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The map label for this gene is dagK [H]

Identifier: 187934676

GI number: 187934676

Start: 3192980

End: 3193858

Strand: Reverse

Name: dagK [H]

Synonym: CLL_A3085

Alternate gene names: 187934676

Gene position: 3193858-3192980 (Counterclockwise)

Preceding gene: 187933150

Following gene: 187935640

Centisome position: 84.04

GC content: 27.99

Gene sequence:

>879_bases
ATGAAAAAGGTTAAATTCATATATAACCCGTACTCAGGAGAAAATATCATAGTTAATGAGATAGATAATGTTATAAAATT
ACATGAAGAAGCGGAATTGCAAATTATTCCTTATAGAATTCAAAGGGGTAAATCTTTGGAGGAAGCTTTAGAAGATATAG
ATAATACTTATAAATATATATTAATAGCTGGTGGAGATGGAACTGTTGATTCAGTTGTGAATGCCATGAAAAAAAGAAAA
ATAGATTTACCAATAGGTATATTACCAGTAGGAACTGCAAATGATTTTGGAAAATTTATTAATATACCCAATAACATTAT
AGATGCCTGCAATAAAATTTTGAAATCAAAACCTGTTGGGGTTGACCTTGGTAAGATAAATGACAAGTACTTTATAAATG
TAGCAAGTACAGGACTTTTTACTGATGTTTCTCAGAAGACCGATGTAAATTTAAAGAACACCATAGGTAAATTAGCATAT
TATTTAAAAGGTATAGAAGAGTTACCGAATTTTAGAAGATTAAAAGTAAATATAAAATCTAAAGAGTGTAATTATGATGG
TGAAATGTATCTCTTATTAGTATTCAATGGAGAAAGTGCTGGTAACTTTAGATTAGCTACAGAAGCAGATGTGACAGATG
GTAAGCTTGATGTAATTGTATTTAAAGCAATTCCAATTATTGAATTAATACCATTATTTATTAAGATATTAAAAGGAGAG
CACTTAGATTCTAACAAAGTAGTATACTTTAAAACAGATGACTTATATATTGAATGTAATGAAGAAATAGTTACAGATAT
TGATGGAGAACGAGGACCAGATTTTCCATTAAATATTAAATGTATTAAAGGTGGAATTAAAGTTTTAGGAATTGATTAG

Upstream 100 bases:

>100_bases
TACCAAAAAAATACAAAAAACATAATATATTATCGACATTAAAAGTACAAAATGATATAATCATCTGTATAACAAATTTG
GTTGGAGGGAATTTATATTT

Downstream 100 bases:

>100_bases
TTAAGTAATTATTAATTAGTTATAGGTATAAAATATGTAATTATATAATAAATATAAGTAACAGGAATGTAGATAGGAGT
GTAATTTGTGAATTTTGCAT

Product: lipid kinase

Products: NA

Alternate protein names: DAG kinase; DAGK [H]

Number of amino acids: Translated: 292; Mature: 292

Protein sequence:

>292_residues
MKKVKFIYNPYSGENIIVNEIDNVIKLHEEAELQIIPYRIQRGKSLEEALEDIDNTYKYILIAGGDGTVDSVVNAMKKRK
IDLPIGILPVGTANDFGKFINIPNNIIDACNKILKSKPVGVDLGKINDKYFINVASTGLFTDVSQKTDVNLKNTIGKLAY
YLKGIEELPNFRRLKVNIKSKECNYDGEMYLLLVFNGESAGNFRLATEADVTDGKLDVIVFKAIPIIELIPLFIKILKGE
HLDSNKVVYFKTDDLYIECNEEIVTDIDGERGPDFPLNIKCIKGGIKVLGID

Sequences:

