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The map label for this gene is gph [C]

Identifier: 187928002

GI number: 187928002

Start: 963423

End: 964082

Strand: Direct

Name: gph [C]

Synonym: Rpic_0907

Alternate gene names: 187928002

Gene position: 963423-964082 (Clockwise)

Preceding gene: 187928001

Following gene: 187928003

Centisome position: 24.44

GC content: 62.88

Gene sequence:

>660_bases
ATGCCGCAGCAGCGCTTTGATCTGATCGTCTTCGATTGGGATGGCACGTTGATGGATTCGACGTCGGCCATCACCCGGTC
GATCCAGCTCGCATGCCGGGATCTTGACCTGCCGGTGCCCGACGATGCACGGGCGAGCCACGTGATTGGCCTGGGCCTGC
GGGATGCGCTCGAATATGCCGTCCCGACGCTTGATCCCGCCGACTACGGCAAGCTGGCGGACCGGTATCGTTTCCATTAC
CTCAGCCGTGATGCGCATCTCGTCCTGTTTCCGGGCGTGCGAGAAATGCTGGAAGCACTGCGCCGCCAGAACTATCTGCT
GGCTGTGGCGACGGGCAAGTCCCGCGTGGGCCTGCAACGTGCGATGGAGGCGACAAATCTGACGGGCGTGTTCGACAACA
CGCGTTGCGCCGATGAGACGTTCTCTAAGCCGCACCCCGCCATGCTGCTCGAACTCACGCGCGATCTCGGCATGGAGGTC
GAGCGCACCGTGATGATCGGCGACACGACGCACGATCTGCAAATGGCCGCCAATGCAGGCGCCGCCGGCGTGGCCGTCAC
ATACGGGGCGCATCCTGCCGATGTGCTGGATTCGCTTACGCCGCTGTATAGCGCCAAGTCGGTTCCCGATCTGCACAATT
GGCTGACGCAACATGCCTGA

Upstream 100 bases:

>100_bases
CAACTGACGCATCCGCATAGCGGTGAAGTCGTCACGTTCAATGCGCCGTTGCCCGCCGAGTGTACCGATTTCCTCAACGC
TTTCCAGGGCCCCGATTCCG

Downstream 100 bases:

>100_bases
CATGGCGGAGCCGGTTCGTGTATGCGAAAGCGCTGCGCTGGAAGACGGCGGTCTGGGTGTCCGGTTTCAGGTGGACGTGC
GCGGTCGGCTCGTCAGCGCG

Product: HAD-superfamily hydrolase

Products: NA

Alternate protein names: PGP; PGPase [H]

Number of amino acids: Translated: 219; Mature: 218

Protein sequence:

>219_residues
MPQQRFDLIVFDWDGTLMDSTSAITRSIQLACRDLDLPVPDDARASHVIGLGLRDALEYAVPTLDPADYGKLADRYRFHY
LSRDAHLVLFPGVREMLEALRRQNYLLAVATGKSRVGLQRAMEATNLTGVFDNTRCADETFSKPHPAMLLELTRDLGMEV
ERTVMIGDTTHDLQMAANAGAAGVAVTYGAHPADVLDSLTPLYSAKSVPDLHNWLTQHA

Sequences:

>Translated_219_residues
MPQQRFDLIVFDWDGTLMDSTSAITRSIQLACRDLDLPVPDDARASHVIGLGLRDALEYAVPTLDPADYGKLADRYRFHY
LSRDAHLVLFPGVREMLEALRRQNYLLAVATGKSRVGLQRAMEATNLTGVFDNTRCADETFSKPHPAMLLELTRDLGMEV
ERTVMIGDTTHDLQMAANAGAAGVAVTYGAHPADVLDSLTPLYSAKSVPDLHNWLTQHA
>Mature_218_residues
PQQRFDLIVFDWDGTLMDSTSAITRSIQLACRDLDLPVPDDARASHVIGLGLRDALEYAVPTLDPADYGKLADRYRFHYL
SRDAHLVLFPGVREMLEALRRQNYLLAVATGKSRVGLQRAMEATNLTGVFDNTRCADETFSKPHPAMLLELTRDLGMEVE
RTVMIGDTTHDLQMAANAGAAGVAVTYGAHPADVLDSLTPLYSAKSVPDLHNWLTQHA

Specific function: Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stres

COG id: COG0546

COG function: function code R; Predicted phosphatases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family [H]

Homologues:

Organism=Escherichia coli, GI1789787, Length=228, Percent_Identity=28.5087719298246, Blast_Score=77, Evalue=7e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006439
- InterPro:   IPR006402
- InterPro:   IPR005833
- InterPro:   IPR000150
- InterPro:   IPR006346
- InterPro:   IPR023198 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: =3.1.3.18 [H]

Molecular weight: Translated: 24179; Mature: 24048

Theoretical pI: Translated: 5.26; Mature: 5.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPQQRFDLIVFDWDGTLMDSTSAITRSIQLACRDLDLPVPDDARASHVIGLGLRDALEYA
CCCCCEEEEEECCCCCEECCHHHHHHHHHHHHHHCCCCCCCCCCCCCEEECCHHHHHHHH
VPTLDPADYGKLADRYRFHYLSRDAHLVLFPGVREMLEALRRQNYLLAVATGKSRVGLQR
CCCCCCCHHHHHHHHHHHHEECCCCEEEECCCHHHHHHHHHHCCEEEEEECCCCHHHHHH
AMEATNLTGVFDNTRCADETFSKPHPAMLLELTRDLGMEVERTVMIGDTTHDLQMAANAG
HHHHHCCCCCCCCCCCCHHHCCCCCHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHCCCC
AAGVAVTYGAHPADVLDSLTPLYSAKSVPDLHNWLTQHA
CCCEEEEECCCHHHHHHHHHHHHCCCCCCHHHHHHHHCC
>Mature Secondary Structure 
PQQRFDLIVFDWDGTLMDSTSAITRSIQLACRDLDLPVPDDARASHVIGLGLRDALEYA
CCCCEEEEEECCCCCEECCHHHHHHHHHHHHHHCCCCCCCCCCCCCEEECCHHHHHHHH
VPTLDPADYGKLADRYRFHYLSRDAHLVLFPGVREMLEALRRQNYLLAVATGKSRVGLQR
CCCCCCCHHHHHHHHHHHHEECCCCEEEECCCHHHHHHHHHHCCEEEEEECCCCHHHHHH
AMEATNLTGVFDNTRCADETFSKPHPAMLLELTRDLGMEVERTVMIGDTTHDLQMAANAG
HHHHHCCCCCCCCCCCCHHHCCCCCHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHCCCC
AAGVAVTYGAHPADVLDSLTPLYSAKSVPDLHNWLTQHA
CCCEEEEECCCHHHHHHHHHHHHCCCCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA