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The map label for this gene is alr [H]

Identifier: 187918034

GI number: 187918034

Start: 158961

End: 160061

Strand: Direct

Name: alr [H]

Synonym: BH0160

Alternate gene names: 187918034

Gene position: 158961-160061 (Clockwise)

Preceding gene: 187918033

Following gene: 187918035

Centisome position: 17.24

GC content: 27.52

Gene sequence:

>1101_bases
ATGACCAAACATAAAGAAATCATCATAAACCTTCAAAATCTAAACCATAATTTAACCTCAATAAAAAACCATATTCAAAA
AAGAGAATTAGTAGCCACACTCAAAAGCGATGCTTATGGACACGGACTTATTCAAACATTCAAATTCTTAAAAGAAAAAG
GGGTAAATTATTTTGGCCTCTTTTGGATAGATGATGCTTTAAAGCTTAAAAAAATAGATAAAAATGTAAACATACTGCTC
TACATTAACACAGACAAAAATGCAATAAAAAATTTAGTTAAGTTCAATATCACACCTTTTGTTGCTGACTCTCAATACTT
ATCACTAATAGAACAAGAATGTAGGAAACAAAATAAAAAAATTAAGGCTCACTTAAAAGTTGATGTCGGAATGAACAGAT
ATGGCATTAAAATAGAAGATGCTCTTAATCTAGCAATTCAAATTCAAAATTCAAAATCAATAGAATTTGAAGGAATTTGT
ACACATTTACCAACAACAGAAAATACAAAAATTACCCAAACACAAATCGAAAAATTTGTTTATTTCATAAATAAACTTAA
AAGCAAAAATATAAATCCAAAATTTATTCATGCTTCCAACTCAGAACATATAGCAAACTACAAAATAAGCGAAAAATTTA
ACATGGTAAGACCAGGACTTATTTTATATGGATATCATCCAAATCCAAACATCTCAAACAACAATTTACAACTTAAACCT
GTACTAAACTTATATTCAAAAATCATATTTCTTAAAAATATAAAAAAGGGAGAACAAATATCATACTCGGGGCTTTTTAC
CGCAAAAGAAGATATGCAAATCGGACTTATACCAGTTGGATATTTTGACGGAATTCCACAAAATACATCTAACAATTTTT
ATTGCATAATAAGAGATAGAAAATGCTTCATTAAAGGAAAAATCTGTATGAATATTTCAATCATAGAAATACCCAAAGAT
CTAAAAATCAACATAGGAGAAAAGGTAGAAATCATTTCTGAAAGATTAAGCTTAGATATACTTAGCAAGGAATCTGGCAT
AAGCAAATACGAAATACTTTGTTCCATTGGAAAACACGAGAAGAAAAAATATTTATATTAA

Upstream 100 bases:

>100_bases
AACTTACAGCATGCAATTCCAACTACAGTTCCAAAATTGAACAGAACAAAAATTTTTTAATGTCAATCTCACTAATGCAT
AATATACTATAATATACAAA

Downstream 100 bases:

>100_bases
ATTACCTAAAGAATTAAATTTTTGAAAATCAACTAAATTACCTTTACTATCATAAATCCATTTATAAACCGAAATACCCC
CAATATTATCCCTCAGTCTT

Product: alanine racemase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 366; Mature: 365

Protein sequence:

>366_residues
MTKHKEIIINLQNLNHNLTSIKNHIQKRELVATLKSDAYGHGLIQTFKFLKEKGVNYFGLFWIDDALKLKKIDKNVNILL
YINTDKNAIKNLVKFNITPFVADSQYLSLIEQECRKQNKKIKAHLKVDVGMNRYGIKIEDALNLAIQIQNSKSIEFEGIC
THLPTTENTKITQTQIEKFVYFINKLKSKNINPKFIHASNSEHIANYKISEKFNMVRPGLILYGYHPNPNISNNNLQLKP
VLNLYSKIIFLKNIKKGEQISYSGLFTAKEDMQIGLIPVGYFDGIPQNTSNNFYCIIRDRKCFIKGKICMNISIIEIPKD
LKINIGEKVEIISERLSLDILSKESGISKYEILCSIGKHEKKKYLY

Sequences:

>Translated_366_residues
MTKHKEIIINLQNLNHNLTSIKNHIQKRELVATLKSDAYGHGLIQTFKFLKEKGVNYFGLFWIDDALKLKKIDKNVNILL
YINTDKNAIKNLVKFNITPFVADSQYLSLIEQECRKQNKKIKAHLKVDVGMNRYGIKIEDALNLAIQIQNSKSIEFEGIC
THLPTTENTKITQTQIEKFVYFINKLKSKNINPKFIHASNSEHIANYKISEKFNMVRPGLILYGYHPNPNISNNNLQLKP
VLNLYSKIIFLKNIKKGEQISYSGLFTAKEDMQIGLIPVGYFDGIPQNTSNNFYCIIRDRKCFIKGKICMNISIIEIPKD
LKINIGEKVEIISERLSLDILSKESGISKYEILCSIGKHEKKKYLY
>Mature_365_residues
TKHKEIIINLQNLNHNLTSIKNHIQKRELVATLKSDAYGHGLIQTFKFLKEKGVNYFGLFWIDDALKLKKIDKNVNILLY
INTDKNAIKNLVKFNITPFVADSQYLSLIEQECRKQNKKIKAHLKVDVGMNRYGIKIEDALNLAIQIQNSKSIEFEGICT
HLPTTENTKITQTQIEKFVYFINKLKSKNINPKFIHASNSEHIANYKISEKFNMVRPGLILYGYHPNPNISNNNLQLKPV
LNLYSKIIFLKNIKKGEQISYSGLFTAKEDMQIGLIPVGYFDGIPQNTSNNFYCIIRDRKCFIKGKICMNISIIEIPKDL
KINIGEKVEIISERLSLDILSKESGISKYEILCSIGKHEKKKYLY

Specific function: Provides the D-alanine required for cell wall biosynthesis [H]

COG id: COG0787

COG function: function code M; Alanine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the alanine racemase family [H]

Homologues:

Organism=Escherichia coli, GI1790487, Length=363, Percent_Identity=25.6198347107438, Blast_Score=144, Evalue=1e-35,
Organism=Escherichia coli, GI1787439, Length=364, Percent_Identity=23.6263736263736, Blast_Score=134, Evalue=6e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000821
- InterPro:   IPR009006
- InterPro:   IPR011079
- InterPro:   IPR001608
- InterPro:   IPR020622 [H]

Pfam domain/function: PF00842 Ala_racemase_C; PF01168 Ala_racemase_N [H]

EC number: =5.1.1.1 [H]

Molecular weight: Translated: 42203; Mature: 42072

Theoretical pI: Translated: 10.02; Mature: 10.02

Prosite motif: PS00395 ALANINE_RACEMASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKHKEIIINLQNLNHNLTSIKNHIQKRELVATLKSDAYGHGLIQTFKFLKEKGVNYFGL
CCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCEEEE
FWIDDALKLKKIDKNVNILLYINTDKNAIKNLVKFNITPFVADSQYLSLIEQECRKQNKK
EEECCCHHHHCCCCCCEEEEEEECCHHHHHHHHHCCCCEEEECHHHHHHHHHHHHHCCCE
IKAHLKVDVGMNRYGIKIEDALNLAIQIQNSKSIEFEGICTHLPTTENTKITQTQIEKFV
EEEEEEEEECCCCCCEEEEHEEEEEEEEECCCCEEEEEEEECCCCCCCCEEHHHHHHHHH
YFINKLKSKNINPKFIHASNSEHIANYKISEKFNMVRPGLILYGYHPNPNISNNNLQLKP
HHHHHHHCCCCCCEEEECCCCCEEEEEEECCCCCCCCCCEEEEEECCCCCCCCCCEEEEH
VLNLYSKIIFLKNIKKGEQISYSGLFTAKEDMQIGLIPVGYFDGIPQNTSNNFYCIIRDR
HHHHHHHHHHEECCCCCCEEEECEEEEECCCCEEEEEEEHHHCCCCCCCCCCEEEEEECC
KCFIKGKICMNISIIEIPKDLKINIGEKVEIISERLSLDILSKESGISKYEILCSIGKHE
EEEEEEEEEEEEEEEECCCCCEECCCCHHHHHHHHHCEEEECCCCCCCEEEEEEECCCCC
KKKYLY
CCCCCC
>Mature Secondary Structure 
TKHKEIIINLQNLNHNLTSIKNHIQKRELVATLKSDAYGHGLIQTFKFLKEKGVNYFGL
CCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCEEEE
FWIDDALKLKKIDKNVNILLYINTDKNAIKNLVKFNITPFVADSQYLSLIEQECRKQNKK
EEECCCHHHHCCCCCCEEEEEEECCHHHHHHHHHCCCCEEEECHHHHHHHHHHHHHCCCE
IKAHLKVDVGMNRYGIKIEDALNLAIQIQNSKSIEFEGICTHLPTTENTKITQTQIEKFV
EEEEEEEEECCCCCCEEEEHEEEEEEEEECCCCEEEEEEEECCCCCCCCEEHHHHHHHHH
YFINKLKSKNINPKFIHASNSEHIANYKISEKFNMVRPGLILYGYHPNPNISNNNLQLKP
HHHHHHHCCCCCCEEEECCCCCEEEEEEECCCCCCCCCCEEEEEECCCCCCCCCCEEEEH
VLNLYSKIIFLKNIKKGEQISYSGLFTAKEDMQIGLIPVGYFDGIPQNTSNNFYCIIRDR
HHHHHHHHHHEECCCCCCEEEECEEEEECCCCEEEEEEEHHHCCCCCCCCCCEEEEEECC
KCFIKGKICMNISIIEIPKDLKINIGEKVEIISERLSLDILSKESGISKYEILCSIGKHE
EEEEEEEEEEEEEEEECCCCCEECCCCHHHHHHHHHCEEEECCCCCCCEEEEEEECCCCC
KKKYLY
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9403685 [H]