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The map label for this gene is ntpI [H]

Identifier: 187934721

GI number: 187934721

Start: 2941689

End: 2943623

Strand: Reverse

Name: ntpI [H]

Synonym: CLL_A2866

Alternate gene names: 187934721

Gene position: 2943623-2941689 (Counterclockwise)

Preceding gene: 187932952

Following gene: 187935387

Centisome position: 77.46

GC content: 29.82

Gene sequence:

>1935_bases
TTGTTAGCCTTTGAATCAAAGAAAAATGAACTTCTTGAAAGAATACAAAATTTCTCAGAAGTTGAATTTATTAATCTACA
AGATGAGAACATTCAAGAAAAAAATGAAGTTCTTAATGAGTTAGATAAAGATCAAATTGATTCTGACATATCAAGGTGGG
AAGAAGAATTATCAAAAGCTAAATTTGCCCTACAGTTCTTAAAGGACTATGTGCCTAAACAATCATTAATAAAGTCTTTA
CGTACAGAAAAGCTTTCATTAACTCCTAAAGAACTAGAACAAAGAGTAATAAATGGAGAATGGGAAAGTGTATATGATAG
AGTTAAAGAAAAAGAACATGCTTTAGCTTCATTAGACAATGAAAAGACTAGATTACAAGGAAATGTTCAAAGCTTAAAAT
CATATGAAAATTTTAATGCACCATTAGGGTGTTTAGATGATTTAAAAGTAACTGAATATTTCTTGGGAAGCATTGCTAAC
CAATATGAGGAAGCATTGAAAAATGATTTAAATGATTGTTATTTAGAAATTATATCAAAAGACAATCAAGACACTTACTT
CTTCCTTTTAGATCATAAGGATAATAAAGAAGAAGTGGAAGAGGTGCTAAGAGGGTTTGGATTTAGTCCGTTTAAAACAG
ATGAGAAAGAACTCCCTTTAAAGCTTATTCAAGAATATAACGAAAGAATATCCTTAATCGATTCTGAAAAATTCTTAGTA
AAAGAAGAATTATCAGGATTTGAGGAAAGTTTAGAAAGCTTGAAATTAGCTTATGAATATTATTATAACTTAGTAAATAG
AAAATCTATTACTAATAGATTTTTAAAGACGGATAAAACTGTCTTATTACAAGGTTGGGTTCCTAGCGAAAAAAATGATA
GGTTAACTCAAATTACTAAGGATGTATTAGGTGAAGATTACTATTTAGCTTTTGAAGATGTTAAAGAAGAAGAAATTGAT
GATGTACCTATTAAATTAGAAAATAATGATTTAAATGCATCATTTGAATCAGTAACATCAATGTATGCTTTACCTAAGTA
TAATGACATAGACCCAACACCATTAGTTGCGCCATTCTATTTAGCTTTCTTTGGAATGATGGTTGCAGATGCAGGTTATG
GGTTATTAATGTTGTTAGGAACAATTGGAGCATTAAAATTATTTAATTTTGATGCAGAAAAGAAAAAGATGGTTAAGTTC
TTTATGTATTTAAGTTTCCCAACAATTGTATTTGGATTAATTTACGGTTCATTCTTTGGAGACTTAATAGGCATTAAAGG
TTTAATTGATACAAATCGAGATGTTATGACGATACTAACTATGTCAGTAGTATTTGGTGCAATTCAGATTGTATTTGGAT
TATTAATAAAAGCAGCGGTATTAATAAGAGCAGGAAAAACATTAGATGCTTTTATGGATGCAGGATCATGGCTTATAACT
CTATTTTCTATTGGAGGAATTGCAGCTGGATCAATGCTTAATATACCAACACTTAAGACAGTATCTATAGCAGGAGCTAT
TATTGGTTCTATATTAATTGTTTTAACACAAGGAAGACAAATGGAATCAAAAGGTGGAAAAATAGGTCAAGGTCTTTATG
AACTATATGGTATTACAGGATACGTAAGTGACTTAGTATCATACACAAGACTTATGGCGATAGGTTTATCAGGTGGATCT
ATAGCAGGAGCTATAAACATGATTATGAGAATGGTATCAGATGATGGTAATTCCCTTTTAGGAACTATTCTTTTTGCACC
ATTAATATTTATCATGTTCCAAACAGTAAACTTATTACTATCATTATTAAGCGGTTATGTTCATACATTAAGACTTACTT
ATGTTGAATATTTCTCAAAATTTTACGACGGTGGCGGAAAAGCATTTAAGCCACTTGAAGCAAAAAATGAATACATTAAT
TTAAGAGAAGAGTAG

Upstream 100 bases:

>100_bases
ATATTACATATATCTGAAGATAAGAAAAATAATGCTGTTAAATTAGTGATTGAGAGGATAGTGAAGATTCATGGCAATAG
TTAAGATGAATAAGTTCACC

Downstream 100 bases:

>100_bases
GAGGACATTTAAAATGGATATGAGTTGGATTAAGTTTTTTTTAGAAAATAACGGTGGATTTGTTATGGGAGCACTAGGTG
TTGCTTTAGCAGTAGGAATG

Product: V-type ATP synthase subunit I

Products: ADP; phosphate; H+

Alternate protein names: Na(+)-translocating ATPase subunit I; V-type sodium pump subunit I [H]

Number of amino acids: Translated: 644; Mature: 644

Protein sequence:

>644_residues
MLAFESKKNELLERIQNFSEVEFINLQDENIQEKNEVLNELDKDQIDSDISRWEEELSKAKFALQFLKDYVPKQSLIKSL
RTEKLSLTPKELEQRVINGEWESVYDRVKEKEHALASLDNEKTRLQGNVQSLKSYENFNAPLGCLDDLKVTEYFLGSIAN
QYEEALKNDLNDCYLEIISKDNQDTYFFLLDHKDNKEEVEEVLRGFGFSPFKTDEKELPLKLIQEYNERISLIDSEKFLV
KEELSGFEESLESLKLAYEYYYNLVNRKSITNRFLKTDKTVLLQGWVPSEKNDRLTQITKDVLGEDYYLAFEDVKEEEID
DVPIKLENNDLNASFESVTSMYALPKYNDIDPTPLVAPFYLAFFGMMVADAGYGLLMLLGTIGALKLFNFDAEKKKMVKF
FMYLSFPTIVFGLIYGSFFGDLIGIKGLIDTNRDVMTILTMSVVFGAIQIVFGLLIKAAVLIRAGKTLDAFMDAGSWLIT
LFSIGGIAAGSMLNIPTLKTVSIAGAIIGSILIVLTQGRQMESKGGKIGQGLYELYGITGYVSDLVSYTRLMAIGLSGGS
IAGAINMIMRMVSDDGNSLLGTILFAPLIFIMFQTVNLLLSLLSGYVHTLRLTYVEYFSKFYDGGGKAFKPLEAKNEYIN
LREE

Sequences:

>Translated_644_residues
MLAFESKKNELLERIQNFSEVEFINLQDENIQEKNEVLNELDKDQIDSDISRWEEELSKAKFALQFLKDYVPKQSLIKSL
RTEKLSLTPKELEQRVINGEWESVYDRVKEKEHALASLDNEKTRLQGNVQSLKSYENFNAPLGCLDDLKVTEYFLGSIAN
QYEEALKNDLNDCYLEIISKDNQDTYFFLLDHKDNKEEVEEVLRGFGFSPFKTDEKELPLKLIQEYNERISLIDSEKFLV
KEELSGFEESLESLKLAYEYYYNLVNRKSITNRFLKTDKTVLLQGWVPSEKNDRLTQITKDVLGEDYYLAFEDVKEEEID
DVPIKLENNDLNASFESVTSMYALPKYNDIDPTPLVAPFYLAFFGMMVADAGYGLLMLLGTIGALKLFNFDAEKKKMVKF
FMYLSFPTIVFGLIYGSFFGDLIGIKGLIDTNRDVMTILTMSVVFGAIQIVFGLLIKAAVLIRAGKTLDAFMDAGSWLIT
LFSIGGIAAGSMLNIPTLKTVSIAGAIIGSILIVLTQGRQMESKGGKIGQGLYELYGITGYVSDLVSYTRLMAIGLSGGS
IAGAINMIMRMVSDDGNSLLGTILFAPLIFIMFQTVNLLLSLLSGYVHTLRLTYVEYFSKFYDGGGKAFKPLEAKNEYIN
LREE
>Mature_644_residues
MLAFESKKNELLERIQNFSEVEFINLQDENIQEKNEVLNELDKDQIDSDISRWEEELSKAKFALQFLKDYVPKQSLIKSL
RTEKLSLTPKELEQRVINGEWESVYDRVKEKEHALASLDNEKTRLQGNVQSLKSYENFNAPLGCLDDLKVTEYFLGSIAN
QYEEALKNDLNDCYLEIISKDNQDTYFFLLDHKDNKEEVEEVLRGFGFSPFKTDEKELPLKLIQEYNERISLIDSEKFLV
KEELSGFEESLESLKLAYEYYYNLVNRKSITNRFLKTDKTVLLQGWVPSEKNDRLTQITKDVLGEDYYLAFEDVKEEEID
DVPIKLENNDLNASFESVTSMYALPKYNDIDPTPLVAPFYLAFFGMMVADAGYGLLMLLGTIGALKLFNFDAEKKKMVKF
FMYLSFPTIVFGLIYGSFFGDLIGIKGLIDTNRDVMTILTMSVVFGAIQIVFGLLIKAAVLIRAGKTLDAFMDAGSWLIT
LFSIGGIAAGSMLNIPTLKTVSIAGAIIGSILIVLTQGRQMESKGGKIGQGLYELYGITGYVSDLVSYTRLMAIGLSGGS
IAGAINMIMRMVSDDGNSLLGTILFAPLIFIMFQTVNLLLSLLSGYVHTLRLTYVEYFSKFYDGGGKAFKPLEAKNEYIN
LREE

Specific function: Involved in ATP-driven sodium extrusion [H]

COG id: COG1269

COG function: function code C; Archaeal/vacuolar-type H+-ATPase subunit I

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the V-ATPase 116 kDa subunit family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002490 [H]

Pfam domain/function: PF01496 V_ATPase_I [H]

EC number: 3.6.3.14

Molecular weight: Translated: 72924; Mature: 72924

Theoretical pI: Translated: 4.47; Mature: 4.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLAFESKKNELLERIQNFSEVEFINLQDENIQEKNEVLNELDKDQIDSDISRWEEELSKA
CCCCCCHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHH
KFALQFLKDYVPKQSLIKSLRTEKLSLTPKELEQRVINGEWESVYDRVKEKEHALASLDN
HHHHHHHHHHCCHHHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCC
EKTRLQGNVQSLKSYENFNAPLGCLDDLKVTEYFLGSIANQYEEALKNDLNDCYLEIISK
CHHHHHCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
DNQDTYFFLLDHKDNKEEVEEVLRGFGFSPFKTDEKELPLKLIQEYNERISLIDSEKFLV
CCCCEEEEEEECCCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHH
KEELSGFEESLESLKLAYEYYYNLVNRKSITNRFLKTDKTVLLQGWVPSEKNDRLTQITK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCHHHHHHH
DVLGEDYYLAFEDVKEEEIDDVPIKLENNDLNASFESVTSMYALPKYNDIDPTPLVAPFY
HHCCCCEEEEHHHCCHHCCCCCCEEEECCCCCCHHHHHHHHHCCCCCCCCCCCCHHHHHH
LAFFGMMVADAGYGLLMLLGTIGALKLFNFDAEKKKMVKFFMYLSFPTIVFGLIYGSFFG
HHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DLIGIKGLIDTNRDVMTILTMSVVFGAIQIVFGLLIKAAVLIRAGKTLDAFMDAGSWLIT
HHHHHCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCHHHHH
LFSIGGIAAGSMLNIPTLKTVSIAGAIIGSILIVLTQGRQMESKGGKIGQGLYELYGITG
HHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHCCCCHHHHHHHHHHHHH
YVSDLVSYTRLMAIGLSGGSIAGAINMIMRMVSDDGNSLLGTILFAPLIFIMFQTVNLLL
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
SLLSGYVHTLRLTYVEYFSKFYDGGGKAFKPLEAKNEYINLREE
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MLAFESKKNELLERIQNFSEVEFINLQDENIQEKNEVLNELDKDQIDSDISRWEEELSKA
CCCCCCHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHH
KFALQFLKDYVPKQSLIKSLRTEKLSLTPKELEQRVINGEWESVYDRVKEKEHALASLDN
HHHHHHHHHHCCHHHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCC
EKTRLQGNVQSLKSYENFNAPLGCLDDLKVTEYFLGSIANQYEEALKNDLNDCYLEIISK
CHHHHHCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
DNQDTYFFLLDHKDNKEEVEEVLRGFGFSPFKTDEKELPLKLIQEYNERISLIDSEKFLV
CCCCEEEEEEECCCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHH
KEELSGFEESLESLKLAYEYYYNLVNRKSITNRFLKTDKTVLLQGWVPSEKNDRLTQITK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCHHHHHHH
DVLGEDYYLAFEDVKEEEIDDVPIKLENNDLNASFESVTSMYALPKYNDIDPTPLVAPFY
HHCCCCEEEEHHHCCHHCCCCCCEEEECCCCCCHHHHHHHHHCCCCCCCCCCCCHHHHHH
LAFFGMMVADAGYGLLMLLGTIGALKLFNFDAEKKKMVKFFMYLSFPTIVFGLIYGSFFG
HHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DLIGIKGLIDTNRDVMTILTMSVVFGAIQIVFGLLIKAAVLIRAGKTLDAFMDAGSWLIT
HHHHHCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCHHHHH
LFSIGGIAAGSMLNIPTLKTVSIAGAIIGSILIVLTQGRQMESKGGKIGQGLYELYGITG
HHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHCCCCHHHHHHHHHHHHH
YVSDLVSYTRLMAIGLSGGSIAGAINMIMRMVSDDGNSLLGTILFAPLIFIMFQTVNLLL
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
SLLSGYVHTLRLTYVEYFSKFYDGGGKAFKPLEAKNEYINLREE
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; H2O; H+

Specific reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out)

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8157629; 8144530 [H]