Click here to switch to the map view.

The map label for this gene is xerC [H]

Identifier: 187934545

GI number: 187934545

Start: 2856997

End: 2858004

Strand: Reverse

Name: xerC [H]

Synonym: CLL_A2762

Alternate gene names: 187934545

Gene position: 2858004-2856997 (Counterclockwise)

Preceding gene: 187935072

Following gene: 187935554

Centisome position: 75.2

GC content: 29.66

Gene sequence:

>1008_bases
ATGAGCAACTTAAACGAAGAAGTATCGATAAAATTAGTGGGAAAATTAACATTGTTATTACCTTTTTTAGAACAGAAATT
AGATATGCAACTAGAAGTTAAGAAAGCTATAGATGAAACTTTATATAACTATGAAGTACAAACTAAGTGTACAGATTTAG
TTTGCAGCGATATAGAAGAAAAAGCTCAATTATACCTTGCATGTAAGAAACTAGAAGGTTTGAGTAGCAAGACATTATAT
AATTACAAATTGTTTCTTAATAAGCTAGATCAGTATTTTACTAAACCATGTTCTACTATAAGCACAATGGACTTAAGAAT
GTTCTTAGCTCTACTGGGTAAAGGCAAGAAAGCAAGTACTGTTAATGGATATATCACTTATTTAAAGAACTTTTTCGGAT
GGTTGCAAAATGAGGAATATATAATAAAAAATCCTGCTTTTAAATTAAAACAAGCTAAAGTTCCTAAGGTTATTCTTGAA
GGATACAAAGCTGAGAACTTAGAAAAATTAAGAGAAGCTTGCGAAACAAAAAGAGAAAAGGCATTGTTTGAATTATTGGA
TAGTACTGCTTGTAGGATATCTGAAATTCAAAATATAAAACTGCAGGATATTAACTGGAATGAAAAAAGCATTAAAGTTA
CTGGAAAAGGTAGTAAAGAAAGAATTGTATATTTCAGTACAAGAGCTAAACTGGCACTTGAAAATTATCTTAAAAGTAGA
AATGATGATAATAATTCATTATTTATTAGTAAGAAGTTTCATAATCGAACTTTAGGTGTTAGATCCCTTCAAAAAACAAT
AAAAAAGATTAAAGAACGTTCAGGAGTAACAGAAAGAGTTCATACACATAAATTTAGAAGGACTCAAGCAACACGATTAC
TAAACCAAGGAATGCGAATTGAAGGGGTTCAAGGAATTTTAGGGCATACTACGCCAACTACAACTCAAATATATGCACAA
CTTTCACAAGAAAACTTGAAAAATGAATATAGAAGATTGGTAGGTTAA

Upstream 100 bases:

>100_bases
TAAGTTAGGATAAAAAACTGAATAGAGAATGAAGCAGTAGCTATTGTTGTAAAACTTCATTCTCAATAAATAATCAATTT
CAAAAAAGGGGGAAGAAAGA

Downstream 100 bases:

>100_bases
TAATTTAGGAGGAAAGATAATGGAATATATAAATGACATTAATATAAATCAAGCTGTAATTCATGTACTAGATAGAAATG
CAACAGAACCTGTTTTAAAT

Product: phage integrase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 335; Mature: 334

Protein sequence:

>335_residues
MSNLNEEVSIKLVGKLTLLLPFLEQKLDMQLEVKKAIDETLYNYEVQTKCTDLVCSDIEEKAQLYLACKKLEGLSSKTLY
NYKLFLNKLDQYFTKPCSTISTMDLRMFLALLGKGKKASTVNGYITYLKNFFGWLQNEEYIIKNPAFKLKQAKVPKVILE
GYKAENLEKLREACETKREKALFELLDSTACRISEIQNIKLQDINWNEKSIKVTGKGSKERIVYFSTRAKLALENYLKSR
NDDNNSLFISKKFHNRTLGVRSLQKTIKKIKERSGVTERVHTHKFRRTQATRLLNQGMRIEGVQGILGHTTPTTTQIYAQ
LSQENLKNEYRRLVG

Sequences:

>Translated_335_residues
MSNLNEEVSIKLVGKLTLLLPFLEQKLDMQLEVKKAIDETLYNYEVQTKCTDLVCSDIEEKAQLYLACKKLEGLSSKTLY
NYKLFLNKLDQYFTKPCSTISTMDLRMFLALLGKGKKASTVNGYITYLKNFFGWLQNEEYIIKNPAFKLKQAKVPKVILE
GYKAENLEKLREACETKREKALFELLDSTACRISEIQNIKLQDINWNEKSIKVTGKGSKERIVYFSTRAKLALENYLKSR
NDDNNSLFISKKFHNRTLGVRSLQKTIKKIKERSGVTERVHTHKFRRTQATRLLNQGMRIEGVQGILGHTTPTTTQIYAQ
LSQENLKNEYRRLVG
>Mature_334_residues
SNLNEEVSIKLVGKLTLLLPFLEQKLDMQLEVKKAIDETLYNYEVQTKCTDLVCSDIEEKAQLYLACKKLEGLSSKTLYN
YKLFLNKLDQYFTKPCSTISTMDLRMFLALLGKGKKASTVNGYITYLKNFFGWLQNEEYIIKNPAFKLKQAKVPKVILEG
YKAENLEKLREACETKREKALFELLDSTACRISEIQNIKLQDINWNEKSIKVTGKGSKERIVYFSTRAKLALENYLKSRN
DDNNSLFISKKFHNRTLGVRSLQKTIKKIKERSGVTERVHTHKFRRTQATRLLNQGMRIEGVQGILGHTTPTTTQIYAQL
SQENLKNEYRRLVG

Specific function: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The xerC-xerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell div

COG id: COG0582

COG function: function code L; Integrase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family. XerC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790244, Length=224, Percent_Identity=27.6785714285714, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI1789261, Length=271, Percent_Identity=28.4132841328413, Blast_Score=102, Evalue=3e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR010998
- InterPro:   IPR023109
- InterPro:   IPR004107
- InterPro:   IPR011931 [H]

Pfam domain/function: PF02899 Phage_integr_N; PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 38748; Mature: 38616

Theoretical pI: Translated: 10.11; Mature: 10.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNLNEEVSIKLVGKLTLLLPFLEQKLDMQLEVKKAIDETLYNYEVQTKCTDLVCSDIEE
CCCCCCCEEEEHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
KAQLYLACKKLEGLSSKTLYNYKLFLNKLDQYFTKPCSTISTMDLRMFLALLGKGKKAST
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCH
VNGYITYLKNFFGWLQNEEYIIKNPAFKLKQAKVPKVILEGYKAENLEKLREACETKREK
HHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHCCCHHHHHCCCCCHHHHHHHHHHHHHHH
ALFELLDSTACRISEIQNIKLQDINWNEKSIKVTGKGSKERIVYFSTRAKLALENYLKSR
HHHHHHHHHHHHHHHHCCCEEEECCCCCCEEEEECCCCCCEEEEEECHHHHHHHHHHHCC
NDDNNSLFISKKFHNRTLGVRSLQKTIKKIKERSGVTERVHTHKFRRTQATRLLNQGMRI
CCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCE
EGVQGILGHTTPTTTQIYAQLSQENLKNEYRRLVG
ECCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SNLNEEVSIKLVGKLTLLLPFLEQKLDMQLEVKKAIDETLYNYEVQTKCTDLVCSDIEE
CCCCCCEEEEHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
KAQLYLACKKLEGLSSKTLYNYKLFLNKLDQYFTKPCSTISTMDLRMFLALLGKGKKAST
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCH
VNGYITYLKNFFGWLQNEEYIIKNPAFKLKQAKVPKVILEGYKAENLEKLREACETKREK
HHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHCCCHHHHHCCCCCHHHHHHHHHHHHHHH
ALFELLDSTACRISEIQNIKLQDINWNEKSIKVTGKGSKERIVYFSTRAKLALENYLKSR
HHHHHHHHHHHHHHHHCCCEEEECCCCCCEEEEECCCCCCEEEEEECHHHHHHHHHHHCC
NDDNNSLFISKKFHNRTLGVRSLQKTIKKIKERSGVTERVHTHKFRRTQATRLLNQGMRI
CCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCE
EGVQGILGHTTPTTTQIYAQLSQENLKNEYRRLVG
ECCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12235376 [H]