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The map label for this gene is yeaE [H]

Identifier: 187734144

GI number: 187734144

Start: 1848454

End: 1849308

Strand: Reverse

Name: yeaE [H]

Synonym: SbBS512_E2029

Alternate gene names: 187734144

Gene position: 1849308-1848454 (Counterclockwise)

Preceding gene: 187731802

Following gene: 187732955

Centisome position: 40.06

GC content: 49.94

Gene sequence:

>855_bases
ATGCAACAAAAAATGATTCAATTTAGTGGCGATGTCTCACTGCCAGCCATAGGGCAGGGAACATGGTATATGGGCGAAGA
TGCCAGTCAGCGCAAAACAGAAGTTGCTGCACTACGCGCGGGCATTGAGCTCGGTTTAACCCTCATTGATACCGCCGAAA
TGTATGCCGATGGCGGTGCCGAAAAGGTGGTTGGGGAAGCATTAACCGGTCTGCGTGATAACGTCTTTCTCATCTCTAAA
GTCTATCCGTGGAATGCTGGCAGGCAAAAAGCGATAAATGCATGCGAAGCCAGTTTATGCCGTCTCAATACTGATTATCT
CGATCTCTACTTATTACACTGGTCTGGCAGTTTCGCTTTTGAAGAGACTGTTGCAGCGATGGAAAAATTGATCGCCCAGA
GAAAAATCCGCCGCTGGGGCGTTTCTAACCTTGATTATGCTGATATGCAGGAACTCTGGCAGCTGCCGGGGGGAAATCAG
TGTGCCACTAATCAGGTGCTTTACCATCTCGGTTCACGAGGGATTGAGTACGATCTACTCCCCTGGTGCCAGCAACAGCA
GATGCCGGTGATGGCTTACAGTCCATTAGCCCAGGCCGGGCGGTTGCGCAATGGACTGTTAAAAAACGCGGTAGTCAACG
AAATTGCACATGCTCACAATATCAGCTCGGCACAAGTATTGTTGGCGAGGGTAATCAGCCATCAGGGTGTGATGGCGATT
CCAAAAGCGGCCACGATTGCCCATGTTCAACAGAATGCGGCTGTGCTTGAGGTCGAACTTTCGTCAGCGGAATTAACCAT
GCTGGATAAAGCGTATCCGGCACCAAAAGGAAAAACTGCGCTGGATATGGTGTGA

Upstream 100 bases:

>100_bases
ACAAATTCTGATAATGCATCTTTCCAGGGCATTTTGTGCATAAAAACAGGGCGTCACGCCTTGTTTTGCATTACGGTGGT
GCAATACCTGGGAGGAAACA

Downstream 100 bases:

>100_bases
TGTTGATACGTGCCGAATGCATCGCACCCGGCACACAACATTAACGCAAATTAACGTTTCGCAACGCGAATGGATTGCGC
CAGATGTGCAGGTTTCTCTT

Product: oxidoreductase, aldo/keto reductase family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 284; Mature: 284

Protein sequence:

>284_residues
MQQKMIQFSGDVSLPAIGQGTWYMGEDASQRKTEVAALRAGIELGLTLIDTAEMYADGGAEKVVGEALTGLRDNVFLISK
VYPWNAGRQKAINACEASLCRLNTDYLDLYLLHWSGSFAFEETVAAMEKLIAQRKIRRWGVSNLDYADMQELWQLPGGNQ
CATNQVLYHLGSRGIEYDLLPWCQQQQMPVMAYSPLAQAGRLRNGLLKNAVVNEIAHAHNISSAQVLLARVISHQGVMAI
PKAATIAHVQQNAAVLEVELSSAELTMLDKAYPAPKGKTALDMV

Sequences:

>Translated_284_residues
MQQKMIQFSGDVSLPAIGQGTWYMGEDASQRKTEVAALRAGIELGLTLIDTAEMYADGGAEKVVGEALTGLRDNVFLISK
VYPWNAGRQKAINACEASLCRLNTDYLDLYLLHWSGSFAFEETVAAMEKLIAQRKIRRWGVSNLDYADMQELWQLPGGNQ
CATNQVLYHLGSRGIEYDLLPWCQQQQMPVMAYSPLAQAGRLRNGLLKNAVVNEIAHAHNISSAQVLLARVISHQGVMAI
PKAATIAHVQQNAAVLEVELSSAELTMLDKAYPAPKGKTALDMV
>Mature_284_residues
MQQKMIQFSGDVSLPAIGQGTWYMGEDASQRKTEVAALRAGIELGLTLIDTAEMYADGGAEKVVGEALTGLRDNVFLISK
VYPWNAGRQKAINACEASLCRLNTDYLDLYLLHWSGSFAFEETVAAMEKLIAQRKIRRWGVSNLDYADMQELWQLPGGNQ
CATNQVLYHLGSRGIEYDLLPWCQQQQMPVMAYSPLAQAGRLRNGLLKNAVVNEIAHAHNISSAQVLLARVISHQGVMAI
PKAATIAHVQQNAAVLEVELSSAELTMLDKAYPAPKGKTALDMV

Specific function: Unknown

COG id: COG0656

COG function: function code R; Aldo/keto reductases, related to diketogulonate reductase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI223468663, Length=297, Percent_Identity=28.6195286195286, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI291291012, Length=265, Percent_Identity=29.811320754717, Blast_Score=105, Evalue=4e-23,
Organism=Homo sapiens, GI93277124, Length=305, Percent_Identity=26.8852459016393, Blast_Score=94, Evalue=1e-19,
Organism=Homo sapiens, GI24497577, Length=289, Percent_Identity=28.0276816608997, Blast_Score=90, Evalue=3e-18,
Organism=Homo sapiens, GI5174391, Length=289, Percent_Identity=28.0276816608997, Blast_Score=90, Evalue=3e-18,
Organism=Homo sapiens, GI4502049, Length=290, Percent_Identity=29.6551724137931, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI5174695, Length=301, Percent_Identity=25.5813953488372, Blast_Score=86, Evalue=4e-17,
Organism=Homo sapiens, GI310109922, Length=276, Percent_Identity=29.3478260869565, Blast_Score=83, Evalue=3e-16,
Organism=Homo sapiens, GI300116273, Length=287, Percent_Identity=26.4808362369338, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI300116271, Length=276, Percent_Identity=26.0869565217391, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI45446745, Length=296, Percent_Identity=27.7027027027027, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI4503285, Length=296, Percent_Identity=27.7027027027027, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI24497585, Length=290, Percent_Identity=27.5862068965517, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI310109920, Length=296, Percent_Identity=27.7027027027027, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI5453543, Length=296, Percent_Identity=27.3648648648649, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI223718702, Length=193, Percent_Identity=32.1243523316062, Blast_Score=65, Evalue=6e-11,
Organism=Escherichia coli, GI1788081, Length=284, Percent_Identity=96.4788732394366, Blast_Score=563, Evalue=1e-162,
Organism=Escherichia coli, GI1786400, Length=261, Percent_Identity=27.9693486590038, Blast_Score=95, Evalue=6e-21,
Organism=Escherichia coli, GI87081735, Length=200, Percent_Identity=31.5, Blast_Score=92, Evalue=5e-20,
Organism=Escherichia coli, GI87082198, Length=258, Percent_Identity=29.0697674418605, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1788070, Length=315, Percent_Identity=26.6666666666667, Blast_Score=89, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI17552492, Length=273, Percent_Identity=29.6703296703297, Blast_Score=109, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI17561298, Length=285, Percent_Identity=31.2280701754386, Blast_Score=102, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI71998625, Length=277, Percent_Identity=29.9638989169675, Blast_Score=99, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17564128, Length=307, Percent_Identity=26.7100977198697, Blast_Score=97, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17537077, Length=297, Percent_Identity=28.956228956229, Blast_Score=94, Evalue=7e-20,
Organism=Caenorhabditis elegans, GI17537075, Length=297, Percent_Identity=28.956228956229, Blast_Score=92, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17561300, Length=293, Percent_Identity=27.6450511945392, Blast_Score=85, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17538386, Length=290, Percent_Identity=28.6206896551724, Blast_Score=84, Evalue=8e-17,
Organism=Caenorhabditis elegans, GI17550248, Length=297, Percent_Identity=24.5791245791246, Blast_Score=73, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6324694, Length=293, Percent_Identity=26.962457337884, Blast_Score=84, Evalue=3e-17,
Organism=Saccharomyces cerevisiae, GI6320079, Length=287, Percent_Identity=25.7839721254355, Blast_Score=78, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6322556, Length=283, Percent_Identity=25.7950530035336, Blast_Score=75, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24644950, Length=312, Percent_Identity=31.0897435897436, Blast_Score=109, Evalue=2e-24,
Organism=Drosophila melanogaster, GI24663317, Length=299, Percent_Identity=22.4080267558528, Blast_Score=83, Evalue=2e-16,
Organism=Drosophila melanogaster, GI45553081, Length=290, Percent_Identity=23.7931034482759, Blast_Score=83, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24657054, Length=291, Percent_Identity=26.1168384879725, Blast_Score=82, Evalue=3e-16,
Organism=Drosophila melanogaster, GI20129731, Length=297, Percent_Identity=24.9158249158249, Blast_Score=75, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24662789, Length=309, Percent_Identity=25.5663430420712, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI281366140, Length=252, Percent_Identity=24.6031746031746, Blast_Score=73, Evalue=3e-13,
Organism=Drosophila melanogaster, GI21356425, Length=298, Percent_Identity=22.8187919463087, Blast_Score=72, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24662781, Length=288, Percent_Identity=26.0416666666667, Blast_Score=64, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: NA

Molecular weight: Translated: 31148; Mature: 31148

Theoretical pI: Translated: 6.24; Mature: 6.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQQKMIQFSGDVSLPAIGQGTWYMGEDASQRKTEVAALRAGIELGLTLIDTAEMYADGGA
CCCCEEEECCCCCCCCCCCCCEECCCCCHHHHHHHHHHHHHHHHCEEEEHHHHHHHCCCH
EKVVGEALTGLRDNVFLISKVYPWNAGRQKAINACEASLCRLNTDYLDLYLLHWSGSFAF
HHHHHHHHHCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCHH
EETVAAMEKLIAQRKIRRWGVSNLDYADMQELWQLPGGNQCATNQVLYHLGSRGIEYDLL
HHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCCCC
PWCQQQQMPVMAYSPLAQAGRLRNGLLKNAVVNEIAHAHNISSAQVLLARVISHQGVMAI
CCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCEEC
PKAATIAHVQQNAAVLEVELSSAELTMLDKAYPAPKGKTALDMV
CCHHHHHHHHCCCEEEEEEECCCCEEEHHHCCCCCCCCCCCCCC
>Mature Secondary Structure
MQQKMIQFSGDVSLPAIGQGTWYMGEDASQRKTEVAALRAGIELGLTLIDTAEMYADGGA
CCCCEEEECCCCCCCCCCCCCEECCCCCHHHHHHHHHHHHHHHHCEEEEHHHHHHHCCCH
EKVVGEALTGLRDNVFLISKVYPWNAGRQKAINACEASLCRLNTDYLDLYLLHWSGSFAF
HHHHHHHHHCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCHH
EETVAAMEKLIAQRKIRRWGVSNLDYADMQELWQLPGGNQCATNQVLYHLGSRGIEYDLL
HHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCCCC
PWCQQQQMPVMAYSPLAQAGRLRNGLLKNAVVNEIAHAHNISSAQVLLARVISHQGVMAI
CCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCEEC
PKAATIAHVQQNAAVLEVELSSAELTMLDKAYPAPKGKTALDMV
CCHHHHHHHHCCCEEEEEEECCCCEEEHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503 [H]