDQKREE
ATERQRLNALRKPLQKNVDAIEKRMAPLQKEKAELEAFLADGVAYEEANKARMMESLRRQAELNAELDELEERWLELHEQ
LEQIN

Sequences:

>Translated_645_residues
MIRFDDLVLQRGTKVLFDHATATLNPGERVGLVGVNGSGKSTLFSMLRGELHADGGEVAIPPTWQVAHVAQETPAVDRSA
LDYTLDGDTRLRDIERRLAAAEAAHDGHAQAEAHTAFADADGYTAPARAQALLLGLGFTMAQTTQPVASFSGGWRMRLNL
AQALMCPSDLLLLDEPTNHLDLDAVVWLEDWLSRYAGTLVMISHDREFLDGVCNVTLHIENQKLKRYGGNYTQFETQRLQ
QMALQEASYARQQKQIAHLESFITRFKAKASKAKQAQSRVKALERMERLAPVHAAAGFSFEFREPEAAPNPMLTFEGVDC
GYPGPTEDQPITILKHLTFSIQTGQRIGLLGANGQGKSTLVKTLAETLAPLSGTIRRGKGLQIGYFAQHQLETLDDHASP
LLHLARLAPDVREQELRDFLGSFNFRGDMATSPIEPFSGGEKARLALALIVWQRPNLLLLDEPTNHLDLDTREALTMALA
QFDGTLILVSHDRHLLRATTDQFLLVGQGTVAPFDGDLDDYRDWLLKQAAAKRAAAGAQAAPADADGAPATNRRDQKREE
ATERQRLNALRKPLQKNVDAIEKRMAPLQKEKAELEAFLADGVAYEEANKARMMESLRRQAELNAELDELEERWLELHEQ
LEQIN
>Mature_645_residues
MIRFDDLVLQRGTKVLFDHATATLNPGERVGLVGVNGSGKSTLFSMLRGELHADGGEVAIPPTWQVAHVAQETPAVDRSA
LDYTLDGDTRLRDIERRLAAAEAAHDGHAQAEAHTAFADADGYTAPARAQALLLGLGFTMAQTTQPVASFSGGWRMRLNL
AQALMCPSDLLLLDEPTNHLDLDAVVWLEDWLSRYAGTLVMISHDREFLDGVCNVTLHIENQKLKRYGGNYTQFETQRLQ
QMALQEASYARQQKQIAHLESFITRFKAKASKAKQAQSRVKALERMERLAPVHAAAGFSFEFREPEAAPNPMLTFEGVDC
GYPGPTEDQPITILKHLTFSIQTGQRIGLLGANGQGKSTLVKTLAETLAPLSGTIRRGKGLQIGYFAQHQLETLDDHASP
LLHLARLAPDVREQELRDFLGSFNFRGDMATSPIEPFSGGEKARLALALIVWQRPNLLLLDEPTNHLDLDTREALTMALA
QFDGTLILVSHDRHLLRATTDQFLLVGQGTVAPFDGDLDDYRDWLLKQAAAKRAAAGAQAAPADADGAPATNRRDQKREE
ATERQRLNALRKPLQKNVDAIEKRMAPLQKEKAELEAFLADGVAYEEANKARMMESLRRQAELNAELDELEERWLELHEQ
LEQIN

Specific function: Unknown

COG id: COG0488

COG function: function code R; ATPase components of ABC transporters with duplicated ATPase domains

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 ABC transporter domains [H]

Homologues:

Organism=Homo sapiens, GI148612853, Length=536, Percent_Identity=38.2462686567164, Blast_Score=352, Evalue=8e-97,
Organism=Homo sapiens, GI10947137, Length=516, Percent_Identity=38.953488372093, Blast_Score=347, Evalue=2e-95,
Organism=Homo sapiens, GI27881506, Length=516, Percent_Identity=38.953488372093, Blast_Score=347, Evalue=3e-95,
Organism=Homo sapiens, GI10947135, Length=549, Percent_Identity=34.608378870674, Blast_Score=268, Evalue=1e-71,
Organism=Homo sapiens, GI69354671, Length=549, Percent_Identity=34.608378870674, Blast_Score=267, Evalue=2e-71,
Organism=Escherichia coli, GI1789751, Length=644, Percent_Identity=54.1925465838509, Blast_Score=682, Evalue=0.0,
Organism=Escherichia coli, GI1787041, Length=531, Percent_Identity=35.7815442561205, Blast_Score=334, Evalue=1e-92,
Organism=Escherichia coli, GI1787182, Length=534, Percent_Identity=31.4606741573034, Blast_Score=229, Evalue=5e-61,
Organism=Escherichia coli, GI2367384, Length=529, Percent_Identity=30.6238185255198, Blast_Score=204, Evalue=2e-53,
Organism=Escherichia coli, GI1788165, Length=182, Percent_Identity=34.0659340659341, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1788506, Length=206, Percent_Identity=25.2427184466019, Blast_Score=66, Evalue=6e-12,
Organism=Escherichia coli, GI1787758, Length=219, Percent_Identity=25.5707762557078, Blast_Score=64, Evalue=3e-11,
Organism=Escherichia coli, GI87081782, Length=164, Percent_Identity=31.0975609756098, Blast_Score=62, Evalue=8e-11,
Organism=Caenorhabditis elegans, GI17553372, Length=539, Percent_Identity=38.0333951762523, Blast_Score=344, Evalue=8e-95,
Organism=Caenorhabditis elegans, GI17555318, Length=525, Percent_Identity=36, Blast_Score=332, Evalue=3e-91,
Organism=Caenorhabditis elegans, GI17559834, Length=556, Percent_Identity=33.9928057553957, Blast_Score=309, Evalue=3e-84,
Organism=Caenorhabditis elegans, GI25146777, Length=223, Percent_Identity=29.5964125560538, Blast_Score=77, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17569145, Length=233, Percent_Identity=27.8969957081545, Blast_Score=69, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI17532409, Length=215, Percent_Identity=25.1162790697674, Blast_Score=65, Evalue=8e-11,
Organism=Saccharomyces cerevisiae, GI6321121, Length=554, Percent_Identity=35.3790613718412, Blast_Score=341, Evalue=2e-94,
Organism=Saccharomyces cerevisiae, GI6320874, Length=539, Percent_Identity=35.0649350649351, Blast_Score=306, Evalue=6e-84,
Organism=Saccharomyces cerevisiae, GI6325030, Length=394, Percent_Identity=30.9644670050761, Blast_Score=159, Evalue=2e-39,
Organism=Saccharomyces cerevisiae, GI6324314, Length=397, Percent_Identity=29.4710327455919, Blast_Score=158, Evalue=3e-39,
Organism=Saccharomyces cerevisiae, GI6323278, Length=403, Percent_Identity=27.7915632754342, Blast_Score=149, Evalue=1e-36,
Organism=Drosophila melanogaster, GI24666836, Length=538, Percent_Identity=39.0334572490706, Blast_Score=375, Evalue=1e-104,
Organism=Drosophila melanogaster, GI24642252, Length=537, Percent_Identity=38.7337057728119, Blast_Score=364, Evalue=1e-100,
Organism=Drosophila melanogaster, GI18859989, Length=537, Percent_Identity=38.7337057728119, Blast_Score=364, Evalue=1e-100,
Organism=Drosophila melanogaster, GI24641342, Length=545, Percent_Identity=34.8623853211009, Blast_Score=312, Evalue=4e-85,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 71431; Mature: 71431

