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The map label for this gene is kdgK [H]

Identifier: 187927786

GI number: 187927786

Start: 727961

End: 728950

Strand: Direct

Name: kdgK [H]

Synonym: Rpic_0690

Alternate gene names: 187927786

Gene position: 727961-728950 (Clockwise)

Preceding gene: 187927785

Following gene: 187927787

Centisome position: 18.46

GC content: 65.15

Gene sequence:

>990_bases
ATGTCACATACGTTGGATGTCATCACCTACGGCGAAGCCATGGCGATGTTCGTGGCGACGGCGCCCGGGCCGCTCGCGCA
GGCAACGCAGTTCACCAAGCGGATTGCGGGTGCCGATCTGAATGTGGCCATCGGCTTGAGTCGCCTCGGTTTTCGCGTCG
GCTATGTGAGCCGGGTGGGGCAGGATTCGTTTGGCGAGTACGTGCTGGAAACGCTGGCGCGCGAACGGATCGATGTCTCA
TGCGTGGCGGTGGACCCGCAATATCCGACTGGCTTCCAGCTGAAGTCGCGGGCCGACGACGGCAGTGACCCGCGTGTGGA
GTACTTCCGCAAGGGCTCGGCCGCCAGCCGGCTCTCGTGCGACGACTATGTCGCCGACTACGTGCTTGGCGCACGCCATC
TGCATCTGACGGGCGTGGCCCCCGCAATTTCAGCGTCGTCGTGTGAACTGGCGTTCCACCTTGCGCGAGAGATGCGTGCG
GCCGGGGGTTCGATCTCCTTCGATCCGAACCTGCGCCCAACGCTGTGGCCGTCCGCCGCGGAGATGGTAAGCACGCTCAA
CGCGCTGGCGTCGCTTTCCGATTGGGTGCTGCCCGGCTTGGCCGAGGGGCAGCAACTGACCGGCTATGACACCCCGGCCG
ATATCGCGCGCTTCTATCTCGATCGAGGTGCGCGAGGTGTGGCCATCAAGCTGGGTGCAGCCGGTGCTTATTACCGGACC
GCCGACGGAGCAGAAGGCATCGCCGACGGCGTGCGTGTAGCGCGCGTCGTCGACACAGTGGGCGCGGGCGACGGCTTTGC
AGTGGGCGTTGTCAGCGCGCTGCTTGAAGGGCTGTCGCCCGATCTGGCTGTTGCGCGCGGCAACCGTATTGGCGCACTGG
CGATCCAGGTGATCGGAGATTCAGAAGGCCTGCCGACGCGCGCCGCGCTCGAGGTGCTTGAACAAACGGCCCGCATGGCA
TGCGAGCCGGAACCCATTTCCAACGTGTAA

Upstream 100 bases:

>100_bases
AATTTCCGTTCGACGCGGTCGATCCTGTCGCCGATGCCCATCAACACGTCATGTGGCTCAAGGCCGCCTGACGGTGACGC
GACATCGAAGGAGCTTACGC

Downstream 100 bases:

>100_bases
CGCAGCGCTTCGACTGCCGCCCGTCACGGGCAACGCAAACCATCAAAGGAGACACGACCATGGCAACGCAACTGGCTGCG
CGGCGCTGGTGGATGATCAT

Product: PfkB domain-containing protein

Products: NA

Alternate protein names: 2-keto-3-deoxygluconokinase; 3-deoxy-2-oxo-D-gluconate kinase; KDG kinase [H]

Number of amino acids: Translated: 329; Mature: 328

Protein sequence:

>329_residues
MSHTLDVITYGEAMAMFVATAPGPLAQATQFTKRIAGADLNVAIGLSRLGFRVGYVSRVGQDSFGEYVLETLARERIDVS
CVAVDPQYPTGFQLKSRADDGSDPRVEYFRKGSAASRLSCDDYVADYVLGARHLHLTGVAPAISASSCELAFHLAREMRA
AGGSISFDPNLRPTLWPSAAEMVSTLNALASLSDWVLPGLAEGQQLTGYDTPADIARFYLDRGARGVAIKLGAAGAYYRT
ADGAEGIADGVRVARVVDTVGAGDGFAVGVVSALLEGLSPDLAVARGNRIGALAIQVIGDSEGLPTRAALEVLEQTARMA
CEPEPISNV

Sequences:

>Translated_329_residues
MSHTLDVITYGEAMAMFVATAPGPLAQATQFTKRIAGADLNVAIGLSRLGFRVGYVSRVGQDSFGEYVLETLARERIDVS
CVAVDPQYPTGFQLKSRADDGSDPRVEYFRKGSAASRLSCDDYVADYVLGARHLHLTGVAPAISASSCELAFHLAREMRA
AGGSISFDPNLRPTLWPSAAEMVSTLNALASLSDWVLPGLAEGQQLTGYDTPADIARFYLDRGARGVAIKLGAAGAYYRT
ADGAEGIADGVRVARVVDTVGAGDGFAVGVVSALLEGLSPDLAVARGNRIGALAIQVIGDSEGLPTRAALEVLEQTARMA
CEPEPISNV
>Mature_328_residues
SHTLDVITYGEAMAMFVATAPGPLAQATQFTKRIAGADLNVAIGLSRLGFRVGYVSRVGQDSFGEYVLETLARERIDVSC
VAVDPQYPTGFQLKSRADDGSDPRVEYFRKGSAASRLSCDDYVADYVLGARHLHLTGVAPAISASSCELAFHLAREMRAA
GGSISFDPNLRPTLWPSAAEMVSTLNALASLSDWVLPGLAEGQQLTGYDTPADIARFYLDRGARGVAIKLGAAGAYYRTA
DGAEGIADGVRVARVVDTVGAGDGFAVGVVSALLEGLSPDLAVARGNRIGALAIQVIGDSEGLPTRAALEVLEQTARMAC
EPEPISNV

Specific function: Unknown

COG id: COG0524

COG function: function code G; Sugar kinases, ribokinase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family [H]

Homologues:

Organism=Escherichia coli, GI87081971, Length=279, Percent_Identity=27.2401433691756, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI87082281, Length=282, Percent_Identity=28.3687943262411, Blast_Score=95, Evalue=6e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011611
- InterPro:   IPR002173 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: =2.7.1.45 [H]

Molecular weight: Translated: 34526; Mature: 34395

Theoretical pI: Translated: 4.72; Mature: 4.72

Prosite motif: PS00584 PFKB_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSHTLDVITYGEAMAMFVATAPGPLAQATQFTKRIAGADLNVAIGLSRLGFRVGYVSRVG
CCCEEEEEECCHHHEEEEECCCCCHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHCC
QDSFGEYVLETLARERIDVSCVAVDPQYPTGFQLKSRADDGSDPRVEYFRKGSAASRLSC
CCHHHHHHHHHHHHHCCCEEEEEECCCCCCCCEEECCCCCCCCCHHHHHHCCCCCCCCCH
DDYVADYVLGARHLHLTGVAPAISASSCELAFHLAREMRAAGGSISFDPNLRPTLWPSAA
HHHHHHHHHCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCEECCCCCCCCCCCHH
EMVSTLNALASLSDWVLPGLAEGQQLTGYDTPADIARFYLDRGARGVAIKLGAAGAYYRT
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEEEEECCCCCEEEC
ADGAEGIADGVRVARVVDTVGAGDGFAVGVVSALLEGLSPDLAVARGNRIGALAIQVIGD
CCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCEEEECCCCEEEEEEEEEEC
SEGLPTRAALEVLEQTARMACEPEPISNV
CCCCCHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
SHTLDVITYGEAMAMFVATAPGPLAQATQFTKRIAGADLNVAIGLSRLGFRVGYVSRVG
CCEEEEEECCHHHEEEEECCCCCHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHCC
QDSFGEYVLETLARERIDVSCVAVDPQYPTGFQLKSRADDGSDPRVEYFRKGSAASRLSC
CCHHHHHHHHHHHHHCCCEEEEEECCCCCCCCEEECCCCCCCCCHHHHHHCCCCCCCCCH
DDYVADYVLGARHLHLTGVAPAISASSCELAFHLAREMRAAGGSISFDPNLRPTLWPSAA
HHHHHHHHHCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCEECCCCCCCCCCCHH
EMVSTLNALASLSDWVLPGLAEGQQLTGYDTPADIARFYLDRGARGVAIKLGAAGAYYRT
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEEEEECCCCCEEEC
ADGAEGIADGVRVARVVDTVGAGDGFAVGVVSALLEGLSPDLAVARGNRIGALAIQVIGD
CCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCEEEECCCCEEEEEEEEEEC
SEGLPTRAALEVLEQTARMACEPEPISNV
CCCCCHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8760912; 9384377 [H]