Click here to switch to the map view.

The map label for this gene is acpS [H]

Identifier: 187928027

GI number: 187928027

Start: 985394

End: 985837

Strand: Direct

Name: acpS [H]

Synonym: Rpic_0932

Alternate gene names: 187928027

Gene position: 985394-985837 (Clockwise)

Preceding gene: 187928026

Following gene: 187928028

Centisome position: 24.99

GC content: 64.86

Gene sequence:

>444_bases
ATGAGCGGACGGGGCGCAGCCGCCTCGGTGTCCGGTGCGATTTACGGCATCGGCACCGACATCATCCAGATCGAGCGCGT
CGAAGGCGTGATGCAGCGGACCAACGGCCGCTTCGCCGAAAAGGTGCTGGGCCCCGAAGAGCTGCGCGTCTACCATGCCC
GCAAGGCGCGCTCTGAGCGGCGGGGCCTTGCGTTTCTTGCCACGCGCTTTGCCGCCAAGGAAGCCGTGTCCAAGGCCATC
GGCCTGGGCATGCGCTGGCCGATGACGTGGCGTGCGGTACAGACGCTGAACTTGCCATCCGGCCAACCGGTGGTGCACTA
CAGCGGTGAACTGGCCGACTGGATCGCGCAGCATGGCCTTCATATCCAGATCAGTGTGACGGACGAGCGCGACTACGCAG
TCGCCTTCGCCGTTGCCGAGTTGCAAACCAAATCCTCCGCATGA

Upstream 100 bases:

>100_bases
TTGCCGGGTGGCAGAACGCGGTGCGCGAGATGAAGGCGATCATGGTTGCGGCTCGGCTGTCGTCCACGACCCCGGCGGCC
GCACACCCGGGCGTGCCTGT

Downstream 100 bases:

>100_bases
CTCAAACCAAGAAGCAGAAGCGTCCAGGCCCGATCGTTCTGGATGTTGCCGGCCTGGAACTCGGCCTCGACGATGTTCGA
CGCATTGCCCATCCATTGAC

Product: 4'-phosphopantetheinyl transferase

Products: NA

Alternate protein names: Holo-ACP synthase; 4'-phosphopantetheinyl transferase AcpS [H]

Number of amino acids: Translated: 147; Mature: 146

Protein sequence:

>147_residues
MSGRGAAASVSGAIYGIGTDIIQIERVEGVMQRTNGRFAEKVLGPEELRVYHARKARSERRGLAFLATRFAAKEAVSKAI
GLGMRWPMTWRAVQTLNLPSGQPVVHYSGELADWIAQHGLHIQISVTDERDYAVAFAVAELQTKSSA

Sequences:

>Translated_147_residues
MSGRGAAASVSGAIYGIGTDIIQIERVEGVMQRTNGRFAEKVLGPEELRVYHARKARSERRGLAFLATRFAAKEAVSKAI
GLGMRWPMTWRAVQTLNLPSGQPVVHYSGELADWIAQHGLHIQISVTDERDYAVAFAVAELQTKSSA
>Mature_146_residues
SGRGAAASVSGAIYGIGTDIIQIERVEGVMQRTNGRFAEKVLGPEELRVYHARKARSERRGLAFLATRFAAKEAVSKAIG
LGMRWPMTWRAVQTLNLPSGQPVVHYSGELADWIAQHGLHIQISVTDERDYAVAFAVAELQTKSSA

Specific function: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein [H]

COG id: COG0736

COG function: function code I; Phosphopantetheinyl transferase (holo-ACP synthase)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the P-Pant transferase superfamily. AcpS family [H]

Homologues:

Organism=Escherichia coli, GI1788916, Length=129, Percent_Identity=34.1085271317829, Blast_Score=77, Evalue=3e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008278
- InterPro:   IPR002582
- InterPro:   IPR004568
- ProDom:   PD004282 [H]

Pfam domain/function: PF01648 ACPS [H]

EC number: =2.7.8.7 [H]

Molecular weight: Translated: 16038; Mature: 15906

Theoretical pI: Translated: 10.14; Mature: 10.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGRGAAASVSGAIYGIGTDIIQIERVEGVMQRTNGRFAEKVLGPEELRVYHARKARSER
CCCCCCCEECCCEEEECCCCCEEHHHHHHHHHHCCCHHHHHHCCHHHHHHHHHHHHHHHH
RGLAFLATRFAAKEAVSKAIGLGMRWPMTWRAVQTLNLPSGQPVVHYSGELADWIAQHGL
CCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCCCEEEEECCHHHHHHHHCCC
HIQISVTDERDYAVAFAVAELQTKSSA
EEEEEEECCCCEEEEHHHHHHHHCCCC
>Mature Secondary Structure 
SGRGAAASVSGAIYGIGTDIIQIERVEGVMQRTNGRFAEKVLGPEELRVYHARKARSER
CCCCCCEECCCEEEECCCCCEEHHHHHHHHHHCCCHHHHHHCCHHHHHHHHHHHHHHHH
RGLAFLATRFAAKEAVSKAIGLGMRWPMTWRAVQTLNLPSGQPVVHYSGELADWIAQHGL
CCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCCCEEEEECCHHHHHHHHCCC
HIQISVTDERDYAVAFAVAELQTKSSA
EEEEEEECCCCEEEEHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]