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The map label for this gene is ccdA [H]

Identifier: 187935626

GI number: 187935626

Start: 2885864

End: 2887165

Strand: Reverse

Name: ccdA [H]

Synonym: CLL_A2806

Alternate gene names: 187935626

Gene position: 2887165-2885864 (Counterclockwise)

Preceding gene: 187932876

Following gene: 187932755

Centisome position: 75.97

GC content: 26.88

Gene sequence:

>1302_bases
GTGTTTGAAGGAATAACCTCTGTAAGTAATGTAAGTTATTTATTAGTATTTTTTGAGGGGATAGTTTCATTTCTATCCCC
TTGTGTATTACCTTTAATACCACTTTACATTGGATATTTAGCGGGAAATGCTAAAAAACAAAATAATGATGGTACATATA
CTTATGAAAGAAAAAAAGTATTATTTCACACTATATTTTTTGTACTAGGAATTTCAACAGCTTTTTTCATACTAGGAATT
TCATTTACCACAATAGGAACATTTCTTAATAATAATAAAATGATTTTCACTAAAATTAGTGGAATTATTATAATTATTTT
AGGTTTATTCCAAATGGGAATTTTTGAATTTAAATTTTTGCAAAGAGAACGTAAACTAAAAATAAACTTAAATGGAAAAA
AGGTAAATCCTTTAATAGCTTATATAATGGGATTTACATTTAGCTTTGCATGGACACCTTGTGTTGGTCCAGCATTATCA
TCAGTTTTAATTCTTGCATCAAGTGCTAAAGATGTAGCTATTGGAAATTTATTGGTTTTAATATATTGCTTAGGCTTTGT
AATACCATTTTTAATATTAGGTCTTTTTACAACTCAAGCTTTAAATTTTATAAAAAATAATAAAAATGTTATGAAGTATA
CAATAAAAATAGGTGGAGTCCTAATGATAATTATGGGAGTAATGACTTTTACAGGATGGTTAAATAATGTTACAGGTTAT
TTAAATCAAGTAGGAAGTAATGAAAATACTAAATTAACCTCAGAAGAAAAAGAGGAAATTAAAAGAGAAGAACAATATAT
TAAAGAGTCAGAAGAAAGAAATAATTCTAATAGTACAAATTCAAGTAATGAAAATATAGAAAAGGAACCTTTGCAACCAT
CATTTGATTTTACGTTAAAGGATCAGTATGGAAGTGTTCATAAATTATCTGATTATAAAGGTAAAACTGTATTTTTAAAT
TTCTGGGCAACATGGTGTCCGCCATGTCGTATGGAGATGCCTCATATAGAAGAGTTATATAAAGAATTTAATTATAATAA
AGATGATATTATTATCTTAGGAGTGGCTCAACCTGGAGGAGAAGAAAAAGATAAAGATGGAATAAAACAGTTTTTAAATG
ATCAGGGATTTACATTTCCAGTAGTTTTTGATGAGAGCGGTGAGGTATTTAATAATTACAGAATAATGTCTTTACCAACC
ACTTTTATGATAAATAAAGATGGAGATATTTATGGATATGTAAGTGGTGCTTTAAGCAAGGATCAAATGAAAAGTATAAT
AAATGAAACTAAAGAAAAATAG

Upstream 100 bases:

>100_bases
CCTACAATGATAATATTCAAAGATGGAAAAGCAGTAGAAAATTTAACTGGATTTATGCCAAAAGAAAATATAACAAATAA
ATTAAAGGCTCATTTATAAA

Downstream 100 bases:

>100_bases
AAAATAAAAATTAAAAAAAATCACTTGAGATTGATATGCTCCCTTTATAGTAGACAGTTAAAATAATAAAACTGTAACTA
TAGAGGGAGCATTTTTAATT

Product: cytochrome C biogenesis protein transmembrane region family

Products: DsbDoxidized; DsbGreduced [C]

Alternate protein names: NA

Number of amino acids: Translated: 433; Mature: 433

Protein sequence:

>433_residues
MFEGITSVSNVSYLLVFFEGIVSFLSPCVLPLIPLYIGYLAGNAKKQNNDGTYTYERKKVLFHTIFFVLGISTAFFILGI
SFTTIGTFLNNNKMIFTKISGIIIIILGLFQMGIFEFKFLQRERKLKINLNGKKVNPLIAYIMGFTFSFAWTPCVGPALS
SVLILASSAKDVAIGNLLVLIYCLGFVIPFLILGLFTTQALNFIKNNKNVMKYTIKIGGVLMIIMGVMTFTGWLNNVTGY
LNQVGSNENTKLTSEEKEEIKREEQYIKESEERNNSNSTNSSNENIEKEPLQPSFDFTLKDQYGSVHKLSDYKGKTVFLN
FWATWCPPCRMEMPHIEELYKEFNYNKDDIIILGVAQPGGEEKDKDGIKQFLNDQGFTFPVVFDESGEVFNNYRIMSLPT
TFMINKDGDIYGYVSGALSKDQMKSIINETKEK

Sequences:

>Translated_433_residues
MFEGITSVSNVSYLLVFFEGIVSFLSPCVLPLIPLYIGYLAGNAKKQNNDGTYTYERKKVLFHTIFFVLGISTAFFILGI
SFTTIGTFLNNNKMIFTKISGIIIIILGLFQMGIFEFKFLQRERKLKINLNGKKVNPLIAYIMGFTFSFAWTPCVGPALS
SVLILASSAKDVAIGNLLVLIYCLGFVIPFLILGLFTTQALNFIKNNKNVMKYTIKIGGVLMIIMGVMTFTGWLNNVTGY
LNQVGSNENTKLTSEEKEEIKREEQYIKESEERNNSNSTNSSNENIEKEPLQPSFDFTLKDQYGSVHKLSDYKGKTVFLN
FWATWCPPCRMEMPHIEELYKEFNYNKDDIIILGVAQPGGEEKDKDGIKQFLNDQGFTFPVVFDESGEVFNNYRIMSLPT
TFMINKDGDIYGYVSGALSKDQMKSIINETKEK
>Mature_433_residues
MFEGITSVSNVSYLLVFFEGIVSFLSPCVLPLIPLYIGYLAGNAKKQNNDGTYTYERKKVLFHTIFFVLGISTAFFILGI
SFTTIGTFLNNNKMIFTKISGIIIIILGLFQMGIFEFKFLQRERKLKINLNGKKVNPLIAYIMGFTFSFAWTPCVGPALS
SVLILASSAKDVAIGNLLVLIYCLGFVIPFLILGLFTTQALNFIKNNKNVMKYTIKIGGVLMIIMGVMTFTGWLNNVTGY
LNQVGSNENTKLTSEEKEEIKREEQYIKESEERNNSNSTNSSNENIEKEPLQPSFDFTLKDQYGSVHKLSDYKGKTVFLN
FWATWCPPCRMEMPHIEELYKEFNYNKDDIIILGVAQPGGEEKDKDGIKQFLNDQGFTFPVVFDESGEVFNNYRIMSLPT
TFMINKDGDIYGYVSGALSKDQMKSIINETKEK

Specific function: Required for cytochrome c synthesis and stage V of sporulation. Might transfer reducing equivalents across the cytoplasmic membrane, promoting efficient disulfide bond isomerization of proteins localized on the outer surface of the membrane or in the spor

COG id: COG0785

COG function: function code O; Cytochrome c biogenesis protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DsbD family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003834 [H]

Pfam domain/function: PF02683 DsbD [H]

EC number: 1.8.1.8 [C]

Molecular weight: Translated: 49017; Mature: 49017

Theoretical pI: Translated: 7.33; Mature: 7.33

Prosite motif: PS00194 THIOREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHCCC
>Mature Secondary Structure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HHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DsbGoxidized; DsbDreduced/thiol:disulfide reductase [C]

Specific reaction: DsbDreduced/thiol:disulfide reductase + DsbCoxidized = DsbDoxidized + DsbCreduced DsbGoxidized + DsbDreduced/thiol:disulfide reductase = DsbGreduced + DsbDoxidized [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]