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The map label for this gene is asnC [H]

Identifier: 187917979

GI number: 187917979

Start: 98375

End: 99760

Strand: Direct

Name: asnC [H]

Synonym: BH0101

Alternate gene names: 187917979

Gene position: 98375-99760 (Clockwise)

Preceding gene: 187917964

Following gene: 187917980

Centisome position: 10.67

GC content: 32.18

Gene sequence:

>1386_bases
ATGTATAAGAGCATCAAAGAAATTTTAAGTAATCCTATACTAGATACTATGATCACAGTGAAAGGATGGATCAGAACAAA
ACGCAGTAATGGTAAAATCTCATTTGTAGAAATTAATGACGGGTCAAATATTAAAGGAATTCAAGCAGTCATTGATGAAG
AAGATCCTCAATTTGAAAAACAAGAATTTAAAAAGCTTACAACAGGTGCCAGCATATCCTTAACCGGAATCTTAATCTTA
AGTCCGGCAAAAGGACAAGCCTATGAAATTAAAACAACAAAGTTTAATGTAATTGGAGAAGCAGATCAAGAAACATATCT
TTTACAAAAGAAAAGGCACACCTTTGAATTCTTAAGAGAAATCCCTCATTTAAGAATTCGTACCAATACATTTGGAGCTG
TGGCCAGAATTAGAAACCAAATTTCTTATAAAATTCATGAATATTTCCAAAAAAATGGATTTTTTTATATCCATACCCCA
ATTATTACATCAAATGACGGAGAGGGGGCTGGTGAAATATTTCGTGTATCTACCCTAGATCTTAACAACATTGCAAAAGG
ACAAGAAATCGACTTTAAAAATGATTTTTTTGGCAAACAAGCATTCCTTACAGTAACTGGACAACTACACGGCGAAGCTT
ATGCAATGGCTTTATCAAAAATATATACATTCGGACCGACATTTAGAGCAGAAAATTCCAACACAACACGCCATGCCTCA
GAATTTTGGATGATTGAACCTGAAATGGCATTCTTTACGCTTGAAGATAATATCAATTTAGCAGAAGATTTCCTTAAGTA
TATTTTAAGAGAAACTTTAAATCATTGTGGCCAAGATATGGAATTTTTTGATAATTTCATTGAAAAAGGCCTAATAAAAA
AAATTGAAGATGTAATAAACTCTAACTTTGAAGTTATTACATATACCCAAGCCATTAAAAAACTTGAAAATGCAACAAAA
ACATTTGAAATAAAGCCTTACTGGGGAATGGATTTACAAACAGAACATGAAAGGTATTTAACAGAAGAAATCATCAAAAA
ACCTACTACGGTTATTGACTACCCAAAAGAATTTAAAGCATTTTACATGAAAATGAATGAAGACAACAAAACTGTTAAAG
GAATGGATATTCTAGTCCCACGCATCGGAGAAATAATTGGAGGCAGCGAGAGAGAAGATAATCTAGATAAGTTGAATAAA
AGAATAAAAGAACTAAATTTAGAAGTAGAAACTTTGAATTGGTACTTAGACTTAAGGAGATTTGGGTCGACTCCTCATTC
TGGATTTGGACTTGGACTTGAAAGATTAATTCAATATATAACAGGAATGGCTAATATTAGAGATGTCATCCCATTCCCAA
GAACCCCTAAAACTCTTTATTTCTAA

Upstream 100 bases:

>100_bases
TCAATAACAATGCTAATAAGTATTTATAGATTAACAAATTTTAAAACCGCAATAGGTTAAACTATAATTAGTATTAATAC
CAAGCATAGAAGGGGCAAAT

Downstream 100 bases:

>100_bases
TAAAGAGTTTTAGGAGGAAAATTTGCAAAGAAAAATCTTATGTAAAATATTATTAATGTCATCAACATTAATGTTATTCT
CAAATGAAAAACCAGAAAAT

Product: asparaginyl-tRNA synthetase

Products: NA

Alternate protein names: Asparagine--tRNA ligase; AsnRS [H]

Number of amino acids: Translated: 461; Mature: 461

Protein sequence:

>461_residues
MYKSIKEILSNPILDTMITVKGWIRTKRSNGKISFVEINDGSNIKGIQAVIDEEDPQFEKQEFKKLTTGASISLTGILIL
SPAKGQAYEIKTTKFNVIGEADQETYLLQKKRHTFEFLREIPHLRIRTNTFGAVARIRNQISYKIHEYFQKNGFFYIHTP
IITSNDGEGAGEIFRVSTLDLNNIAKGQEIDFKNDFFGKQAFLTVTGQLHGEAYAMALSKIYTFGPTFRAENSNTTRHAS
EFWMIEPEMAFFTLEDNINLAEDFLKYILRETLNHCGQDMEFFDNFIEKGLIKKIEDVINSNFEVITYTQAIKKLENATK
TFEIKPYWGMDLQTEHERYLTEEIIKKPTTVIDYPKEFKAFYMKMNEDNKTVKGMDILVPRIGEIIGGSEREDNLDKLNK
RIKELNLEVETLNWYLDLRRFGSTPHSGFGLGLERLIQYITGMANIRDVIPFPRTPKTLYF

Sequences:

>Translated_461_residues
MYKSIKEILSNPILDTMITVKGWIRTKRSNGKISFVEINDGSNIKGIQAVIDEEDPQFEKQEFKKLTTGASISLTGILIL
SPAKGQAYEIKTTKFNVIGEADQETYLLQKKRHTFEFLREIPHLRIRTNTFGAVARIRNQISYKIHEYFQKNGFFYIHTP
IITSNDGEGAGEIFRVSTLDLNNIAKGQEIDFKNDFFGKQAFLTVTGQLHGEAYAMALSKIYTFGPTFRAENSNTTRHAS
EFWMIEPEMAFFTLEDNINLAEDFLKYILRETLNHCGQDMEFFDNFIEKGLIKKIEDVINSNFEVITYTQAIKKLENATK
TFEIKPYWGMDLQTEHERYLTEEIIKKPTTVIDYPKEFKAFYMKMNEDNKTVKGMDILVPRIGEIIGGSEREDNLDKLNK
RIKELNLEVETLNWYLDLRRFGSTPHSGFGLGLERLIQYITGMANIRDVIPFPRTPKTLYF
>Mature_461_residues
MYKSIKEILSNPILDTMITVKGWIRTKRSNGKISFVEINDGSNIKGIQAVIDEEDPQFEKQEFKKLTTGASISLTGILIL
SPAKGQAYEIKTTKFNVIGEADQETYLLQKKRHTFEFLREIPHLRIRTNTFGAVARIRNQISYKIHEYFQKNGFFYIHTP
IITSNDGEGAGEIFRVSTLDLNNIAKGQEIDFKNDFFGKQAFLTVTGQLHGEAYAMALSKIYTFGPTFRAENSNTTRHAS
EFWMIEPEMAFFTLEDNINLAEDFLKYILRETLNHCGQDMEFFDNFIEKGLIKKIEDVINSNFEVITYTQAIKKLENATK
TFEIKPYWGMDLQTEHERYLTEEIIKKPTTVIDYPKEFKAFYMKMNEDNKTVKGMDILVPRIGEIIGGSEREDNLDKLNK
RIKELNLEVETLNWYLDLRRFGSTPHSGFGLGLERLIQYITGMANIRDVIPFPRTPKTLYF

Specific function: Unknown

COG id: COG0017

COG function: function code J; Aspartyl/asparaginyl-tRNA synthetases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI226491502, Length=446, Percent_Identity=43.4977578475336, Blast_Score=392, Evalue=1e-109,
Organism=Homo sapiens, GI4758762, Length=453, Percent_Identity=27.3730684326711, Blast_Score=175, Evalue=1e-43,
Organism=Homo sapiens, GI45439306, Length=356, Percent_Identity=28.6516853932584, Blast_Score=121, Evalue=1e-27,
Organism=Escherichia coli, GI1787161, Length=462, Percent_Identity=52.1645021645022, Blast_Score=517, Evalue=1e-148,
Organism=Escherichia coli, GI1790571, Length=480, Percent_Identity=22.7083333333333, Blast_Score=69, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17556372, Length=423, Percent_Identity=32.1513002364066, Blast_Score=189, Evalue=2e-48,
Organism=Caenorhabditis elegans, GI71984122, Length=455, Percent_Identity=27.032967032967, Blast_Score=173, Evalue=1e-43,
Organism=Caenorhabditis elegans, GI17551876, Length=342, Percent_Identity=29.2397660818713, Blast_Score=119, Evalue=3e-27,
Organism=Saccharomyces cerevisiae, GI6319872, Length=483, Percent_Identity=38.9233954451346, Blast_Score=315, Evalue=1e-86,
Organism=Saccharomyces cerevisiae, GI6321807, Length=454, Percent_Identity=28.8546255506608, Blast_Score=177, Evalue=2e-45,
Organism=Saccharomyces cerevisiae, GI6323011, Length=345, Percent_Identity=29.2753623188406, Blast_Score=117, Evalue=4e-27,
Organism=Drosophila melanogaster, GI19922416, Length=463, Percent_Identity=33.0453563714903, Blast_Score=253, Evalue=2e-67,
Organism=Drosophila melanogaster, GI19921528, Length=457, Percent_Identity=26.6958424507659, Blast_Score=160, Evalue=2e-39,
Organism=Drosophila melanogaster, GI17136276, Length=490, Percent_Identity=25.1020408163265, Blast_Score=117, Evalue=2e-26,

Paralogues:

None

Copy number: 80 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004364
- InterPro:   IPR018150
- InterPro:   IPR006195
- InterPro:   IPR004522
- InterPro:   IPR002312
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR004365 [H]

Pfam domain/function: PF00152 tRNA-synt_2; PF01336 tRNA_anti [H]

EC number: =6.1.1.22 [H]

Molecular weight: Translated: 53354; Mature: 53354

Theoretical pI: Translated: 6.62; Mature: 6.62

Prosite motif: PS50862 AA_TRNA_LIGASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYKSIKEILSNPILDTMITVKGWIRTKRSNGKISFVEINDGSNIKGIQAVIDEEDPQFEK
CCHHHHHHHCCCHHHHHHHHHHHEEEECCCCCEEEEEECCCCCCCHHHHEECCCCCCHHH
QEFKKLTTGASISLTGILILSPAKGQAYEIKTTKFNVIGEADQETYLLQKKRHTFEFLRE
HHHHHHHCCCCEEEEEEEEEECCCCCEEEEEEEEEEEEECCCCHHHHHHHHHHHHHHHHH
IPHLRIRTNTFGAVARIRNQISYKIHEYFQKNGFFYIHTPIITSNDGEGAGEIFRVSTLD
CCCEEEECCCHHHHHHHHHHHHHHHHHHHHHCCEEEEEECEEECCCCCCCCCEEEEEEEC
LNNIAKGQEIDFKNDFFGKQAFLTVTGQLHGEAYAMALSKIYTFGPTFRAENSNTTRHAS
CCCCCCCCCCCCCCCCCCCEEEEEEEEECCCHHHHHHHHHHHHCCCCEECCCCCCCCCCC
EFWMIEPEMAFFTLEDNINLAEDFLKYILRETLNHCGQDMEFFDNFIEKGLIKKIEDVIN
EEEEECCCEEEEEEECCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHC
SNFEVITYTQAIKKLENATKTFEIKPYWGMDLQTEHERYLTEEIIKKPTTVIDYPKEFKA
CCCEEEEHHHHHHHHHCCCCEEEECCCCCCCCCCHHHHHHHHHHHHCCCCEECCCHHHHH
FYMKMNEDNKTVKGMDILVPRIGEIIGGSEREDNLDKLNKRIKELNLEVETLNWYLDLRR
EEEEECCCCCEECCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCEEEEHHHHHHHHH
FGSTPHSGFGLGLERLIQYITGMANIRDVIPFPRTPKTLYF
HCCCCCCCCCHHHHHHHHHHHCHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure
MYKSIKEILSNPILDTMITVKGWIRTKRSNGKISFVEINDGSNIKGIQAVIDEEDPQFEK
CCHHHHHHHCCCHHHHHHHHHHHEEEECCCCCEEEEEECCCCCCCHHHHEECCCCCCHHH
QEFKKLTTGASISLTGILILSPAKGQAYEIKTTKFNVIGEADQETYLLQKKRHTFEFLRE
HHHHHHHCCCCEEEEEEEEEECCCCCEEEEEEEEEEEEECCCCHHHHHHHHHHHHHHHHH
IPHLRIRTNTFGAVARIRNQISYKIHEYFQKNGFFYIHTPIITSNDGEGAGEIFRVSTLD
CCCEEEECCCHHHHHHHHHHHHHHHHHHHHHCCEEEEEECEEECCCCCCCCCEEEEEEEC
LNNIAKGQEIDFKNDFFGKQAFLTVTGQLHGEAYAMALSKIYTFGPTFRAENSNTTRHAS
CCCCCCCCCCCCCCCCCCCEEEEEEEEECCCHHHHHHHHHHHHCCCCEECCCCCCCCCCC
EFWMIEPEMAFFTLEDNINLAEDFLKYILRETLNHCGQDMEFFDNFIEKGLIKKIEDVIN
EEEEECCCEEEEEEECCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHC
SNFEVITYTQAIKKLENATKTFEIKPYWGMDLQTEHERYLTEEIIKKPTTVIDYPKEFKA
CCCEEEEHHHHHHHHHCCCCEEEECCCCCCCCCCHHHHHHHHHHHHCCCCEECCCHHHHH
FYMKMNEDNKTVKGMDILVPRIGEIIGGSEREDNLDKLNKRIKELNLEVETLNWYLDLRR
EEEEECCCCCEECCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCEEEEHHHHHHHHH
FGSTPHSGFGLGLERLIQYITGMANIRDVIPFPRTPKTLYF
HCCCCCCCCCHHHHHHHHHHHCHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9403685 [H]