Click here to switch to the map view.

The map label for this gene is aroK [H]

Identifier: 187934749

GI number: 187934749

Start: 3247812

End: 3248309

Strand: Reverse

Name: aroK [H]

Synonym: CLL_A3138

Alternate gene names: 187934749

Gene position: 3248309-3247812 (Counterclockwise)

Preceding gene: 187932786

Following gene: 187935030

Centisome position: 85.47

GC content: 24.9

Gene sequence:

>498_bases
ATGAAAAATAAGATATTTTTAATAGGAATGCCTGGATGTGGAAAATCTACAATTGGAGAAATTATAGCCAAAGAATTAAT
GTTAAAGTTTATAGATATGGATATATGTATTGAAGAGAAAACATCAAAAACAATTTCAGAGCTTTTTGAACAAGGTGAAG
ATTATTTTAGAGATATAGAAAGTGAAACTTGTAAGGAAATAATAAAATATGATAATGTTGTAATAGCAACTGGTGGTGGA
GTAGTAAAAAAAGATATAAATATAGAAACTTTAAAGAACAATGGATTAGTGATTTTTATTGATAGGCCAGTTGAAAAAAT
TATTTCTGATATAGATGTTTCTAGAAGGCCTCTTTTAAAAAATGGAAAAGAGAGAATTATAGGATTATATAAAGAAAGAT
ATGATATTTATAAGAAAGCATGTCATAAGATAGTTGTTAATGGTAGTACTATAGATGAAGTTGTAGGAGAAATAAAAAAA
ATAATTATTAATAACTAG

Upstream 100 bases:

>100_bases
AAGTCATCAGAAATTTGGCATGATATATCTATAAATTCTGATATACAAGAGAAAATATATTCATATATAGATGAAGAATT
TAGATAGAGGAGATTATATT

Downstream 100 bases:

>100_bases
AATTTAATGTTTATATTTTATGAAGGATAGTAGCATAGTAGAATTAAAAAAAAATTATTTGAAGTACAGGAGGAGTTTTA
AAATGATTATTATTATGAAA

Product: shikimate kinase

Products: NA

Alternate protein names: SK [H]

Number of amino acids: Translated: 165; Mature: 165

Protein sequence:

>165_residues
MKNKIFLIGMPGCGKSTIGEIIAKELMLKFIDMDICIEEKTSKTISELFEQGEDYFRDIESETCKEIIKYDNVVIATGGG
VVKKDINIETLKNNGLVIFIDRPVEKIISDIDVSRRPLLKNGKERIIGLYKERYDIYKKACHKIVVNGSTIDEVVGEIKK
IIINN

Sequences:

>Translated_165_residues
MKNKIFLIGMPGCGKSTIGEIIAKELMLKFIDMDICIEEKTSKTISELFEQGEDYFRDIESETCKEIIKYDNVVIATGGG
VVKKDINIETLKNNGLVIFIDRPVEKIISDIDVSRRPLLKNGKERIIGLYKERYDIYKKACHKIVVNGSTIDEVVGEIKK
IIINN
>Mature_165_residues
MKNKIFLIGMPGCGKSTIGEIIAKELMLKFIDMDICIEEKTSKTISELFEQGEDYFRDIESETCKEIIKYDNVVIATGGG
VVKKDINIETLKNNGLVIFIDRPVEKIISDIDVSRRPLLKNGKERIIGLYKERYDIYKKACHKIVVNGSTIDEVVGEIKK
IIINN

Specific function: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate [H]

COG id: COG0703

COG function: function code E; Shikimate kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the shikimate kinase family [H]

Homologues:

Organism=Escherichia coli, GI1786587, Length=169, Percent_Identity=30.1775147928994, Blast_Score=90, Evalue=6e-20,
Organism=Escherichia coli, GI87082255, Length=143, Percent_Identity=34.965034965035, Blast_Score=84, Evalue=4e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000623 [H]

Pfam domain/function: PF01202 SKI [H]

EC number: =2.7.1.71 [H]

Molecular weight: Translated: 18714; Mature: 18714

Theoretical pI: Translated: 7.13; Mature: 7.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNKIFLIGMPGCGKSTIGEIIAKELMLKFIDMDICIEEKTSKTISELFEQGEDYFRDIE
CCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHEECHHHHHHHHHHHHCCHHHHHHHH
SETCKEIIKYDNVVIATGGGVVKKDINIETLKNNGLVIFIDRPVEKIISDIDVSRRPLLK
HHHHHHHHHHCCEEEEECCCEEEECCCEEEECCCCEEEEECCCHHHHHHHCCCCCCCHHH
NGKERIIGLYKERYDIYKKACHKIVVNGSTIDEVVGEIKKIIINN
CCHHHHHHHHHHHHHHHHHHHHHEEECCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKNKIFLIGMPGCGKSTIGEIIAKELMLKFIDMDICIEEKTSKTISELFEQGEDYFRDIE
CCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHEECHHHHHHHHHHHHCCHHHHHHHH
SETCKEIIKYDNVVIATGGGVVKKDINIETLKNNGLVIFIDRPVEKIISDIDVSRRPLLK
HHHHHHHHHHCCEEEEECCCEEEECCCEEEECCCCEEEEECCCHHHHHHHCCCCCCCHHH
NGKERIIGLYKERYDIYKKACHKIVVNGSTIDEVVGEIKKIIINN
CCHHHHHHHHHHHHHHHHHHHHHEEECCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA