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The map label for this gene is murA [H]

Identifier: 187934606

GI number: 187934606

Start: 3759832

End: 3761094

Strand: Reverse

Name: murA [H]

Synonym: CLL_A3552

Alternate gene names: 187934606

Gene position: 3761094-3759832 (Counterclockwise)

Preceding gene: 187933752

Following gene: 187935301

Centisome position: 98.97

GC content: 33.81

Gene sequence:

>1263_bases
ATGGAAAGATTGATAATAAATGGAGGGAATATTCTTAGAGGGTCTGTTGAGATCAATGGCGCTAAAAATGCAGCTGTAGC
AATATTGCCAGCAGCTATAATGGCTAGTGAAGGAAAATGTGTAATTGATAATATACCAGATATTGAAGATGTACATTGCC
TTGAAAGAATATTAGAAAGTTTAGGTTGTAATACAGTAAAAATAGATAATAATACATTAGAGATAGATAGTACGAATGTA
AGTAATTTTGATGCCTCAACTGAGGATGTAAGAAGAATGAGAGCATCGTATTACTTTATAGGAGCTTTATTAGCAAGATT
TAAGCAAGCAAAGGTTGTATTACCTGGTGGATGTCCAATTGGTGTTAGACCGATAGATCAACACATAAAAGGATTTGAAG
CTCTTGGTGCAGAAGTTATTATAGAACATGGTGCTGTAATAGTAAAAGCAAAAAAATTACAAGGAACAAATATATTCTTT
GATGTAGTATCAGTAGGTGCTACAATAAATGTGATGATTGCAGCAACATTAGCAGATGGTGTTACTACTCTTGAAAACGT
GGCTAAAGAACCACATGTAGTTGACGTAGCTAATTTCTTAAACTCAATGGGTGCAAATATTAAAGGTGCTGGTACTGATA
TTATTAGAATACAAGGTGTTGAAAAATTAAAAGGTTGTTCTTATAGTGTTATACCTGACCAAATAGAAGCTGGTACATTT
ATGATAGCAGCTGTTGCAACTCGTGGAGATGTTTATGTAAGGAATGTTATTCCAAAGCATTTAGAATCAATTTCAGCAAA
ACTTAAAGAAATGGGTGCAGTAATTGAAGAAGATGATGATTGTATAAGGGTTTGCGCTAGTGATGAACTAAAAGCAGTAA
ACGTAAAGACTACTCCTTATCCAGGATTCCCTACTGATATTCAACAACCTATGTCAGCTTTATTAAGCGTTATTTATGGA
AAAAGTATAGTTACTGAGTCTATATGGGAAAATAGACATAAACATATAGATGAACTTAAAAAGATGGGCGCTAACATAAA
AGTTGAAGGTAGAGTAGCTATTATTGAAGGAGTTAAAAGACTTACTGGAGCAGTAGTGAAAGCAACTGATTTAAGAGCTG
GAGCTGCTATGGTTATAGCTGGTTTATTAGCTGAAGGAAGAACAGAAATAACAAGTATAGAACATATAGATAGAGGATAT
CCACATATAGAAAATAAATTAAGAGCTTTAGGGGCGGATATAAAGAGGACTACAGTAGAATAG

Upstream 100 bases:

>100_bases
TTTTAATAAATATAATAGGACAATAATGTCTAATTAAAATATAGATATAATCAGGAGTTTAACGTATTTAAATATAGATT
TTATGAATAGGGTGAATTCG

Downstream 100 bases:

>100_bases
AGTGGCTTTTTATGTTATCATAGGAGGAATTTAAATGATATTCTGTTCTTTATACAGTGGAAGCAGTGGTAATAGTATGT
TTGTTGCTTCTGAAAAATCA

Product: UDP-N-acetylglucosamine 1-carboxyvinyltransferase

Products: NA

Alternate protein names: Enoylpyruvate transferase 2; UDP-N-acetylglucosamine enolpyruvyl transferase 2; EPT 2 [H]

Number of amino acids: Translated: 420; Mature: 420

Protein sequence:

>420_residues
MERLIINGGNILRGSVEINGAKNAAVAILPAAIMASEGKCVIDNIPDIEDVHCLERILESLGCNTVKIDNNTLEIDSTNV
SNFDASTEDVRRMRASYYFIGALLARFKQAKVVLPGGCPIGVRPIDQHIKGFEALGAEVIIEHGAVIVKAKKLQGTNIFF
DVVSVGATINVMIAATLADGVTTLENVAKEPHVVDVANFLNSMGANIKGAGTDIIRIQGVEKLKGCSYSVIPDQIEAGTF
MIAAVATRGDVYVRNVIPKHLESISAKLKEMGAVIEEDDDCIRVCASDELKAVNVKTTPYPGFPTDIQQPMSALLSVIYG
KSIVTESIWENRHKHIDELKKMGANIKVEGRVAIIEGVKRLTGAVVKATDLRAGAAMVIAGLLAEGRTEITSIEHIDRGY
PHIENKLRALGADIKRTTVE

Sequences:

>Translated_420_residues
MERLIINGGNILRGSVEINGAKNAAVAILPAAIMASEGKCVIDNIPDIEDVHCLERILESLGCNTVKIDNNTLEIDSTNV
SNFDASTEDVRRMRASYYFIGALLARFKQAKVVLPGGCPIGVRPIDQHIKGFEALGAEVIIEHGAVIVKAKKLQGTNIFF
DVVSVGATINVMIAATLADGVTTLENVAKEPHVVDVANFLNSMGANIKGAGTDIIRIQGVEKLKGCSYSVIPDQIEAGTF
MIAAVATRGDVYVRNVIPKHLESISAKLKEMGAVIEEDDDCIRVCASDELKAVNVKTTPYPGFPTDIQQPMSALLSVIYG
KSIVTESIWENRHKHIDELKKMGANIKVEGRVAIIEGVKRLTGAVVKATDLRAGAAMVIAGLLAEGRTEITSIEHIDRGY
PHIENKLRALGADIKRTTVE
>Mature_420_residues
MERLIINGGNILRGSVEINGAKNAAVAILPAAIMASEGKCVIDNIPDIEDVHCLERILESLGCNTVKIDNNTLEIDSTNV
SNFDASTEDVRRMRASYYFIGALLARFKQAKVVLPGGCPIGVRPIDQHIKGFEALGAEVIIEHGAVIVKAKKLQGTNIFF
DVVSVGATINVMIAATLADGVTTLENVAKEPHVVDVANFLNSMGANIKGAGTDIIRIQGVEKLKGCSYSVIPDQIEAGTF
MIAAVATRGDVYVRNVIPKHLESISAKLKEMGAVIEEDDDCIRVCASDELKAVNVKTTPYPGFPTDIQQPMSALLSVIYG
KSIVTESIWENRHKHIDELKKMGANIKVEGRVAIIEGVKRLTGAVVKATDLRAGAAMVIAGLLAEGRTEITSIEHIDRGY
PHIENKLRALGADIKRTTVE

Specific function: Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine [H]

COG id: COG0766

COG function: function code M; UDP-N-acetylglucosamine enolpyruvyl transferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family. MurA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789580, Length=422, Percent_Identity=47.6303317535545, Blast_Score=376, Evalue=1e-105,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001986
- InterPro:   IPR013792
- InterPro:   IPR005750 [H]

Pfam domain/function: PF00275 EPSP_synthase [H]

EC number: =2.5.1.7 [H]

Molecular weight: Translated: 45155; Mature: 45155

Theoretical pI: Translated: 6.26; Mature: 6.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MERLIINGGNILRGSVEINGAKNAAVAILPAAIMASEGKCVIDNIPDIEDVHCLERILES
CCEEEEECCCEEEEEEEECCCCCCEEEEEHHHHHCCCCCEEECCCCCCHHHHHHHHHHHH
LGCNTVKIDNNTLEIDSTNVSNFDASTEDVRRMRASYYFIGALLARFKQAKVVLPGGCPI
CCCCEEEECCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCEEECCCCCC
GVRPIDQHIKGFEALGAEVIIEHGAVIVKAKKLQGTNIFFDVVSVGATINVMIAATLADG
CCCHHHHHHHHHHHHCHHHEEECCEEEEEEEECCCCEEEEEHHHCCCEEEEEEEEEHHHH
VTTLENVAKEPHVVDVANFLNSMGANIKGAGTDIIRIQGVEKLKGCSYSVIPDQIEAGTF
HHHHHHHHCCCCEEHHHHHHHHHCCCCCCCCCCEEEEECHHHHCCCCEECCCCCCCCCEE
MIAAVATRGDVYVRNVIPKHLESISAKLKEMGAVIEEDDDCIRVCASDELKAVNVKTTPY
EEEEEECCCCEEEHHHHHHHHHHHHHHHHHHCCHHCCCCHHEEEECCCCEEEEEEECCCC
PGFPTDIQQPMSALLSVIYGKSIVTESIWENRHKHIDELKKMGANIKVEGRVAIIEGVKR
CCCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCCCEEEECEEHHHHHHHH
LTGAVVKATDLRAGAAMVIAGLLAEGRTEITSIEHIDRGYPHIENKLRALGADIKRTTVE
HHHHHEEECCCCCCHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHCCCCHHCCCC
>Mature Secondary Structure
MERLIINGGNILRGSVEINGAKNAAVAILPAAIMASEGKCVIDNIPDIEDVHCLERILES
CCEEEEECCCEEEEEEEECCCCCCEEEEEHHHHHCCCCCEEECCCCCCHHHHHHHHHHHH
LGCNTVKIDNNTLEIDSTNVSNFDASTEDVRRMRASYYFIGALLARFKQAKVVLPGGCPI
CCCCEEEECCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCEEECCCCCC
GVRPIDQHIKGFEALGAEVIIEHGAVIVKAKKLQGTNIFFDVVSVGATINVMIAATLADG
CCCHHHHHHHHHHHHCHHHEEECCEEEEEEEECCCCEEEEEHHHCCCEEEEEEEEEHHHH
VTTLENVAKEPHVVDVANFLNSMGANIKGAGTDIIRIQGVEKLKGCSYSVIPDQIEAGTF
HHHHHHHHCCCCEEHHHHHHHHHCCCCCCCCCCEEEEECHHHHCCCCEECCCCCCCCCEE
MIAAVATRGDVYVRNVIPKHLESISAKLKEMGAVIEEDDDCIRVCASDELKAVNVKTTPY
EEEEEECCCCEEEHHHHHHHHHHHHHHHHHHCCHHCCCCHHEEEECCCCEEEEEEECCCC
PGFPTDIQQPMSALLSVIYGKSIVTESIWENRHKHIDELKKMGANIKVEGRVAIIEGVKR
CCCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCCCEEEECEEHHHHHHHH
LTGAVVKATDLRAGAAMVIAGLLAEGRTEITSIEHIDRGYPHIENKLRALGADIKRTTVE
HHHHHEEECCCCCCHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHCCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11792842 [H]