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The map label for this gene is pepV [H]

Identifier: 187928265

GI number: 187928265

Start: 1265354

End: 1267084

Strand: Direct

Name: pepV [H]

Synonym: Rpic_1176

Alternate gene names: 187928265

Gene position: 1265354-1267084 (Clockwise)

Preceding gene: 187928263

Following gene: 187928266

Centisome position: 32.09

GC content: 63.26

Gene sequence:

>1731_bases
ATGCAACGCACTGCCCGTATTGGCCTGTCTTCGCTGACGATCGCACTGTCGCTGGCTTGCGGCACCGGCGCCTTTGCCGC
CACGATTCAGAAACCGCAACTCGACGCGCTGCTCGCCGCCGAGCAATCCAAGGCATCGGCCGATCTGAACAGCTTTCTTG
CGGCAGCCGCGAAGGCCGATCCGCAAGTCGCGGGCAGTGTCGCCGCGTACCAGAAGAAGGCTCCGGTGGCCGGCGATGAC
CTCGTCAACATCGGGCGCCTGCTGGGTCTGTACAACCGCCTGCACAACCAGCAGGCCGTGATTGGTTCGATCGAAAAGAT
GGTCGCGCTGCCCACGGTGCGCGACGACAAGATTCCGCAGTACGAAAACCCCGCCATCGTCGCGTTTGGCAAGCTGATCG
AGGGCATGGCGCGCGATTTCGGCTTGAAATACCGCAACGTCGACAACCGCGTCTTTGAAGTTACGCTGCCCGGCACCGGC
TCGGACGAGTTCGGCATCCTGACGCACGCCGACGTCGTACCCGCCAAGGCCGAGGAGTGGGTGCTCGGCGACGGCACCAA
GCTCGATCCGTTCAAGGTCACGCGCGTCGGCAATCTGCTGTACGGCCGTGGCACGATTGACGACAAGGGCTCGATTGCCG
CCGCGATGTACGCCATGAAAACGGTCAAGGACAGTGGCGTGCCGCTCGCGCGCACCATCCGCCTGATGATCGAAACCACC
GAAGAAACCGGTGGCGATGGCATGAAGTACTACCGTGAGCACACGCAATTGCCTGCGTACAACATCGTGCTCGACAGCAA
GTACCCGGCCGTGGTTGCAGAGAAAGGCTCGGGCGCATTGAAGGTGTTCTTCCCTGCGCAAGCTGGCGATGCTTCGCATA
CGGCCATCGTTTCGATGACGGGCGCGGCGTCGGCAAGCTCCATCCCACAAACGGCCACCGCCACGCTCAAGGGCGGTGAT
CTGGGCCTGGCCGCCGCCGCGCTCGAAGCCAAGCGCGATGGGTTCGTGAACAGCTTGGCAGGGCAGGGCAAGTTCTCGAT
CGACATCGCGCGCACGGGCGACAGCATCGTCGTGAAGGTGACTGGCGCCTCCGCACACGGCTCGCGTCCGGAAGAGGGCG
TCAACCCGCTGCCGCGCCTCGCGCTGTTCCTGCGTGCAGCCGATCTCGGCTTGGCAGACAACGCCTACGCTCATGCCGTG
CGCTACCTCACCGACCTTTACGGCACCGACTACCTCGGCACTACCATGGGCGTCGCCTACAAGGACGACTTCATGGGGCC
GCTCACCATTTCGCCTACGGTGATCGGCGACAAGAATGGCCGCGTGGAGGTGAGCGCCAACGTGCGCATGCCGCGCGGCA
AAACGCCTGATGCGCTGCGCGGTGAAATCGCCGGCAAGATCAACGCATGGGCCAAGGCCAACCATGTCGCCCTCGAGATC
AACCACGATCAAGGCAACTGGATGGCGCGCGATCCGAAGGGCGCGTGGCTGTCGACGCTGCTCAACATTTATGGTGACAC
CACGGGCCTCGACGCCAAGCCCGTGCCGACGGCCGGCAGCACGACGGCCAAGCTGATGCCGAACGCCATCAATTTCGGCC
CGGCCATGCCGGGCAAGAAGTACACGGCGCACAACGCCAACGAGTACAAGGAAGTGCAGGACCTCGACCTCGATATGCAG
ATGTTCACCGAGATGTTGGTGCGCATCGGCAACCTGCAGTCAATGCAATAA

Upstream 100 bases:

>100_bases
ACCGCGCAGCGGGCGTGCCTTAGCGTTTTCGCGCTGCACAATGCGTGGCTTGCGCTTCGCCCCTATGATGGCGCCTTCGC
CTTTTTCGGAAACCACTTCG

Downstream 100 bases:

>100_bases
CCGACGCACGATCGCCATGAACATCATCCGCGCCAAGTCGTTCACCGCCGAGCGTGCCTGGGGCGCGCTCGATATTGCCA
ATATGAGTGGCATTACCACG

Product: hypothetical protein

Products: NA

Alternate protein names: Beta-Ala-His dipeptidase; Peptidase V [H]

Number of amino acids: Translated: 576; Mature: 576

Protein sequence:

>576_residues
MQRTARIGLSSLTIALSLACGTGAFAATIQKPQLDALLAAEQSKASADLNSFLAAAAKADPQVAGSVAAYQKKAPVAGDD
LVNIGRLLGLYNRLHNQQAVIGSIEKMVALPTVRDDKIPQYENPAIVAFGKLIEGMARDFGLKYRNVDNRVFEVTLPGTG
SDEFGILTHADVVPAKAEEWVLGDGTKLDPFKVTRVGNLLYGRGTIDDKGSIAAAMYAMKTVKDSGVPLARTIRLMIETT
EETGGDGMKYYREHTQLPAYNIVLDSKYPAVVAEKGSGALKVFFPAQAGDASHTAIVSMTGAASASSIPQTATATLKGGD
LGLAAAALEAKRDGFVNSLAGQGKFSIDIARTGDSIVVKVTGASAHGSRPEEGVNPLPRLALFLRAADLGLADNAYAHAV
RYLTDLYGTDYLGTTMGVAYKDDFMGPLTISPTVIGDKNGRVEVSANVRMPRGKTPDALRGEIAGKINAWAKANHVALEI
NHDQGNWMARDPKGAWLSTLLNIYGDTTGLDAKPVPTAGSTTAKLMPNAINFGPAMPGKKYTAHNANEYKEVQDLDLDMQ
MFTEMLVRIGNLQSMQ

Sequences:

>Translated_576_residues
MQRTARIGLSSLTIALSLACGTGAFAATIQKPQLDALLAAEQSKASADLNSFLAAAAKADPQVAGSVAAYQKKAPVAGDD
LVNIGRLLGLYNRLHNQQAVIGSIEKMVALPTVRDDKIPQYENPAIVAFGKLIEGMARDFGLKYRNVDNRVFEVTLPGTG
SDEFGILTHADVVPAKAEEWVLGDGTKLDPFKVTRVGNLLYGRGTIDDKGSIAAAMYAMKTVKDSGVPLARTIRLMIETT
EETGGDGMKYYREHTQLPAYNIVLDSKYPAVVAEKGSGALKVFFPAQAGDASHTAIVSMTGAASASSIPQTATATLKGGD
LGLAAAALEAKRDGFVNSLAGQGKFSIDIARTGDSIVVKVTGASAHGSRPEEGVNPLPRLALFLRAADLGLADNAYAHAV
RYLTDLYGTDYLGTTMGVAYKDDFMGPLTISPTVIGDKNGRVEVSANVRMPRGKTPDALRGEIAGKINAWAKANHVALEI
NHDQGNWMARDPKGAWLSTLLNIYGDTTGLDAKPVPTAGSTTAKLMPNAINFGPAMPGKKYTAHNANEYKEVQDLDLDMQ
MFTEMLVRIGNLQSMQ
>Mature_576_residues
MQRTARIGLSSLTIALSLACGTGAFAATIQKPQLDALLAAEQSKASADLNSFLAAAAKADPQVAGSVAAYQKKAPVAGDD
LVNIGRLLGLYNRLHNQQAVIGSIEKMVALPTVRDDKIPQYENPAIVAFGKLIEGMARDFGLKYRNVDNRVFEVTLPGTG
SDEFGILTHADVVPAKAEEWVLGDGTKLDPFKVTRVGNLLYGRGTIDDKGSIAAAMYAMKTVKDSGVPLARTIRLMIETT
EETGGDGMKYYREHTQLPAYNIVLDSKYPAVVAEKGSGALKVFFPAQAGDASHTAIVSMTGAASASSIPQTATATLKGGD
LGLAAAALEAKRDGFVNSLAGQGKFSIDIARTGDSIVVKVTGASAHGSRPEEGVNPLPRLALFLRAADLGLADNAYAHAV
RYLTDLYGTDYLGTTMGVAYKDDFMGPLTISPTVIGDKNGRVEVSANVRMPRGKTPDALRGEIAGKINAWAKANHVALEI
NHDQGNWMARDPKGAWLSTLLNIYGDTTGLDAKPVPTAGSTTAKLMPNAINFGPAMPGKKYTAHNANEYKEVQDLDLDMQ
MFTEMLVRIGNLQSMQ

Specific function: Is a relatively unspecific dipeptidase cleaving a variety of dipeptides, notably those with an N-terminal beta-Ala or D-Ala residue, e.g. carnosine (beta-Ala-His). To a lesser extent, also shows aminopeptidase activity, since it is able to catalyze the re

COG id: COG0624

COG function: function code E; Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M20A family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001261
- InterPro:   IPR011291
- InterPro:   IPR010964
- InterPro:   IPR002933
- InterPro:   IPR011650 [H]

Pfam domain/function: PF01546 Peptidase_M20 [H]

EC number: 3.4.13.3

Molecular weight: Translated: 61059; Mature: 61059

Theoretical pI: Translated: 7.34; Mature: 7.34

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQRTARIGLSSLTIALSLACGTGAFAATIQKPQLDALLAAEQSKASADLNSFLAAAAKAD
CCCCHHCCHHEEEEEEEEECCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCC
PQVAGSVAAYQKKAPVAGDDLVNIGRLLGLYNRLHNQQAVIGSIEKMVALPTVRDDKIPQ
CHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCC
YENPAIVAFGKLIEGMARDFGLKYRNVDNRVFEVTLPGTGSDEFGILTHADVVPAKAEEW
CCCCEEEEHHHHHHHHHHHHCCEEECCCCEEEEEEECCCCCCCCCEEEECCCCCCCCCCE
VLGDGTKLDPFKVTRVGNLLYGRGTIDDKGSIAAAMYAMKTVKDSGVPLARTIRLMIETT
EECCCCCCCCEEEEEECCEEEECCCCCCCCCHHHHHHHHHHHHCCCCCHHHEEEEEEEEC
EETGGDGMKYYREHTQLPAYNIVLDSKYPAVVAEKGSGALKVFFPAQAGDASHTAIVSMT
CCCCCCHHHHHHHHCCCCEEEEEECCCCCEEEEECCCCEEEEEEECCCCCCCCEEEEEEE
GAASASSIPQTATATLKGGDLGLAAAALEAKRDGFVNSLAGQGKFSIDIARTGDSIVVKV
CCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHCCHHHHHCCCCEEEEEEEECCCEEEEEE
TGASAHGSRPEEGVNPLPRLALFLRAADLGLADNAYAHAVRYLTDLYGTDYLGTTMGVAY
ECCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCHHHCCCEE
KDDFMGPLTISPTVIGDKNGRVEVSANVRMPRGKTPDALRGEIAGKINAWAKANHVALEI
CCCCCCCEEECCEEEECCCCEEEEEEEEECCCCCCCHHHHHHHCCCEECCCCCCEEEEEE
NHDQGNWMARDPKGAWLSTLLNIYGDTTGLDAKPVPTAGSTTAKLMPNAINFGPAMPGKK
ECCCCCEEEECCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHCCCCCCCCCCCCCCC
YTAHNANEYKEVQDLDLDMQMFTEMLVRIGNLQSMQ
EECCCCHHHHHHHHCCCCHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MQRTARIGLSSLTIALSLACGTGAFAATIQKPQLDALLAAEQSKASADLNSFLAAAAKAD
CCCCHHCCHHEEEEEEEEECCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCC
PQVAGSVAAYQKKAPVAGDDLVNIGRLLGLYNRLHNQQAVIGSIEKMVALPTVRDDKIPQ
CHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCC
YENPAIVAFGKLIEGMARDFGLKYRNVDNRVFEVTLPGTGSDEFGILTHADVVPAKAEEW
CCCCEEEEHHHHHHHHHHHHCCEEECCCCEEEEEEECCCCCCCCCEEEECCCCCCCCCCE
VLGDGTKLDPFKVTRVGNLLYGRGTIDDKGSIAAAMYAMKTVKDSGVPLARTIRLMIETT
EECCCCCCCCEEEEEECCEEEECCCCCCCCCHHHHHHHHHHHHCCCCCHHHEEEEEEEEC
EETGGDGMKYYREHTQLPAYNIVLDSKYPAVVAEKGSGALKVFFPAQAGDASHTAIVSMT
CCCCCCHHHHHHHHCCCCEEEEEECCCCCEEEEECCCCEEEEEEECCCCCCCCEEEEEEE
GAASASSIPQTATATLKGGDLGLAAAALEAKRDGFVNSLAGQGKFSIDIARTGDSIVVKV
CCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHCCHHHHHCCCCEEEEEEEECCCEEEEEE
TGASAHGSRPEEGVNPLPRLALFLRAADLGLADNAYAHAVRYLTDLYGTDYLGTTMGVAY
ECCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCHHHCCCEE
KDDFMGPLTISPTVIGDKNGRVEVSANVRMPRGKTPDALRGEIAGKINAWAKANHVALEI
CCCCCCCEEECCEEEECCCCEEEEEEEEECCCCCCCHHHHHHHCCCEECCCCCCEEEEEE
NHDQGNWMARDPKGAWLSTLLNIYGDTTGLDAKPVPTAGSTTAKLMPNAINFGPAMPGKK
ECCCCCEEEECCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHCCCCCCCCCCCCCCC
YTAHNANEYKEVQDLDLDMQMFTEMLVRIGNLQSMQ
EECCCCHHHHHHHHCCCCHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7528082 [H]