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The map label for this gene is pheA [H]

Identifier: 187934308

GI number: 187934308

Start: 3249159

End: 3250301

Strand: Reverse

Name: pheA [H]

Synonym: CLL_A3140

Alternate gene names: 187934308

Gene position: 3250301-3249159 (Counterclockwise)

Preceding gene: 187935282

Following gene: 187932786

Centisome position: 85.53

GC content: 24.15

Gene sequence:

>1143_bases
ATGTCAGGATTAGAGGATTACAGAAATAGTATAGATGAAATAGATCAAAAGATAACTGAATTGTTTGAGCAGAGAATGGA
TGTTGTTCTTAAAGTAGGGGAATATAAGAAAAAAAATAATTTGCATATATTTAATAAGAATAGAGAAGATGAAGTTATTA
AGAAGAATTTAGGTTATCTAAAAAATCAAGATTATATTGAAGAAACAGAAAAATTCTTTGAAAGATTAATGGAAATATCA
AGGCAGCTTCAAAGTAGAAAAATGATAGAAGAAGATTTATTAAAAGAGAAAAAATCAAATAGCAATATTAACGTTTATGA
AGAAAAAAAGATTGGATTTTATGGTGCACAAGGATCTTTTACTGAAGAAGCAATGATTAAATATTTTGGTGAAGATAGAA
ATTCTAAATCATATGAAGAATTTGAAGATGTATTTTTAGCAATTAAAAATGATGAAATTAATTATGGAATACTTCCAATA
GAAAATTCATCAACAGGAGCAATTTCTAGTGTATATGATCTTTTGTATAAATATGGATTCTTTATAAATGGAGAGGTATG
TATAAAAATAAATCAAAATTTAATTGGGATAGATGGAAGCAATTTAAATGAAATTAAAGAAATATACTCACATGCTCAAG
GATTTGAACAAAGTTCAGATTTCTTAAAGAAATATAATGAGTGGAAGCTGATACCATTCCATAGTACAGCTAGTAGTGCT
AAATTAATCAAAGAGTTAGAGGATAAATCAAAAGCTGCAATAGGTAGTAAAAGAGTAGCTAATATATATAATTTAGAAAT
TATTAAAGAAAATATAAATAATCAAACAGAAAATTTCACAAGGTTTATAATAATTTCTAAACAATTAGAAGAAAATAAAA
ATTCCAATAAGATTAGTGTAGTATTTTCACTTGAAGATAAAGCTGGTACATTATATAAGTTATTAAGACATTTTGCAGAA
AACAATATAAATATGATTAAAATAGAATCAAGACCAATGAAAAATGGTCCTTGGAAGTATTTTTTATATGTTGATTTTGA
AGGTGATTTATTTTCAGAAAAAGTTAAAAAATCTTTATATTTAATTGAACAAAGTAGTGCTTACTTCAAGTTATTAGGAA
CATATGAAAAAAATAAATATTAA

Upstream 100 bases:

>100_bases
AATATATTTTTTAGAAAAGATTAGCTTTTCAAGTTAAACTTTCAACTAAAAGAGCGTGTAGTAACCACTTTTTAAATATT
AAAAATAAGAGGTGTGACAT

Downstream 100 bases:

>100_bases
ACAAAGAAAAGGGGGCATAAATAGTGAATTTTTATGGAGTACTAGGTGAAAAATTATCACATTCTATATCGCCAATGATT
CATAATAAAATTTTTTCACT

Product: P-protein

Products: NA

Alternate protein names: Chorismate mutase; CM; Prephenate dehydratase; PDT [H]

Number of amino acids: Translated: 380; Mature: 379

Protein sequence:

>380_residues
MSGLEDYRNSIDEIDQKITELFEQRMDVVLKVGEYKKKNNLHIFNKNREDEVIKKNLGYLKNQDYIEETEKFFERLMEIS
RQLQSRKMIEEDLLKEKKSNSNINVYEEKKIGFYGAQGSFTEEAMIKYFGEDRNSKSYEEFEDVFLAIKNDEINYGILPI
ENSSTGAISSVYDLLYKYGFFINGEVCIKINQNLIGIDGSNLNEIKEIYSHAQGFEQSSDFLKKYNEWKLIPFHSTASSA
KLIKELEDKSKAAIGSKRVANIYNLEIIKENINNQTENFTRFIIISKQLEENKNSNKISVVFSLEDKAGTLYKLLRHFAE
NNINMIKIESRPMKNGPWKYFLYVDFEGDLFSEKVKKSLYLIEQSSAYFKLLGTYEKNKY

Sequences:

>Translated_380_residues
MSGLEDYRNSIDEIDQKITELFEQRMDVVLKVGEYKKKNNLHIFNKNREDEVIKKNLGYLKNQDYIEETEKFFERLMEIS
RQLQSRKMIEEDLLKEKKSNSNINVYEEKKIGFYGAQGSFTEEAMIKYFGEDRNSKSYEEFEDVFLAIKNDEINYGILPI
ENSSTGAISSVYDLLYKYGFFINGEVCIKINQNLIGIDGSNLNEIKEIYSHAQGFEQSSDFLKKYNEWKLIPFHSTASSA
KLIKELEDKSKAAIGSKRVANIYNLEIIKENINNQTENFTRFIIISKQLEENKNSNKISVVFSLEDKAGTLYKLLRHFAE
NNINMIKIESRPMKNGPWKYFLYVDFEGDLFSEKVKKSLYLIEQSSAYFKLLGTYEKNKY
>Mature_379_residues
SGLEDYRNSIDEIDQKITELFEQRMDVVLKVGEYKKKNNLHIFNKNREDEVIKKNLGYLKNQDYIEETEKFFERLMEISR
QLQSRKMIEEDLLKEKKSNSNINVYEEKKIGFYGAQGSFTEEAMIKYFGEDRNSKSYEEFEDVFLAIKNDEINYGILPIE
NSSTGAISSVYDLLYKYGFFINGEVCIKINQNLIGIDGSNLNEIKEIYSHAQGFEQSSDFLKKYNEWKLIPFHSTASSAK
LIKELEDKSKAAIGSKRVANIYNLEIIKENINNQTENFTRFIIISKQLEENKNSNKISVVFSLEDKAGTLYKLLRHFAEN
NINMIKIESRPMKNGPWKYFLYVDFEGDLFSEKVKKSLYLIEQSSAYFKLLGTYEKNKY

Specific function: L-phenylalanine biosynthesis. [C]

COG id: COG0077

COG function: function code E; Prephenate dehydratase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 prephenate dehydratase domain [H]

Homologues:

Organism=Escherichia coli, GI1788951, Length=377, Percent_Identity=28.1167108753316, Blast_Score=178, Evalue=5e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002912
- InterPro:   IPR008242
- InterPro:   IPR002701
- InterPro:   IPR020822
- InterPro:   IPR010957
- InterPro:   IPR001086
- InterPro:   IPR018528 [H]

Pfam domain/function: PF01842 ACT; PF01817 CM_2; PF00800 PDT [H]

EC number: =5.4.99.5; =4.2.1.51 [H]

Molecular weight: Translated: 44545; Mature: 44414

Theoretical pI: Translated: 5.65; Mature: 5.65

Prosite motif: PS00857 PREPHENATE_DEHYDR_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGLEDYRNSIDEIDQKITELFEQRMDVVLKVGEYKKKNNLHIFNKNREDEVIKKNLGYL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCHHHHHHHHHCCC
KNQDYIEETEKFFERLMEISRQLQSRKMIEEDLLKEKKSNSNINVYEEKKIGFYGAQGSF
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCEEECCCCCC
TEEAMIKYFGEDRNSKSYEEFEDVFLAIKNDEINYGILPIENSSTGAISSVYDLLYKYGF
HHHHHHHHHCCCCCCCCHHHHHHHEEEEECCCCEEEEEEECCCCCCHHHHHHHHHHHHCC
FINGEVCIKINQNLIGIDGSNLNEIKEIYSHAQGFEQSSDFLKKYNEWKLIPFHSTASSA
EECCEEEEEECCCEEECCCCCHHHHHHHHHHHCCCCHHHHHHHHCCCCEEEEECCCCHHH
KLIKELEDKSKAAIGSKRVANIYNLEIIKENINNQTENFTRFIIISKQLEENKNSNKISV
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCEEEEEEEEHHHHCCCCCCEEEE
VFSLEDKAGTLYKLLRHFAENNINMIKIESRPMKNGPWKYFLYVDFEGDLFSEKVKKSLY
EEEECCCCCHHHHHHHHHHHCCCEEEEEECCCCCCCCEEEEEEEEECCCHHHHHHHHHHE
LIEQSSAYFKLLGTYEKNKY
EEECCCCEEEEEECCCCCCC
>Mature Secondary Structure 
SGLEDYRNSIDEIDQKITELFEQRMDVVLKVGEYKKKNNLHIFNKNREDEVIKKNLGYL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCHHHHHHHHHCCC
KNQDYIEETEKFFERLMEISRQLQSRKMIEEDLLKEKKSNSNINVYEEKKIGFYGAQGSF
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCEEECCCCCC
TEEAMIKYFGEDRNSKSYEEFEDVFLAIKNDEINYGILPIENSSTGAISSVYDLLYKYGF
HHHHHHHHHCCCCCCCCHHHHHHHEEEEECCCCEEEEEEECCCCCCHHHHHHHHHHHHCC
FINGEVCIKINQNLIGIDGSNLNEIKEIYSHAQGFEQSSDFLKKYNEWKLIPFHSTASSA
EECCEEEEEECCCEEECCCCCHHHHHHHHHHHCCCCHHHHHHHHCCCCEEEEECCCCHHH
KLIKELEDKSKAAIGSKRVANIYNLEIIKENINNQTENFTRFIIISKQLEENKNSNKISV
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCEEEEEEEEHHHHCCCCCCEEEE
VFSLEDKAGTLYKLLRHFAENNINMIKIESRPMKNGPWKYFLYVDFEGDLFSEKVKKSLY
EEEECCCCCHHHHHHHHHHHCCCEEEEEECCCCCCCCEEEEEEEEECCCHHHHHHHHHHE
LIEQSSAYFKLLGTYEKNKY
EEECCCCEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]