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The map label for this gene is glcK [H]

Identifier: 187932724

GI number: 187932724

Start: 3577173

End: 3578126

Strand: Reverse

Name: glcK [H]

Synonym: CLL_A3397

Alternate gene names: 187932724

Gene position: 3578126-3577173 (Counterclockwise)

Preceding gene: 187935253

Following gene: 187935473

Centisome position: 94.15

GC content: 33.54

Gene sequence:

>954_bases
ATGCAAAAATTTGTAGTAGGGGTTGACTTAGGAGGAACTAAGATAAGTACAGCTTTATCAAATTTAAATGGTGAAGTTAT
TAGCCAAACAACAGTTCCGACTAATGCACATGAGGGAGAAATTCCAGTATTAAATAGAATAATAGACTCGGTAGATAAGG
TAATAAAAGATGGTGGAGTTACTTATAAAGATATAAAAGCAATAGGTATTGGTTCTCCAGGACCACTTGATGCAGAAAAG
GGAGTAATAATATACACACCTAATCTTCCATTTAAAAACTTTAATTTAGTGGATCCACTAAATAAGAAGTTTGAAGTACC
TGTTTTCTTAGATAATGATGCAAACGTTGCGACTATTGGTGAGTTTATGTTTGGAGCAGGAAGAGGTGCTAAAAACGTAT
TATTCTTTACAGTAAGTACAGGCGTAGGCGGTGGAGCTATATTAGATGGAAAAATATATAGAGGTCATACATCAAATGCA
TTAGAAATAGGTCATATGACTGTAGCACCTGATGGTCCAAGATGTAATTGTGGAAATATTGGTTGTGTAGAAGCAACTTC
ATCAGGAACAGCTATAGGTAAAAGAGGTAAAGAAGCTATAGGAAGTAAAGTTGAAACATCATTAAGAAAATATGATGATA
TAACTTCATATGAAGTATTTGTAGAAGCAGCAGCTGGAGATCCAGTATGTAAAGATATAATAGATAATGCATTAAATTAT
TTAGGAATAGCTGTTGCAAATGCAGTATCAATTTTTGATCCAGAAGTAATAATAATTGGTGGAGGCGTTTCAAAAGCTGG
AAATATTGTATTTGATACAGTAAGAAAAGTTGTAGATAAGAGATGTTTTAAATCAATGGCTGAATCAGTTAAAATTGTAC
CAGCAGGACTTGGAACAGATGCAGGTGTTGTAGGAGCAGTAGCTTTAGCATTACTTGAAACTTCAGAAAAATAA

Upstream 100 bases:

>100_bases
ACATTCCTTTACACTAAATATTATAGTATAATGTAAATATATTAGAACCGTTACCGGTGAGAAAAATTAACAATTAGTAT
TCAGTATGGAGGATAAATTT

Downstream 100 bases:

>100_bases
TTTAAATAAGATTTTTTATAAAACCATTTAATTGTAATATATATTGCAGTTAAGTGGTTTTTATTTATGTAATAGACTAT
GTTTTAGTAGAGTGTTGATA

Product: glucokinase

Products: NA

Alternate protein names: Glucose kinase [H]

Number of amino acids: Translated: 317; Mature: 317

Protein sequence:

>317_residues
MQKFVVGVDLGGTKISTALSNLNGEVISQTTVPTNAHEGEIPVLNRIIDSVDKVIKDGGVTYKDIKAIGIGSPGPLDAEK
GVIIYTPNLPFKNFNLVDPLNKKFEVPVFLDNDANVATIGEFMFGAGRGAKNVLFFTVSTGVGGGAILDGKIYRGHTSNA
LEIGHMTVAPDGPRCNCGNIGCVEATSSGTAIGKRGKEAIGSKVETSLRKYDDITSYEVFVEAAAGDPVCKDIIDNALNY
LGIAVANAVSIFDPEVIIIGGGVSKAGNIVFDTVRKVVDKRCFKSMAESVKIVPAGLGTDAGVVGAVALALLETSEK

Sequences:

>Translated_317_residues
MQKFVVGVDLGGTKISTALSNLNGEVISQTTVPTNAHEGEIPVLNRIIDSVDKVIKDGGVTYKDIKAIGIGSPGPLDAEK
GVIIYTPNLPFKNFNLVDPLNKKFEVPVFLDNDANVATIGEFMFGAGRGAKNVLFFTVSTGVGGGAILDGKIYRGHTSNA
LEIGHMTVAPDGPRCNCGNIGCVEATSSGTAIGKRGKEAIGSKVETSLRKYDDITSYEVFVEAAAGDPVCKDIIDNALNY
LGIAVANAVSIFDPEVIIIGGGVSKAGNIVFDTVRKVVDKRCFKSMAESVKIVPAGLGTDAGVVGAVALALLETSEK
>Mature_317_residues
MQKFVVGVDLGGTKISTALSNLNGEVISQTTVPTNAHEGEIPVLNRIIDSVDKVIKDGGVTYKDIKAIGIGSPGPLDAEK
GVIIYTPNLPFKNFNLVDPLNKKFEVPVFLDNDANVATIGEFMFGAGRGAKNVLFFTVSTGVGGGAILDGKIYRGHTSNA
LEIGHMTVAPDGPRCNCGNIGCVEATSSGTAIGKRGKEAIGSKVETSLRKYDDITSYEVFVEAAAGDPVCKDIIDNALNY
LGIAVANAVSIFDPEVIIIGGGVSKAGNIVFDTVRKVVDKRCFKSMAESVKIVPAGLGTDAGVVGAVALALLETSEK

Specific function: Acts As A Repressor Of The Nagebacd Operon And Acts Both As An Activator And A Repressor For The Transcription Of The Glmsu Operon. [C]

COG id: COG1940

COG function: function code KG; Transcriptional regulator/sugar kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ROK (nagC/xylR) family [H]

Homologues:

Organism=Homo sapiens, GI298566315, Length=281, Percent_Identity=29.1814946619217, Blast_Score=118, Evalue=6e-27,
Organism=Homo sapiens, GI298566325, Length=281, Percent_Identity=29.1814946619217, Blast_Score=118, Evalue=7e-27,
Organism=Homo sapiens, GI190014632, Length=281, Percent_Identity=29.1814946619217, Blast_Score=118, Evalue=8e-27,
Organism=Homo sapiens, GI4885285, Length=281, Percent_Identity=29.1814946619217, Blast_Score=117, Evalue=1e-26,
Organism=Escherichia coli, GI1786891, Length=304, Percent_Identity=26.6447368421053, Blast_Score=148, Evalue=6e-37,
Organism=Escherichia coli, GI1787878, Length=297, Percent_Identity=28.2828282828283, Blast_Score=140, Evalue=8e-35,
Organism=Escherichia coli, GI87081733, Length=321, Percent_Identity=26.791277258567, Blast_Score=96, Evalue=4e-21,
Organism=Escherichia coli, GI1787363, Length=316, Percent_Identity=25.9493670886076, Blast_Score=95, Evalue=6e-21,
Organism=Escherichia coli, GI1790522, Length=319, Percent_Identity=26.0188087774295, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI87082127, Length=235, Percent_Identity=22.1276595744681, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI87082230, Length=263, Percent_Identity=28.8973384030418, Blast_Score=75, Evalue=8e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000600
- InterPro:   IPR004654 [H]

Pfam domain/function: PF00480 ROK [H]

EC number: =2.7.1.2 [H]

Molecular weight: Translated: 33004; Mature: 33004

Theoretical pI: Translated: 5.20; Mature: 5.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQKFVVGVDLGGTKISTALSNLNGEVISQTTVPTNAHEGEIPVLNRIIDSVDKVIKDGGV
CCEEEEEEECCCCHHHHHHHHCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHCCCC
TYKDIKAIGIGSPGPLDAEKGVIIYTPNLPFKNFNLVDPLNKKFEVPVFLDNDANVATIG
EEEHEEEEECCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCEEEEEEECCCCCEEEHH
EFMFGAGRGAKNVLFFTVSTGVGGGAILDGKIYRGHTSNALEIGHMTVAPDGPRCNCGNI
HHHHCCCCCCCEEEEEEEECCCCCCEEECCEEEECCCCCEEEECEEEECCCCCCCCCCCE
GCVEATSSGTAIGKRGKEAIGSKVETSLRKYDDITSYEVFVEAAAGDPVCKDIIDNALNY
EEEEECCCCCHHHCCCHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCHHHHHHHHHHHHH
LGIAVANAVSIFDPEVIIIGGGVSKAGNIVFDTVRKVVDKRCFKSMAESVKIVPAGLGTD
HHHHHHHHHHCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHCEEEEECCCCCC
AGVVGAVALALLETSEK
CHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MQKFVVGVDLGGTKISTALSNLNGEVISQTTVPTNAHEGEIPVLNRIIDSVDKVIKDGGV
CCEEEEEEECCCCHHHHHHHHCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHCCCC
TYKDIKAIGIGSPGPLDAEKGVIIYTPNLPFKNFNLVDPLNKKFEVPVFLDNDANVATIG
EEEHEEEEECCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCEEEEEEECCCCCEEEHH
EFMFGAGRGAKNVLFFTVSTGVGGGAILDGKIYRGHTSNALEIGHMTVAPDGPRCNCGNI
HHHHCCCCCCCEEEEEEEECCCCCCEEECCEEEECCCCCEEEECEEEECCCCCCCCCCCE
GCVEATSSGTAIGKRGKEAIGSKVETSLRKYDDITSYEVFVEAAAGDPVCKDIIDNALNY
EEEEECCCCCHHHCCCHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCHHHHHHHHHHHHH
LGIAVANAVSIFDPEVIIIGGGVSKAGNIVFDTVRKVVDKRCFKSMAESVKIVPAGLGTD
HHHHHHHHHHCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHCEEEEECCCCCC
AGVVGAVALALLETSEK
CHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]