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The map label for this gene is adrA [H]

Identifier: 187932755

GI number: 187932755

Start: 2883932

End: 2885230

Strand: Reverse

Name: adrA [H]

Synonym: CLL_A2804

Alternate gene names: 187932755

Gene position: 2885230-2883932 (Counterclockwise)

Preceding gene: 187935626

Following gene: 187935049

Centisome position: 75.92

GC content: 27.33

Gene sequence:

>1299_bases
ATGAGCAAAAAAAATACAGAGCCTATTTCAAATTTTATAGGTAGTTATAAACAGCAAATAGGATATCTAGACAAGATGCC
AGTAGCAGTTGCTATTATAAAAGTAGAAGTAAATGAAATTGGTGAACCCAGTGACTTTATATTTGTTTATGTAAATGAGG
CATTAACAAAAATTGAAAATCTTTCAAAAGAAAAGTTGCTAGGTTCTTCTTTTTATGAAGTTTTTAAAAATGGTGAGAAA
AAGTGGCTGTATGAATATTGGAAAACAGCATATAATGGAACGAACAAAGAGATATATGAATATAGCAAGGCGCTTAATAA
GTTCTTATCTATTTCCTGTTATCAACCAAGTTATGGCTATTGTGGATGTGTATTAAAGGATATGTCCGATAAAATGATAT
TAGAGGCAGAGAACACTAAAAAACAAAAAAGAATTGATATAATTTTAAAGAATTCTATTGATGCTATATTTGATTTAGAT
TTAAAAACAAATACTATTTTGAATGAATCAGTGGGCATAAGTAAATACAATGCTTTACCAGAGGTAACTAACATACCCAA
AGGAATGGTAGATACGGGCTTATTAGAAAGTGAAAGTGCTAAAATAGTAGAAGAAATGATTAATGAAATAAAAAATGAGG
AGAAAACAGTATCATTTGAGATTAAAGCAAGACTTAAAAAAGAAGAAGAATTTAAATGGTTTAGAATGACGTTATCTTCT
TATTACGAAGCATATACACGTGAATTATGTGCTGTTGGTTTTATTAAAAATGTCAATGATGAAATATTATATAGGAATGA
ATTAAAATTTAAGGCAGATATGGATGGATTAACTGAAATATACAATGCAATAGCTGGTAGACAACTTATAGAAGTATATT
TGAGGAAATTTAATGATTCATCAGTTAAAAATGCTATGTTTATTTTTGATATTGATAATTTTAAGGCAATAAATGATGAA
AAGGGGCATTATACTGGGGATTTGGTTTTAAAGGAATTTGCTAAGGTTTTAAAAAATACTTTTCATGATGATGATATTGT
TTTAAGGCTTGGTGGGGATGAATTTGTAGTTTTTATGAAAAAATTTATAAATGAATTTGAAATGGAAAATGCCTGCAATA
AGATATTTGAATTGCTAGAGGAAAATAAAAAATTTGATTTTGATATATCTGTAAGCGTTGGCATTGCTATAAGTAATAGA
ACTGATGCTAGATGTGTAAATTATTATAAGGTAGCTGATGATGCTTTATATAAGGTTAAAAAATGTGGAAAAAATTCATA
TTATTTTGAACATTTTTAA

Upstream 100 bases:

>100_bases
AAAAAAGAAGTATCGCTTAAAATAGTGAAATAAATTACACAAGATTATTATGATATGTGCTTTATATTAAATTTATAAAG
TTGATTTTAAGGGGAGAGCA

Downstream 100 bases:

>100_bases
ATATATGTTAATTATAGTATTAAGTTTAACTATTACAGCCTGTTATTCTAAAAAATATCCTAGCAATTATCCTCCCTTGA
TCATTGAATGTAATGGGGTG

Product: signaling protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 432; Mature: 431

Protein sequence:

>432_residues
MSKKNTEPISNFIGSYKQQIGYLDKMPVAVAIIKVEVNEIGEPSDFIFVYVNEALTKIENLSKEKLLGSSFYEVFKNGEK
KWLYEYWKTAYNGTNKEIYEYSKALNKFLSISCYQPSYGYCGCVLKDMSDKMILEAENTKKQKRIDIILKNSIDAIFDLD
LKTNTILNESVGISKYNALPEVTNIPKGMVDTGLLESESAKIVEEMINEIKNEEKTVSFEIKARLKKEEEFKWFRMTLSS
YYEAYTRELCAVGFIKNVNDEILYRNELKFKADMDGLTEIYNAIAGRQLIEVYLRKFNDSSVKNAMFIFDIDNFKAINDE
KGHYTGDLVLKEFAKVLKNTFHDDDIVLRLGGDEFVVFMKKFINEFEMENACNKIFELLEENKKFDFDISVSVGIAISNR
TDARCVNYYKVADDALYKVKKCGKNSYYFEHF

Sequences:

>Translated_432_residues
MSKKNTEPISNFIGSYKQQIGYLDKMPVAVAIIKVEVNEIGEPSDFIFVYVNEALTKIENLSKEKLLGSSFYEVFKNGEK
KWLYEYWKTAYNGTNKEIYEYSKALNKFLSISCYQPSYGYCGCVLKDMSDKMILEAENTKKQKRIDIILKNSIDAIFDLD
LKTNTILNESVGISKYNALPEVTNIPKGMVDTGLLESESAKIVEEMINEIKNEEKTVSFEIKARLKKEEEFKWFRMTLSS
YYEAYTRELCAVGFIKNVNDEILYRNELKFKADMDGLTEIYNAIAGRQLIEVYLRKFNDSSVKNAMFIFDIDNFKAINDE
KGHYTGDLVLKEFAKVLKNTFHDDDIVLRLGGDEFVVFMKKFINEFEMENACNKIFELLEENKKFDFDISVSVGIAISNR
TDARCVNYYKVADDALYKVKKCGKNSYYFEHF
>Mature_431_residues
SKKNTEPISNFIGSYKQQIGYLDKMPVAVAIIKVEVNEIGEPSDFIFVYVNEALTKIENLSKEKLLGSSFYEVFKNGEKK
WLYEYWKTAYNGTNKEIYEYSKALNKFLSISCYQPSYGYCGCVLKDMSDKMILEAENTKKQKRIDIILKNSIDAIFDLDL
KTNTILNESVGISKYNALPEVTNIPKGMVDTGLLESESAKIVEEMINEIKNEEKTVSFEIKARLKKEEEFKWFRMTLSSY
YEAYTRELCAVGFIKNVNDEILYRNELKFKADMDGLTEIYNAIAGRQLIEVYLRKFNDSSVKNAMFIFDIDNFKAINDEK
GHYTGDLVLKEFAKVLKNTFHDDDIVLRLGGDEFVVFMKKFINEFEMENACNKIFELLEENKKFDFDISVSVGIAISNRT
DARCVNYYKVADDALYKVKKCGKNSYYFEHF

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GGDEF domain [H]

Homologues:

Organism=Escherichia coli, GI1786584, Length=169, Percent_Identity=33.1360946745562, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI1788381, Length=182, Percent_Identity=26.3736263736264, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1787541, Length=178, Percent_Identity=26.9662921348315, Blast_Score=73, Evalue=4e-14,
Organism=Escherichia coli, GI145693134, Length=165, Percent_Identity=30.3030303030303, Blast_Score=72, Evalue=9e-14,
Organism=Escherichia coli, GI1787262, Length=143, Percent_Identity=29.3706293706294, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI1787816, Length=200, Percent_Identity=28, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI87082007, Length=211, Percent_Identity=27.4881516587678, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1788956, Length=160, Percent_Identity=31.875, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI1787802, Length=169, Percent_Identity=30.1775147928994, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1787056, Length=164, Percent_Identity=33.5365853658537, Blast_Score=62, Evalue=7e-11,
Organism=Escherichia coli, GI87081974, Length=155, Percent_Identity=31.6129032258064, Blast_Score=62, Evalue=1e-10,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR007894 [H]

Pfam domain/function: PF00990 GGDEF; PF05230 MASE2 [H]

EC number: NA

Molecular weight: Translated: 50094; Mature: 49963

Theoretical pI: Translated: 5.13; Mature: 5.13

Prosite motif: PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKKNTEPISNFIGSYKQQIGYLDKMPVAVAIIKVEVNEIGEPSDFIFVYVNEALTKIEN
CCCCCCCHHHHHHHHHHHHHCCCCCCCEEEEEEEEECCCCCCCCCEEEEEHHHHHHHHHH
LSKEKLLGSSFYEVFKNGEKKWLYEYWKTAYNGTNKEIYEYSKALNKFLSISCYQPSYGY
CCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHEEEECCCCCCC
CGCVLKDMSDKMILEAENTKKQKRIDIILKNSIDAIFDLDLKTNTILNESVGISKYNALP
HHHHHHCCCCCEEEECCCCCCHHHEEEEEECCCCEEEEECCCCCCEECCCCCCHHHCCCC
EVTNIPKGMVDTGLLESESAKIVEEMINEIKNEEKTVSFEIKARLKKEEEFKWFRMTLSS
CHHCCCCCHHHCCCCCCHHHHHHHHHHHHHCCCCCEEEEEEEEHHCCHHHHHHHHHHHHH
YYEAYTRELCAVGFIKNVNDEILYRNELKFKADMDGLTEIYNAIAGRQLIEVYLRKFNDS
HHHHHHHHHHHHHHHHCCCCCEEEECCCCEECCCCHHHHHHHHHHHHHHHHHHHHHCCCC
SVKNAMFIFDIDNFKAINDEKGHYTGDLVLKEFAKVLKNTFHDDDIVLRLGGDEFVVFMK
CCCCEEEEEECCCCEECCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHH
KFINEFEMENACNKIFELLEENKKFDFDISVSVGIAISNRTDARCVNYYKVADDALYKVK
HHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHH
KCGKNSYYFEHF
HCCCCCCEECCC
>Mature Secondary Structure 
SKKNTEPISNFIGSYKQQIGYLDKMPVAVAIIKVEVNEIGEPSDFIFVYVNEALTKIEN
CCCCCCHHHHHHHHHHHHHCCCCCCCEEEEEEEEECCCCCCCCCEEEEEHHHHHHHHHH
LSKEKLLGSSFYEVFKNGEKKWLYEYWKTAYNGTNKEIYEYSKALNKFLSISCYQPSYGY
CCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHEEEECCCCCCC
CGCVLKDMSDKMILEAENTKKQKRIDIILKNSIDAIFDLDLKTNTILNESVGISKYNALP
HHHHHHCCCCCEEEECCCCCCHHHEEEEEECCCCEEEEECCCCCCEECCCCCCHHHCCCC
EVTNIPKGMVDTGLLESESAKIVEEMINEIKNEEKTVSFEIKARLKKEEEFKWFRMTLSS
CHHCCCCCHHHCCCCCCHHHHHHHHHHHHHCCCCCEEEEEEEEHHCCHHHHHHHHHHHHH
YYEAYTRELCAVGFIKNVNDEILYRNELKFKADMDGLTEIYNAIAGRQLIEVYLRKFNDS
HHHHHHHHHHHHHHHHCCCCCEEEECCCCEECCCCHHHHHHHHHHHHHHHHHHHHHCCCC
SVKNAMFIFDIDNFKAINDEKGHYTGDLVLKEFAKVLKNTFHDDDIVLRLGGDEFVVFMK
CCCCEEEEEECCCCEECCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHH
KFINEFEMENACNKIFELLEENKKFDFDISVSVGIAISNRTDARCVNYYKVADDALYKVK
HHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHH
KCGKNSYYFEHF
HCCCCCCEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]