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The map label for this gene is arsC1 [H]

Identifier: 187933687

GI number: 187933687

Start: 2362884

End: 2363288

Strand: Reverse

Name: arsC1 [H]

Synonym: CLL_A2292

Alternate gene names: 187933687

Gene position: 2363288-2362884 (Counterclockwise)

Preceding gene: 187934741

Following gene: 187934821

Centisome position: 62.19

GC content: 28.4

Gene sequence:

>405_bases
ATGAAAACAAAAGTTGCATTTATATGTGTGCACAATTCATGTAGGTCACAAATGGCAGAGGCATTAGGAAAACTCTATGG
AAGTGATGTATTTGAAAGTTATTCAGCAGGCACAGAAGTTAAACCAGAAATTAATCAAGATGCAGTAAGAATAATTAAAA
AATTATACAATGTAGATATGAATAAGGATCAAAAGTCAAAATTGTTAAGTGATATACCTAAAGTTGATATAGTAATAAAG
ATGGGATGTAATGTAGTATGTCCATATCTTCCAGCTAAACATACTGAAGATTGGGGATTAGAAGATCCGACTAATAAAAA
TTATGAAGAGTTTGTAAAAATAGCAAAATCAATTGAAGAAAAAATACTTGATTTAGCTAAAAGAATAAAAATGAATGAGA
TTTAA

Upstream 100 bases:

>100_bases
TTTAATGAATATAGTTACAGAAACAGAAGATTGTATTTGTAATAATATATTAAAATGTAAAGATGATAAATAGATTAGCA
TTTAGAGAGAGGTAAAGCAT

Downstream 100 bases:

>100_bases
AAATAGTTTTGTTTTAAATGTTTACTTATGTATATAGGATAATTTAAAAAATAGATTCGCAAAATATGCTAAAGCTAACT
GATAAGACTATAATAAATTT

Product: arsenate reductase

Products: NA

Alternate protein names: Arsenate reductase 1; Arsenical pump modifier 1; Low molecular weight protein-tyrosine-phosphatase 1 [H]

Number of amino acids: Translated: 134; Mature: 134

Protein sequence:

>134_residues
MKTKVAFICVHNSCRSQMAEALGKLYGSDVFESYSAGTEVKPEINQDAVRIIKKLYNVDMNKDQKSKLLSDIPKVDIVIK
MGCNVVCPYLPAKHTEDWGLEDPTNKNYEEFVKIAKSIEEKILDLAKRIKMNEI

Sequences:

>Translated_134_residues
MKTKVAFICVHNSCRSQMAEALGKLYGSDVFESYSAGTEVKPEINQDAVRIIKKLYNVDMNKDQKSKLLSDIPKVDIVIK
MGCNVVCPYLPAKHTEDWGLEDPTNKNYEEFVKIAKSIEEKILDLAKRIKMNEI
>Mature_134_residues
MKTKVAFICVHNSCRSQMAEALGKLYGSDVFESYSAGTEVKPEINQDAVRIIKKLYNVDMNKDQKSKLLSDIPKVDIVIK
MGCNVVCPYLPAKHTEDWGLEDPTNKNYEEFVKIAKSIEEKILDLAKRIKMNEI

Specific function: Reduces arsenate [As(V)] to arsenite [As(III)] and dephosphorylates tyrosine phosphorylated proteins, low-MW aryl phosphates and natural and synthetic acyl phosphates. Could switch between different functions in different circumstances [H]

COG id: COG0394

COG function: function code T; Protein-tyrosine-phosphatase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the low molecular weight phosphotyrosine protein phosphatase superfamily. ArsC family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014064
- InterPro:   IPR017867 [H]

Pfam domain/function: PF01451 LMWPc [H]

EC number: =3.1.3.48 [H]

Molecular weight: Translated: 15241; Mature: 15241

Theoretical pI: Translated: 7.92; Mature: 7.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.0 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
6.7 %Cys+Met (Translated Protein)
3.0 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
6.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTKVAFICVHNSCRSQMAEALGKLYGSDVFESYSAGTEVKPEINQDAVRIIKKLYNVDM
CCCEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCC
NKDQKSKLLSDIPKVDIVIKMGCNVVCPYLPAKHTEDWGLEDPTNKNYEEFVKIAKSIEE
CCCHHHHHHHHCCCCEEEEECCCCEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
KILDLAKRIKMNEI
HHHHHHHHHHHCCC
>Mature Secondary Structure
MKTKVAFICVHNSCRSQMAEALGKLYGSDVFESYSAGTEVKPEINQDAVRIIKKLYNVDM
CCCEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCC
NKDQKSKLLSDIPKVDIVIKMGCNVVCPYLPAKHTEDWGLEDPTNKNYEEFVKIAKSIEE
CCCHHHHHHHHCCCCEEEEECCCCEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
KILDLAKRIKMNEI
HHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA