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The map label for this gene is blaR1 [H]

Identifier: 187934726

GI number: 187934726

Start: 2045979

End: 2048219

Strand: Reverse

Name: blaR1 [H]

Synonym: CLL_A1970

Alternate gene names: 187934726

Gene position: 2048219-2045979 (Counterclockwise)

Preceding gene: 187934349

Following gene: 187932701

Centisome position: 53.9

GC content: 23.92

Gene sequence:

>2241_bases
ATGGGGAGTTTAGAAAAGGTTTTTTTATGGTTTTTTCAAACATCTTTAACAGCAGCTATCATTATTTTAATAATAATTCT
GATTTTAAAAATGTTTAATAATCATATTAGTGTGCGGATTAAACATGGATTGTGGATTTTAGTAATGTTAAGACTTGTTG
TGCCTGTAATTCCAGAGGTAAATATAAATTTATTTGATATTTTTAGTGATAAATATACAAATAGTTTACAAGAAATGATA
TTAGATACATCAGGTAAAAATAGAGGAATTTCCATAGGATATAACAATTACAATAATGATACAAATAAGATGGAAAAAGT
TAATGATTATGAAAAAAATAAAGAAGAATCTATAAATAAACAAATATGGATTTCTAATTTTATAAAGATAGCTTCTTTAA
TTTGGATTATAGGGATAATCGTTTTAAGCTTAACATTCATATTATCTTTAATTAGATTTAAAAGAAAAATTATACCTTTA
GAAATATATGAAGATTTTAAAATTAAATCTATAATCAACAATTTAAAAGATAAGTTAAATATAAATTCAAAAATTCAAAT
TTTTATATATGATGGAATAAAAAGTCCTGGAATATTTGGAATTTTAAAGCCTAAAATTTATATACCACAATATGTTTTGA
AAATGGAAGATTATAATAAACTATCCTATAGTCTATTACATGAGCTTATGCACTATAAAAGAAAAGACTTATATTATAAC
TTTCTTAGTATAGTAGCTCTGTGTATACATTGGTTTAATCCTTTAGTATGGATTGCTATAAATAAAATGAAGTTGTATAG
AGAATATGCTTGTGATGCATGTGTTTTAGAATGCCTTGAAGAAAAAGAAAGAATAGATTATGGTATGACGCTTATAGAAT
TTTCAAGAATGCTTTTTTATAAAAAAGAGCAATCTAGACTGCTAATTTGTTTTGAAAATAATAACCAAATAAAAAGGAGA
ATTAAAATGATAAAAGACTTTAAAACAGGTTCATATAAAATATCAACAGTTGCTATATTAAGTTGTTTAGTAGCTACAAT
AGCAATATTTACAAATAGTATTCAAGTAAAAGGATTTGATAATGATAATGTTTCAGAAATAACATCTAATAAAGAAGAAA
ATTCTAATAATAAAGAAGAAAATTCTAAATTTTTGATTGATGCACCTTTAAAAGCTTATGATGATATTAAAAAAGCACAA
GAAATAGCAGGATTTAAATTCAAAGTGCCAGATTATATTTTAGATGGAAATGAAGTTGGAGCTGGATTTCAAGTAATAAA
AGTGTCGGATAAAGAAAATGCAGTACAAATGTTTTTTTATAATAACAATGAAAGAAACAATGGATTTTCATTAATCACAG
GAGTATCAGATCCAATAGAAATAATAAAAAAATCAGCAAGTGCACATCATGCACTAGAAGAAGATTTTAAAGTAGAAAGT
GAAAGAAATTTAGTGGATTTTAATGGAATTCATGGAGAAGAGGTTACTGTTACAATTACTTCTCCAGAAAGAAGAATAGA
AGATATTGATATTGTGATCAAAGAAATGAAGGAAATAAATAAATATTTTGTGTGGAAAGATTCAGGTATATGGTATATCT
TAGATTATAATAGACAACGTAAAGATCAAGATGAAATTAATCAATGGACAAGTATTGACAAAGAGAATATATTTAAAATA
GCAAAATCTTTGAAGTATTCAGAGGATATAAAAAACGTAAATTACTCTCCAATAAGAGAAGTTTCAACAGAAATAGGAGT
AATGAGTATATATGATAAAGGAGATTTAGAGAAAGCTAAAAAATTTCTTGGATTTAATCCTAAATTTCCATTAAAAGTAG
ATGAAGATATAAAAATAACTGGGTCAGGAGTTGGGATAACAGGAGATTCTGATATAGAAAACAATATTATAAATTACGAA
ATAAATAATTTTTATTCTGGTAAGAATTTGAGAATGACTTTTACAGCTAAAAAGGATTTAAAGTTTTACAATAATATAAA
GAAAAATGGATATTTTATTAATGAAAATACAGAGGATAATGTACCTAAAAAGATTAATGTACAAAAATTAAATATTAATA
ATAACGAGGTATTTAAATACGAAGAAAGCAATGAGTATAATTATTGTTTAGTATATATTTGGAAAGAAAATGATGTTTGT
TATTCGATTGCTTTATTTAATGAAATTGATAATCCAGATAAAATAGCTGAAGAATTTGTTAATTCTAAACCTATAGATTA
A

