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The map label for this gene is pheS [H]

Identifier: 187935783

GI number: 187935783

Start: 2566770

End: 2567789

Strand: Reverse

Name: pheS [H]

Synonym: CLL_A2473

Alternate gene names: 187935783

Gene position: 2567789-2566770 (Counterclockwise)

Preceding gene: 187934593

Following gene: 187932405

Centisome position: 67.57

GC content: 31.27

Gene sequence:

>1020_bases
ATGAAGGAAAAACTTAAAGAATTACAAGAGCTTGCAATAAAGCAAATTGAAAATTCAATTAAAAGTAATGAATTAGAAGA
AATTAGAGTTAAGTTCTTAGGAAAAAAAGGAGAACTTACTACAATATTAAGAGGTATGGGGGGATTATCTCCAGAAGAAA
GACCTTTAGTAGGAAAATTAGTTAATGAAGCAAAAGCTAAAGTAGAAGAAAAACTAGAGTCAGCAATAAAGAAAATAAAG
GATAAAGAAAAGGCTGAAAAACTTGCAGGTGAAACAATAGATATTTCACTTCCAGGTAAAAAGCAAGTAATAGGAAAAAG
TCATCCTTTAGAATTAACACTTAAAAATATGGAAGATATATTTGTATCAATGGGATTCACAATTGAAGAAGGTCCAGAAG
TTGAATATGATCATTATAATTTTGAAGCATTAAATATACCTAAGAATCATCCAGCAAGAAGTGAGCAAGATACATTATAT
ATAAATGATAATATAGTTCTTAGAACTCAAACTTCACCAGTTCAAGTTAGAACTATGGAAAATCAAAAGCCACCAATTAA
GATGATTTCGCCAGGTAAGGTTTATAGATCAGATTCAGTTGATGCTACACATTCACCTATATTTTATCAAATGGAAGGCC
TAGTTATAGATAAGGGAGTTACCTTTGCAGATTTAAAAGGAACTTTAGAATTATTTGCTAAGAAGATGTTTGGAGATAAA
GTTGAAACTAAGTTCAGACCACATCACTTCCCATTTACAGAACCATCTGCTGAAATGGATGCAACTTGTTTTGTTTGTGG
AGGAGAAGGTTGTAGAGTATGTAAGAATAGTGGATGGATAGAGCTTCTAGGCTGTGGTATGGTTCATCCAAATGTACTTA
GAAACTGTGGAATAGATCCAGAAGTATATAGTGGATTTGCTTTTGGATTTGGTGTTGATAGAATGGTAATGCTTAAATAC
GGAATAGATGATATAAGATTATTATATGAAAGTGATATGAGATTTTTAAACCAATTTTAG

Upstream 100 bases:

>100_bases
ATTTTTATAAGTTTCAATTAGGGTGGTAACGCGGATAATTCGTCCCTTTTATAGGGGGACGATTTTTTTGTACATAAAAA
TGTCTGAAAGGAGAAAAAAC

Downstream 100 bases:

>100_bases
AAAGTAGTTTAAACTTTTTTAACAATATTACTTAATTATATAGCTTGAAAGACATAAAAATACAAGTTCTAAAGAAATTG
ATAATTTGAGAACTTAAGGA

Product: phenylalanyl-tRNA synthetase subunit alpha

Products: NA

Alternate protein names: Phenylalanine--tRNA ligase alpha chain; PheRS [H]

Number of amino acids: Translated: 339; Mature: 339

Protein sequence:

>339_residues
MKEKLKELQELAIKQIENSIKSNELEEIRVKFLGKKGELTTILRGMGGLSPEERPLVGKLVNEAKAKVEEKLESAIKKIK
DKEKAEKLAGETIDISLPGKKQVIGKSHPLELTLKNMEDIFVSMGFTIEEGPEVEYDHYNFEALNIPKNHPARSEQDTLY
INDNIVLRTQTSPVQVRTMENQKPPIKMISPGKVYRSDSVDATHSPIFYQMEGLVIDKGVTFADLKGTLELFAKKMFGDK
VETKFRPHHFPFTEPSAEMDATCFVCGGEGCRVCKNSGWIELLGCGMVHPNVLRNCGIDPEVYSGFAFGFGVDRMVMLKY
GIDDIRLLYESDMRFLNQF

Sequences:

>Translated_339_residues
MKEKLKELQELAIKQIENSIKSNELEEIRVKFLGKKGELTTILRGMGGLSPEERPLVGKLVNEAKAKVEEKLESAIKKIK
DKEKAEKLAGETIDISLPGKKQVIGKSHPLELTLKNMEDIFVSMGFTIEEGPEVEYDHYNFEALNIPKNHPARSEQDTLY
INDNIVLRTQTSPVQVRTMENQKPPIKMISPGKVYRSDSVDATHSPIFYQMEGLVIDKGVTFADLKGTLELFAKKMFGDK
VETKFRPHHFPFTEPSAEMDATCFVCGGEGCRVCKNSGWIELLGCGMVHPNVLRNCGIDPEVYSGFAFGFGVDRMVMLKY
GIDDIRLLYESDMRFLNQF
>Mature_339_residues
MKEKLKELQELAIKQIENSIKSNELEEIRVKFLGKKGELTTILRGMGGLSPEERPLVGKLVNEAKAKVEEKLESAIKKIK
DKEKAEKLAGETIDISLPGKKQVIGKSHPLELTLKNMEDIFVSMGFTIEEGPEVEYDHYNFEALNIPKNHPARSEQDTLY
INDNIVLRTQTSPVQVRTMENQKPPIKMISPGKVYRSDSVDATHSPIFYQMEGLVIDKGVTFADLKGTLELFAKKMFGDK
VETKFRPHHFPFTEPSAEMDATCFVCGGEGCRVCKNSGWIELLGCGMVHPNVLRNCGIDPEVYSGFAFGFGVDRMVMLKY
GIDDIRLLYESDMRFLNQF

Specific function: Unknown

COG id: COG0016

COG function: function code J; Phenylalanyl-tRNA synthetase alpha subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha chain type 1 subfamily [H]

Homologues:

Organism=Homo sapiens, GI5729820, Length=235, Percent_Identity=31.4893617021277, Blast_Score=123, Evalue=2e-28,
Organism=Homo sapiens, GI4758340, Length=271, Percent_Identity=30.6273062730627, Blast_Score=119, Evalue=5e-27,
Organism=Escherichia coli, GI1788007, Length=335, Percent_Identity=48.955223880597, Blast_Score=357, Evalue=1e-100,
Organism=Caenorhabditis elegans, GI32566635, Length=256, Percent_Identity=32.03125, Blast_Score=125, Evalue=4e-29,
Organism=Caenorhabditis elegans, GI32563657, Length=273, Percent_Identity=29.3040293040293, Blast_Score=115, Evalue=3e-26,
Organism=Caenorhabditis elegans, GI17508957, Length=273, Percent_Identity=29.3040293040293, Blast_Score=115, Evalue=4e-26,
Organism=Saccharomyces cerevisiae, GI6321087, Length=268, Percent_Identity=29.8507462686567, Blast_Score=121, Evalue=2e-28,
Organism=Saccharomyces cerevisiae, GI6325304, Length=130, Percent_Identity=33.0769230769231, Blast_Score=79, Evalue=1e-15,
Organism=Drosophila melanogaster, GI18858079, Length=270, Percent_Identity=31.4814814814815, Blast_Score=117, Evalue=8e-27,
Organism=Drosophila melanogaster, GI17137424, Length=302, Percent_Identity=25.4966887417219, Blast_Score=108, Evalue=4e-24,

Paralogues:

None

Copy number: 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006195
- InterPro:   IPR004529
- InterPro:   IPR004188
- InterPro:   IPR022911
- InterPro:   IPR002319
- InterPro:   IPR010978 [H]

Pfam domain/function: PF02912 Phe_tRNA-synt_N; PF01409 tRNA-synt_2d [H]

EC number: =6.1.1.20 [H]

Molecular weight: Translated: 38273; Mature: 38273

Theoretical pI: Translated: 6.20; Mature: 6.20

Prosite motif: PS50862 AA_TRNA_LIGASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKEKLKELQELAIKQIENSIKSNELEEIRVKFLGKKGELTTILRGMGGLSPEERPLVGKL
CHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCHHHHH
VNEAKAKVEEKLESAIKKIKDKEKAEKLAGETIDISLPGKKQVIGKSHPLELTLKNMEDI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHCCCCCCEEEEECHHHHH
FVSMGFTIEEGPEVEYDHYNFEALNIPKNHPARSEQDTLYINDNIVLRTQTSPVQVRTME
HHHCCCEECCCCCCCCCCCCEEEECCCCCCCCCCCCCEEEECCCEEEEECCCCEEEEECC
NQKPPIKMISPGKVYRSDSVDATHSPIFYQMEGLVIDKGVTFADLKGTLELFAKKMFGDK
CCCCCEEEECCCCEECCCCCCCCCCCEEEEECCEEEECCCEEEHHHHHHHHHHHHHHCCH
VETKFRPHHFPFTEPSAEMDATCFVCGGEGCRVCKNSGWIELLGCGMVHPNVLRNCGIDP
HHCCCCCCCCCCCCCCCCCCCEEEEECCCCCEEECCCCEEEEEECCCCCHHHHHHCCCCH
EVYSGFAFGFGVDRMVMLKYGIDDIRLLYESDMRFLNQF
HHHCCCCCCCCCCCEEHHHHCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKEKLKELQELAIKQIENSIKSNELEEIRVKFLGKKGELTTILRGMGGLSPEERPLVGKL
CHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCHHHHH
VNEAKAKVEEKLESAIKKIKDKEKAEKLAGETIDISLPGKKQVIGKSHPLELTLKNMEDI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHCCCCCCEEEEECHHHHH
FVSMGFTIEEGPEVEYDHYNFEALNIPKNHPARSEQDTLYINDNIVLRTQTSPVQVRTME
HHHCCCEECCCCCCCCCCCCEEEECCCCCCCCCCCCCEEEECCCEEEEECCCCEEEEECC
NQKPPIKMISPGKVYRSDSVDATHSPIFYQMEGLVIDKGVTFADLKGTLELFAKKMFGDK
CCCCCEEEECCCCEECCCCCCCCCCCEEEEECCEEEECCCEEEHHHHHHHHHHHHHHCCH
VETKFRPHHFPFTEPSAEMDATCFVCGGEGCRVCKNSGWIELLGCGMVHPNVLRNCGIDP
HHCCCCCCCCCCCCCCCCCCCEEEEECCCCCEEECCCCEEEEEECCCCCHHHHHHCCCCH
EVYSGFAFGFGVDRMVMLKYGIDDIRLLYESDMRFLNQF
HHHCCCCCCCCCCCEEHHHHCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA