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The map label for this gene is lrp [H]

Identifier: 187927807

GI number: 187927807

Start: 747171

End: 747698

Strand: Direct

Name: lrp [H]

Synonym: Rpic_0711

Alternate gene names: 187927807

Gene position: 747171-747698 (Clockwise)

Preceding gene: 187927803

Following gene: 187927808

Centisome position: 18.95

GC content: 65.15

Gene sequence:

>528_bases
ATGCAACTCGATACCACCGATCTGCGCATTCTCCAGGTCTTGCAGGAAGACGGCCGCATCAGCAACCAGGACCTGGCCGA
ACGCGTCGCGCTGTCGCCGTCGGCCTGCCTGCGGCGTGTGCGGATGCTGGAAGAGGGCGGCGCCATCACGGGTTACCGGG
CGCAATTGGGCCGGGCGGCACTCGGGCTGGAACTGGAAGCCATCGTGCAGGTGTCGATGCGCCAGGACGTGACGGGCTGG
CACGAGACGTTCATGGCTGCCGTGCAGAGTTGGCCCGAGATCGTGGCCGCTTACATCATCACCGGGGATTGCAACTACAT
CCTGCGCGTGCAGGCGCCCAACCTGCAGCACTACTCGGAATTCATCATCGAGCGGCTGTACAAGACGCCCGGCGTGATGG
ACATCCGCTCGAATATCGTCCTGCGCACCATCAAGGACCGCGACGGCGGTCTGGCGCTGTTGATGGAAGCGCGGGGCGTG
CGCCCGCTCGAGGGCAAGGCGACGGGCAAGGGCGGGAGAGCAAAGTAG

Upstream 100 bases:

>100_bases
GAAATCCGCGCGCAATGGGTTTGCATAATCGTGCGTGTGAGTTCGATGGATTCGCATAAAATGCAACGTACACAGGAAAT
CACGCAAAGAACAACGACAG

Downstream 100 bases:

>100_bases
CAAGTGGCGCCGGACTTTCTGACGAGAATCAATCCCCTACTGAAAGCATGCGCGGATAGTGGCCCTGTGTTGTCGACCGG
AGCGGGCCATGGCCAAGAAG

Product: AsnC family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 175; Mature: 175

Protein sequence:

>175_residues
MQLDTTDLRILQVLQEDGRISNQDLAERVALSPSACLRRVRMLEEGGAITGYRAQLGRAALGLELEAIVQVSMRQDVTGW
HETFMAAVQSWPEIVAAYIITGDCNYILRVQAPNLQHYSEFIIERLYKTPGVMDIRSNIVLRTIKDRDGGLALLMEARGV
RPLEGKATGKGGRAK

Sequences:

>Translated_175_residues
MQLDTTDLRILQVLQEDGRISNQDLAERVALSPSACLRRVRMLEEGGAITGYRAQLGRAALGLELEAIVQVSMRQDVTGW
HETFMAAVQSWPEIVAAYIITGDCNYILRVQAPNLQHYSEFIIERLYKTPGVMDIRSNIVLRTIKDRDGGLALLMEARGV
RPLEGKATGKGGRAK
>Mature_175_residues
MQLDTTDLRILQVLQEDGRISNQDLAERVALSPSACLRRVRMLEEGGAITGYRAQLGRAALGLELEAIVQVSMRQDVTGW
HETFMAAVQSWPEIVAAYIITGDCNYILRVQAPNLQHYSEFIIERLYKTPGVMDIRSNIVLRTIKDRDGGLALLMEARGV
RPLEGKATGKGGRAK

Specific function: Mediates a global response to leucine. Exogenous leucine affects the expression of a number of different operons; lrp mediates this effect for at least some of these operons [H]

COG id: COG1522

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH asnC-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787116, Length=143, Percent_Identity=39.8601398601399, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI87081742, Length=143, Percent_Identity=32.1678321678322, Blast_Score=92, Evalue=2e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011008
- InterPro:   IPR000485
- InterPro:   IPR019885
- InterPro:   IPR019888
- InterPro:   IPR019887
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01037 AsnC_trans_reg [H]

EC number: NA

Molecular weight: Translated: 19438; Mature: 19438

Theoretical pI: Translated: 8.21; Mature: 8.21

Prosite motif: PS00519 HTH_ASNC_1 ; PS50956 HTH_ASNC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQLDTTDLRILQVLQEDGRISNQDLAERVALSPSACLRRVRMLEEGGAITGYRAQLGRAA
CCCCHHHHHHHHHHHHCCCCCCHHHHHHHCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHH
LGLELEAIVQVSMRQDVTGWHETFMAAVQSWPEIVAAYIITGDCNYILRVQAPNLQHYSE
HCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHEEECCCCEEEEEECCCHHHHHH
FIIERLYKTPGVMDIRSNIVLRTIKDRDGGLALLMEARGVRPLEGKATGKGGRAK
HHHHHHHHCCCCEECCCCEEEEEECCCCCCEEEEEECCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MQLDTTDLRILQVLQEDGRISNQDLAERVALSPSACLRRVRMLEEGGAITGYRAQLGRAA
CCCCHHHHHHHHHHHHCCCCCCHHHHHHHCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHH
LGLELEAIVQVSMRQDVTGWHETFMAAVQSWPEIVAAYIITGDCNYILRVQAPNLQHYSE
HCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHEEECCCCEEEEEECCCHHHHHH
FIIERLYKTPGVMDIRSNIVLRTIKDRDGGLALLMEARGVRPLEGKATGKGGRAK
HHHHHHHHCCCCEECCCCEEEEEECCCCCCEEEEEECCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11157937; 11481430 [H]