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The map label for this gene is fhuG [H]

Identifier: 187934017

GI number: 187934017

Start: 2211272

End: 2212288

Strand: Reverse

Name: fhuG [H]

Synonym: CLL_A2114

Alternate gene names: 187934017

Gene position: 2212288-2211272 (Counterclockwise)

Preceding gene: 187933044

Following gene: 187934656

Centisome position: 58.21

GC content: 30.19

Gene sequence:

>1017_bases
ATGATAAATATAGATAAAAATAAAAGATTTACATTAATTATAGGTGTTTTAATGATACTAATAATTACTACAATTTTGAT
TGGTTTAAATATGGGCTCTCTAGCTATAGATCCATCAGATGTTATAAAAACTTTAATGGGGCAAGGCAGTAAAAGTCATG
AAATTGCTATATTTAAGTTAAGGTTACCAAGAATAGTAATTGGAATATTAGTTGGTACAGCTTTAGCTATAGCAGGTACT
ATTTTACAAGGAGTTACTAAAAATGATTTAGCAGACTCAGGAATACTAGGAATAAATTCGGGAGCAGCATTATTTGTTGT
CATATATATTTATATTATGAATGGAAATATATATGATGGTATAAGCAATATGACTATATTTACAATGCCAATAGTTGCTT
TAAGTGGAGCTATATTTGGAGCATTTTTAATTTATATGCTAGCATGGAAAAATGGTATAAATTCATCAAGGTTATTGCTA
ATAGGTATAGGTATAAATGTAGCATTTACATCTATACTTACAATATTCCAATTAAGATTTACAACACAAGAATTTAATAG
AGTAATGGCATGGACTTCGGGAAGTATATGGGGTGCAAGTTGGAAATATGTATTAGCAGTTCTGCCATTTATATTAATAT
TTACATTGCTAACAATTTACAAGGCTAGATATTTAGATGTATTAAATTTAGGTGACGAAGTAGCAACGGGATTAGGCGTA
GAAGTTGAAAAAGAGAGAAGAAAGTTAATAATATATGCAGTTATTTTAGCAGGAGTAGCAACATCTGTGGCAGGCAGTAT
AGCCTTTTTAGGATTGGTAGCGCCTCACATAGCTAGGAAACTAGTTGGACCAAAACATAATAAATTAATCCTGACATCTG
CACTTGTTGGGAGTTTAATATTATTGATTGGAGATACTATAGCAAGAAATATAATAGCTCCTATGGAACTTCCTGTAGGA
ATAGTTGTAGCAATAATAGGTGTTCCATATTTTATTTATCTTATGTTATCAGAATAG

Upstream 100 bases:

>100_bases
TAGAATGATTAATCCTCCATATGAAACTCCAATTGGTTCTTTAACTGCATTATTAGGAGTTCCTATGTTTATATATCTTG
TTAGAAAGGATAAGAAATAG

Downstream 100 bases:

>100_bases
ATAAAAATAATTAATTTAAACAAAGGAGAAAGAAATGAACTGTATAAGTACTAAGAACTTGAATATTTCCTATGGAAATT
TAGATATAGTTAAAAATTTA

Product: ferrichrome transport system permease protein FhuG

Products: ADP; phosphate; iron dicitrate [Cytoplasm] [C]

Alternate protein names: Ferric hydroxamate uptake protein G; Ferrichrome transport system permease protein fhuG; Iron(III)-hydroxamate import system permease protein fhuG [H]

Number of amino acids: Translated: 338; Mature: 338

Protein sequence:

>338_residues
MINIDKNKRFTLIIGVLMILIITTILIGLNMGSLAIDPSDVIKTLMGQGSKSHEIAIFKLRLPRIVIGILVGTALAIAGT
ILQGVTKNDLADSGILGINSGAALFVVIYIYIMNGNIYDGISNMTIFTMPIVALSGAIFGAFLIYMLAWKNGINSSRLLL
IGIGINVAFTSILTIFQLRFTTQEFNRVMAWTSGSIWGASWKYVLAVLPFILIFTLLTIYKARYLDVLNLGDEVATGLGV
EVEKERRKLIIYAVILAGVATSVAGSIAFLGLVAPHIARKLVGPKHNKLILTSALVGSLILLIGDTIARNIIAPMELPVG
IVVAIIGVPYFIYLMLSE

Sequences:

>Translated_338_residues
MINIDKNKRFTLIIGVLMILIITTILIGLNMGSLAIDPSDVIKTLMGQGSKSHEIAIFKLRLPRIVIGILVGTALAIAGT
ILQGVTKNDLADSGILGINSGAALFVVIYIYIMNGNIYDGISNMTIFTMPIVALSGAIFGAFLIYMLAWKNGINSSRLLL
IGIGINVAFTSILTIFQLRFTTQEFNRVMAWTSGSIWGASWKYVLAVLPFILIFTLLTIYKARYLDVLNLGDEVATGLGV
EVEKERRKLIIYAVILAGVATSVAGSIAFLGLVAPHIARKLVGPKHNKLILTSALVGSLILLIGDTIARNIIAPMELPVG
IVVAIIGVPYFIYLMLSE
>Mature_338_residues
MINIDKNKRFTLIIGVLMILIITTILIGLNMGSLAIDPSDVIKTLMGQGSKSHEIAIFKLRLPRIVIGILVGTALAIAGT
ILQGVTKNDLADSGILGINSGAALFVVIYIYIMNGNIYDGISNMTIFTMPIVALSGAIFGAFLIYMLAWKNGINSSRLLL
IGIGINVAFTSILTIFQLRFTTQEFNRVMAWTSGSIWGASWKYVLAVLPFILIFTLLTIYKARYLDVLNLGDEVATGLGV
EVEKERRKLIIYAVILAGVATSVAGSIAFLGLVAPHIARKLVGPKHNKLILTSALVGSLILLIGDTIARNIIAPMELPVG
IVVAIIGVPYFIYLMLSE

Specific function: Part of the ABC transporter complex fhuBGCD involved in iron(3+)-hydroxamate import. Responsible for the translocation of the substrate across the membrane [H]

COG id: COG0609

COG function: function code P; ABC-type Fe3+-siderophore transport system, permease component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790740, Length=310, Percent_Identity=34.5161290322581, Blast_Score=184, Evalue=9e-48,
Organism=Escherichia coli, GI1786804, Length=311, Percent_Identity=32.475884244373, Blast_Score=147, Evalue=8e-37,
Organism=Escherichia coli, GI1786347, Length=283, Percent_Identity=33.5689045936396, Blast_Score=136, Evalue=2e-33,
Organism=Escherichia coli, GI1790741, Length=300, Percent_Identity=32, Blast_Score=125, Evalue=4e-30,
Organism=Escherichia coli, GI1788004, Length=310, Percent_Identity=30.3225806451613, Blast_Score=121, Evalue=6e-29,
Organism=Escherichia coli, GI1786805, Length=307, Percent_Identity=29.6416938110749, Blast_Score=102, Evalue=4e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000522 [H]

Pfam domain/function: PF01032 FecCD [H]

EC number: NA

Molecular weight: Translated: 36447; Mature: 36447

Theoretical pI: Translated: 10.07; Mature: 10.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MINIDKNKRFTLIIGVLMILIITTILIGLNMGSLAIDPSDVIKTLMGQGSKSHEIAIFKL
CCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEECHHHHHHHHHCCCCCCCCEEEEEE
RLPRIVIGILVGTALAIAGTILQGVTKNDLADSGILGINSGAALFVVIYIYIMNGNIYDG
EHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEECCCCHHHHHHHHHHHCCCCCCCC
ISNMTIFTMPIVALSGAIFGAFLIYMLAWKNGINSSRLLLIGIGINVAFTSILTIFQLRF
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECHHHHHHHHHHHHHHHH
TTQEFNRVMAWTSGSIWGASWKYVLAVLPFILIFTLLTIYKARYLDVLNLGDEVATGLGV
HHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCC
EVEKERRKLIIYAVILAGVATSVAGSIAFLGLVAPHIARKLVGPKHNKLILTSALVGSLI
EEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHH
LLIGDTIARNIIAPMELPVGIVVAIIGVPYFIYLMLSE
HHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHEECC
>Mature Secondary Structure
MINIDKNKRFTLIIGVLMILIITTILIGLNMGSLAIDPSDVIKTLMGQGSKSHEIAIFKL
CCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEECHHHHHHHHHCCCCCCCCEEEEEE
RLPRIVIGILVGTALAIAGTILQGVTKNDLADSGILGINSGAALFVVIYIYIMNGNIYDG
EHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEECCCCHHHHHHHHHHHCCCCCCCC
ISNMTIFTMPIVALSGAIFGAFLIYMLAWKNGINSSRLLLIGIGINVAFTSILTIFQLRF
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECHHHHHHHHHHHHHHHH
TTQEFNRVMAWTSGSIWGASWKYVLAVLPFILIFTLLTIYKARYLDVLNLGDEVATGLGV
HHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCC
EVEKERRKLIIYAVILAGVATSVAGSIAFLGLVAPHIARKLVGPKHNKLILTSALVGSLI
EEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHH
LLIGDTIARNIIAPMELPVGIVVAIIGVPYFIYLMLSE
HHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; iron dicitrate [Periplasm]; H2O [C]

Specific reaction: ATP + iron dicitrate [Periplasm] + H2O = ADP + phosphate + iron dicitrate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9639930; 9384377 [H]