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The map label for this gene is ysgA [H]

Identifier: 187934593

GI number: 187934593

Start: 2568121

End: 2568903

Strand: Reverse

Name: ysgA [H]

Synonym: CLL_A2474

Alternate gene names: 187934593

Gene position: 2568903-2568121 (Counterclockwise)

Preceding gene: 187933826

Following gene: 187935783

Centisome position: 67.6

GC content: 25.16

Gene sequence:

>783_bases
TTGATTTTCATTGAAAGTAAAGAAAATACTATATATAAAGAAGCTAAAAAACTCAAAGAGAGAAAAAATAGAAATAAGAT
AAATAAGTATGTAATTGAGGGATTTAGACTTGTTGATGAAGCTATAAAAGCAAGTTTAGATATAGATTATTTAATATTGA
CTCAAGTGGGATATGAAAAATTAGATAATTATATAAATAAAGATAAGATAGAAAAACAAAAAGTATATTGTATTACAGAT
AATTTGTTTAAAGATTTAACATCAACAGAGAATCCTCAAGGAATAATTGCTATAGTTAATATGGAAAATAAAAATCTAGA
TTTTCAAGGGGATTTTTATTTGTTTTGTGATAAAGTACAAGATCCAGGAAATCTAGGAACTATAATAAGAACTGCTCATG
CAGCTGGTGTAAATGGAATAATACTATCTAAAGGAACTGTAGACATATATAATGAAAAAACAATAAGATCAACAATGGGA
TCACTATTTTATATGCCTATATATTATGATGACAATGAATTTTCATTAATAAAATCATTAAAAAAAGATGGATTTAAGTT
AATAGTTACATCACTAGAAAGTAGTAAAGACTTTTTTAAAGAAGATTTAAAAGGAAAAACTATACTTACAGTTGGTAATG
AAGGAAATGGTGTATCTAATGAGGTCTTAGATTTAGCTGATAGAAGAGTTAAAATACCAATGCCAGGTGGGGCAGAATCT
TTAAATGTGGCTATAGCTACATCTATCATAATTTATGAAAAAATAAGACAAAATTTTAATTAA

Upstream 100 bases:

>100_bases
TTGTAAATGCTAAGGATATAATAGTAGCTATTGGTTCAGCAGAAGATTTAAGTAAACTTGAGGGTATGATAGTAAGATTA
AAATAATTGAGGTGTAGACT

Downstream 100 bases:

>100_bases
ATTTTTAGTATTGAATTTTAATTAGTTTATTTGTATAATTAGAGGGAATTAAATAATTATAAACTGTGAATGAGAGAGTA
GATATTAGGAAATTTTCAGG

Product: RNA methyltransferase, TrmH family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 260; Mature: 260

Protein sequence:

>260_residues
MIFIESKENTIYKEAKKLKERKNRNKINKYVIEGFRLVDEAIKASLDIDYLILTQVGYEKLDNYINKDKIEKQKVYCITD
NLFKDLTSTENPQGIIAIVNMENKNLDFQGDFYLFCDKVQDPGNLGTIIRTAHAAGVNGIILSKGTVDIYNEKTIRSTMG
SLFYMPIYYDDNEFSLIKSLKKDGFKLIVTSLESSKDFFKEDLKGKTILTVGNEGNGVSNEVLDLADRRVKIPMPGGAES
LNVAIATSIIIYEKIRQNFN

Sequences:

>Translated_260_residues
MIFIESKENTIYKEAKKLKERKNRNKINKYVIEGFRLVDEAIKASLDIDYLILTQVGYEKLDNYINKDKIEKQKVYCITD
NLFKDLTSTENPQGIIAIVNMENKNLDFQGDFYLFCDKVQDPGNLGTIIRTAHAAGVNGIILSKGTVDIYNEKTIRSTMG
SLFYMPIYYDDNEFSLIKSLKKDGFKLIVTSLESSKDFFKEDLKGKTILTVGNEGNGVSNEVLDLADRRVKIPMPGGAES
LNVAIATSIIIYEKIRQNFN
>Mature_260_residues
MIFIESKENTIYKEAKKLKERKNRNKINKYVIEGFRLVDEAIKASLDIDYLILTQVGYEKLDNYINKDKIEKQKVYCITD
NLFKDLTSTENPQGIIAIVNMENKNLDFQGDFYLFCDKVQDPGNLGTIIRTAHAAGVNGIILSKGTVDIYNEKTIRSTMG
SLFYMPIYYDDNEFSLIKSLKKDGFKLIVTSLESSKDFFKEDLKGKTILTVGNEGNGVSNEVLDLADRRVKIPMPGGAES
LNVAIATSIIIYEKIRQNFN

Specific function: Unknown

COG id: COG0566

COG function: function code J; rRNA methylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNA methyltransferase TrmH family [H]

Homologues:

Organism=Homo sapiens, GI8922534, Length=158, Percent_Identity=34.1772151898734, Blast_Score=92, Evalue=5e-19,
Organism=Escherichia coli, GI1790623, Length=175, Percent_Identity=30.8571428571429, Blast_Score=91, Evalue=9e-20,
Organism=Escherichia coli, GI1790083, Length=155, Percent_Identity=32.258064516129, Blast_Score=78, Evalue=5e-16,
Organism=Escherichia coli, GI1788935, Length=194, Percent_Identity=26.2886597938144, Blast_Score=78, Evalue=5e-16,
Organism=Saccharomyces cerevisiae, GI6324775, Length=163, Percent_Identity=30.6748466257669, Blast_Score=70, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24666840, Length=271, Percent_Identity=27.3062730627306, Blast_Score=100, Evalue=1e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001537
- InterPro:   IPR013123 [H]

Pfam domain/function: PF00588 SpoU_methylase; PF08032 SpoU_sub_bind [H]

EC number: 2.1.1.- [C]

Molecular weight: Translated: 29528; Mature: 29528

Theoretical pI: Translated: 7.25; Mature: 7.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIFIESKENTIYKEAKKLKERKNRNKINKYVIEGFRLVDEAIKASLDIDYLILTQVGYEK
CEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHCHHH
LDNYINKDKIEKQKVYCITDNLFKDLTSTENPQGIIAIVNMENKNLDFQGDFYLFCDKVQ
HHHHHCCCCCCCCEEEEEEHHHHHHHHCCCCCCEEEEEEEECCCCCCCCCCEEEEEECCC
DPGNLGTIIRTAHAAGVNGIILSKGTVDIYNEKTIRSTMGSLFYMPIYYDDNEFSLIKSL
CCCCHHHHHHHHHHCCCCEEEEECCEEEECCCHHHHHHHCCEEEEEEEEECCHHHHHHHH
KKDGFKLIVTSLESSKDFFKEDLKGKTILTVGNEGNGVSNEVLDLADRRVKIPMPGGAES
HHCCEEEEEEEHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHCCEEEECCCCCCCC
LNVAIATSIIIYEKIRQNFN
EEHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MIFIESKENTIYKEAKKLKERKNRNKINKYVIEGFRLVDEAIKASLDIDYLILTQVGYEK
CEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHCHHH
LDNYINKDKIEKQKVYCITDNLFKDLTSTENPQGIIAIVNMENKNLDFQGDFYLFCDKVQ
HHHHHCCCCCCCCEEEEEEHHHHHHHHCCCCCCEEEEEEEECCCCCCCCCCEEEEEECCC
DPGNLGTIIRTAHAAGVNGIILSKGTVDIYNEKTIRSTMGSLFYMPIYYDDNEFSLIKSL
CCCCHHHHHHHHHHCCCCEEEEECCEEEECCCHHHHHHHCCEEEEEEEEECCHHHHHHHH
KKDGFKLIVTSLESSKDFFKEDLKGKTILTVGNEGNGVSNEVLDLADRRVKIPMPGGAES
HHCCEEEEEEEHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHCCEEEECCCCCCCC
LNVAIATSIIIYEKIRQNFN
EEHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969504; 9384377 [H]