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The map label for this gene is tkt

Identifier: 187733803

GI number: 187733803

Start: 2625813

End: 2626979

Strand: Direct

Name: tkt

Synonym: SbBS512_E2831

Alternate gene names: 187733803

Gene position: 2625813-2626979 (Clockwise)

Preceding gene: 187733490

Following gene: 187733289

Centisome position: 56.89

GC content: 51.5

Gene sequence:

>1167_bases
ATGTCCCGAAAAGACCTTGCCAATGCGATTCGCGCACTCAGTATGGATGCGGTACAAAAAGCCAACTCTGGTCATCCCGG
CGCGCCGATGGGCATGGCTGATATTGCCGAAGTGCTGTGGAACGATTTTCTTAAACATAACCCTACCGACCCAACCTGGT
ATGATCGCGACCGCTTTATTCTTTCCAACGGTCACGCGTCGATGCTGCTCTACAGTTTGCTGCATCTGACCGGTTACGAC
CTGCCGCTGGAAGAGCTGAAGAACTTCCGTCAGTTGCATTCGAAAACCCCAGGCCACCCGGAGATTGGTTATACGCCCGG
TGTTGAAACCACCACCGGTCCACTTGGACAAGGTTTGGCGAACGCCGTCGGACTGGCGATAGCAGAGCGTACACTGGCGG
CGCAGTTTAATCAGCCGGATCATGAAATTGTCGATCACTTCACCTATGTGTTTATGGGCGACGGCTGCCTGATGGAAGGT
ATTTCCCACGAAGTCTGTTCGCTGGCGGGCACGCTAGGACTGGGCAAGCTGATTGGTTTTTACGATCACAACGGTATTTC
GATTGATGGAGAAACCGAAGGCTGGTTTACCGACGATACGGCAAAACGTTTTGAAGCCTATCACTGGCATGTGATCCATG
AAATCGACGGTCACGATCCGCAGGCGGTGAAGGAAGCGATCCTTGAAGCGCAAAGCGTGAAAGATAAGCCGTCGCTGATT
ATCTGCCGTACGGTGATTGGCTTTGGTTCGCCGAATAAAGCAGGTAAGGAAGAGGCGCACGGCGCACCACTGGGGGAAGA
AGAAGTGGCGCTGGCACGGCAAAAACTGGGCTGGCACCATCCGCCATTTGAGATCCCTAAAGAGATTTATCACGCCTGGG
ATGCCCGTGAAAAAGGCGAAAAAGCGCAGCAGAGCTGGAATGAGAAGTTTGCCGCCTATAAAAAGGCTCATCCGCAACTG
GCAGAAGAGTTTACCCGACGGATGAGCGGTGGTTTACCGAAGGACTGGGAGAAAACGACTCAGAAATATATCAATGAGTT
ACAGGCAAATCCGGCGAAAATCGCTACCCGTAAGGCTTCGCAAAATACGCTTAACGCTGATATGACTTTCCGTGTCAAAC
CGGAATCTCTAATTTTGACGATTTTCTTTTTAGGTTTAATTCCCTGA

Upstream 100 bases:

>100_bases
GTAGAAAAACTGTCTGAAGGCATTCGTCTGTTCGCCGTTGATCAACGCAAACTGGAAGATCTTCTTGCCGCCAAACTATA
AACCAGCCACGGAGTGTTAT

Downstream 100 bases:

>100_bases
GGGCGACGTAGCAGTAAATCCGACGGTGAATCACGCTGATATTCGCGGGTTGGATACCGCATTACAGAGGTCCGTCATAT
GAGCCTGCCACTTTCTTACG

Product: transketolase

Products: NA

Alternate protein names: TK 2 [H]

Number of amino acids: Translated: 388; Mature: 387

Protein sequence:

>388_residues
MSRKDLANAIRALSMDAVQKANSGHPGAPMGMADIAEVLWNDFLKHNPTDPTWYDRDRFILSNGHASMLLYSLLHLTGYD
LPLEELKNFRQLHSKTPGHPEIGYTPGVETTTGPLGQGLANAVGLAIAERTLAAQFNQPDHEIVDHFTYVFMGDGCLMEG
ISHEVCSLAGTLGLGKLIGFYDHNGISIDGETEGWFTDDTAKRFEAYHWHVIHEIDGHDPQAVKEAILEAQSVKDKPSLI
ICRTVIGFGSPNKAGKEEAHGAPLGEEEVALARQKLGWHHPPFEIPKEIYHAWDAREKGEKAQQSWNEKFAAYKKAHPQL
AEEFTRRMSGGLPKDWEKTTQKYINELQANPAKIATRKASQNTLNADMTFRVKPESLILTIFFLGLIP

Sequences:

>Translated_388_residues
MSRKDLANAIRALSMDAVQKANSGHPGAPMGMADIAEVLWNDFLKHNPTDPTWYDRDRFILSNGHASMLLYSLLHLTGYD
LPLEELKNFRQLHSKTPGHPEIGYTPGVETTTGPLGQGLANAVGLAIAERTLAAQFNQPDHEIVDHFTYVFMGDGCLMEG
ISHEVCSLAGTLGLGKLIGFYDHNGISIDGETEGWFTDDTAKRFEAYHWHVIHEIDGHDPQAVKEAILEAQSVKDKPSLI
ICRTVIGFGSPNKAGKEEAHGAPLGEEEVALARQKLGWHHPPFEIPKEIYHAWDAREKGEKAQQSWNEKFAAYKKAHPQL
AEEFTRRMSGGLPKDWEKTTQKYINELQANPAKIATRKASQNTLNADMTFRVKPESLILTIFFLGLIP
>Mature_387_residues
SRKDLANAIRALSMDAVQKANSGHPGAPMGMADIAEVLWNDFLKHNPTDPTWYDRDRFILSNGHASMLLYSLLHLTGYDL
PLEELKNFRQLHSKTPGHPEIGYTPGVETTTGPLGQGLANAVGLAIAERTLAAQFNQPDHEIVDHFTYVFMGDGCLMEGI
SHEVCSLAGTLGLGKLIGFYDHNGISIDGETEGWFTDDTAKRFEAYHWHVIHEIDGHDPQAVKEAILEAQSVKDKPSLII
CRTVIGFGSPNKAGKEEAHGAPLGEEEVALARQKLGWHHPPFEIPKEIYHAWDAREKGEKAQQSWNEKFAAYKKAHPQLA
EEFTRRMSGGLPKDWEKTTQKYINELQANPAKIATRKASQNTLNADMTFRVKPESLILTIFFLGLIP

Specific function: Unknown

COG id: COG0021

COG function: function code G; Transketolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transketolase family [H]

Homologues:

Organism=Homo sapiens, GI133778974, Length=266, Percent_Identity=33.4586466165414, Blast_Score=128, Evalue=1e-29,
Organism=Homo sapiens, GI205277463, Length=262, Percent_Identity=33.969465648855, Blast_Score=120, Evalue=2e-27,
Organism=Homo sapiens, GI4507521, Length=262, Percent_Identity=33.969465648855, Blast_Score=120, Evalue=2e-27,
Organism=Homo sapiens, GI225637459, Length=266, Percent_Identity=24.812030075188, Blast_Score=80, Evalue=4e-15,
Organism=Escherichia coli, GI1788808, Length=366, Percent_Identity=100, Blast_Score=768, Evalue=0.0,
Organism=Escherichia coli, GI48994911, Length=365, Percent_Identity=75.0684931506849, Blast_Score=606, Evalue=1e-175,
Organism=Caenorhabditis elegans, GI17539652, Length=270, Percent_Identity=29.6296296296296, Blast_Score=104, Evalue=8e-23,
Organism=Saccharomyces cerevisiae, GI6325331, Length=361, Percent_Identity=50.9695290858726, Blast_Score=359, Evalue=1e-100,
Organism=Saccharomyces cerevisiae, GI6319593, Length=363, Percent_Identity=44.9035812672176, Blast_Score=316, Evalue=5e-87,
Organism=Drosophila melanogaster, GI24666278, Length=294, Percent_Identity=32.6530612244898, Blast_Score=128, Evalue=7e-30,
Organism=Drosophila melanogaster, GI45551847, Length=274, Percent_Identity=33.5766423357664, Blast_Score=125, Evalue=5e-29,
Organism=Drosophila melanogaster, GI45550715, Length=274, Percent_Identity=33.5766423357664, Blast_Score=125, Evalue=5e-29,
Organism=Drosophila melanogaster, GI24645119, Length=234, Percent_Identity=33.7606837606838, Blast_Score=100, Evalue=2e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009014
- InterPro:   IPR015941
- InterPro:   IPR005475
- InterPro:   IPR005478
- InterPro:   IPR020826
- InterPro:   IPR005476
- InterPro:   IPR005474 [H]

Pfam domain/function: PF02779 Transket_pyr; PF02780 Transketolase_C; PF00456 Transketolase_N [H]

EC number: =2.2.1.1 [H]

Molecular weight: Translated: 43167; Mature: 43036

Theoretical pI: Translated: 6.29; Mature: 6.29

Prosite motif: PS00801 TRANSKETOLASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRKDLANAIRALSMDAVQKANSGHPGAPMGMADIAEVLWNDFLKHNPTDPTWYDRDRFI
CCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCEEE
LSNGHASMLLYSLLHLTGYDLPLEELKNFRQLHSKTPGHPEIGYTPGVETTTGPLGQGLA
EECCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHH
NAVGLAIAERTLAAQFNQPDHEIVDHFTYVFMGDGCLMEGISHEVCSLAGTLGLGKLIGF
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
YDHNGISIDGETEGWFTDDTAKRFEAYHWHVIHEIDGHDPQAVKEAILEAQSVKDKPSLI
CCCCCEEECCCCCCCCCCHHHHHHHHHHEEEEEECCCCCHHHHHHHHHHHHHCCCCCCEE
ICRTVIGFGSPNKAGKEEAHGAPLGEEEVALARQKLGWHHPPFEIPKEIYHAWDAREKGE
EEHHHHCCCCCCCCCCHHHCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHCHHHHHH
KAQQSWNEKFAAYKKAHPQLAEEFTRRMSGGLPKDWEKTTQKYINELQANPAKIATRKAS
HHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHCC
QNTLNADMTFRVKPESLILTIFFLGLIP
CCCCCCCEEEEECCHHHHHHHHHHHHCC
>Mature Secondary Structure 
SRKDLANAIRALSMDAVQKANSGHPGAPMGMADIAEVLWNDFLKHNPTDPTWYDRDRFI
CHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCEEE
LSNGHASMLLYSLLHLTGYDLPLEELKNFRQLHSKTPGHPEIGYTPGVETTTGPLGQGLA
EECCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHH
NAVGLAIAERTLAAQFNQPDHEIVDHFTYVFMGDGCLMEGISHEVCSLAGTLGLGKLIGF
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
YDHNGISIDGETEGWFTDDTAKRFEAYHWHVIHEIDGHDPQAVKEAILEAQSVKDKPSLI
CCCCCEEECCCCCCCCCCHHHHHHHHHHEEEEEECCCCCHHHHHHHHHHHHHCCCCCCEE
ICRTVIGFGSPNKAGKEEAHGAPLGEEEVALARQKLGWHHPPFEIPKEIYHAWDAREKGE
EEHHHHCCCCCCCCCCHHHCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHCHHHHHH
KAQQSWNEKFAAYKKAHPQLAEEFTRRMSGGLPKDWEKTTQKYINELQANPAKIATRKAS
HHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHCC
QNTLNADMTFRVKPESLILTIFFLGLIP
CCCCCCCEEEEECCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8396116; 9205837; 9278503 [H]