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The map label for this gene is aroE [H]

Identifier: 187932786

GI number: 187932786

Start: 3248323

End: 3249135

Strand: Reverse

Name: aroE [H]

Synonym: CLL_A3139

Alternate gene names: 187932786

Gene position: 3249135-3248323 (Counterclockwise)

Preceding gene: 187934308

Following gene: 187934749

Centisome position: 85.5

GC content: 25.09

Gene sequence:

>813_bases
GTGAATTTTTATGGAGTACTAGGTGAAAAATTATCACATTCTATATCGCCAATGATTCATAATAAAATTTTTTCACTTTT
AGATATTAAAGGGGCATATAAAATATTTGAAGTTGAAAAAGAAGATTTAAAGAAATTTGCAGACTCATTAAGAGTATTAA
AAATTAAAGGGTGTAATGTAACCATCCCATATAAAGAAGATATAATGAAATATTTAGATGAAATATCACCTGAAGCAAAA
AAAATAAAAGCAATAAATACAATACTATTAAAAAATAATAAATTATATGGATTTAATAGTGATTATTATGGATTTAATAG
TATATTACTCAGGAACAATATAGAAGCTAATGATAAAGTAGCTATGGTACTAGGGACTGGTGGGGCATCAAAAGCAGCAG
TAACTTTATTATTAGATAAAGGTGTTAAAAAAATATATTTAGTTTCTAGGAGTAAAAAATCAATTCCTTTGGATCTGGAT
AATAGAATTGAATATAGAATTTATGAGGACATAGGTAATGTAAAAGGTGATATATTGATAAATGCAACTCCAGTGGGAAT
GTATCCTAATGTAGATAATAATCCTGTTGATGAAAAGATTATTAATAATTTTGATGTATTAATAGATTTAATATATAATC
CAAGAGATACTAAATTTCTTCAATGTGGAAAAAAATTAAATAAAAAGATTTGTGGTGGTTTAGAAATGCTTGTAGGACAA
GCGATTAAGTCATCAGAAATTTGGCATGATATATCTATAAATTCTGATATACAAGAGAAAATATATTCATATATAGATGA
AGAATTTAGATAG

Upstream 100 bases:

>100_bases
AAAAATCTTTATATTTAATTGAACAAAGTAGTGCTTACTTCAAGTTATTAGGAACATATGAAAAAAATAAATATTAAACA
AAGAAAAGGGGGCATAAATA

Downstream 100 bases:

>100_bases
AGGAGATTATATTATGAAAAATAAGATATTTTTAATAGGAATGCCTGGATGTGGAAAATCTACAATTGGAGAAATTATAG
CCAAAGAATTAATGTTAAAG

Product: shikimate 5-dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 270; Mature: 270

Protein sequence:

>270_residues
MNFYGVLGEKLSHSISPMIHNKIFSLLDIKGAYKIFEVEKEDLKKFADSLRVLKIKGCNVTIPYKEDIMKYLDEISPEAK
KIKAINTILLKNNKLYGFNSDYYGFNSILLRNNIEANDKVAMVLGTGGASKAAVTLLLDKGVKKIYLVSRSKKSIPLDLD
NRIEYRIYEDIGNVKGDILINATPVGMYPNVDNNPVDEKIINNFDVLIDLIYNPRDTKFLQCGKKLNKKICGGLEMLVGQ
AIKSSEIWHDISINSDIQEKIYSYIDEEFR

Sequences:

