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The map label for this gene is nagZ [H]

Identifier: 187928028

GI number: 187928028

Start: 985834

End: 986883

Strand: Direct

Name: nagZ [H]

Synonym: Rpic_0933

Alternate gene names: 187928028

Gene position: 985834-986883 (Clockwise)

Preceding gene: 187928027

Following gene: 187928031

Centisome position: 25.0

GC content: 64.57

Gene sequence:

>1050_bases
ATGACTCAAACCAAGAAGCAGAAGCGTCCAGGCCCGATCGTTCTGGATGTTGCCGGCCTGGAACTCGGCCTCGACGATGT
TCGACGCATTGCCCATCCATTGACGGGCGGCGTGATCCTGTTTGCCCGCAACTTTGAATCGCGCGCGCAGTTGACGGCGC
TCACGCAAGCCATTCGCGCCATTCGTAATGACGTGCTGATTTGCATCGACCACGAAGGCGGTCGCGTGCAGCGCGCCAAG
ACCGACGGTTTCACGCACCTGCCCGCCATGGGCGCGCTGGGCAAGCTATGGGACGCCGATGTGCTGGCCGCCACGCGCGC
TGCCACCGCCTGCGGCTACGTGCTGGCCGCTGAACTGAGGGCGTGCGATATCGACCTCAGCTTCACGCCCGTGCTCGATC
TCGACTACGGCAGCAGCAGCGTGATCGGCGATCGCGCGTTTCATCGCGACCCGCGGGTGGTTACGATGCTTGCCAACCAC
CTGACGCTGGGCCTGCGCCTGGCTGGCATGTCCAACTGCGGCAAGCATTTCCCCGGTCACGGCTACGTCCAGGCTGATTC
GCACGTCGCCGTGCCGGTGGACGAGCGTCCGCTGGAGGCCATCCTCGCTGACGACGCGCAGCCTTACGGCTGGATGGGCA
TCGGCCTGCAATCCGTGATGCCGGCGCACGTGATTTATTCAGCGGTCGATCCGAACCCGGCAGGCTTCTCTCGCTTCTGG
CTGCAGGACATGCTGCGCGCGCATTTCAACTTTGACGGCGTGATCTTCAGCGATGACCTGAGCATGGAAGGCGCGAGCGT
TGCCGGCACGGTGGTCGACGGTGCGCGAGCAGCGCTCACGGCCGGCTGCGACATGGTGCTGATCTGTAATGCGCCGGACA
AGGCCGATCAATTGCTCGGCGAGCTGGACGTGTCGATGGGCAAGGCATCGCAGCGGCGCGTGCGCCGGCTGTTTGGCGGC
CGGGCCGAGAAGGACTGGGCCAAGTTGCAGCAGCAATCGGCCTACAAGCAGGCGCTGCGTACGTTGCGCGAGGCGAAACT
CATCGCGTAG

Upstream 100 bases:

>100_bases
GGATCGCGCAGCATGGCCTTCATATCCAGATCAGTGTGACGGACGAGCGCGACTACGCAGTCGCCTTCGCCGTTGCCGAG
TTGCAAACCAAATCCTCCGC

Downstream 100 bases:

>100_bases
CGCCAAAACGCAAAAACGCGATCGCAAAAGAAAAGGCTCCCGAGGGAGCCTTTCTGCTTGCTGCGACGCCAGCTCTTACT
TGGCGCGGCTGCGGTACTCG

Product: beta-hexosaminidase

Products: NA

Alternate protein names: Beta-N-acetylhexosaminidase; N-acetyl-beta-glucosaminidase [H]

Number of amino acids: Translated: 349; Mature: 348

Protein sequence:

>349_residues
MTQTKKQKRPGPIVLDVAGLELGLDDVRRIAHPLTGGVILFARNFESRAQLTALTQAIRAIRNDVLICIDHEGGRVQRAK
TDGFTHLPAMGALGKLWDADVLAATRAATACGYVLAAELRACDIDLSFTPVLDLDYGSSSVIGDRAFHRDPRVVTMLANH
LTLGLRLAGMSNCGKHFPGHGYVQADSHVAVPVDERPLEAILADDAQPYGWMGIGLQSVMPAHVIYSAVDPNPAGFSRFW
LQDMLRAHFNFDGVIFSDDLSMEGASVAGTVVDGARAALTAGCDMVLICNAPDKADQLLGELDVSMGKASQRRVRRLFGG
RAEKDWAKLQQQSAYKQALRTLREAKLIA

Sequences:

>Translated_349_residues
MTQTKKQKRPGPIVLDVAGLELGLDDVRRIAHPLTGGVILFARNFESRAQLTALTQAIRAIRNDVLICIDHEGGRVQRAK
TDGFTHLPAMGALGKLWDADVLAATRAATACGYVLAAELRACDIDLSFTPVLDLDYGSSSVIGDRAFHRDPRVVTMLANH
LTLGLRLAGMSNCGKHFPGHGYVQADSHVAVPVDERPLEAILADDAQPYGWMGIGLQSVMPAHVIYSAVDPNPAGFSRFW
LQDMLRAHFNFDGVIFSDDLSMEGASVAGTVVDGARAALTAGCDMVLICNAPDKADQLLGELDVSMGKASQRRVRRLFGG
RAEKDWAKLQQQSAYKQALRTLREAKLIA
>Mature_348_residues
TQTKKQKRPGPIVLDVAGLELGLDDVRRIAHPLTGGVILFARNFESRAQLTALTQAIRAIRNDVLICIDHEGGRVQRAKT
DGFTHLPAMGALGKLWDADVLAATRAATACGYVLAAELRACDIDLSFTPVLDLDYGSSSVIGDRAFHRDPRVVTMLANHL
TLGLRLAGMSNCGKHFPGHGYVQADSHVAVPVDERPLEAILADDAQPYGWMGIGLQSVMPAHVIYSAVDPNPAGFSRFWL
QDMLRAHFNFDGVIFSDDLSMEGASVAGTVVDGARAALTAGCDMVLICNAPDKADQLLGELDVSMGKASQRRVRRLFGGR
AEKDWAKLQQQSAYKQALRTLREAKLIA

Specific function: Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides [H]

COG id: COG1472

COG function: function code G; Beta-glucosidase-related glycosidases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 3 family. NagZ subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787350, Length=311, Percent_Identity=45.3376205787781, Blast_Score=260, Evalue=1e-70,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022956
- InterPro:   IPR019800
- InterPro:   IPR001764
- InterPro:   IPR017853 [H]

Pfam domain/function: PF00933 Glyco_hydro_3 [H]

EC number: =3.2.1.52 [H]

Molecular weight: Translated: 37755; Mature: 37624

Theoretical pI: Translated: 7.29; Mature: 7.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQTKKQKRPGPIVLDVAGLELGLDDVRRIAHPLTGGVILFARNFESRAQLTALTQAIRA
CCCCCCCCCCCCEEEEECCCCCCHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHHH
IRNDVLICIDHEGGRVQRAKTDGFTHLPAMGALGKLWDADVLAATRAATACGYVLAAELR
HHCCEEEEEECCCCEEEEECCCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
ACDIDLSFTPVLDLDYGSSSVIGDRAFHRDPRVVTMLANHLTLGLRLAGMSNCGKHFPGH
HEECCCCCCEEEEECCCCCCCCCCHHHCCCCHHHHHHHHHHHEEEEEECCCCCCCCCCCC
GYVQADSHVAVPVDERPLEAILADDAQPYGWMGIGLQSVMPAHVIYSAVDPNPAGFSRFW
CEEEECCEEEECCCCCCHHHHHHCCCCCCCEEECCHHHHHHHHHEEECCCCCCCCHHHHH
LQDMLRAHFNFDGVIFSDDLSMEGASVAGTVVDGARAALTAGCDMVLICNAPDKADQLLG
HHHHHHHHCCCCCEEEECCCCCCCCCEEEEHHCCHHHHHHCCCCEEEEECCCCHHHHHHH
ELDVSMGKASQRRVRRLFGGRAEKDWAKLQQQSAYKQALRTLREAKLIA
HHHHHCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TQTKKQKRPGPIVLDVAGLELGLDDVRRIAHPLTGGVILFARNFESRAQLTALTQAIRA
CCCCCCCCCCCEEEEECCCCCCHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHHH
IRNDVLICIDHEGGRVQRAKTDGFTHLPAMGALGKLWDADVLAATRAATACGYVLAAELR
HHCCEEEEEECCCCEEEEECCCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
ACDIDLSFTPVLDLDYGSSSVIGDRAFHRDPRVVTMLANHLTLGLRLAGMSNCGKHFPGH
HEECCCCCCEEEEECCCCCCCCCCHHHCCCCHHHHHHHHHHHEEEEEECCCCCCCCCCCC
GYVQADSHVAVPVDERPLEAILADDAQPYGWMGIGLQSVMPAHVIYSAVDPNPAGFSRFW
CEEEECCEEEECCCCCCHHHHHHCCCCCCCEEECCHHHHHHHHHEEECCCCCCCCHHHHH
LQDMLRAHFNFDGVIFSDDLSMEGASVAGTVVDGARAALTAGCDMVLICNAPDKADQLLG
HHHHHHHHCCCCCEEEECCCCCCCCCEEEEHHCCHHHHHHCCCCEEEEECCCCHHHHHHH
ELDVSMGKASQRRVRRLFGGRAEKDWAKLQQQSAYKQALRTLREAKLIA
HHHHHCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12910271 [H]