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The map label for this gene is ytfL [C]

Identifier: 187932353

GI number: 187932353

Start: 3632803

End: 3634122

Strand: Reverse

Name: ytfL [C]

Synonym: CLL_A3436

Alternate gene names: 187932353

Gene position: 3634122-3632803 (Counterclockwise)

Preceding gene: 187932928

Following gene: 187934909

Centisome position: 95.63

GC content: 27.35

Gene sequence:

>1320_bases
ATGCAACCAGAGGCTGGGTCTGTGAATATAACTTCACAAATAATTTTAATAGTCATTTTAACATTAGTTAATGCATTTTT
TGCCTCAGCAGAAATGGCCATAGTGTCATTAAATAAAAATAAAATAAAACTTCTTGCAGAAGAAGGAAATAAGAAGGCAA
TAACGTTATTAAAACTTATGGAAGAGCCAACTAAGTTTCTATCTACTATACAAGTTGGTATAACTCTTGCAGGATTTTTT
AATAGTGCTTCTGCTGCTACTGGAATATCACAAGATTTAGCACGTTATCTAAGTGGACTTAATGTACCATATAGCAATAA
AATAGCATTAATAATAGTAACTGTTATTATATCTTATATAACATTAGTATTTGGAGAGTTATTTCCAAAGAGAATAGCAC
TTAAGAAATCTGAGACTATTGCAATGTTTTCTGTAAGACCTATATTATATGTATCTAAAATAACTGCACCATTTATAAAA
CTTCTTTCAGCATCAACAAATATATTAGTTAGTTTAGCGGGGTTAGATAAAGAAGGATTAGATGAAAAAGTGTCCAAAGA
AGAAATAAAGTCGTTAGTAGAAGTAGGGCAAGAACATGGTGTTATAAATGAAACTGAAAAAGAAATGATAAACAGTATAT
TTGAGTTTGATGATAAGCTAGCAGATGAAGTAATGACACCAAGAACAGAAGTGTACTTAATTAATATAGATAAGCCTTTG
GAAGAATATTTAGATGAATTATTAGAAGAAAAATATTCTAGGGTACCTGTATATGAAGAGGATATTGACAATATTATAGG
GATATTATATATGAAAGATTTTATACTTGAAGCACGTAAACATGAATTTGAAAATGTGAATATAAGAGAAATATTACATT
CACCATATTTTGTACCTGAAACTAAAAATATTGATGATTTATTTAATGAACTTAAAAGTTATAAAAAGCATATGGCAATA
CTTATAGATGAATATGGAGGTTTTTCAGGAATAGTTACAATAGAAGATTTAGTAGAAGAAGTTATGGGAAATATAGATGA
TGAATATGATGAAGAAGAATGTTTTATACAAAAGATAGATAGCAGCACATTTATAGTTAATGGGTTAATGCCCATAGATG
ATTTAAATGATTATCTTCATATTCAGCTAGTTTCTGATGAGTGTGATACTATAAGTGGATTTTTAATTAATATTATGGGA
AAAATACCAAATAATATAGAGGAAAAAGTAATTGAATACGAGAATATAATATTTAAAATAGAATCCATAAAAGAAAAGAG
AATAGAAAAAATAAAGATATGTATACAAAATGATAAGTAG

Upstream 100 bases:

>100_bases
TTAAAATATATAATTAGGAACAATATAAGTATATATAAATATTTTATATATGGCATTATCATAATTTTTTTATATTAGAT
AAATTGGGGAGGAAATAATA

Downstream 100 bases:

>100_bases
AAACTATTTAAAAATGAATATTAATTTATAGTCAGGGGGATTGGGAAATGGGGAATTTTAATGAAACTAAAATGGATGGT
GTATACGTTATAGAACCTGG

Product: CBS/transporter domain protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 439; Mature: 439

Protein sequence:

>439_residues
MQPEAGSVNITSQIILIVILTLVNAFFASAEMAIVSLNKNKIKLLAEEGNKKAITLLKLMEEPTKFLSTIQVGITLAGFF
NSASAATGISQDLARYLSGLNVPYSNKIALIIVTVIISYITLVFGELFPKRIALKKSETIAMFSVRPILYVSKITAPFIK
LLSASTNILVSLAGLDKEGLDEKVSKEEIKSLVEVGQEHGVINETEKEMINSIFEFDDKLADEVMTPRTEVYLINIDKPL
EEYLDELLEEKYSRVPVYEEDIDNIIGILYMKDFILEARKHEFENVNIREILHSPYFVPETKNIDDLFNELKSYKKHMAI
LIDEYGGFSGIVTIEDLVEEVMGNIDDEYDEEECFIQKIDSSTFIVNGLMPIDDLNDYLHIQLVSDECDTISGFLINIMG
KIPNNIEEKVIEYENIIFKIESIKEKRIEKIKICIQNDK

Sequences:

>Translated_439_residues
MQPEAGSVNITSQIILIVILTLVNAFFASAEMAIVSLNKNKIKLLAEEGNKKAITLLKLMEEPTKFLSTIQVGITLAGFF
NSASAATGISQDLARYLSGLNVPYSNKIALIIVTVIISYITLVFGELFPKRIALKKSETIAMFSVRPILYVSKITAPFIK
LLSASTNILVSLAGLDKEGLDEKVSKEEIKSLVEVGQEHGVINETEKEMINSIFEFDDKLADEVMTPRTEVYLINIDKPL
EEYLDELLEEKYSRVPVYEEDIDNIIGILYMKDFILEARKHEFENVNIREILHSPYFVPETKNIDDLFNELKSYKKHMAI
LIDEYGGFSGIVTIEDLVEEVMGNIDDEYDEEECFIQKIDSSTFIVNGLMPIDDLNDYLHIQLVSDECDTISGFLINIMG
KIPNNIEEKVIEYENIIFKIESIKEKRIEKIKICIQNDK
>Mature_439_residues
MQPEAGSVNITSQIILIVILTLVNAFFASAEMAIVSLNKNKIKLLAEEGNKKAITLLKLMEEPTKFLSTIQVGITLAGFF
NSASAATGISQDLARYLSGLNVPYSNKIALIIVTVIISYITLVFGELFPKRIALKKSETIAMFSVRPILYVSKITAPFIK
LLSASTNILVSLAGLDKEGLDEKVSKEEIKSLVEVGQEHGVINETEKEMINSIFEFDDKLADEVMTPRTEVYLINIDKPL
EEYLDELLEEKYSRVPVYEEDIDNIIGILYMKDFILEARKHEFENVNIREILHSPYFVPETKNIDDLFNELKSYKKHMAI
LIDEYGGFSGIVTIEDLVEEVMGNIDDEYDEEECFIQKIDSSTFIVNGLMPIDDLNDYLHIQLVSDECDTISGFLINIMG
KIPNNIEEKVIEYENIIFKIESIKEKRIEKIKICIQNDK

Specific function: Unknown

COG id: COG1253

COG function: function code R; Hemolysins and related proteins containing CBS domains

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

Organism=Homo sapiens, GI310128564, Length=386, Percent_Identity=30.8290155440415, Blast_Score=207, Evalue=2e-53,
Organism=Homo sapiens, GI40068055, Length=349, Percent_Identity=22.9226361031519, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI40068053, Length=349, Percent_Identity=22.9226361031519, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI94681046, Length=266, Percent_Identity=24.0601503759398, Blast_Score=69, Evalue=8e-12,
Organism=Escherichia coli, GI1790664, Length=426, Percent_Identity=26.056338028169, Blast_Score=174, Evalue=1e-44,
Organism=Escherichia coli, GI145693175, Length=417, Percent_Identity=23.9808153477218, Blast_Score=152, Evalue=6e-38,
Organism=Escherichia coli, GI1786879, Length=258, Percent_Identity=30.6201550387597, Blast_Score=137, Evalue=2e-33,
Organism=Escherichia coli, GI87082033, Length=344, Percent_Identity=25, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI1788119, Length=237, Percent_Identity=25.3164556962025, Blast_Score=80, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17554630, Length=256, Percent_Identity=25.390625, Blast_Score=68, Evalue=8e-12,
Organism=Saccharomyces cerevisiae, GI6324512, Length=360, Percent_Identity=21.6666666666667, Blast_Score=68, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR000644
- InterPro:   IPR002550
- InterPro:   IPR005170 [H]

Pfam domain/function: PF00571 CBS; PF03471 CorC_HlyC; PF01595 DUF21 [H]

EC number: NA

Molecular weight: Translated: 49736; Mature: 49736

Theoretical pI: Translated: 4.33; Mature: 4.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQPEAGSVNITSQIILIVILTLVNAFFASAEMAIVSLNKNKIKLLAEEGNKKAITLLKLM
CCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCEEEEEEECCCCHHHHHHHHH
EEPTKFLSTIQVGITLAGFFNSASAATGISQDLARYLSGLNVPYSNKIALIIVTVIISYI
HHHHHHHHHHHHHHHHHHHHCCCHHHCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHH
TLVFGELFPKRIALKKSETIAMFSVRPILYVSKITAPFIKLLSASTNILVSLAGLDKEGL
HHHHHHHHHHHHHHCCCCEEEEEEECHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCC
DEKVSKEEIKSLVEVGQEHGVINETEKEMINSIFEFDDKLADEVMTPRTEVYLINIDKPL
HHHCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCHHH
EEYLDELLEEKYSRVPVYEEDIDNIIGILYMKDFILEARKHEFENVNIREILHSPYFVPE
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCCCC
TKNIDDLFNELKSYKKHMAILIDEYGGFSGIVTIEDLVEEVMGNIDDEYDEEECFIQKID
CCCHHHHHHHHHHHHHHHEEEEECCCCCCCEEEHHHHHHHHHCCCCCCCCHHHHHHHHCC
SSTFIVNGLMPIDDLNDYLHIQLVSDECDTISGFLINIMGKIPNNIEEKVIEYENIIFKI
CCEEEEECCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
ESIKEKRIEKIKICIQNDK
HHHHHHHHHHEEHEEECCC
>Mature Secondary Structure
MQPEAGSVNITSQIILIVILTLVNAFFASAEMAIVSLNKNKIKLLAEEGNKKAITLLKLM
CCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCEEEEEEECCCCHHHHHHHHH
EEPTKFLSTIQVGITLAGFFNSASAATGISQDLARYLSGLNVPYSNKIALIIVTVIISYI
HHHHHHHHHHHHHHHHHHHHCCCHHHCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHH
TLVFGELFPKRIALKKSETIAMFSVRPILYVSKITAPFIKLLSASTNILVSLAGLDKEGL
HHHHHHHHHHHHHHCCCCEEEEEEECHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCC
DEKVSKEEIKSLVEVGQEHGVINETEKEMINSIFEFDDKLADEVMTPRTEVYLINIDKPL
HHHCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCHHH
EEYLDELLEEKYSRVPVYEEDIDNIIGILYMKDFILEARKHEFENVNIREILHSPYFVPE
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCCCC
TKNIDDLFNELKSYKKHMAILIDEYGGFSGIVTIEDLVEEVMGNIDDEYDEEECFIQKID
CCCHHHHHHHHHHHHHHHEEEEECCCCCCCEEEHHHHHHHHHCCCCCCCCHHHHHHHHCC
SSTFIVNGLMPIDDLNDYLHIQLVSDECDTISGFLINIMGKIPNNIEEKVIEYENIIFKI
CCEEEEECCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
ESIKEKRIEKIKICIQNDK
HHHHHHHHHHEEHEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]