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The map label for this gene is bceS [H]

Identifier: 187935385

GI number: 187935385

Start: 3206966

End: 3207982

Strand: Reverse

Name: bceS [H]

Synonym: CLL_A3098

Alternate gene names: 187935385

Gene position: 3207982-3206966 (Counterclockwise)

Preceding gene: 187933023

Following gene: 187935618

Centisome position: 84.41

GC content: 23.11

Gene sequence:

>1017_bases
ATGAAGAGAGAATCTATATTATTTATGATATATTTGTACATTAAAGAAAAAATAAAGATTATTGTATCATTTTTAATATT
TATACTTATATTTTTCAATGTATATCTTTTATATCATGTATCATTAGAACCAGTTTTATATGCTAGCTTATTAACTTGTA
CATTAGCTTTTTTATTTAGTGTATATGATTTTTATAAATTCTATAATAAGCATGTGTATCTATGTGATATTCTTAATGGG
GTAGAAGAAAAGTTAGATAATTTACCTGAAAATAAGAGTTTAATAGAAAAAGATTATCAGAGTATTATTATATCTCTACA
TAAAAATACTCTAGAACTAGAACATAAAGTTAACAGCAATTATAGTGAAATGATAGATTATTATACAATGTGGGTTCACC
AAATAAAGACACCGATTTCTGCATTATATATGATTTTGCAATCTATGGATTCAAGTGAATATAAGAAAATTATGAATCAA
GAATTATTTAAAATAGAGGAATATGTTGAAATGGTACTCAATTATCTTAGATTAGAAAGTATGTCAGATGATTTACGTTT
GGAGGAGTATTGTCTTAATGAGATTGTTCATGACGTGGTAAAAAAATATGCAGTTATATTTATAAATAAAAAAATTTCAT
TAGATTTAGAAGAATTAGATTATAAAATGATAACAGATAAAAAATGGATTAATTTTGTATTAGAACAAATTTTATCTAAT
GCATTAAAGTATACTAATAATGGTAAAATCTCTGTTTATATGGATAAAAAAAGAAAAGATACTTTAATAATTAAAGATAC
TGGGATAGGAATAAAAAAGGAAGATATATTTAGAGTATTTGAAAGAGGATTTACAGGATATAATGGTAGAATGAATAAGA
AATCAACGGGGATAGGGTTATATTTATGTAAGGAGATTTTAAATAATCTTTCGAATAAAATATTTATTACCTCTGAAGTA
GGAAAAGGAACAGAAGTGGCTATTGATTTTTCAAGAAAAAACATTGAAATATACTAA

Upstream 100 bases:

>100_bases
CTGTTAATGTTACTAGACTTAGAAGAAAGTTAGATGACATAAATCTTAAAAATTTTATTAAGACTAAAAAAGGAATCGGA
TATATAGTGGGGGATTAATT

Downstream 100 bases:

>100_bases
CCTTACACAGATGTAAGATTAAGAGGAGAAATGTAAGTCAAGATTAAGGCAGAGCATTTCTTTTTTTATTATACTTAATT
TGTAATAAGATACATCAAAA

Product: integral membrane sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 338; Mature: 338

Protein sequence:

>338_residues
MKRESILFMIYLYIKEKIKIIVSFLIFILIFFNVYLLYHVSLEPVLYASLLTCTLAFLFSVYDFYKFYNKHVYLCDILNG
VEEKLDNLPENKSLIEKDYQSIIISLHKNTLELEHKVNSNYSEMIDYYTMWVHQIKTPISALYMILQSMDSSEYKKIMNQ
ELFKIEEYVEMVLNYLRLESMSDDLRLEEYCLNEIVHDVVKKYAVIFINKKISLDLEELDYKMITDKKWINFVLEQILSN
ALKYTNNGKISVYMDKKRKDTLIIKDTGIGIKKEDIFRVFERGFTGYNGRMNKKSTGIGLYLCKEILNNLSNKIFITSEV
GKGTEVAIDFSRKNIEIY

Sequences:

>Translated_338_residues
MKRESILFMIYLYIKEKIKIIVSFLIFILIFFNVYLLYHVSLEPVLYASLLTCTLAFLFSVYDFYKFYNKHVYLCDILNG
VEEKLDNLPENKSLIEKDYQSIIISLHKNTLELEHKVNSNYSEMIDYYTMWVHQIKTPISALYMILQSMDSSEYKKIMNQ
ELFKIEEYVEMVLNYLRLESMSDDLRLEEYCLNEIVHDVVKKYAVIFINKKISLDLEELDYKMITDKKWINFVLEQILSN
ALKYTNNGKISVYMDKKRKDTLIIKDTGIGIKKEDIFRVFERGFTGYNGRMNKKSTGIGLYLCKEILNNLSNKIFITSEV
GKGTEVAIDFSRKNIEIY
>Mature_338_residues
MKRESILFMIYLYIKEKIKIIVSFLIFILIFFNVYLLYHVSLEPVLYASLLTCTLAFLFSVYDFYKFYNKHVYLCDILNG
VEEKLDNLPENKSLIEKDYQSIIISLHKNTLELEHKVNSNYSEMIDYYTMWVHQIKTPISALYMILQSMDSSEYKKIMNQ
ELFKIEEYVEMVLNYLRLESMSDDLRLEEYCLNEIVHDVVKKYAVIFINKKISLDLEELDYKMITDKKWINFVLEQILSN
ALKYTNNGKISVYMDKKRKDTLIIKDTGIGIKKEDIFRVFERGFTGYNGRMNKKSTGIGLYLCKEILNNLSNKIFITSEV
GKGTEVAIDFSRKNIEIY

Specific function: Member of the two-component regulatory system BceS/BceR involved in the regulation of bacitracin resistance. Activates BceR in response to extracellular bacitracin [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI145693157, Length=214, Percent_Identity=23.3644859813084, Blast_Score=76, Evalue=4e-15,
Organism=Escherichia coli, GI1788713, Length=213, Percent_Identity=24.8826291079812, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI48994928, Length=110, Percent_Identity=30.9090909090909, Blast_Score=65, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467 [H]

Pfam domain/function: PF02518 HATPase_c [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 40067; Mature: 40067

Theoretical pI: Translated: 7.11; Mature: 7.11

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRESILFMIYLYIKEKIKIIVSFLIFILIFFNVYLLYHVSLEPVLYASLLTCTLAFLFS
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
VYDFYKFYNKHVYLCDILNGVEEKLDNLPENKSLIEKDYQSIIISLHKNTLELEHKVNSN
HHHHHHHHCCCEEEHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHCCCC
YSEMIDYYTMWVHQIKTPISALYMILQSMDSSEYKKIMNQELFKIEEYVEMVLNYLRLES
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
MSDDLRLEEYCLNEIVHDVVKKYAVIFINKKISLDLEELDYKMITDKKWINFVLEQILSN
CCCHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCHHHCCHHHHCHHHHHHHHHHHHHHH
ALKYTNNGKISVYMDKKRKDTLIIKDTGIGIKKEDIFRVFERGFTGYNGRMNKKSTGIGL
HHHCCCCCEEEEEEECCCCCEEEEEECCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCHHH
YLCKEILNNLSNKIFITSEVGKGTEVAIDFSRKNIEIY
HHHHHHHHHCCCEEEEEECCCCCCEEEEEECCCCEEEC
>Mature Secondary Structure
MKRESILFMIYLYIKEKIKIIVSFLIFILIFFNVYLLYHVSLEPVLYASLLTCTLAFLFS
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
VYDFYKFYNKHVYLCDILNGVEEKLDNLPENKSLIEKDYQSIIISLHKNTLELEHKVNSN
HHHHHHHHCCCEEEHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHCCCC
YSEMIDYYTMWVHQIKTPISALYMILQSMDSSEYKKIMNQELFKIEEYVEMVLNYLRLES
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
MSDDLRLEEYCLNEIVHDVVKKYAVIFINKKISLDLEELDYKMITDKKWINFVLEQILSN
CCCHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCHHHCCHHHHCHHHHHHHHHHHHHHH
ALKYTNNGKISVYMDKKRKDTLIIKDTGIGIKKEDIFRVFERGFTGYNGRMNKKSTGIGL
HHHCCCCCEEEEEEECCCCCEEEEEECCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCHHH
YLCKEILNNLSNKIFITSEVGKGTEVAIDFSRKNIEIY
HHHHHHHHHCCCEEEEEECCCCCCEEEEEECCCCEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11058132; 10086842 [H]