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The map label for this gene is htpG [H]

Identifier: 187927946

GI number: 187927946

Start: 903670

End: 905601

Strand: Direct

Name: htpG [H]

Synonym: Rpic_0851

Alternate gene names: 187927946

Gene position: 903670-905601 (Clockwise)

Preceding gene: 187927945

Following gene: 187927947

Centisome position: 22.92

GC content: 62.68

Gene sequence:

>1932_bases
ATGCACACCATGAGCGCACCGCACGAGAAGATGGCTTTCCAGGCAGAAGTGAAGCAGCTTCTGCACCTGATGATCCACTC
GCTATACAGCAACAAGGAAATCTTCCTGCGGGAACTGGTTTCCAATGCTTCAGATGCGGTGGACAAGCTGCGCTTTGAGG
GTATCGCCAATCCGTCGCTGCTGGAAGGCGGCGGTGAGCTAGGCATCCGCATCGGCTTTGATGCCGCCGCGCGCACCATC
ACGATTGCCGACAACGGCATCGGCATGAGCCGCGACGAGGCCATCCGCAACCTCGGCACCATCGCCCGCTCGGGCACGCG
CGAGTTCTTCAGCCAGCTTTCGGGCGACCAGCAGAAGGATGCTGCGCTGATCGGCCAGTTTGGCGTGGGCTTCTACTCGG
CATTCATCGTGGCCGACCGCGTGACGGTGGAATCGCGCCGCGCCGGTGTGGCCGCCAATGAAGCCGTGCGCTGGGAAAGC
ACCGGCGACGGCGAATTCACTGTCGACACCATCGAACGTGCCGAGCGAGGCACCACCATCACGCTGCACCTGCGCGAGGG
TGAGGACGATTTCCTCTCCGCTTGGCGCATCAAGTCGGTCGTGCAAAAGTATTCGGACCACATCTCCCTGCCGATCCAGA
TGCGCAAGGAAGCGTGGGACGAAGAGAAGAAGGCGATGGTGGCCCAGGACGAATGGGAAACCATCAACCAGGGCAGCGCC
CTGTGGGCACGCCCGCGCGCTGACGTGACCGATGATCAGTACATCGCGTTCTACCAGCACATCGCCCACGAAAACGGCAA
GCCGCTCGCCTGGACGCACAACCGTGTGGAAGGCCGCAGCGAATACACGCAACTGCTGTACATCCCGACCAACGCGCCGT
TCGACCTGTGGGACCGCGAGCGCCGCAGCGGCCTGAAGCTGTACGTCAAGCGCGTCTTCATCATGGACGACGCCGAGCAA
CTGCTGCCGGCCTACCAGCGCTTCGTGAAGGGCGTGATCGATTCGGCCGATTTGCCGCTGAATGTCTCGCGCGAAATCCT
GCAGGAAAGCCGCGACGTGAAAGCCATCCGCGAGGGTTCGACCAAGCGCGTGCTCGGCATGCTCGAATCGATGGCCGAGT
CGGATGACGCAGCCGAGAAGGAGAAGTACGCCACGTTCTGGCAGAACTTCGGTCAGGTGCTCAAGGAGGGCATCGGCGAG
GACCACGCCAACAAGGACCGCATTGCCAAGCTGCTCCGCTTTGCTTCCACGCACAACGAAGACAGCGCCCAGACCGTCTC
GCTGGCCGATTACGTCGGCCGCATGAAGGAAGGTCAGGACAAGATCTACTACGTGACCGCCGAAAACTGGACGGCGGCCA
AGTCGAGCCCGCATCTGGAAATCTTCCGCAAGAAGGGTGTGGAAGTGCTGCTGCTGACCGACCGCGTGGACGAGTGGATG
CTCTCGTTCCTGCACGATTTCGAAGAGAAGGAACTGGTGTCGGTTGCGCGTGGCGATCTCGACCTGGGCGCCTTGGAAGG
CGAAGCCGAGAAGGCCGAGCACGCCAAGGTGGAAGGCGAGTTCAAGCCGCTGGTCGAGCGCGCCAAGGCGGTGCTCAGCG
ACAAGGCCAAGGACGTGCGCATCACGCATCGCCTGACCGATTCGCCGTCGTGCCTGGTGGCCGATGAAGGCGACATCAGC
GGCACGCTGGCCCGTCTGCTCAAGCAGGCCGGCCAACAGGCGCCTGACAGCAAACCCGTGCTGGAACTGAACCCGACGCA
CCCGCTTGTGCGCAAGCTCGCGCTGCTGGAAACCGTGACCGGCAACGAAGCCGACCGCGCCGCGTTTGAAGATCGCCTGC
ATGTGCTGTTCGATCAGGCACTGTTGGCAGAGGGTGGCGCATTGGCCGACCCGGCAGCCTACGTGCAACGTGTGAACCGC
CTGCTGGCCTGA

Upstream 100 bases:

>100_bases
GGGGCTTGAAAACCGGGCGCCACGCCCTATCTAGCTTCACAAATTCATGCGGGCGCGCGCAAGGTGTAGCCCGCTTCTCT
TTCCACTTTCCAGATTTTCT

Downstream 100 bases:

>100_bases
CGACAAGCGTGACGCTCAAGCGATGCTTTCCGCCCGTGGTCGACGCGCACACGCGCGTGCTGATCCTGGGCAGCCTGCCC
GGTGAAGCATCGCTTGCGCA

Product: heat shock protein 90

Products: NA

Alternate protein names: Heat shock protein htpG; High temperature protein G [H]

Number of amino acids: Translated: 643; Mature: 643

Protein sequence:

>643_residues
MHTMSAPHEKMAFQAEVKQLLHLMIHSLYSNKEIFLRELVSNASDAVDKLRFEGIANPSLLEGGGELGIRIGFDAAARTI
TIADNGIGMSRDEAIRNLGTIARSGTREFFSQLSGDQQKDAALIGQFGVGFYSAFIVADRVTVESRRAGVAANEAVRWES
TGDGEFTVDTIERAERGTTITLHLREGEDDFLSAWRIKSVVQKYSDHISLPIQMRKEAWDEEKKAMVAQDEWETINQGSA
LWARPRADVTDDQYIAFYQHIAHENGKPLAWTHNRVEGRSEYTQLLYIPTNAPFDLWDRERRSGLKLYVKRVFIMDDAEQ
LLPAYQRFVKGVIDSADLPLNVSREILQESRDVKAIREGSTKRVLGMLESMAESDDAAEKEKYATFWQNFGQVLKEGIGE
DHANKDRIAKLLRFASTHNEDSAQTVSLADYVGRMKEGQDKIYYVTAENWTAAKSSPHLEIFRKKGVEVLLLTDRVDEWM
LSFLHDFEEKELVSVARGDLDLGALEGEAEKAEHAKVEGEFKPLVERAKAVLSDKAKDVRITHRLTDSPSCLVADEGDIS
GTLARLLKQAGQQAPDSKPVLELNPTHPLVRKLALLETVTGNEADRAAFEDRLHVLFDQALLAEGGALADPAAYVQRVNR
LLA

Sequences:

>Translated_643_residues
MHTMSAPHEKMAFQAEVKQLLHLMIHSLYSNKEIFLRELVSNASDAVDKLRFEGIANPSLLEGGGELGIRIGFDAAARTI
TIADNGIGMSRDEAIRNLGTIARSGTREFFSQLSGDQQKDAALIGQFGVGFYSAFIVADRVTVESRRAGVAANEAVRWES
TGDGEFTVDTIERAERGTTITLHLREGEDDFLSAWRIKSVVQKYSDHISLPIQMRKEAWDEEKKAMVAQDEWETINQGSA
LWARPRADVTDDQYIAFYQHIAHENGKPLAWTHNRVEGRSEYTQLLYIPTNAPFDLWDRERRSGLKLYVKRVFIMDDAEQ
LLPAYQRFVKGVIDSADLPLNVSREILQESRDVKAIREGSTKRVLGMLESMAESDDAAEKEKYATFWQNFGQVLKEGIGE
DHANKDRIAKLLRFASTHNEDSAQTVSLADYVGRMKEGQDKIYYVTAENWTAAKSSPHLEIFRKKGVEVLLLTDRVDEWM
LSFLHDFEEKELVSVARGDLDLGALEGEAEKAEHAKVEGEFKPLVERAKAVLSDKAKDVRITHRLTDSPSCLVADEGDIS
GTLARLLKQAGQQAPDSKPVLELNPTHPLVRKLALLETVTGNEADRAAFEDRLHVLFDQALLAEGGALADPAAYVQRVNR
LLA
>Mature_643_residues
MHTMSAPHEKMAFQAEVKQLLHLMIHSLYSNKEIFLRELVSNASDAVDKLRFEGIANPSLLEGGGELGIRIGFDAAARTI
TIADNGIGMSRDEAIRNLGTIARSGTREFFSQLSGDQQKDAALIGQFGVGFYSAFIVADRVTVESRRAGVAANEAVRWES
TGDGEFTVDTIERAERGTTITLHLREGEDDFLSAWRIKSVVQKYSDHISLPIQMRKEAWDEEKKAMVAQDEWETINQGSA
LWARPRADVTDDQYIAFYQHIAHENGKPLAWTHNRVEGRSEYTQLLYIPTNAPFDLWDRERRSGLKLYVKRVFIMDDAEQ
LLPAYQRFVKGVIDSADLPLNVSREILQESRDVKAIREGSTKRVLGMLESMAESDDAAEKEKYATFWQNFGQVLKEGIGE
DHANKDRIAKLLRFASTHNEDSAQTVSLADYVGRMKEGQDKIYYVTAENWTAAKSSPHLEIFRKKGVEVLLLTDRVDEWM
LSFLHDFEEKELVSVARGDLDLGALEGEAEKAEHAKVEGEFKPLVERAKAVLSDKAKDVRITHRLTDSPSCLVADEGDIS
GTLARLLKQAGQQAPDSKPVLELNPTHPLVRKLALLETVTGNEADRAAFEDRLHVLFDQALLAEGGALADPAAYVQRVNR
LLA

Specific function: Molecular chaperone. Has ATPase activity [H]

COG id: COG0326

COG function: function code O; Molecular chaperone, HSP90 family

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heat shock protein 90 family [H]

Homologues:

Organism=Homo sapiens, GI4507677, Length=692, Percent_Identity=39.4508670520231, Blast_Score=458, Evalue=1e-129,
Organism=Homo sapiens, GI20149594, Length=687, Percent_Identity=37.4090247452693, Blast_Score=431, Evalue=1e-120,
Organism=Homo sapiens, GI155722983, Length=650, Percent_Identity=35.8461538461538, Blast_Score=357, Evalue=3e-98,
Organism=Homo sapiens, GI154146191, Length=419, Percent_Identity=36.0381861575179, Blast_Score=259, Evalue=4e-69,
Organism=Homo sapiens, GI153792590, Length=419, Percent_Identity=36.2768496420048, Blast_Score=257, Evalue=2e-68,
Organism=Escherichia coli, GI1786679, Length=636, Percent_Identity=57.7044025157233, Blast_Score=756, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17559162, Length=682, Percent_Identity=37.9765395894428, Blast_Score=448, Evalue=1e-126,
Organism=Caenorhabditis elegans, GI17542208, Length=679, Percent_Identity=39.0279823269514, Blast_Score=423, Evalue=1e-118,
Organism=Caenorhabditis elegans, GI115535205, Length=654, Percent_Identity=32.8746177370031, Blast_Score=324, Evalue=1e-88,
Organism=Caenorhabditis elegans, GI115535167, Length=440, Percent_Identity=34.7727272727273, Blast_Score=258, Evalue=7e-69,
Organism=Saccharomyces cerevisiae, GI6323840, Length=686, Percent_Identity=37.4635568513119, Blast_Score=448, Evalue=1e-126,
Organism=Saccharomyces cerevisiae, GI6325016, Length=690, Percent_Identity=37.1014492753623, Blast_Score=444, Evalue=1e-125,
Organism=Drosophila melanogaster, GI17647529, Length=696, Percent_Identity=37.0689655172414, Blast_Score=457, Evalue=1e-128,
Organism=Drosophila melanogaster, GI21357739, Length=687, Percent_Identity=36.3901018922853, Blast_Score=413, Evalue=1e-115,
Organism=Drosophila melanogaster, GI24586016, Length=660, Percent_Identity=33.9393939393939, Blast_Score=342, Evalue=4e-94,

Paralogues:

None

Copy number: 640 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 2419 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR019805
- InterPro:   IPR001404
- InterPro:   IPR020575
- InterPro:   IPR020568 [H]

Pfam domain/function: PF02518 HATPase_c; PF00183 HSP90 [H]

EC number: NA

Molecular weight: Translated: 71967; Mature: 71967

Theoretical pI: Translated: 5.12; Mature: 5.12

Prosite motif: PS00298 HSP90

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHTMSAPHEKMAFQAEVKQLLHLMIHSLYSNKEIFLRELVSNASDAVDKLRFEGIANPSL
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
LEGGGELGIRIGFDAAARTITIADNGIGMSRDEAIRNLGTIARSGTREFFSQLSGDQQKD
HCCCCCEEEEEECCCCCCEEEEECCCCCCCHHHHHHHHHHHHHCCHHHHHHHHCCCCHHH
AALIGQFGVGFYSAFIVADRVTVESRRAGVAANEAVRWESTGDGEFTVDTIERAERGTTI
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCCCEEHHHHHHHHCCCEE
TLHLREGEDDFLSAWRIKSVVQKYSDHISLPIQMRKEAWDEEKKAMVAQDEWETINQGSA
EEEEECCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCHHHHHHHCCHHHHHHCCCCC
LWARPRADVTDDQYIAFYQHIAHENGKPLAWTHNRVEGRSEYTQLLYIPTNAPFDLWDRE
EEECCCCCCCCCHHHHHHHHHHHCCCCCEEEECCCCCCCCCCEEEEEEECCCCCCHHHHH
RRSGLKLYVKRVFIMDDAEQLLPAYQRFVKGVIDSADLPLNVSREILQESRDVKAIREGS
HHCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCC
TKRVLGMLESMAESDDAAEKEKYATFWQNFGQVLKEGIGEDHANKDRIAKLLRFASTHNE
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCC
DSAQTVSLADYVGRMKEGQDKIYYVTAENWTAAKSSPHLEIFRKKGVEVLLLTDRVDEWM
CCHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCHHHHHHCCCEEEEEECHHHHHH
LSFLHDFEEKELVSVARGDLDLGALEGEAEKAEHAKVEGEFKPLVERAKAVLSDKAKDVR
HHHHHCCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCEE
ITHRLTDSPSCLVADEGDISGTLARLLKQAGQQAPDSKPVLELNPTHPLVRKLALLETVT
EEEEECCCCCEEEECCCCCHHHHHHHHHHHCCCCCCCCCEEEECCCCHHHHHHHHHHHHC
GNEADRAAFEDRLHVLFDQALLAEGGALADPAAYVQRVNRLLA
CCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MHTMSAPHEKMAFQAEVKQLLHLMIHSLYSNKEIFLRELVSNASDAVDKLRFEGIANPSL
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
LEGGGELGIRIGFDAAARTITIADNGIGMSRDEAIRNLGTIARSGTREFFSQLSGDQQKD
HCCCCCEEEEEECCCCCCEEEEECCCCCCCHHHHHHHHHHHHHCCHHHHHHHHCCCCHHH
AALIGQFGVGFYSAFIVADRVTVESRRAGVAANEAVRWESTGDGEFTVDTIERAERGTTI
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCCCEEHHHHHHHHCCCEE
TLHLREGEDDFLSAWRIKSVVQKYSDHISLPIQMRKEAWDEEKKAMVAQDEWETINQGSA
EEEEECCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCHHHHHHHCCHHHHHHCCCCC
LWARPRADVTDDQYIAFYQHIAHENGKPLAWTHNRVEGRSEYTQLLYIPTNAPFDLWDRE
EEECCCCCCCCCHHHHHHHHHHHCCCCCEEEECCCCCCCCCCEEEEEEECCCCCCHHHHH
RRSGLKLYVKRVFIMDDAEQLLPAYQRFVKGVIDSADLPLNVSREILQESRDVKAIREGS
HHCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCC
TKRVLGMLESMAESDDAAEKEKYATFWQNFGQVLKEGIGEDHANKDRIAKLLRFASTHNE
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCC
DSAQTVSLADYVGRMKEGQDKIYYVTAENWTAAKSSPHLEIFRKKGVEVLLLTDRVDEWM
CCHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCHHHHHHCCCEEEEEECHHHHHH
LSFLHDFEEKELVSVARGDLDLGALEGEAEKAEHAKVEGEFKPLVERAKAVLSDKAKDVR
HHHHHCCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCEE
ITHRLTDSPSCLVADEGDISGTLARLLKQAGQQAPDSKPVLELNPTHPLVRKLALLETVT
EEEEECCCCCEEEECCCCCHHHHHHHHHHHCCCCCCCCCEEEECCCCHHHHHHHHHHHHC
GNEADRAAFEDRLHVLFDQALLAEGGALADPAAYVQRVNRLLA
CCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]