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The map label for this gene is tadA [H]

Identifier: 187934949

GI number: 187934949

Start: 3649097

End: 3649555

Strand: Reverse

Name: tadA [H]

Synonym: CLL_A3453

Alternate gene names: 187934949

Gene position: 3649555-3649097 (Counterclockwise)

Preceding gene: 187932719

Following gene: 187934654

Centisome position: 96.03

GC content: 28.76

Gene sequence:

>459_bases
ATGAATTTTTTAGATATTGCTAAAGAAGAAGCAAGGATAGCAATGTCCAAAGGTGAAGTTCCAATTGGTGCAGTTATAGT
AAAAGATGATATTGTTATATCAAAAGCACACAATTTAAAAGAAACATTAAAAGACGCAACGGCTCATGCAGAAATATTAG
CCATAAGAAAAGCAGCTAAGTTTTTAGGGGATTGGAGATTAAAAGGTACGGAAATGTATGTTACTTTAGAACCATGTTCT
ATGTGCGCTAGTGCTATAATTCAAAGCAGAATATCAAAATTACATATAGGAACATTTAATAAGGACATGGGAGCTTGTGG
TTCTGTAATAAATCTTATAGATGATAGGCAGTTAGAATCATTTCTTAATGTTAATTGGTTATATGATGAAGAATGTTCTA
ATTTACTTATGAAATTCTTTAGTTTAAAAAGAAAAATTAATAAAAATAAATTATTATAG

Upstream 100 bases:

>100_bases
AAAAATAGAATTAAAAAAGTTAGAATATTTACAGATAACGAATAATCATAAAAGACTGCTGGCAAAAATAATCAGCAGTC
TTTTTTATGGAGGTGAAAAT

Downstream 100 bases:

>100_bases
TATATGTTATAATAAAAATTACTCACAACATATATTAAAAATAGTAGTAAAAAATTTTATAAAATTGGAGGAAAGTAATG
CAGTTTATTCAGATGCTTGA

Product: tRNA-specific adenosine deaminase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 152; Mature: 152

Protein sequence:

>152_residues
MNFLDIAKEEARIAMSKGEVPIGAVIVKDDIVISKAHNLKETLKDATAHAEILAIRKAAKFLGDWRLKGTEMYVTLEPCS
MCASAIIQSRISKLHIGTFNKDMGACGSVINLIDDRQLESFLNVNWLYDEECSNLLMKFFSLKRKINKNKLL

Sequences:

>Translated_152_residues
MNFLDIAKEEARIAMSKGEVPIGAVIVKDDIVISKAHNLKETLKDATAHAEILAIRKAAKFLGDWRLKGTEMYVTLEPCS
MCASAIIQSRISKLHIGTFNKDMGACGSVINLIDDRQLESFLNVNWLYDEECSNLLMKFFSLKRKINKNKLL
>Mature_152_residues
MNFLDIAKEEARIAMSKGEVPIGAVIVKDDIVISKAHNLKETLKDATAHAEILAIRKAAKFLGDWRLKGTEMYVTLEPCS
MCASAIIQSRISKLHIGTFNKDMGACGSVINLIDDRQLESFLNVNWLYDEECSNLLMKFFSLKRKINKNKLL

Specific function: Deaminates adenosine-34 to inosine in tRNA-Arg2 [H]

COG id: COG0590

COG function: function code FJ; Cytosine/adenosine deaminases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

Organism=Homo sapiens, GI124107608, Length=117, Percent_Identity=35.042735042735, Blast_Score=72, Evalue=3e-13,
Organism=Escherichia coli, GI145693172, Length=136, Percent_Identity=36.7647058823529, Blast_Score=100, Evalue=6e-23,
Organism=Caenorhabditis elegans, GI17554608, Length=123, Percent_Identity=39.0243902439024, Blast_Score=92, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17541138, Length=160, Percent_Identity=33.125, Blast_Score=72, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17555996, Length=103, Percent_Identity=33.9805825242718, Blast_Score=66, Evalue=8e-12,
Organism=Saccharomyces cerevisiae, GI6325319, Length=96, Percent_Identity=37.5, Blast_Score=69, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: NA

Molecular weight: Translated: 17089; Mature: 17089

Theoretical pI: Translated: 8.64; Mature: 8.64

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
6.6 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
6.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNFLDIAKEEARIAMSKGEVPIGAVIVKDDIVISKAHNLKETLKDATAHAEILAIRKAAK
CCHHHHHHHHHHHHHCCCCCCEEEEEEECCEEEECHHHHHHHHHHHHHHHHHHHHHHHHH
FLGDWRLKGTEMYVTLEPCSMCASAIIQSRISKLHIGTFNKDMGACGSVINLIDDRQLES
HHHCCEECCCEEEEEECHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHH
FLNVNWLYDEECSNLLMKFFSLKRKINKNKLL
HHCCCCEEHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MNFLDIAKEEARIAMSKGEVPIGAVIVKDDIVISKAHNLKETLKDATAHAEILAIRKAAK
CCHHHHHHHHHHHHHCCCCCCEEEEEEECCEEEECHHHHHHHHHHHHHHHHHHHHHHHHH
FLGDWRLKGTEMYVTLEPCSMCASAIIQSRISKLHIGTFNKDMGACGSVINLIDDRQLES
HHHCCEECCCEEEEEECHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHH
FLNVNWLYDEECSNLLMKFFSLKRKINKNKLL
HHCCCCEEHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1698458; 7584024; 9384377 [H]