>Translated_270_residues
MNFYGVLGEKLSHSISPMIHNKIFSLLDIKGAYKIFEVEKEDLKKFADSLRVLKIKGCNVTIPYKEDIMKYLDEISPEAK
KIKAINTILLKNNKLYGFNSDYYGFNSILLRNNIEANDKVAMVLGTGGASKAAVTLLLDKGVKKIYLVSRSKKSIPLDLD
NRIEYRIYEDIGNVKGDILINATPVGMYPNVDNNPVDEKIINNFDVLIDLIYNPRDTKFLQCGKKLNKKICGGLEMLVGQ
AIKSSEIWHDISINSDIQEKIYSYIDEEFR
>Mature_270_residues
MNFYGVLGEKLSHSISPMIHNKIFSLLDIKGAYKIFEVEKEDLKKFADSLRVLKIKGCNVTIPYKEDIMKYLDEISPEAK
KIKAINTILLKNNKLYGFNSDYYGFNSILLRNNIEANDKVAMVLGTGGASKAAVTLLLDKGVKKIYLVSRSKKSIPLDLD
NRIEYRIYEDIGNVKGDILINATPVGMYPNVDNNPVDEKIINNFDVLIDLIYNPRDTKFLQCGKKLNKKICGGLEMLVGQ
AIKSSEIWHDISINSDIQEKIYSYIDEEFR

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; fourth step. [C]

COG id: COG0169

COG function: function code E; Shikimate 5-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the shikimate dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1787983, Length=267, Percent_Identity=28.8389513108614, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI1789675, Length=257, Percent_Identity=29.1828793774319, Blast_Score=95, Evalue=5e-21,
Organism=Saccharomyces cerevisiae, GI6320332, Length=269, Percent_Identity=28.2527881040892, Blast_Score=101, Evalue=2e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR011342
- InterPro:   IPR013708
- InterPro:   IPR022893
- InterPro:   IPR006151 [H]

Pfam domain/function: PF01488 Shikimate_DH; PF08501 Shikimate_dh_N [H]

EC number: =1.1.1.25 [H]

Molecular weight: Translated: 30671; Mature: 30671

Theoretical pI: Translated: 8.66; Mature: 8.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNFYGVLGEKLSHSISPMIHNKIFSLLDIKGAYKIFEVEKEDLKKFADSLRVLKIKGCNV
CCCHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCEEEECCHHHHHHHHHCEEEEEEECCEE
TIPYKEDIMKYLDEISPEAKKIKAINTILLKNNKLYGFNSDYYGFNSILLRNNIEANDKV
ECCCHHHHHHHHHHCCCHHHHHHHHHEEEEECCEEECCCCCCCCCEEEEEECCCCCCCEE
AMVLGTGGASKAAVTLLLDKGVKKIYLVSRSKKSIPLDLDNRIEYRIYEDIGNVKGDILI
EEEEECCCCCHHEEEEEECCCCEEEEEEECCCCCCCCCCCCCEEEEEEHHHCCCCCCEEE
NATPVGMYPNVDNNPVDEKIINNFDVLIDLIYNPRDTKFLQCGKKLNKKICGGLEMLVGQ
EEECCCCCCCCCCCCCHHHHHCCHHHEEHEEECCCCHHHHHHHHHHHHHHHCHHHHHHHH
AIKSSEIWHDISINSDIQEKIYSYIDEEFR
HHHCCCCEEEECCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNFYGVLGEKLSHSISPMIHNKIFSLLDIKGAYKIFEVEKEDLKKFADSLRVLKIKGCNV
CCCHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCEEEECCHHHHHHHHHCEEEEEEECCEE
TIPYKEDIMKYLDEISPEAKKIKAINTILLKNNKLYGFNSDYYGFNSILLRNNIEANDKV
ECCCHHHHHHHHHHCCCHHHHHHHHHEEEEECCEEECCCCCCCCCEEEEEECCCCCCCEE
AMVLGTGGASKAAVTLLLDKGVKKIYLVSRSKKSIPLDLDNRIEYRIYEDIGNVKGDILI
EEEEECCCCCHHEEEEEECCCCEEEEEEECCCCCCCCCCCCCEEEEEEHHHCCCCCCEEE
NATPVGMYPNVDNNPVDEKIINNFDVLIDLIYNPRDTKFLQCGKKLNKKICGGLEMLVGQ
EEECCCCCCCCCCCCCHHHHHCCHHHEEHEEECCCCHHHHHHHHHHHHHHHCHHHHHHHH
AIKSSEIWHDISINSDIQEKIYSYIDEEFR
HHHCCCCEEEECCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA