Click here to switch to the map view.

The map label for this gene is opuCB [H]

Identifier: 187935334

GI number: 187935334

Start: 3006673

End: 3008244

Strand: Reverse

Name: opuCB [H]

Synonym: CLL_A2925

Alternate gene names: 187935334

Gene position: 3008244-3006673 (Counterclockwise)

Preceding gene: 187932328

Following gene: 187934335

Centisome position: 79.16

GC content: 28.5

Gene sequence:

>1572_bases
ATGATGGGATTTTTAAATTATTTAATGGAAGCTAAGTCTCAAATTTTTATGTTATTGATTGAACATATAAAACTTACTTC
ATTATCTGTAGGATTAGCAATTATAATTGCAATGCCATTAGGAATATGTATAAGTTATATAAAACAAATGAACAAGCCTG
TTATAGCAATTGCTAATATAATTCAAGCAATTCCTAGTATGGCATTATTAGGTTTTGCAATACCATTCTTAGGGATAGGA
ACAACTCCAGCTATTGTAATGGTTGTTTTATATTCACTATTACCAATTATAAAGAACACAAATACAGGAATTAAAAGTAT
AAATCCACAGACACTAGAGGCAGCTAGAGGAATTGGGCTTACAAAGTTTCAAATTTTAGTAAAAGTTCAATTACCATTAG
CGTTACCTGTTATTATGTCAGGGGTTAGAATATCTGCGGTTACAGCAGTGGGACTTATGACAATGGCTGCCTTTATTGGT
GGAGGGGGACTAGGATACTTAGTATTTTCAGGAATAAGAACAGTAAATAATTATCAAATTTTAGCAGGTGCAATTCCAGC
TTGTATATTAGCATTAGCAGTTGATTTCTTATTTGGAATAATTGAAAATTTAGTTACACCTGTAAGTCTTCAAAAGGGAA
ATGCTAAACAAGGAATATCCAAAGCAAAAAAGAACAGAAGACAAAAAAGTATTCTTGCACTTACAGCTTGCATAATATTA
GGAATATTTGTAATAACTAATATATCAACTAATAATAATAGTAAGACAATTACTATTGGAAGTAAGGATTATACAGAACA
AGAGATACTTTGTAATATTTTTTCTGAAGCTATAGAGCAAAATACAGATATTTCTGTTAAACGTAAAAGCGCTCTTGGAG
GAACTCAAATATGTTTTTCTGCTTTAAAGAGTGGAGATATTGATATGTATGTTGATTATAGTGGCACATGTTATGGAGAC
ACATTAAAATATACACCTATATCTGATGTAGAAAAAATTTATGATACTGTTAAGACTGATTTTAAAGATAAGTTTAATAT
TGAAGTATTAAACCAAATGGGATTTAATAATACTTATACTTTAGCAGTTAAGAAAGAGACTGCAGAAAAATATAATTTAA
AAACAATAAGTGATATTGCAAAAGTAGGAGATGAGTTAACAATATCTCCATGCTTAGAATTTCTTAATAGGGAAGATGGA
ATTATTGGATTGAAAAAAACTTATAATTTCAACTTTAAAAATGAAATTGGAATTGATGGAAGTCCTAAATACACAGCATT
AATGAATAATGAAAGTGATGTTATAGATGCATTTTCAACTGATGGATTATTAAAGAAATTTGATTTAACTGTCTTAGAAG
ATGATAAAAATTTCTTTCCACCATATTATGCTATACCGTTAGTTAGAGGAGAAACTTTGGAAAAATATCCTGAAATAACT
CCTATAATTGAAGAAATAGCACCTTTATTAACTAATGAAGTAATGATGGATTTAAATTATCAAGTAGATGAATTAAGAAA
GGATCCAAAAGATGTTGCAAGAGAATTTTTACAAGAAAATAATTTGTTGTAA

Upstream 100 bases:

>100_bases
GTTGTTGATGAAGGTGGATGTTTAAGAGGAATAATAACTAAAAGTAGTTTAGTTACAACACTAAGTCAACAATTTTTAGA
TACTGAGGAGGTGGAATAAA

Downstream 100 bases:

>100_bases
AATTCTTATAAATATATATAATAAAATAGTATATTAAGGAAACAATAAATAAGCCAATGATAGTAATAATATATCATTGG
CTTATGTTATAATTATTTTG

Product: glycine betaine/carnitine/choline transport system permease protein opucb

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 523; Mature: 523

Protein sequence:

>523_residues
MMGFLNYLMEAKSQIFMLLIEHIKLTSLSVGLAIIIAMPLGICISYIKQMNKPVIAIANIIQAIPSMALLGFAIPFLGIG
TTPAIVMVVLYSLLPIIKNTNTGIKSINPQTLEAARGIGLTKFQILVKVQLPLALPVIMSGVRISAVTAVGLMTMAAFIG
GGGLGYLVFSGIRTVNNYQILAGAIPACILALAVDFLFGIIENLVTPVSLQKGNAKQGISKAKKNRRQKSILALTACIIL
GIFVITNISTNNNSKTITIGSKDYTEQEILCNIFSEAIEQNTDISVKRKSALGGTQICFSALKSGDIDMYVDYSGTCYGD
TLKYTPISDVEKIYDTVKTDFKDKFNIEVLNQMGFNNTYTLAVKKETAEKYNLKTISDIAKVGDELTISPCLEFLNREDG
IIGLKKTYNFNFKNEIGIDGSPKYTALMNNESDVIDAFSTDGLLKKFDLTVLEDDKNFFPPYYAIPLVRGETLEKYPEIT
PIIEEIAPLLTNEVMMDLNYQVDELRKDPKDVAREFLQENNLL

Sequences:

>Translated_523_residues
MMGFLNYLMEAKSQIFMLLIEHIKLTSLSVGLAIIIAMPLGICISYIKQMNKPVIAIANIIQAIPSMALLGFAIPFLGIG
TTPAIVMVVLYSLLPIIKNTNTGIKSINPQTLEAARGIGLTKFQILVKVQLPLALPVIMSGVRISAVTAVGLMTMAAFIG
GGGLGYLVFSGIRTVNNYQILAGAIPACILALAVDFLFGIIENLVTPVSLQKGNAKQGISKAKKNRRQKSILALTACIIL
GIFVITNISTNNNSKTITIGSKDYTEQEILCNIFSEAIEQNTDISVKRKSALGGTQICFSALKSGDIDMYVDYSGTCYGD
TLKYTPISDVEKIYDTVKTDFKDKFNIEVLNQMGFNNTYTLAVKKETAEKYNLKTISDIAKVGDELTISPCLEFLNREDG
IIGLKKTYNFNFKNEIGIDGSPKYTALMNNESDVIDAFSTDGLLKKFDLTVLEDDKNFFPPYYAIPLVRGETLEKYPEIT
PIIEEIAPLLTNEVMMDLNYQVDELRKDPKDVAREFLQENNLL
>Mature_523_residues
MMGFLNYLMEAKSQIFMLLIEHIKLTSLSVGLAIIIAMPLGICISYIKQMNKPVIAIANIIQAIPSMALLGFAIPFLGIG
TTPAIVMVVLYSLLPIIKNTNTGIKSINPQTLEAARGIGLTKFQILVKVQLPLALPVIMSGVRISAVTAVGLMTMAAFIG
GGGLGYLVFSGIRTVNNYQILAGAIPACILALAVDFLFGIIENLVTPVSLQKGNAKQGISKAKKNRRQKSILALTACIIL
GIFVITNISTNNNSKTITIGSKDYTEQEILCNIFSEAIEQNTDISVKRKSALGGTQICFSALKSGDIDMYVDYSGTCYGD
TLKYTPISDVEKIYDTVKTDFKDKFNIEVLNQMGFNNTYTLAVKKETAEKYNLKTISDIAKVGDELTISPCLEFLNREDG
IIGLKKTYNFNFKNEIGIDGSPKYTALMNNESDVIDAFSTDGLLKKFDLTVLEDDKNFFPPYYAIPLVRGETLEKYPEIT
PIIEEIAPLLTNEVMMDLNYQVDELRKDPKDVAREFLQENNLL

Specific function: Involved in a high affinity multicomponent binding- protein-dependent transport system for glycine betaine, carnitine and choline; probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG1732

COG function: function code M; Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1788451, Length=203, Percent_Identity=36.4532019704434, Blast_Score=124, Evalue=2e-29,
Organism=Escherichia coli, GI1788449, Length=194, Percent_Identity=34.020618556701, Blast_Score=104, Evalue=1e-23,
Organism=Escherichia coli, GI1788452, Length=278, Percent_Identity=25.5395683453237, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1789033, Length=164, Percent_Identity=34.1463414634146, Blast_Score=92, Evalue=8e-20,
Organism=Escherichia coli, GI87081802, Length=114, Percent_Identity=35.9649122807018, Blast_Score=63, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 57485; Mature: 57485

Theoretical pI: Translated: 5.40; Mature: 5.40

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMGFLNYLMEAKSQIFMLLIEHIKLTSLSVGLAIIIAMPLGICISYIKQMNKPVIAIANI
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
IQAIPSMALLGFAIPFLGIGTTPAIVMVVLYSLLPIIKNTNTGIKSINPQTLEAARGIGL
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHCCCCC
TKFQILVKVQLPLALPVIMSGVRISAVTAVGLMTMAAFIGGGGLGYLVFSGIRTVNNYQI
EEEEEEEEEECCHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCHH
LAGAIPACILALAVDFLFGIIENLVTPVSLQKGNAKQGISKAKKNRRQKSILALTACIIL
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
GIFVITNISTNNNSKTITIGSKDYTEQEILCNIFSEAIEQNTDISVKRKSALGGTQICFS
HHHHHHCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHCCCCCEEEEHHCCCHHHHHHH
ALKSGDIDMYVDYSGTCYGDTLKYTPISDVEKIYDTVKTDFKDKFNIEVLNQMGFNNTYT
HHCCCCEEEEEECCCEEECCCEECCCHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCCEEE
LAVKKETAEKYNLKTISDIAKVGDELTISPCLEFLNREDGIIGLKKTYNFNFKNEIGIDG
EEEECCCHHHCCCHHHHHHHHCCCCCCHHHHHHHHCCCCCEEEEEEEECCCCCCCCCCCC
SPKYTALMNNESDVIDAFSTDGLLKKFDLTVLEDDKNFFPPYYAIPLVRGETLEKYPEIT
CCCEEEEECCCCHHHHHHCCCCCHHHCCCEEEECCCCCCCCEEEEEEECCCHHHHCCCHH
PIIEEIAPLLTNEVMMDLNYQVDELRKDPKDVAREFLQENNLL
HHHHHHHHHHHHHHHHHCCCCHHHHCCCHHHHHHHHHHHCCCC
>Mature Secondary Structure
MMGFLNYLMEAKSQIFMLLIEHIKLTSLSVGLAIIIAMPLGICISYIKQMNKPVIAIANI
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
IQAIPSMALLGFAIPFLGIGTTPAIVMVVLYSLLPIIKNTNTGIKSINPQTLEAARGIGL
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHCCCCC
TKFQILVKVQLPLALPVIMSGVRISAVTAVGLMTMAAFIGGGGLGYLVFSGIRTVNNYQI
EEEEEEEEEECCHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCHH
LAGAIPACILALAVDFLFGIIENLVTPVSLQKGNAKQGISKAKKNRRQKSILALTACIIL
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
GIFVITNISTNNNSKTITIGSKDYTEQEILCNIFSEAIEQNTDISVKRKSALGGTQICFS
HHHHHHCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHCCCCCEEEEHHCCCHHHHHHH
ALKSGDIDMYVDYSGTCYGDTLKYTPISDVEKIYDTVKTDFKDKFNIEVLNQMGFNNTYT
HHCCCCEEEEEECCCEEECCCEECCCHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCCEEE
LAVKKETAEKYNLKTISDIAKVGDELTISPCLEFLNREDGIIGLKKTYNFNFKNEIGIDG
EEEECCCHHHCCCHHHHHHHHCCCCCCHHHHHHHHCCCCCEEEEEEEECCCCCCCCCCCC
SPKYTALMNNESDVIDAFSTDGLLKKFDLTVLEDDKNFFPPYYAIPLVRGETLEKYPEIT
CCCEEEEECCCCHHHHHHCCCCCHHHCCCEEEECCCCCCCCEEEEEEECCCHHHHCCCHH
PIIEEIAPLLTNEVMMDLNYQVDELRKDPKDVAREFLQENNLL
HHHHHHHHHHHHHHHHHCCCCHHHHCCCHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10216873; 9384377 [H]