>Translated_292_residues
MKKVKFIYNPYSGENIIVNEIDNVIKLHEEAELQIIPYRIQRGKSLEEALEDIDNTYKYILIAGGDGTVDSVVNAMKKRK
IDLPIGILPVGTANDFGKFINIPNNIIDACNKILKSKPVGVDLGKINDKYFINVASTGLFTDVSQKTDVNLKNTIGKLAY
YLKGIEELPNFRRLKVNIKSKECNYDGEMYLLLVFNGESAGNFRLATEADVTDGKLDVIVFKAIPIIELIPLFIKILKGE
HLDSNKVVYFKTDDLYIECNEEIVTDIDGERGPDFPLNIKCIKGGIKVLGID
>Mature_292_residues
MKKVKFIYNPYSGENIIVNEIDNVIKLHEEAELQIIPYRIQRGKSLEEALEDIDNTYKYILIAGGDGTVDSVVNAMKKRK
IDLPIGILPVGTANDFGKFINIPNNIIDACNKILKSKPVGVDLGKINDKYFINVASTGLFTDVSQKTDVNLKNTIGKLAY
YLKGIEELPNFRRLKVNIKSKECNYDGEMYLLLVFNGESAGNFRLATEADVTDGKLDVIVFKAIPIIELIPLFIKILKGE
HLDSNKVVYFKTDDLYIECNEEIVTDIDGERGPDFPLNIKCIKGGIKVLGID

Specific function: Catalyzes the phosphorylation of diacylglycerol (DAG) into phosphatidic acid. Is a key enzyme involved in the production of lipoteichoic acid by reintroducing DAG formed from the breakdown of membrane phospholipids into the phosphatidylglycerol biosynthet

COG id: COG1597

COG function: function code IR; Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 DAGKc domain [H]

Homologues:

Organism=Escherichia coli, GI1788402, Length=287, Percent_Identity=25.0871080139373, Blast_Score=97, Evalue=9e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017438
- InterPro:   IPR005218
- InterPro:   IPR001206 [H]

Pfam domain/function: PF00781 DAGK_cat [H]

EC number: =2.7.1.107 [H]

Molecular weight: Translated: 32694; Mature: 32694

Theoretical pI: Translated: 5.12; Mature: 5.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKVKFIYNPYSGENIIVNEIDNVIKLHEEAELQIIPYRIQRGKSLEEALEDIDNTYKYI
CCCEEEEECCCCCCEEEEEHHHHHHHHCCCCCEEEEEEEECCCCCHHHHHHHCCCCEEEE
LIAGGDGTVDSVVNAMKKRKIDLPIGILPVGTANDFGKFINIPNNIIDACNKILKSKPVG
EEECCCCCHHHHHHHHHHCCCCCCEEEEECCCCCCCHHEECCCHHHHHHHHHHHHCCCCC
VDLGKINDKYFINVASTGLFTDVSQKTDVNLKNTIGKLAYYLKGIEELPNFRRLKVNIKS
EEECCCCCEEEEEEECCCEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEEEC
KECNYDGEMYLLLVFNGESAGNFRLATEADVTDGKLDVIVFKAIPIIELIPLFIKILKGE
CCCCCCCCEEEEEEECCCCCCCEEEEECCCCCCCCEEEEEEECCCHHHHHHHHHHHHCCC
HLDSNKVVYFKTDDLYIECNEEIVTDIDGERGPDFPLNIKCIKGGIKVLGID
CCCCCCEEEEECCCEEEEECCCEEECCCCCCCCCCCEEEEEEECCEEEEEEC
>Mature Secondary Structure
MKKVKFIYNPYSGENIIVNEIDNVIKLHEEAELQIIPYRIQRGKSLEEALEDIDNTYKYI
CCCEEEEECCCCCCEEEEEHHHHHHHHCCCCCEEEEEEEECCCCCHHHHHHHCCCCEEEE
LIAGGDGTVDSVVNAMKKRKIDLPIGILPVGTANDFGKFINIPNNIIDACNKILKSKPVG
EEECCCCCHHHHHHHHHHCCCCCCEEEEECCCCCCCHHEECCCHHHHHHHHHHHHCCCCC
VDLGKINDKYFINVASTGLFTDVSQKTDVNLKNTIGKLAYYLKGIEELPNFRRLKVNIKS
EEECCCCCEEEEEEECCCEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEEEC
KECNYDGEMYLLLVFNGESAGNFRLATEADVTDGKLDVIVFKAIPIIELIPLFIKILKGE
CCCCCCCCEEEEEEECCCCCCCEEEEECCCCCCCCEEEEEEECCCHHHHHHHHHHHHCCC
HLDSNKVVYFKTDDLYIECNEEIVTDIDGERGPDFPLNIKCIKGGIKVLGID
CCCCCCEEEEECCCEEEEECCCEEECCCCCCCCCCCEEEEEEECCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA