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The map label for this gene is udg [H]

Identifier: 187927879

GI number: 187927879

Start: 829226

End: 830590

Strand: Direct

Name: udg [H]

Synonym: Rpic_0783

Alternate gene names: 187927879

Gene position: 829226-830590 (Clockwise)

Preceding gene: 187927878

Following gene: 187927880

Centisome position: 21.03

GC content: 62.56

Gene sequence:

>1365_bases
ATGAAAATCACCATCATCGGTAGCGGTTATGTCGGACTAGTCACCGGCGCATGTCTGGCGGAGCTGGGCAACGATGTGTT
CTGTCTCGACGTCGACCAGAAGAAGATCGACCTGCTCAACGCCGGCGGCGTGCCCATCTACGAACCGGGACTGAAGGAGT
TGATCGAGCGTAATCGCGCGGCCGGCCGCATCCAGTTTTCGACCGACGTGGCTGCCAGCGTGGCGCACGGCGACGTGCAG
TTCATCGCTGTGGGCACGCCGCCCGATGAAGACGGCTCGGCCGACCTGAAGTACGTGTTGGCGGCCGCCCGCAACATCGC
CCAGCACATGACGGGCTTCAAGGTGATTGTCGACAAATCGACGGTGCCGGTGGGAACGGGCGACAAGGTGCGCGCTGCAG
TGGGTGAAGTGCTTGCTACGCGCGGCAAGTCTGACATCGGCTTCTCGGTCGTGTCGAACCCCGAATTCCTGAAAGAAGGC
GCCGCGGTGGACGACTTCATGCGCCCGGACCGCATCGTGCTTGGCACGTATGGCGATAACAATGGCCTGCGTGCCAAGGC
CATCATGCGTACGCTTTACGCGCCGTTCAATCGCAACCATGAGCGCACGTTCTACATGGACGTGCGCTCCGCCGAATTCA
CCAAGTACGCCGCCAATTCGATGCTGGCCACGCGCATCTCGTTCATGAACGAGATGGCCAATCTGGCCGACAAGGTGGGC
GCGGACATTGAACTCGTTCGCCTGGGCATCGGTTCCGACCCGCGTATCGGCTACAGCTTCCTCTACGCCGGCACCGGCTA
CGGCGGGTCGTGTTTCCCGAAGGACGTGCAGGCGCTGGTGCGCACGGCGCAGGAGTACGGTCAGACGCTGCACGTGCTGG
AAGCCGTTGAGGCCGTCAACGACAAGCAGAAGGAAGTGCTGGTCGGCAAGATCGAAGACCGCATGGGTGCCGACCTGACC
GGCCGCACGTTCGCCATCTGGGGTCTGGCGTTCAAGCCGAACACCGACGACATGCGCGAAGCACCGAGCCGCAACCTGAT
TGCTGCGCTGCTGGCGCGTGGCGCGCGCGTGCAGGTGTATGACCCGGTTGCGATGGAAGAGGCCCGCCATGCGCTGGGGC
TTGATCTTTCTTCGGAACAACTGGAACGCGTGGCGTTCTGCGCCGGTCAGATGGACGCGCTTAAGGATGCCGACGCACTG
GTCATCGTGACCGAGTGGAAGGCGTTCCGCAGCCCGGACTTCAACGCCGTGAAGGCCCTGTTGAAGACGCCGATGGTGTT
CGACGGCCGCAATCTGTTCGAGCCGCAAGCCATGCGCGATGCGGGCTTTGAATATCAGGCCATCGGGCGCTCCACCCAAT
CGTAA

Upstream 100 bases:

>100_bases
GACGCTCGGCGGCAGTGGCGGCGCCAGCATGTAATTCAGTCCGGCGCGGCAGGTGTGTGCAACGGCCGCGCTGGCGCTTT
TTCAATCTTTAAGTGTTCGT

Downstream 100 bases:

>100_bases
TCACCGACCCACCGGCCGCTGCCGACGCCCAGACTCATGACCACGCTCGCTTCCGAACAGATCCACGCCGCCCGTATCCT
CGTGGTCGGCGACATGATGC

Product: nucleotide sugar dehydrogenase

Products: NA

Alternate protein names: UDP-Glc dehydrogenase; UDP-GlcDH; UDPGDH [H]

Number of amino acids: Translated: 454; Mature: 454

Protein sequence:

>454_residues
MKITIIGSGYVGLVTGACLAELGNDVFCLDVDQKKIDLLNAGGVPIYEPGLKELIERNRAAGRIQFSTDVAASVAHGDVQ
FIAVGTPPDEDGSADLKYVLAAARNIAQHMTGFKVIVDKSTVPVGTGDKVRAAVGEVLATRGKSDIGFSVVSNPEFLKEG
AAVDDFMRPDRIVLGTYGDNNGLRAKAIMRTLYAPFNRNHERTFYMDVRSAEFTKYAANSMLATRISFMNEMANLADKVG
ADIELVRLGIGSDPRIGYSFLYAGTGYGGSCFPKDVQALVRTAQEYGQTLHVLEAVEAVNDKQKEVLVGKIEDRMGADLT
GRTFAIWGLAFKPNTDDMREAPSRNLIAALLARGARVQVYDPVAMEEARHALGLDLSSEQLERVAFCAGQMDALKDADAL
VIVTEWKAFRSPDFNAVKALLKTPMVFDGRNLFEPQAMRDAGFEYQAIGRSTQS

Sequences:

>Translated_454_residues
MKITIIGSGYVGLVTGACLAELGNDVFCLDVDQKKIDLLNAGGVPIYEPGLKELIERNRAAGRIQFSTDVAASVAHGDVQ
FIAVGTPPDEDGSADLKYVLAAARNIAQHMTGFKVIVDKSTVPVGTGDKVRAAVGEVLATRGKSDIGFSVVSNPEFLKEG
AAVDDFMRPDRIVLGTYGDNNGLRAKAIMRTLYAPFNRNHERTFYMDVRSAEFTKYAANSMLATRISFMNEMANLADKVG
ADIELVRLGIGSDPRIGYSFLYAGTGYGGSCFPKDVQALVRTAQEYGQTLHVLEAVEAVNDKQKEVLVGKIEDRMGADLT
GRTFAIWGLAFKPNTDDMREAPSRNLIAALLARGARVQVYDPVAMEEARHALGLDLSSEQLERVAFCAGQMDALKDADAL
VIVTEWKAFRSPDFNAVKALLKTPMVFDGRNLFEPQAMRDAGFEYQAIGRSTQS
>Mature_454_residues
MKITIIGSGYVGLVTGACLAELGNDVFCLDVDQKKIDLLNAGGVPIYEPGLKELIERNRAAGRIQFSTDVAASVAHGDVQ
FIAVGTPPDEDGSADLKYVLAAARNIAQHMTGFKVIVDKSTVPVGTGDKVRAAVGEVLATRGKSDIGFSVVSNPEFLKEG
AAVDDFMRPDRIVLGTYGDNNGLRAKAIMRTLYAPFNRNHERTFYMDVRSAEFTKYAANSMLATRISFMNEMANLADKVG
ADIELVRLGIGSDPRIGYSFLYAGTGYGGSCFPKDVQALVRTAQEYGQTLHVLEAVEAVNDKQKEVLVGKIEDRMGADLT
GRTFAIWGLAFKPNTDDMREAPSRNLIAALLARGARVQVYDPVAMEEARHALGLDLSSEQLERVAFCAGQMDALKDADAL
VIVTEWKAFRSPDFNAVKALLKTPMVFDGRNLFEPQAMRDAGFEYQAIGRSTQS

Specific function: Unknown

COG id: COG1004

COG function: function code M; Predicted UDP-glucose 6-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4507813, Length=472, Percent_Identity=35.3813559322034, Blast_Score=270, Evalue=2e-72,
Organism=Homo sapiens, GI296040438, Length=374, Percent_Identity=35.0267379679144, Blast_Score=214, Evalue=1e-55,
Organism=Homo sapiens, GI296040443, Length=325, Percent_Identity=35.0769230769231, Blast_Score=178, Evalue=9e-45,
Organism=Escherichia coli, GI1788340, Length=402, Percent_Identity=27.6119402985075, Blast_Score=147, Evalue=1e-36,
Organism=Escherichia coli, GI48994968, Length=431, Percent_Identity=27.6102088167053, Blast_Score=131, Evalue=9e-32,
Organism=Caenorhabditis elegans, GI17560350, Length=464, Percent_Identity=35.5603448275862, Blast_Score=259, Evalue=3e-69,
Organism=Drosophila melanogaster, GI17136908, Length=468, Percent_Identity=33.974358974359, Blast_Score=253, Evalue=1e-67,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR021157
- InterPro:   IPR016040
- InterPro:   IPR017476
- InterPro:   IPR014027
- InterPro:   IPR014026
- InterPro:   IPR014028
- InterPro:   IPR001732 [H]

Pfam domain/function: PF00984 UDPG_MGDP_dh; PF03720 UDPG_MGDP_dh_C; PF03721 UDPG_MGDP_dh_N [H]

EC number: =1.1.1.22 [H]

Molecular weight: Translated: 49257; Mature: 49257

Theoretical pI: Translated: 5.23; Mature: 5.23

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKITIIGSGYVGLVTGACLAELGNDVFCLDVDQKKIDLLNAGGVPIYEPGLKELIERNRA
CEEEEEECCHHHHHHHHHHHHHCCCEEEEECCCCCEEEEECCCCCCCCHHHHHHHHCCCC
AGRIQFSTDVAASVAHGDVQFIAVGTPPDEDGSADLKYVLAAARNIAQHMTGFKVIVDKS
CCEEEECCCHHHHHCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCEEEEEECC
TVPVGTGDKVRAAVGEVLATRGKSDIGFSVVSNPEFLKEGAAVDDFMRPDRIVLGTYGDN
CCCCCCCCHHHHHHHHHHHHCCCCCCCEEEECCHHHHHCCCCHHHHCCCCEEEEEEECCC
NGLRAKAIMRTLYAPFNRNHERTFYMDVRSAEFTKYAANSMLATRISFMNEMANLADKVG
CCCHHHHHHHHHHCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
ADIELVRLGIGSDPRIGYSFLYAGTGYGGSCFPKDVQALVRTAQEYGQTLHVLEAVEAVN
CCEEEEEECCCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHC
DKQKEVLVGKIEDRMGADLTGRTFAIWGLAFKPNTDDMREAPSRNLIAALLARGARVQVY
CCHHHHHHHHHHHHCCCCCCCCEEEEEEEEECCCCCHHHHCCCHHHHHHHHHCCCEEEEE
DPVAMEEARHALGLDLSSEQLERVAFCAGQMDALKDADALVIVTEWKAFRSPDFNAVKAL
CCHHHHHHHHHHCCCCCHHHHHHHHHHHCCHHHHCCCCEEEEEEECHHHCCCCHHHHHHH
LKTPMVFDGRNLFEPQAMRDAGFEYQAIGRSTQS
HHCCCEECCCCCCCCHHHHHCCCEEEECCCCCCC
>Mature Secondary Structure
MKITIIGSGYVGLVTGACLAELGNDVFCLDVDQKKIDLLNAGGVPIYEPGLKELIERNRA
CEEEEEECCHHHHHHHHHHHHHCCCEEEEECCCCCEEEEECCCCCCCCHHHHHHHHCCCC
AGRIQFSTDVAASVAHGDVQFIAVGTPPDEDGSADLKYVLAAARNIAQHMTGFKVIVDKS
CCEEEECCCHHHHHCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCEEEEEECC
TVPVGTGDKVRAAVGEVLATRGKSDIGFSVVSNPEFLKEGAAVDDFMRPDRIVLGTYGDN
CCCCCCCCHHHHHHHHHHHHCCCCCCCEEEECCHHHHHCCCCHHHHCCCCEEEEEEECCC
NGLRAKAIMRTLYAPFNRNHERTFYMDVRSAEFTKYAANSMLATRISFMNEMANLADKVG
CCCHHHHHHHHHHCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
ADIELVRLGIGSDPRIGYSFLYAGTGYGGSCFPKDVQALVRTAQEYGQTLHVLEAVEAVN
CCEEEEEECCCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHC
DKQKEVLVGKIEDRMGADLTGRTFAIWGLAFKPNTDDMREAPSRNLIAALLARGARVQVY
CCHHHHHHHHHHHHCCCCCCCCEEEEEEEEECCCCCHHHHCCCHHHHHHHHHCCCEEEEE
DPVAMEEARHALGLDLSSEQLERVAFCAGQMDALKDADALVIVTEWKAFRSPDFNAVKAL
CCHHHHHHHHHHCCCCCHHHHHHHHHHHCCHHHHCCCCEEEEEEECHHHCCCCHHHHHHH
LKTPMVFDGRNLFEPQAMRDAGFEYQAIGRSTQS
HHCCCEECCCCCCCCHHHHHCCCEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]