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The map label for this gene is ahpC [C]

Identifier: 187927800

GI number: 187927800

Start: 739505

End: 740143

Strand: Direct

Name: ahpC [C]

Synonym: Rpic_0704

Alternate gene names: 187927800

Gene position: 739505-740143 (Clockwise)

Preceding gene: 187927796

Following gene: 187927803

Centisome position: 18.76

GC content: 56.49

Gene sequence:

>639_bases
ATGTCTCTACGTTTGGGCGATATCGCCCCTGATTTCGAGCAGGATTCCAGTGAAGGCCGCATCAAGTTTCATGAGTGGCT
GGGCAATAGCTGGGGCGTGCTTTTTTCGCACCCGGCCGATTACACGCCGGTCTGCACCACCGAACTGGGCCTGACCGCCA
AGCTGAAGGACGAATTTGCCAAGCGCAATGTCAAGGCGATTGCGCTGTCGGTCGACTCGGTTGAGTCGCACAAGGGCTGG
ATCAACGATATCAACGAGACGCAGAACACCAGCGTCAACTTCCCGATCATTGCCGACCCCGATCGCAAGGTCTCGCAGCT
GTACGACATGATTCATCCGAATGCGAGCGAGACGTTCACCGTGCGTTCGTTGTTCGTGATCGATCCGAACAAGAAGATTC
GCCTGACGATTACGTATCCGGCATCGACGGGGCGTAATTTCAATGAAGTCCTGCGCGTGATCGACTCGCTGCAGTTGACC
GAGTACCACAGCGTGGCCACGCCGGGTAACTGGCAGGACGGCGATGACGTGGTCATCGTGCCCTCGCTGAAGGATGAGGA
AGTCATCAAGCAGAAATTTCCGAAGGGCTACAAGGCGTTGCGTCCGTATCTGCGCCTGACGCCGCAGCCCAATAAGTAA

Upstream 100 bases:

>100_bases
GCGCCTAATGACGAAAAGTGATGTTGTTGTGAATTTATAGTCGTTTTGGTTGGATGGCAATCTGGCTATAGTGGTTCCCA
ATCTGTGTATGGAGGACACG

Downstream 100 bases:

>100_bases
CCGTCTCCTTGGTAGTGTGATTGCCGCCCGGCCTTGTGCCGGGCGTTTTTTGCGTTGGAGCCGGCTCAGAATCCTAGGCA
AAACAAAAACCGGCCAGCCC

Product: Peroxidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 212; Mature: 211

Protein sequence:

>212_residues
MSLRLGDIAPDFEQDSSEGRIKFHEWLGNSWGVLFSHPADYTPVCTTELGLTAKLKDEFAKRNVKAIALSVDSVESHKGW
INDINETQNTSVNFPIIADPDRKVSQLYDMIHPNASETFTVRSLFVIDPNKKIRLTITYPASTGRNFNEVLRVIDSLQLT
EYHSVATPGNWQDGDDVVIVPSLKDEEVIKQKFPKGYKALRPYLRLTPQPNK

Sequences:

>Translated_212_residues
MSLRLGDIAPDFEQDSSEGRIKFHEWLGNSWGVLFSHPADYTPVCTTELGLTAKLKDEFAKRNVKAIALSVDSVESHKGW
INDINETQNTSVNFPIIADPDRKVSQLYDMIHPNASETFTVRSLFVIDPNKKIRLTITYPASTGRNFNEVLRVIDSLQLT
EYHSVATPGNWQDGDDVVIVPSLKDEEVIKQKFPKGYKALRPYLRLTPQPNK
>Mature_211_residues
SLRLGDIAPDFEQDSSEGRIKFHEWLGNSWGVLFSHPADYTPVCTTELGLTAKLKDEFAKRNVKAIALSVDSVESHKGWI
NDINETQNTSVNFPIIADPDRKVSQLYDMIHPNASETFTVRSLFVIDPNKKIRLTITYPASTGRNFNEVLRVIDSLQLTE
YHSVATPGNWQDGDDVVIVPSLKDEEVIKQKFPKGYKALRPYLRLTPQPNK

Specific function: Directly Reduces Organic Hydroperoxides In Its Reduced Dithiol Form. [C]

COG id: COG0450

COG function: function code O; Peroxiredoxin

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Homo sapiens, GI4758638, Length=222, Percent_Identity=53.6036036036036, Blast_Score=231, Evalue=4e-61,
Organism=Homo sapiens, GI4505591, Length=181, Percent_Identity=30.3867403314917, Blast_Score=97, Evalue=9e-21,
Organism=Homo sapiens, GI32455266, Length=181, Percent_Identity=30.3867403314917, Blast_Score=97, Evalue=9e-21,
Organism=Homo sapiens, GI32455264, Length=181, Percent_Identity=30.3867403314917, Blast_Score=97, Evalue=9e-21,
Organism=Homo sapiens, GI32189392, Length=189, Percent_Identity=30.6878306878307, Blast_Score=96, Evalue=2e-20,
Organism=Homo sapiens, GI32483377, Length=140, Percent_Identity=32.8571428571429, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI5802974, Length=151, Percent_Identity=33.112582781457, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI5453549, Length=148, Percent_Identity=29.7297297297297, Blast_Score=82, Evalue=4e-16,
Organism=Escherichia coli, GI1786822, Length=154, Percent_Identity=31.8181818181818, Blast_Score=79, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI25153706, Length=200, Percent_Identity=43, Blast_Score=167, Evalue=5e-42,
Organism=Caenorhabditis elegans, GI193204376, Length=188, Percent_Identity=31.3829787234043, Blast_Score=95, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI32565831, Length=188, Percent_Identity=31.3829787234043, Blast_Score=95, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17554494, Length=144, Percent_Identity=29.1666666666667, Blast_Score=86, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6319407, Length=212, Percent_Identity=55.6603773584906, Blast_Score=227, Evalue=1e-60,
Organism=Saccharomyces cerevisiae, GI6323613, Length=154, Percent_Identity=29.8701298701299, Blast_Score=70, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6320661, Length=156, Percent_Identity=30.1282051282051, Blast_Score=70, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24581278, Length=219, Percent_Identity=50.6849315068493, Blast_Score=224, Evalue=3e-59,
Organism=Drosophila melanogaster, GI24652434, Length=203, Percent_Identity=51.7241379310345, Blast_Score=203, Evalue=9e-53,
Organism=Drosophila melanogaster, GI24652436, Length=203, Percent_Identity=51.7241379310345, Blast_Score=202, Evalue=1e-52,
Organism=Drosophila melanogaster, GI17975518, Length=203, Percent_Identity=51.7241379310345, Blast_Score=202, Evalue=1e-52,
Organism=Drosophila melanogaster, GI17738015, Length=175, Percent_Identity=33.1428571428571, Blast_Score=95, Evalue=4e-20,
Organism=Drosophila melanogaster, GI17157991, Length=168, Percent_Identity=30.952380952381, Blast_Score=89, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24641739, Length=168, Percent_Identity=30.952380952381, Blast_Score=89, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24656348, Length=176, Percent_Identity=28.9772727272727, Blast_Score=81, Evalue=4e-16,
Organism=Drosophila melanogaster, GI17864676, Length=176, Percent_Identity=28.9772727272727, Blast_Score=81, Evalue=4e-16,
Organism=Drosophila melanogaster, GI21357347, Length=193, Percent_Identity=26.4248704663212, Blast_Score=80, Evalue=1e-15,

Paralogues:

None

Copy number: 300 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2250 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 6040 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1580 Molecules/Cell In: Stationary-Phase

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000866
- InterPro:   IPR019479
- InterPro:   IPR022915
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF10417 1-cysPrx_C; PF00578 AhpC-TSA [H]

EC number: =1.11.1.15 [H]

Molecular weight: Translated: 23987; Mature: 23856

Theoretical pI: Translated: 6.36; Mature: 6.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLRLGDIAPDFEQDSSEGRIKFHEWLGNSWGVLFSHPADYTPVCTTELGLTAKLKDEFA
CCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCEEEECCCCCCCEEECCCCCCHHHHHHHH
KRNVKAIALSVDSVESHKGWINDINETQNTSVNFPIIADPDRKVSQLYDMIHPNASETFT
HCCEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCEEECCCHHHHHHHHHHCCCCCCEEE
VRSLFVIDPNKKIRLTITYPASTGRNFNEVLRVIDSLQLTEYHSVATPGNWQDGDDVVIV
EEEEEEECCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEE
PSLKDEEVIKQKFPKGYKALRPYLRLTPQPNK
CCCCCHHHHHHHCCCCHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
SLRLGDIAPDFEQDSSEGRIKFHEWLGNSWGVLFSHPADYTPVCTTELGLTAKLKDEFA
CCCCCCCCCCCCCCCCCCCEEEEECCCCCCCEEEECCCCCCCEEECCCCCCHHHHHHHH
KRNVKAIALSVDSVESHKGWINDINETQNTSVNFPIIADPDRKVSQLYDMIHPNASETFT
HCCEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCEEECCCHHHHHHHHHHCCCCCCEEE
VRSLFVIDPNKKIRLTITYPASTGRNFNEVLRVIDSLQLTEYHSVATPGNWQDGDDVVIV
EEEEEEECCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEE
PSLKDEEVIKQKFPKGYKALRPYLRLTPQPNK
CCCCCHHHHHHHCCCCHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]