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The map label for this gene is hcaR [H]

Identifier: 187733336

GI number: 187733336

Start: 2716960

End: 2717358

Strand: Reverse

Name: hcaR [H]

Synonym: SbBS512_E2912

Alternate gene names: 187733336

Gene position: 2717358-2716960 (Counterclockwise)

Preceding gene: 187733543

Following gene: 187730033

Centisome position: 58.87

GC content: 49.87

Gene sequence:

>399_bases
GTGGTTGTGTTACCGGTTGATCACCCTTTAGCACATGAAAAAGAGATCACCGCCGCGCAACTGGATGGCGTGAATTTCGT
CAGTACCGATCCGGCGTATTCCGGTTCGCTTGCGCCGATCGTTAAAGCGTGGTTTGCGCAAGAAAACAGCCAGCCAAATA
TCGTCCAGGTGGCAACGAATATTCTGGTGACCATGAATCTGGTGGGCATGGGGCTGGGCGTCACTTTGATACCCGGTTAT
ATGAATAATTTTAATACCGGACAGGTTGTTTTTCGTCCCATTGCCGGAAATGTGCCTTCCATTGCTTTACTGATGGCGTG
GAAGAAAGGGGAGATGAAGCCGGCATTACGTGATTTCATCGCCATTGTGCAGGAACGTTTGGCAAGCGTAACGGCATAA

Upstream 100 bases:

>100_bases
TTATCTGAACATAAAACACTATCAATAATTTGGAGTCATTACCCGCCATCCTGTTTATAGCCCGGAGATTGATTATCTGG
AGCTTTTTGACGAACCATTA

Downstream 100 bases:

>100_bases
TTACGCATTATTTTTGCAACATGCGTCGCGGATCGCAGTTTTTTAGTGCTTGTGAACTGGCGTTACAGACATCGGGAAGC
AGGCTCGAATATTCTTATTT

Product: Hca operon transcriptional activator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 132; Mature: 132

Protein sequence:

>132_residues
MVVLPVDHPLAHEKEITAAQLDGVNFVSTDPAYSGSLAPIVKAWFAQENSQPNIVQVATNILVTMNLVGMGLGVTLIPGY
MNNFNTGQVVFRPIAGNVPSIALLMAWKKGEMKPALRDFIAIVQERLASVTA

Sequences:

>Translated_132_residues
MVVLPVDHPLAHEKEITAAQLDGVNFVSTDPAYSGSLAPIVKAWFAQENSQPNIVQVATNILVTMNLVGMGLGVTLIPGY
MNNFNTGQVVFRPIAGNVPSIALLMAWKKGEMKPALRDFIAIVQERLASVTA
>Mature_132_residues
MVVLPVDHPLAHEKEITAAQLDGVNFVSTDPAYSGSLAPIVKAWFAQENSQPNIVQVATNILVTMNLVGMGLGVTLIPGY
MNNFNTGQVVFRPIAGNVPSIALLMAWKKGEMKPALRDFIAIVQERLASVTA

Specific function: Transcriptional activator of the hca operon for 3- phenylpropionic acid catabolism [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788887, Length=132, Percent_Identity=98.4848484848485, Blast_Score=268, Evalue=9e-74,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 14172; Mature: 14172

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVVLPVDHPLAHEKEITAAQLDGVNFVSTDPAYSGSLAPIVKAWFAQENSQPNIVQVATN
CEEECCCCCCCCCCCCCHHHCCCCEEEECCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHH
ILVTMNLVGMGLGVTLIPGYMNNFNTGQVVFRPIAGNVPSIALLMAWKKGEMKPALRDFI
HHHHHHHHHHCCCEEECCCCCCCCCCCEEEEEECCCCCCCEEEEEEECCCCCCHHHHHHH
AIVQERLASVTA
HHHHHHHHHCCC
>Mature Secondary Structure
MVVLPVDHPLAHEKEITAAQLDGVNFVSTDPAYSGSLAPIVKAWFAQENSQPNIVQVATN
CEEECCCCCCCCCCCCCHHHCCCCEEEECCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHH
ILVTMNLVGMGLGVTLIPGYMNNFNTGQVVFRPIAGNVPSIALLMAWKKGEMKPALRDFI
HHHHHHHHHHCCCEEECCCCCCCCCCCEEEEEECCCCCCCEEEEEEECCCCCCHHHHHHH
AIVQERLASVTA
HHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503; 9603882 [H]