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The map label for this gene is 187927848

Identifier: 187927848

GI number: 187927848

Start: 792647

End: 793432

Strand: Direct

Name: 187927848

Synonym: Rpic_0752

Alternate gene names: NA

Gene position: 792647-793432 (Clockwise)

Preceding gene: 187927847

Following gene: 187927849

Centisome position: 20.1

GC content: 64.76

Gene sequence:

>786_bases
ATGTCTTTTGCCTTGCGCCCCGATGCCGTTGTGCCCGGCGGCGAGATCAGCCAAGCCGAGCGCGCTGTGCGGGTCGACCT
TGCCGCCGCGTACCGACTGGCCGCGCTCAACGGTTGGGACGATCTGGTCTACACCCATCTGTCTGCGTCCGTGCCGGGCG
AGCCTGATCACTTCCTGATCAACGCTTTCGGCCTCGCGTTCGACGAGATCACCGCATCCAACCTGGTCAAGATCAATGGC
CGCGGCCAGCTCGTCGGCGTCTGGCCCGATGCGGCCACGCATCCCTCCGTTAACGTGACCGGTTTCGCATTGCACGCAGC
CGTGCACGCCGCCCGGCCCGACGCGCAGTGCGTGATCCATCTGCATAACACGGCGGGCATTGCCGTGTCTGCGCAGAAGC
ACGGGCTGTTGCCGCTGTCTCAGCATGCGCTGCGGTTTCACCGGCGCATCGCGTATCACGATTACGAAGGCCTTGCGTTC
ACGCCGGAAGAGGGCAGCCGCCTTACCGCATCGTTGGGCAACCGTTTCGCCATGTTGCTGCGCAATCACGGAACGCTGAC
CATCGGCCGTACCGTGGCCGAGGCGCACGTGCTGATGGCCACGCTCATCAAGGCATGCGAGATCCAGATTCACGCGCTTG
CGGGCGGCGAGGTCGTCGCGCCGGCGCCGGAAGTGGCAGAGCGTTCGGCAGAGCAGCTCGAAGATGGCGGCGCCATCGAA
GGCGTGATCGAGTGGCCGGCGCTGTTGCGCAAACTGGATAAAATCGACGCTTCGTATCGCGACTGA

Upstream 100 bases:

>100_bases
GCGCGTGGCCCCGGCGCGTGCGTGATGCGCGGCATGTGAAGGCGCCCACCACGCGGTCGACGCGCCCGTTCTAGAATGCC
TCCTCCATTGGAGGAGCCTC

Downstream 100 bases:

>100_bases
CGCGACTGATACAACCGCCGCGACTATCAGAGCGACGCACCAAACAGGAGACACCATGCCGACTTTCCATATCGAGATGT
TCGAGGGCCGCAGCGTTGAG

Product: aldolase II superfamily protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 261; Mature: 260

Protein sequence:

>261_residues
MSFALRPDAVVPGGEISQAERAVRVDLAAAYRLAALNGWDDLVYTHLSASVPGEPDHFLINAFGLAFDEITASNLVKING
RGQLVGVWPDAATHPSVNVTGFALHAAVHAARPDAQCVIHLHNTAGIAVSAQKHGLLPLSQHALRFHRRIAYHDYEGLAF
TPEEGSRLTASLGNRFAMLLRNHGTLTIGRTVAEAHVLMATLIKACEIQIHALAGGEVVAPAPEVAERSAEQLEDGGAIE
GVIEWPALLRKLDKIDASYRD

Sequences:

>Translated_261_residues
MSFALRPDAVVPGGEISQAERAVRVDLAAAYRLAALNGWDDLVYTHLSASVPGEPDHFLINAFGLAFDEITASNLVKING
RGQLVGVWPDAATHPSVNVTGFALHAAVHAARPDAQCVIHLHNTAGIAVSAQKHGLLPLSQHALRFHRRIAYHDYEGLAF
TPEEGSRLTASLGNRFAMLLRNHGTLTIGRTVAEAHVLMATLIKACEIQIHALAGGEVVAPAPEVAERSAEQLEDGGAIE
GVIEWPALLRKLDKIDASYRD
>Mature_260_residues
SFALRPDAVVPGGEISQAERAVRVDLAAAYRLAALNGWDDLVYTHLSASVPGEPDHFLINAFGLAFDEITASNLVKINGR
GQLVGVWPDAATHPSVNVTGFALHAAVHAARPDAQCVIHLHNTAGIAVSAQKHGLLPLSQHALRFHRRIAYHDYEGLAFT
PEEGSRLTASLGNRFAMLLRNHGTLTIGRTVAEAHVLMATLIKACEIQIHALAGGEVVAPAPEVAERSAEQLEDGGAIEG
VIEWPALLRKLDKIDASYRD

Specific function: Unknown

COG id: COG0235

COG function: function code G; Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldolase class II family [H]

Homologues:

Organism=Homo sapiens, GI29826323, Length=198, Percent_Identity=47.4747474747475, Blast_Score=181, Evalue=8e-46,
Organism=Homo sapiens, GI29826325, Length=198, Percent_Identity=47.4747474747475, Blast_Score=180, Evalue=9e-46,
Organism=Homo sapiens, GI29826319, Length=198, Percent_Identity=47.4747474747475, Blast_Score=180, Evalue=9e-46,
Organism=Homo sapiens, GI29826321, Length=198, Percent_Identity=47.4747474747475, Blast_Score=180, Evalue=9e-46,
Organism=Homo sapiens, GI9943848, Length=209, Percent_Identity=42.5837320574163, Blast_Score=157, Evalue=1e-38,
Organism=Homo sapiens, GI9951927, Length=209, Percent_Identity=42.5837320574163, Blast_Score=157, Evalue=1e-38,
Organism=Homo sapiens, GI62912453, Length=209, Percent_Identity=42.5837320574163, Blast_Score=157, Evalue=1e-38,
Organism=Homo sapiens, GI297307158, Length=204, Percent_Identity=43.1372549019608, Blast_Score=150, Evalue=1e-36,
Organism=Homo sapiens, GI9257192, Length=204, Percent_Identity=43.1372549019608, Blast_Score=150, Evalue=1e-36,
Organism=Homo sapiens, GI9257190, Length=204, Percent_Identity=43.1372549019608, Blast_Score=150, Evalue=2e-36,
Organism=Homo sapiens, GI89276787, Length=204, Percent_Identity=42.6470588235294, Blast_Score=149, Evalue=2e-36,
Organism=Homo sapiens, GI297307160, Length=204, Percent_Identity=42.6470588235294, Blast_Score=149, Evalue=2e-36,
Organism=Caenorhabditis elegans, GI115533216, Length=251, Percent_Identity=36.6533864541833, Blast_Score=162, Evalue=2e-40,
Organism=Caenorhabditis elegans, GI115533218, Length=251, Percent_Identity=36.6533864541833, Blast_Score=162, Evalue=2e-40,
Organism=Caenorhabditis elegans, GI71989550, Length=251, Percent_Identity=32.6693227091633, Blast_Score=138, Evalue=3e-33,
Organism=Caenorhabditis elegans, GI71989555, Length=251, Percent_Identity=32.6693227091633, Blast_Score=138, Evalue=3e-33,
Organism=Caenorhabditis elegans, GI71989544, Length=251, Percent_Identity=32.6693227091633, Blast_Score=138, Evalue=4e-33,
Organism=Caenorhabditis elegans, GI71989560, Length=251, Percent_Identity=32.6693227091633, Blast_Score=137, Evalue=4e-33,
Organism=Caenorhabditis elegans, GI71989541, Length=251, Percent_Identity=32.6693227091633, Blast_Score=137, Evalue=4e-33,
Organism=Drosophila melanogaster, GI281363755, Length=201, Percent_Identity=39.3034825870647, Blast_Score=136, Evalue=1e-32,
Organism=Drosophila melanogaster, GI281363751, Length=201, Percent_Identity=39.3034825870647, Blast_Score=136, Evalue=1e-32,
Organism=Drosophila melanogaster, GI24655690, Length=201, Percent_Identity=39.3034825870647, Blast_Score=136, Evalue=1e-32,
Organism=Drosophila melanogaster, GI24655685, Length=201, Percent_Identity=39.3034825870647, Blast_Score=135, Evalue=2e-32,
Organism=Drosophila melanogaster, GI281363761, Length=201, Percent_Identity=39.3034825870647, Blast_Score=135, Evalue=3e-32,
Organism=Drosophila melanogaster, GI281363759, Length=201, Percent_Identity=39.3034825870647, Blast_Score=135, Evalue=3e-32,
Organism=Drosophila melanogaster, GI281363753, Length=201, Percent_Identity=39.3034825870647, Blast_Score=135, Evalue=3e-32,
Organism=Drosophila melanogaster, GI281363763, Length=201, Percent_Identity=39.3034825870647, Blast_Score=134, Evalue=6e-32,
Organism=Drosophila melanogaster, GI281363757, Length=201, Percent_Identity=39.3034825870647, Blast_Score=134, Evalue=6e-32,
Organism=Drosophila melanogaster, GI17136738, Length=201, Percent_Identity=39.3034825870647, Blast_Score=134, Evalue=6e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001303 [H]

Pfam domain/function: PF00596 Aldolase_II [H]

EC number: NA

Molecular weight: Translated: 27956; Mature: 27825

Theoretical pI: Translated: 6.39; Mature: 6.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFALRPDAVVPGGEISQAERAVRVDLAAAYRLAALNGWDDLVYTHLSASVPGEPDHFLI
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHEEECCCCCCCCEEEE
NAFGLAFDEITASNLVKINGRGQLVGVWPDAATHPSVNVTGFALHAAVHAARPDAQCVIH
EEHHHHHHHCCCCCEEEECCCEEEEEECCCCCCCCCCCEEHHHHHHHHHHCCCCCEEEEE
LHNTAGIAVSAQKHGLLPLSQHALRFHRRIAYHDYEGLAFTPEEGSRLTASLGNRFAMLL
EECCCCEEEECCCCCCCCHHHHHHHHHHHHHEECCCCEEECCCCCCEEEHHHHHHHEEEH
RNHGTLTIGRTVAEAHVLMATLIKACEIQIHALAGGEVVAPAPEVAERSAEQLEDGGAIE
HCCCCEEEHHHHHHHHHHHHHHHHHHEEEEEEEECCCEECCCHHHHHHHHHHHHCCCCEE
GVIEWPALLRKLDKIDASYRD
HHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
SFALRPDAVVPGGEISQAERAVRVDLAAAYRLAALNGWDDLVYTHLSASVPGEPDHFLI
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHEEECCCCCCCCEEEE
NAFGLAFDEITASNLVKINGRGQLVGVWPDAATHPSVNVTGFALHAAVHAARPDAQCVIH
EEHHHHHHHCCCCCEEEECCCEEEEEECCCCCCCCCCCEEHHHHHHHHHHCCCCCEEEEE
LHNTAGIAVSAQKHGLLPLSQHALRFHRRIAYHDYEGLAFTPEEGSRLTASLGNRFAMLL
EECCCCEEEECCCCCCCCHHHHHHHHHHHHHEECCCCEEECCCCCCEEEHHHHHHHEEEH
RNHGTLTIGRTVAEAHVLMATLIKACEIQIHALAGGEVVAPAPEVAERSAEQLEDGGAIE
HCCCCEEEHHHHHHHHHHHHHHHHHHEEEEEEEECCCEECCCHHHHHHHHHHHHCCCCEE
GVIEWPALLRKLDKIDASYRD
HHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11259647 [H]