Upstream 100 bases:

>100_bases
TATTGATGAAATTGAAGAATTAGAAAAAATTCTTAAAGAAAAAAAGGAAAAAATCAATATAAAAGATTTTTAACTATATA
ACGAGAAGGGGTATATTTTT

Downstream 100 bases:

>100_bases
TTATTATACAATTATATAGTAACACTTTGTAAATTTATATAAATATATATTATAAAATTAAGTTCTTGTAAACATATAAG
ATGATGATAAGTATAATATT

Product: beta-lactamase regulatory protein 1

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 746; Mature: 745

Protein sequence:

>746_residues
MGSLEKVFLWFFQTSLTAAIIILIIILILKMFNNHISVRIKHGLWILVMLRLVVPVIPEVNINLFDIFSDKYTNSLQEMI
LDTSGKNRGISIGYNNYNNDTNKMEKVNDYEKNKEESINKQIWISNFIKIASLIWIIGIIVLSLTFILSLIRFKRKIIPL
EIYEDFKIKSIINNLKDKLNINSKIQIFIYDGIKSPGIFGILKPKIYIPQYVLKMEDYNKLSYSLLHELMHYKRKDLYYN
FLSIVALCIHWFNPLVWIAINKMKLYREYACDACVLECLEEKERIDYGMTLIEFSRMLFYKKEQSRLLICFENNNQIKRR
IKMIKDFKTGSYKISTVAILSCLVATIAIFTNSIQVKGFDNDNVSEITSNKEENSNNKEENSKFLIDAPLKAYDDIKKAQ
EIAGFKFKVPDYILDGNEVGAGFQVIKVSDKENAVQMFFYNNNERNNGFSLITGVSDPIEIIKKSASAHHALEEDFKVES
ERNLVDFNGIHGEEVTVTITSPERRIEDIDIVIKEMKEINKYFVWKDSGIWYILDYNRQRKDQDEINQWTSIDKENIFKI
AKSLKYSEDIKNVNYSPIREVSTEIGVMSIYDKGDLEKAKKFLGFNPKFPLKVDEDIKITGSGVGITGDSDIENNIINYE
INNFYSGKNLRMTFTAKKDLKFYNNIKKNGYFINENTEDNVPKKINVQKLNINNNEVFKYEESNEYNYCLVYIWKENDVC
YSIALFNEIDNPDKIAEEFVNSKPID

Sequences:

>Translated_746_residues
MGSLEKVFLWFFQTSLTAAIIILIIILILKMFNNHISVRIKHGLWILVMLRLVVPVIPEVNINLFDIFSDKYTNSLQEMI
LDTSGKNRGISIGYNNYNNDTNKMEKVNDYEKNKEESINKQIWISNFIKIASLIWIIGIIVLSLTFILSLIRFKRKIIPL
EIYEDFKIKSIINNLKDKLNINSKIQIFIYDGIKSPGIFGILKPKIYIPQYVLKMEDYNKLSYSLLHELMHYKRKDLYYN
FLSIVALCIHWFNPLVWIAINKMKLYREYACDACVLECLEEKERIDYGMTLIEFSRMLFYKKEQSRLLICFENNNQIKRR
IKMIKDFKTGSYKISTVAILSCLVATIAIFTNSIQVKGFDNDNVSEITSNKEENSNNKEENSKFLIDAPLKAYDDIKKAQ
EIAGFKFKVPDYILDGNEVGAGFQVIKVSDKENAVQMFFYNNNERNNGFSLITGVSDPIEIIKKSASAHHALEEDFKVES
ERNLVDFNGIHGEEVTVTITSPERRIEDIDIVIKEMKEINKYFVWKDSGIWYILDYNRQRKDQDEINQWTSIDKENIFKI
AKSLKYSEDIKNVNYSPIREVSTEIGVMSIYDKGDLEKAKKFLGFNPKFPLKVDEDIKITGSGVGITGDSDIENNIINYE
INNFYSGKNLRMTFTAKKDLKFYNNIKKNGYFINENTEDNVPKKINVQKLNINNNEVFKYEESNEYNYCLVYIWKENDVC
YSIALFNEIDNPDKIAEEFVNSKPID
>Mature_745_residues
GSLEKVFLWFFQTSLTAAIIILIIILILKMFNNHISVRIKHGLWILVMLRLVVPVIPEVNINLFDIFSDKYTNSLQEMIL
DTSGKNRGISIGYNNYNNDTNKMEKVNDYEKNKEESINKQIWISNFIKIASLIWIIGIIVLSLTFILSLIRFKRKIIPLE
IYEDFKIKSIINNLKDKLNINSKIQIFIYDGIKSPGIFGILKPKIYIPQYVLKMEDYNKLSYSLLHELMHYKRKDLYYNF
LSIVALCIHWFNPLVWIAINKMKLYREYACDACVLECLEEKERIDYGMTLIEFSRMLFYKKEQSRLLICFENNNQIKRRI
KMIKDFKTGSYKISTVAILSCLVATIAIFTNSIQVKGFDNDNVSEITSNKEENSNNKEENSKFLIDAPLKAYDDIKKAQE
IAGFKFKVPDYILDGNEVGAGFQVIKVSDKENAVQMFFYNNNERNNGFSLITGVSDPIEIIKKSASAHHALEEDFKVESE
RNLVDFNGIHGEEVTVTITSPERRIEDIDIVIKEMKEINKYFVWKDSGIWYILDYNRQRKDQDEINQWTSIDKENIFKIA
KSLKYSEDIKNVNYSPIREVSTEIGVMSIYDKGDLEKAKKFLGFNPKFPLKVDEDIKITGSGVGITGDSDIENNIINYEI
NNFYSGKNLRMTFTAKKDLKFYNNIKKNGYFINENTEDNVPKKINVQKLNINNNEVFKYEESNEYNYCLVYIWKENDVCY
SIALFNEIDNPDKIAEEFVNSKPID

Specific function: BlaR1 is a potential penicillin-binding protein required for induction of beta-lactamase in Bacillus licheniformis [H]

COG id: COG4219

COG function: function code KT; Antirepressor regulating drug resistance, predicted signal transduction N-terminal membrane component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M56 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR001460
- InterPro:   IPR008756 [H]

Pfam domain/function: PF05569 Peptidase_M56; PF00905 Transpeptidase [H]

