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The map label for this gene is rpfG [H]

Identifier: 187935359

GI number: 187935359

Start: 3050390

End: 3051442

Strand: Reverse

Name: rpfG [H]

Synonym: CLL_A2965

Alternate gene names: 187935359

Gene position: 3051442-3050390 (Counterclockwise)

Preceding gene: 187935409

Following gene: 187932466

Centisome position: 80.29

GC content: 23.84

Gene sequence:

>1053_bases
ATGCTTTTAAAAATAGGTGATTTAAAAACTGGAATGGTAATAGGGGAAGACATACAAGAAAATAATAATATATTATTATC
AAAAAATGTTGTTATAAGTGATAAAATTCTTAATAAATTACAAACTTCATATAATATAGAAAAAGTTTGGGTTTATGGAG
AGGATTCATTAGAAAAAGCAGAAAATAGTAAAAAAAATTCAGAAGAAGAATTTAAGAAAGTAGAAATTAAATTAAACGAG
ATATGTAAAGATTTACACGGCGTTTTAGATAACACTGCTGATTTACAAAAAGATTGTCTTAAGGAAATTAGAAAGTTAAT
ATCAGAATTACAAAATGTGATTACAACTCCAAATGTAGTTATAGATAATCTACTTTTTTATGGTAGTGAAAAAGATTCTA
TATATAGGCATAGTTTAAACGTGGCATCTATAAGCTGTTTAATTGGAGATTGGATTGGATTTGAGGAAAACAGAATAAAA
TTATTAATATATTCAGCACTTTTACATGATATCGGTAAATGTAAAATTGATGATACAATAATTAATAAACGTGGTAGATT
AAATTCAAAGGATTTAAAAAAAATCAAAGAACATCCTGTTTTAGGCTATAAGATAATTAAAAAAATTAATTTTTTAGATA
AATCAGTATCTCAATCTGTCTTATTACATCATGAAAGGGAAGATGGTAGTGGTTATCCATTAGGAGTTAAAGGAAACAAA
ATACCTGATTTCGCAAAGGTTATTGCAATAGCAGATGTTTTTGAGGCAATAAATTCTAATAGATGCTATAGAAATAAAAA
ATCTCCATTTGAATCAATACAAATAATTAGGGAAGAAAGCTTTGGAAAGCTAGATTATAATTATTGCAATATATTTTTAA
ATCATATAGTAAATTACTACATTGGTAGAGAAGTTAAATTAAATAATAATAAAGTAGCTAAAATAGTACAAATGAATATT
AATGAGTTAGATAGACCATTCATATTTTTAGAAAATGAATTTTTAGATTTAAAAGACAATAAAGATTTAATAATAGAAGA
ATTTATTTTATAA

Upstream 100 bases:

>100_bases
ATAATTGTAGAATATTATTAAGTATAAGATAAAGTTTACAATAAAATGTTAATATTAGATAAATAATTTAAGTATGGTGA
TTAGGGTGAAAAAAAAGTTA

Downstream 100 bases:

>100_bases
CACTTTATCATACTAAAGGATTGACAAAATTTATTGAATTTGATAAACTTAGCACATAATTTCTTAATTGACAGAGTAGA
TATTTGCGCGTTAAGTGTTA

Product: HD-GYP hydrolase domain containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 350; Mature: 350

Protein sequence:

>350_residues
MLLKIGDLKTGMVIGEDIQENNNILLSKNVVISDKILNKLQTSYNIEKVWVYGEDSLEKAENSKKNSEEEFKKVEIKLNE
ICKDLHGVLDNTADLQKDCLKEIRKLISELQNVITTPNVVIDNLLFYGSEKDSIYRHSLNVASISCLIGDWIGFEENRIK
LLIYSALLHDIGKCKIDDTIINKRGRLNSKDLKKIKEHPVLGYKIIKKINFLDKSVSQSVLLHHEREDGSGYPLGVKGNK
IPDFAKVIAIADVFEAINSNRCYRNKKSPFESIQIIREESFGKLDYNYCNIFLNHIVNYYIGREVKLNNNKVAKIVQMNI
NELDRPFIFLENEFLDLKDNKDLIIEEFIL

Sequences:

>Translated_350_residues
MLLKIGDLKTGMVIGEDIQENNNILLSKNVVISDKILNKLQTSYNIEKVWVYGEDSLEKAENSKKNSEEEFKKVEIKLNE
ICKDLHGVLDNTADLQKDCLKEIRKLISELQNVITTPNVVIDNLLFYGSEKDSIYRHSLNVASISCLIGDWIGFEENRIK
LLIYSALLHDIGKCKIDDTIINKRGRLNSKDLKKIKEHPVLGYKIIKKINFLDKSVSQSVLLHHEREDGSGYPLGVKGNK
IPDFAKVIAIADVFEAINSNRCYRNKKSPFESIQIIREESFGKLDYNYCNIFLNHIVNYYIGREVKLNNNKVAKIVQMNI
NELDRPFIFLENEFLDLKDNKDLIIEEFIL
>Mature_350_residues
MLLKIGDLKTGMVIGEDIQENNNILLSKNVVISDKILNKLQTSYNIEKVWVYGEDSLEKAENSKKNSEEEFKKVEIKLNE
ICKDLHGVLDNTADLQKDCLKEIRKLISELQNVITTPNVVIDNLLFYGSEKDSIYRHSLNVASISCLIGDWIGFEENRIK
LLIYSALLHDIGKCKIDDTIINKRGRLNSKDLKKIKEHPVLGYKIIKKINFLDKSVSQSVLLHHEREDGSGYPLGVKGNK
IPDFAKVIAIADVFEAINSNRCYRNKKSPFESIQIIREESFGKLDYNYCNIFLNHIVNYYIGREVKLNNNKVAKIVQMNI
NELDRPFIFLENEFLDLKDNKDLIIEEFIL

Specific function: Positively regulates the synthesis of extracellular enzymes and extracellular polysaccharides. The cell-cell signaling system encoded by rpf genes is required for full virulence and is implicated in regulation of the formation and dispersal of biofilms [H

COG id: COG2206

COG function: function code T; HD-GYP domain

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR003607
- InterPro:   IPR001789 [H]

Pfam domain/function: PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 40324; Mature: 40324

Theoretical pI: Translated: 6.87; Mature: 6.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLKIGDLKTGMVIGEDIQENNNILLSKNVVISDKILNKLQTSYNIEKVWVYGEDSLEKA
CEEEECCCCCCCEECCCCCCCCCEEEECCEEEHHHHHHHHHHCCCEEEEEEECCHHHHHH
ENSKKNSEEEFKKVEIKLNEICKDLHGVLDNTADLQKDCLKEIRKLISELQNVITTPNVV
HCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
IDNLLFYGSEKDSIYRHSLNVASISCLIGDWIGFEENRIKLLIYSALLHDIGKCKIDDTI
HHHHHHCCCCCCCHHHHCCCHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHCCCEECHHH
INKRGRLNSKDLKKIKEHPVLGYKIIKKINFLDKSVSQSVLLHHEREDGSGYPLGVKGNK
HCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCEECCCCCC
IPDFAKVIAIADVFEAINSNRCYRNKKSPFESIQIIREESFGKLDYNYCNIFLNHIVNYY
CCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
IGREVKLNNNKVAKIVQMNINELDRPFIFLENEFLDLKDNKDLIIEEFIL
CCCEEEECCCCEEEEEEECHHHCCCCEEEEECCEECCCCCCCHHHHHHCC
>Mature Secondary Structure
MLLKIGDLKTGMVIGEDIQENNNILLSKNVVISDKILNKLQTSYNIEKVWVYGEDSLEKA
CEEEECCCCCCCEECCCCCCCCCEEEECCEEEHHHHHHHHHHCCCEEEEEEECCHHHHHH
ENSKKNSEEEFKKVEIKLNEICKDLHGVLDNTADLQKDCLKEIRKLISELQNVITTPNVV
HCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
IDNLLFYGSEKDSIYRHSLNVASISCLIGDWIGFEENRIKLLIYSALLHDIGKCKIDDTI
HHHHHHCCCCCCCHHHHCCCHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHCCCEECHHH
INKRGRLNSKDLKKIKEHPVLGYKIIKKINFLDKSVSQSVLLHHEREDGSGYPLGVKGNK
HCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCEECCCCCC
IPDFAKVIAIADVFEAINSNRCYRNKKSPFESIQIIREESFGKLDYNYCNIFLNHIVNYY
CCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
IGREVKLNNNKVAKIVQMNINELDRPFIFLENEFLDLKDNKDLIIEEFIL
CCCEEEECCCCEEEEEEECHHHCCCCEEEEECCEECCCCCCCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11123673 [H]