Click here to switch to the map view.

The map label for this gene is pgsA [H]

Identifier: 187928032

GI number: 187928032

Start: 990978

End: 991553

Strand: Direct

Name: pgsA [H]

Synonym: Rpic_0937

Alternate gene names: 187928032

Gene position: 990978-991553 (Clockwise)

Preceding gene: 187928031

Following gene: 187928033

Centisome position: 25.14

GC content: 61.46

Gene sequence:

>576_bases
ATGCCTTTCAACTTCCCGATCCTCCTGACCTGGTTGCGTGTGGCCATGATCCCGCTGGTGGTGGGCGTGTTCTACGTGCC
GGACACCTGGATGGCACTGCCCGCCAAGAACCTGACGGCCGCGGTGTTCTTCATCGTAGCAAGCCTCACTGATTGGTTCG
ACGGCTTTCTTGCTCGCCGCTGGAACCAGACCTCTGCTTTCGGTGCCTTCCTCGATCCGGTGGCCGACAAGCTGATGGTG
GCCGCCGCGCTGCTGGTGCTGCTGTCATTGGGCCGCGTGTCCGACGTCATCGCACTCGTCATCATTGGCCGCGAGATCAC
CATCTCCGCCCTGCGTGAGTGGATGGCGCAGATTGGCGCGTCGAAGAGCGTGGCCGTCAACTTTCTCGGCAAGCTGAAGA
CGACCTTCCAGATGATCGCAATTCCGCTGCTGCTGTTCGAGGGCCGCCTGTTCGGCATGATCGACGCGCAGGTGTGGGGC
ACATGGCTGATTTACGTGGCGGCAGTACTCACGCTGTGGTCGATGGCGTACTACATGAAGCTCGCCTGGCCGCAGATCCG
CGAGCGCGCAAAATGA

Upstream 100 bases:

>100_bases
CTCGCCGAAGAAATCTACCGTCAGTTGCATTGATCGGCGACAATGCCCCATCTTGTCGCGTGGGGTCGAGCTTGCGCGGC
GGTTGTCCTCTCGATTTGCC

Downstream 100 bases:

>100_bases
GCCTCTAAAAACTCTTGCGCAAAAGTATTGACGACGGCGATTCTTCTTTGCCATAATCTCGTTCTCGCGTTGCAGTGATG
TGACGCAAACGGTCTGGCAG

Product: CDP-diacylglycerol/glycerol-3-phosphate 3-phosphatidyltransferase

Products: NA

Alternate protein names: Phosphatidylglycerophosphate synthase; PGP synthase [H]

Number of amino acids: Translated: 191; Mature: 190

Protein sequence:

>191_residues
MPFNFPILLTWLRVAMIPLVVGVFYVPDTWMALPAKNLTAAVFFIVASLTDWFDGFLARRWNQTSAFGAFLDPVADKLMV
AAALLVLLSLGRVSDVIALVIIGREITISALREWMAQIGASKSVAVNFLGKLKTTFQMIAIPLLLFEGRLFGMIDAQVWG
TWLIYVAAVLTLWSMAYYMKLAWPQIRERAK

Sequences:

>Translated_191_residues
MPFNFPILLTWLRVAMIPLVVGVFYVPDTWMALPAKNLTAAVFFIVASLTDWFDGFLARRWNQTSAFGAFLDPVADKLMV
AAALLVLLSLGRVSDVIALVIIGREITISALREWMAQIGASKSVAVNFLGKLKTTFQMIAIPLLLFEGRLFGMIDAQVWG
TWLIYVAAVLTLWSMAYYMKLAWPQIRERAK
>Mature_190_residues
PFNFPILLTWLRVAMIPLVVGVFYVPDTWMALPAKNLTAAVFFIVASLTDWFDGFLARRWNQTSAFGAFLDPVADKLMVA
AALLVLLSLGRVSDVIALVIIGREITISALREWMAQIGASKSVAVNFLGKLKTTFQMIAIPLLLFEGRLFGMIDAQVWGT
WLIYVAAVLTLWSMAYYMKLAWPQIRERAK

Specific function: This protein catalyzes the committed step to the synthesis of the acidic phospholipids [H]

COG id: COG0558

COG function: function code I; Phosphatidylglycerophosphate synthase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDP-alcohol phosphatidyltransferase class-I family [H]

Homologues:

Organism=Escherichia coli, GI1788220, Length=185, Percent_Identity=52.4324324324324, Blast_Score=161, Evalue=2e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000462
- InterPro:   IPR004570 [H]

Pfam domain/function: PF01066 CDP-OH_P_transf [H]

EC number: =2.7.8.5 [H]

Molecular weight: Translated: 21419; Mature: 21288

Theoretical pI: Translated: 10.27; Mature: 10.27

Prosite motif: PS00379 CDP_ALCOHOL_P_TRANSF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPFNFPILLTWLRVAMIPLVVGVFYVPDTWMALPAKNLTAAVFFIVASLTDWFDGFLARR
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
WNQTSAFGAFLDPVADKLMVAAALLVLLSLGRVSDVIALVIIGREITISALREWMAQIGA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCC
SKSVAVNFLGKLKTTFQMIAIPLLLFEGRLFGMIDAQVWGTWLIYVAAVLTLWSMAYYMK
CHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LAWPQIRERAK
HHCHHHHHCCC
>Mature Secondary Structure 
PFNFPILLTWLRVAMIPLVVGVFYVPDTWMALPAKNLTAAVFFIVASLTDWFDGFLARR
CCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
WNQTSAFGAFLDPVADKLMVAAALLVLLSLGRVSDVIALVIIGREITISALREWMAQIGA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCC
SKSVAVNFLGKLKTTFQMIAIPLLLFEGRLFGMIDAQVWGTWLIYVAAVLTLWSMAYYMK
CHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LAWPQIRERAK
HHCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 14528314 [H]