Theoretical pI: Translated: 5.62; Mature: 5.62

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRFDDLVLQRGTKVLFDHATATLNPGERVGLVGVNGSGKSTLFSMLRGELHADGGEVAI
CCCCHHHHHHCCCEEEEECCCEECCCCCEEEEEEECCCCHHHHHHHHHHHHCCCCCCEEC
PPTWQVAHVAQETPAVDRSALDYTLDGDTRLRDIERRLAAAEAAHDGHAQAEAHTAFADA
CCCCHHHHHHHHCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHEECC
DGYTAPARAQALLLGLGFTMAQTTQPVASFSGGWRMRLNLAQALMCPSDLLLLDEPTNHL
CCCCCCHHHHHHHHHHCHHHHHHCCHHHHCCCCCEEEHHHHHHHHCCCCEEEEECCCCCC
DLDAVVWLEDWLSRYAGTLVMISHDREFLDGVCNVTLHIENQKLKRYGGNYTQFETQRLQ
CCHHHHHHHHHHHHHCCEEEEEECCHHHHHHHCEEEEEECCHHHHHHCCCCCHHHHHHHH
QMALQEASYARQQKQIAHLESFITRFKAKASKAKQAQSRVKALERMERLAPVHAAAGFSF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCE
EFREPEAAPNPMLTFEGVDCGYPGPTEDQPITILKHLTFSIQTGQRIGLLGANGQGKSTL
ECCCCCCCCCCCEEECCCCCCCCCCCCCCCCHHHHHHEEEEECCCEEEEEECCCCCHHHH
VKTLAETLAPLSGTIRRGKGLQIGYFAQHQLETLDDHASPLLHLARLAPDVREQELRDFL
HHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
GSFNFRGDMATSPIEPFSGGEKARLALALIVWQRPNLLLLDEPTNHLDLDTREALTMALA
HCCCCCCCCCCCCCCCCCCCCHHHEEEEEEEECCCCEEEEECCCCCCCCCHHHHHHHHHH
QFDGTLILVSHDRHLLRATTDQFLLVGQGTVAPFDGDLDDYRDWLLKQAAAKRAAAGAQA
HCCCEEEEEECCCHHHHHCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCC
APADADGAPATNRRDQKREEATERQRLNALRKPLQKNVDAIEKRMAPLQKEKAELEAFLA
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DGVAYEEANKARMMESLRRQAELNAELDELEERWLELHEQLEQIN
CCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MIRFDDLVLQRGTKVLFDHATATLNPGERVGLVGVNGSGKSTLFSMLRGELHADGGEVAI
CCCCHHHHHHCCCEEEEECCCEECCCCCEEEEEEECCCCHHHHHHHHHHHHCCCCCCEEC
PPTWQVAHVAQETPAVDRSALDYTLDGDTRLRDIERRLAAAEAAHDGHAQAEAHTAFADA
CCCCHHHHHHHHCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHEECC
DGYTAPARAQALLLGLGFTMAQTTQPVASFSGGWRMRLNLAQALMCPSDLLLLDEPTNHL
CCCCCCHHHHHHHHHHCHHHHHHCCHHHHCCCCCEEEHHHHHHHHCCCCEEEEECCCCCC
DLDAVVWLEDWLSRYAGTLVMISHDREFLDGVCNVTLHIENQKLKRYGGNYTQFETQRLQ
CCHHHHHHHHHHHHHCCEEEEEECCHHHHHHHCEEEEEECCHHHHHHCCCCCHHHHHHHH
QMALQEASYARQQKQIAHLESFITRFKAKASKAKQAQSRVKALERMERLAPVHAAAGFSF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCE
EFREPEAAPNPMLTFEGVDCGYPGPTEDQPITILKHLTFSIQTGQRIGLLGANGQGKSTL
ECCCCCCCCCCCEEECCCCCCCCCCCCCCCCHHHHHHEEEEECCCEEEEEECCCCCHHHH
VKTLAETLAPLSGTIRRGKGLQIGYFAQHQLETLDDHASPLLHLARLAPDVREQELRDFL
HHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
GSFNFRGDMATSPIEPFSGGEKARLALALIVWQRPNLLLLDEPTNHLDLDTREALTMALA
HCCCCCCCCCCCCCCCCCCCCHHHEEEEEEEECCCCEEEEECCCCCCCCCHHHHHHHHHH
QFDGTLILVSHDRHLLRATTDQFLLVGQGTVAPFDGDLDDYRDWLLKQAAAKRAAAGAQA
HCCCEEEEEECCCHHHHHCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCC
APADADGAPATNRRDQKREEATERQRLNALRKPLQKNVDAIEKRMAPLQKEKAELEAFLA
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DGVAYEEANKARMMESLRRQAELNAELDELEERWLELHEQLEQIN
CCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]