EC number: NA

Molecular weight: Translated: 87038; Mature: 86907

Theoretical pI: Translated: 6.73; Mature: 6.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGSLEKVFLWFFQTSLTAAIIILIIILILKMFNNHISVRIKHGLWILVMLRLVVPVIPEV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHCCCCC
NINLFDIFSDKYTNSLQEMILDTSGKNRGISIGYNNYNNDTNKMEKVNDYEKNKEESINK
CCEEEEEHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCHHHHHHHHHHHCCHHHHCCH
QIWISNFIKIASLIWIIGIIVLSLTFILSLIRFKRKIIPLEIYEDFKIKSIINNLKDKLN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEHHCCCHHHHHHHHHHHHCC
INSKIQIFIYDGIKSPGIFGILKPKIYIPQYVLKMEDYNKLSYSLLHELMHYKRKDLYYN
CCCEEEEEEEECCCCCCEEEEECCCEECCHHHEECCCCCHHHHHHHHHHHHHHHHHHHHH
FLSIVALCIHWFNPLVWIAINKMKLYREYACDACVLECLEEKERIDYGMTLIEFSRMLFY
HHHHHHHHHHHHCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHE
KKEQSRLLICFENNNQIKRRIKMIKDFKTGSYKISTVAILSCLVATIAIFTNSIQVKGFD
EECCCEEEEEEECCCHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHCCEEEEECC
NDNVSEITSNKEENSNNKEENSKFLIDAPLKAYDDIKKAQEIAGFKFKVPDYILDGNEVG
CCCHHHHHCCCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHCCCEEECCCEEECCCCCC
AGFQVIKVSDKENAVQMFFYNNNERNNGFSLITGVSDPIEIIKKSASAHHALEEDFKVES
CCEEEEEECCCCCEEEEEEEECCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCC
ERNLVDFNGIHGEEVTVTITSPERRIEDIDIVIKEMKEINKYFVWKDSGIWYILDYNRQR
CCCEEEECCCCCCEEEEEEECCHHHHHHHHHHHHHHHHCCCEEEEECCCEEEEEECCCCC
KDQDEINQWTSIDKENIFKIAKSLKYSEDIKNVNYSPIREVSTEIGVMSIYDKGDLEKAK
CCHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCEEEEECCCCHHHHH
KFLGFNPKFPLKVDEDIKITGSGVGITGDSDIENNIINYEINNFYSGKNLRMTFTAKKDL
HHHCCCCCCCCEECCCCEEECCCEECCCCCCCCCCEEEEEECCEECCCCEEEEEEEHHHH
KFYNNIKKNGYFINENTEDNVPKKINVQKLNINNNEVFKYEESNEYNYCLVYIWKENDVC
HHHHCCCCCCEEECCCCCCCCCCEEEEEEEECCCCEEEEEECCCCCCEEEEEEECCCCEE
YSIALFNEIDNPDKIAEEFVNSKPID
EEEEEECCCCCHHHHHHHHHCCCCCC
>Mature Secondary Structure 
GSLEKVFLWFFQTSLTAAIIILIIILILKMFNNHISVRIKHGLWILVMLRLVVPVIPEV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHCCCCC
NINLFDIFSDKYTNSLQEMILDTSGKNRGISIGYNNYNNDTNKMEKVNDYEKNKEESINK
CCEEEEEHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCHHHHHHHHHHHCCHHHHCCH
QIWISNFIKIASLIWIIGIIVLSLTFILSLIRFKRKIIPLEIYEDFKIKSIINNLKDKLN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEHHCCCHHHHHHHHHHHHCC
INSKIQIFIYDGIKSPGIFGILKPKIYIPQYVLKMEDYNKLSYSLLHELMHYKRKDLYYN
CCCEEEEEEEECCCCCCEEEEECCCEECCHHHEECCCCCHHHHHHHHHHHHHHHHHHHHH
FLSIVALCIHWFNPLVWIAINKMKLYREYACDACVLECLEEKERIDYGMTLIEFSRMLFY
HHHHHHHHHHHHCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHE
KKEQSRLLICFENNNQIKRRIKMIKDFKTGSYKISTVAILSCLVATIAIFTNSIQVKGFD
EECCCEEEEEEECCCHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHCCEEEEECC
NDNVSEITSNKEENSNNKEENSKFLIDAPLKAYDDIKKAQEIAGFKFKVPDYILDGNEVG
CCCHHHHHCCCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHCCCEEECCCEEECCCCCC
AGFQVIKVSDKENAVQMFFYNNNERNNGFSLITGVSDPIEIIKKSASAHHALEEDFKVES
CCEEEEEECCCCCEEEEEEEECCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCC
ERNLVDFNGIHGEEVTVTITSPERRIEDIDIVIKEMKEINKYFVWKDSGIWYILDYNRQR
CCCEEEECCCCCCEEEEEEECCHHHHHHHHHHHHHHHHCCCEEEEECCCEEEEEECCCCC
KDQDEINQWTSIDKENIFKIAKSLKYSEDIKNVNYSPIREVSTEIGVMSIYDKGDLEKAK
CCHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCEEEEECCCCHHHHH
KFLGFNPKFPLKVDEDIKITGSGVGITGDSDIENNIINYEINNFYSGKNLRMTFTAKKDL
HHHCCCCCCCCEECCCCEEECCCEECCCCCCCCCCEEEEEECCEECCCCEEEEEEEHHHH
KFYNNIKKNGYFINENTEDNVPKKINVQKLNINNNEVFKYEESNEYNYCLVYIWKENDVC
HHHHCCCCCCEEECCCCCCCCCCEEEEEEEECCCCEEEEEECCCCCCEEEEEEECCCCEE
YSIALFNEIDNPDKIAEEFVNSKPID
EEEEEECCCCCHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3040663; 3260234; 2404938 [H]