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The map label for this gene is yafC [H]

Identifier: 187928087

GI number: 187928087

Start: 1051507

End: 1052403

Strand: Reverse

Name: yafC [H]

Synonym: Rpic_0994

Alternate gene names: 187928087

Gene position: 1052403-1051507 (Counterclockwise)

Preceding gene: 187928090

Following gene: 187928086

Centisome position: 26.69

GC content: 67.34

Gene sequence:

>897_bases
ATGAAAACCACACTCGAAGAACTGCTCGCCTTCCGCACCGTCGTCGATACGGGCTCCGTCACGGCGGCGGCTGAGCGGCT
CGGCCAGACGGTGTCGGGCGTGAGCCGCGCGTTGCGCCGCCTGGAAGAGAAGCTGGACACCACCCTGCTCTCGCGCACCA
CGCGGCGGCTGTCGCTCACCGACGAGGGCGCGACGTTTCTGGCGCAGGCGCGCAGCATCCTCGCCGCCGTCGACGAGGCC
GAGGAGCAGATCGCCCTGCGCCGCCAGCAGCCTGCCGGCCGCCTGCGTGTCAACGCTGCCATGCCGTTCATGCTGCATGT
GGTGGCGCCGCTGGTGCCGGACTTCCGCGCACGGTATCCGCAGATCGAGCTGGAGCTGAACACCAACGACCTGATCATCG
ATTTGCTGGAAGAAGACACCGACGTGGCGATCCGCATCGGCACGCTGCGCGATTCCACCCTGCGTGCGCGCCTGCTTGGC
ACGCGGCGGCTGCGCGTGCTGGCGAGCCCTGCCTATCTGAAAGCGCACGGGCGGCCCCGCCACGTGGATGAGCTGCAGAA
GCACGCCCTGCTCGGTTTCGTGCAGCCGGAATCGCTAAACCAATGGCCCCTGCGCGGCCCGTACGGCGATCGCCTGCGCA
TCGAGCCCACGCTCAAGGCCTCCAGCGGAGAAACCCTGCGCCAGCTCGCGCTGCAAGGCGCGGGCATCGTCTGCCTGGCT
GATTTCATGACCGCTGAAGACCGCCGCGCGGGCGATCTCATGCAGGTGCTGCAGGACGCCACGGTGGAGGTGCTGCAGCC
GATTCACGCGGTGTACTACCGCAACACGCAGTTGGCTTCGCGGATTGCGTGCTTTCTCGATTTTCTCGAAGCCCGGCTCG
CCGACGATAAGCAGTGA

Upstream 100 bases:

>100_bases
CTGCATTTGCGCCCGTCCAGGGCAAGGCGCCCCGCACGCGACCTTTGCAAATTACGCCACATTAGGCAGAATTCTTTTGA
TTTTGAATTGACAATCGTCG

Downstream 100 bases:

>100_bases
AGCAGCATCGCTGGTATGCAACAATTGCGCGATTCAACACCTTCCGCGCGCGGCCTGATCGGATCACATCCGGCCGCGCG
CTGCGCTTTAGTACTCATGG

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 298; Mature: 298

Protein sequence:

>298_residues
MKTTLEELLAFRTVVDTGSVTAAAERLGQTVSGVSRALRRLEEKLDTTLLSRTTRRLSLTDEGATFLAQARSILAAVDEA
EEQIALRRQQPAGRLRVNAAMPFMLHVVAPLVPDFRARYPQIELELNTNDLIIDLLEEDTDVAIRIGTLRDSTLRARLLG
TRRLRVLASPAYLKAHGRPRHVDELQKHALLGFVQPESLNQWPLRGPYGDRLRIEPTLKASSGETLRQLALQGAGIVCLA
DFMTAEDRRAGDLMQVLQDATVEVLQPIHAVYYRNTQLASRIACFLDFLEARLADDKQ

Sequences:

>Translated_298_residues
MKTTLEELLAFRTVVDTGSVTAAAERLGQTVSGVSRALRRLEEKLDTTLLSRTTRRLSLTDEGATFLAQARSILAAVDEA
EEQIALRRQQPAGRLRVNAAMPFMLHVVAPLVPDFRARYPQIELELNTNDLIIDLLEEDTDVAIRIGTLRDSTLRARLLG
TRRLRVLASPAYLKAHGRPRHVDELQKHALLGFVQPESLNQWPLRGPYGDRLRIEPTLKASSGETLRQLALQGAGIVCLA
DFMTAEDRRAGDLMQVLQDATVEVLQPIHAVYYRNTQLASRIACFLDFLEARLADDKQ
>Mature_298_residues
MKTTLEELLAFRTVVDTGSVTAAAERLGQTVSGVSRALRRLEEKLDTTLLSRTTRRLSLTDEGATFLAQARSILAAVDEA
EEQIALRRQQPAGRLRVNAAMPFMLHVVAPLVPDFRARYPQIELELNTNDLIIDLLEEDTDVAIRIGTLRDSTLRARLLG
TRRLRVLASPAYLKAHGRPRHVDELQKHALLGFVQPESLNQWPLRGPYGDRLRIEPTLKASSGETLRQLALQGAGIVCLA
DFMTAEDRRAGDLMQVLQDATVEVLQPIHAVYYRNTQLASRIACFLDFLEARLADDKQ

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786401, Length=289, Percent_Identity=45.6747404844291, Blast_Score=267, Evalue=7e-73,
Organism=Escherichia coli, GI87081978, Length=297, Percent_Identity=32.6599326599327, Blast_Score=132, Evalue=2e-32,
Organism=Escherichia coli, GI1789639, Length=288, Percent_Identity=29.8611111111111, Blast_Score=124, Evalue=9e-30,
Organism=Escherichia coli, GI145693193, Length=292, Percent_Identity=30.8219178082192, Blast_Score=116, Evalue=2e-27,
Organism=Escherichia coli, GI1787128, Length=299, Percent_Identity=27.4247491638796, Blast_Score=113, Evalue=2e-26,
Organism=Escherichia coli, GI1789440, Length=287, Percent_Identity=28.2229965156794, Blast_Score=113, Evalue=2e-26,
Organism=Escherichia coli, GI1787589, Length=295, Percent_Identity=27.1186440677966, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI1789173, Length=282, Percent_Identity=26.5957446808511, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI87082132, Length=291, Percent_Identity=25.4295532646048, Blast_Score=78, Evalue=5e-16,
Organism=Escherichia coli, GI1786448, Length=296, Percent_Identity=25.6756756756757, Blast_Score=68, Evalue=6e-13,
Organism=Escherichia coli, GI1788481, Length=302, Percent_Identity=22.8476821192053, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI145693105, Length=158, Percent_Identity=28.4810126582279, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1787879, Length=159, Percent_Identity=33.3333333333333, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI157672245, Length=157, Percent_Identity=32.484076433121, Blast_Score=64, Evalue=9e-12,
Organism=Escherichia coli, GI1788748, Length=181, Percent_Identity=27.6243093922652, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1786508, Length=146, Percent_Identity=30.1369863013699, Blast_Score=62, Evalue=6e-11,
Organism=Escherichia coli, GI1787806, Length=153, Percent_Identity=28.7581699346405, Blast_Score=62, Evalue=7e-11,
Organism=Escherichia coli, GI1788706, Length=173, Percent_Identity=26.5895953757225, Blast_Score=61, Evalue=7e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33284; Mature: 33284

Theoretical pI: Translated: 7.63; Mature: 7.63

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTTLEELLAFRTVVDTGSVTAAAERLGQTVSGVSRALRRLEEKLDTTLLSRTTRRLSLT
CCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEC
DEGATFLAQARSILAAVDEAEEQIALRRQQPAGRLRVNAAMPFMLHVVAPLVPDFRARYP
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECHHHHHHHHHHHHHCCHHHCCCC
QIELELNTNDLIIDLLEEDTDVAIRIGTLRDSTLRARLLGTRRLRVLASPAYLKAHGRPR
EEEEEECCCCEEEEEECCCCCEEEEEECCCCHHHHHHHHHHHHHHHHCCCHHEECCCCCC
HVDELQKHALLGFVQPESLNQWPLRGPYGDRLRIEPTLKASSGETLRQLALQGAGIVCLA
CHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHCCCCCEEEH
DFMTAEDRRAGDLMQVLQDATVEVLQPIHAVYYRNTQLASRIACFLDFLEARLADDKQ
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MKTTLEELLAFRTVVDTGSVTAAAERLGQTVSGVSRALRRLEEKLDTTLLSRTTRRLSLT
CCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEC
DEGATFLAQARSILAAVDEAEEQIALRRQQPAGRLRVNAAMPFMLHVVAPLVPDFRARYP
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECHHHHHHHHHHHHHCCHHHCCCC
QIELELNTNDLIIDLLEEDTDVAIRIGTLRDSTLRARLLGTRRLRVLASPAYLKAHGRPR
EEEEEECCCCEEEEEECCCCCEEEEEECCCCHHHHHHHHHHHHHHHHCCCHHEECCCCCC
HVDELQKHALLGFVQPESLNQWPLRGPYGDRLRIEPTLKASSGETLRQLALQGAGIVCLA
CHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHCCCCCEEEH
DFMTAEDRRAGDLMQVLQDATVEVLQPIHAVYYRNTQLASRIACFLDFLEARLADDKQ
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]