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The map label for this gene is iucA

Identifier: 187733037

GI number: 187733037

Start: 4330325

End: 4332049

Strand: Reverse

Name: iucA

Synonym: SbBS512_E4634

Alternate gene names: 187733037

Gene position: 4332049-4330325 (Counterclockwise)

Preceding gene: 187733253

Following gene: 187733667

Centisome position: 93.85

GC content: 54.26

Gene sequence:

>1725_bases
ATGACCCTGCCCTCTGAAAAACCAGCCACAGATGTGGCTGCGCAGTGCTTCCTGAATGCACTGATTCGTGAAACCACAGA
CTGGAAACTGACAGAATACCCGCCAGACGAATTGCTCATCCCGCTGGATGAGCAGAAATCGCTCCATTTCAGAGTGACTT
ATTTCTCCCCAACCCAGCATCACCGCTTTGCATTTCCTGCACGTCTGGTCACGGCATCAGGCAGTTATCCTGTCGACTTT
ACCACTCTCTCCCGGCTTATTATTGATAAGCTACGCCATCAACTGTTTCTGCCCGTTCCCCTCTGCGAAACTTTCCACCA
GCGCGTGCTGGAAAGCCATGTCCATACGCAACAGGCAATTGATGCCCGTCATGACTGGGCCGCTCTGCGTGAAAAAGCGT
TGAATTTTGGCGAGGCTGAGCAGGCGCTGCTGACAGGACACGCTTTCCACCCTGCGCCTAAGTCTCATGAACCGTTTAAC
CGGCGGGAGGCTGAACGCTACCTGCCTGATATGGCACCCCACTTCCCACTGCGGTGGTTTTCGGTGGATAAAACACAAAT
CGCCGGTGAAAGTTTGCATCTCAACCTTCAACAGCGGCTGACGCGATTTGCCGCAGAGAATGCGCCTCAGTTACTCAACG
AATTAAGTGACAACCAATGGCTGTTCCCGTTGCACCCGTGGCAGGGGGAATATCTTTTGCAGCAGGGGTGGTGCCAGGCA
CTTGTTGCTAAAGGGCTGATTAAAGACTTAGGTGAGGCCGGCACGTCGTGGCTGCCGACCACCTCTTCCCGTTCCCTCTA
CTGTGCCACCAGCCGCGATATGATCAAGTTCTCCCTGAGCGTACGGCTGACCAACTCCATCCGTACTCTGTCCGTGAAAG
AAGTGAAGCGTGGGATGCGCCTGGCACGCCTGGCTCAAACCGACGGCTGGCAGATGCTACAGGTCCGCTTCCCGACTTTC
CGGGTAATGCAGGAGGATGGCTGGGCCGGGCTGCTCGATCTTAACGGCAACATCATGCAGGAAAGTCTGTTTGCCCTGCG
TGAAAATCTGCTGGTGGATCAGCCGAAAAGCCAGACTAACGTACTGGTCTCCCTGACTCAGGCCGCACCTGATGGCGGTG
ATTCGCTGCTGGTTTCGGCGGTAAAACGCCTGAGCGATCGCCTCGGTATCACTGTGCAACAGGCCGCCCATGCATGGGTC
GATGCATACTGTCAGCAAGTGCTAAAGCCGCTGTTTACGGCTGAAGCGGATTACGGCCTGGTGCTGCTGGCGCATCAGCA
AAATATTCTTGTCCAGATGCTTGGGGATCTGCCGGTCGGATTTATTTACCGTGACTGTCAGGGCAGCGCTTTTATGCCTC
ACGCGACAGACTGGCTCGATTCTATTGGCGAGGCGCAGGCGGAAAATATTTTCACCCATGAGCAGTTGCTGCGCTATTTC
CCTTATTACCTGCTGGTTAACTCCACTTTTGCTGTGACCGCTGCGCTGGGGGCTGCCGGGCTGGACAGCGAATCGAATCT
GATGGCTCGTGTACGAGCATCGCTGGCTGAAGTGCGTGATCAGGTGACTCATAAAACCTGTCTCAACTACGTGCTGGAAA
GTCCGTACTGGAACGTAAAAGGTAACTTTTTCTGTTATCTGAACGATCATAACGAGAACACCATTGTTGATCCTTCGGTG
ATCTATTTCGATTTCGCTAACCCGCTGCAGGCTCAGGAGGTCTGA

Upstream 100 bases:

>100_bases
TTTGTAAAATTAATTTATCTGACAATAACATTTATTGTTGATAATGAGAATCATTATCGACATAATTGTTATTATTTTAC
TGTGTGGGAGCTGTTTGACT

Downstream 100 bases:

>100_bases
ATGTCTGAGGCAAACATTATTCACAGCAGATATGGACTGCGCTGTGAAAAACTCGACAAGCCCCTGAATCTTGGCTGGGG
ACTGGACAATAGCGCGGTGT

Product: aerobactin synthase subunit IucA

Products: ADP; phosphate; aerobactin

Alternate protein names: NA

Number of amino acids: Translated: 574; Mature: 573

Protein sequence:

>574_residues
MTLPSEKPATDVAAQCFLNALIRETTDWKLTEYPPDELLIPLDEQKSLHFRVTYFSPTQHHRFAFPARLVTASGSYPVDF
TTLSRLIIDKLRHQLFLPVPLCETFHQRVLESHVHTQQAIDARHDWAALREKALNFGEAEQALLTGHAFHPAPKSHEPFN
RREAERYLPDMAPHFPLRWFSVDKTQIAGESLHLNLQQRLTRFAAENAPQLLNELSDNQWLFPLHPWQGEYLLQQGWCQA
LVAKGLIKDLGEAGTSWLPTTSSRSLYCATSRDMIKFSLSVRLTNSIRTLSVKEVKRGMRLARLAQTDGWQMLQVRFPTF
RVMQEDGWAGLLDLNGNIMQESLFALRENLLVDQPKSQTNVLVSLTQAAPDGGDSLLVSAVKRLSDRLGITVQQAAHAWV
DAYCQQVLKPLFTAEADYGLVLLAHQQNILVQMLGDLPVGFIYRDCQGSAFMPHATDWLDSIGEAQAENIFTHEQLLRYF
PYYLLVNSTFAVTAALGAAGLDSESNLMARVRASLAEVRDQVTHKTCLNYVLESPYWNVKGNFFCYLNDHNENTIVDPSV
IYFDFANPLQAQEV

Sequences:

>Translated_574_residues
MTLPSEKPATDVAAQCFLNALIRETTDWKLTEYPPDELLIPLDEQKSLHFRVTYFSPTQHHRFAFPARLVTASGSYPVDF
TTLSRLIIDKLRHQLFLPVPLCETFHQRVLESHVHTQQAIDARHDWAALREKALNFGEAEQALLTGHAFHPAPKSHEPFN
RREAERYLPDMAPHFPLRWFSVDKTQIAGESLHLNLQQRLTRFAAENAPQLLNELSDNQWLFPLHPWQGEYLLQQGWCQA
LVAKGLIKDLGEAGTSWLPTTSSRSLYCATSRDMIKFSLSVRLTNSIRTLSVKEVKRGMRLARLAQTDGWQMLQVRFPTF
RVMQEDGWAGLLDLNGNIMQESLFALRENLLVDQPKSQTNVLVSLTQAAPDGGDSLLVSAVKRLSDRLGITVQQAAHAWV
DAYCQQVLKPLFTAEADYGLVLLAHQQNILVQMLGDLPVGFIYRDCQGSAFMPHATDWLDSIGEAQAENIFTHEQLLRYF
PYYLLVNSTFAVTAALGAAGLDSESNLMARVRASLAEVRDQVTHKTCLNYVLESPYWNVKGNFFCYLNDHNENTIVDPSV
IYFDFANPLQAQEV
>Mature_573_residues
TLPSEKPATDVAAQCFLNALIRETTDWKLTEYPPDELLIPLDEQKSLHFRVTYFSPTQHHRFAFPARLVTASGSYPVDFT
TLSRLIIDKLRHQLFLPVPLCETFHQRVLESHVHTQQAIDARHDWAALREKALNFGEAEQALLTGHAFHPAPKSHEPFNR
REAERYLPDMAPHFPLRWFSVDKTQIAGESLHLNLQQRLTRFAAENAPQLLNELSDNQWLFPLHPWQGEYLLQQGWCQAL
VAKGLIKDLGEAGTSWLPTTSSRSLYCATSRDMIKFSLSVRLTNSIRTLSVKEVKRGMRLARLAQTDGWQMLQVRFPTFR
VMQEDGWAGLLDLNGNIMQESLFALRENLLVDQPKSQTNVLVSLTQAAPDGGDSLLVSAVKRLSDRLGITVQQAAHAWVD
AYCQQVLKPLFTAEADYGLVLLAHQQNILVQMLGDLPVGFIYRDCQGSAFMPHATDWLDSIGEAQAENIFTHEQLLRYFP
YYLLVNSTFAVTAALGAAGLDSESNLMARVRASLAEVRDQVTHKTCLNYVLESPYWNVKGNFFCYLNDHNENTIVDPSVI
YFDFANPLQAQEV

Specific function: Unknown

COG id: COG4264

COG function: function code Q; Siderophore synthetase component

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iucA family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007310
- InterPro:   IPR022770 [H]

Pfam domain/function: PF06276 FhuF; PF04183 IucA_IucC [H]

EC number: 6.3.2.27

Molecular weight: Translated: 65049; Mature: 64918

Theoretical pI: Translated: 6.26; Mature: 6.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLPSEKPATDVAAQCFLNALIRETTDWKLTEYPPDELLIPLDEQKSLHFRVTYFSPTQH
CCCCCCCCHHHHHHHHHHHHHHHCCCCCEEECCCCCCEEEECCCCCCEEEEEEEECCCCC
HRFAFPARLVTASGSYPVDFTTLSRLIIDKLRHQLFLPVPLCETFHQRVLESHVHTQQAI
CCEECCEEEEEECCCCCCCHHHHHHHHHHHHHHHEECCCHHHHHHHHHHHHHHHHHHHHH
DARHDWAALREKALNFGEAEQALLTGHAFHPAPKSHEPFNRREAERYLPDMAPHFPLRWF
HHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCCEEEE
SVDKTQIAGESLHLNLQQRLTRFAAENAPQLLNELSDNQWLFPLHPWQGEYLLQQGWCQA
ECCHHHHCCCCEEEEHHHHHHHHHHCCHHHHHHHCCCCCEEEECCCCCCCHHHHHHHHHH
LVAKGLIKDLGEAGTSWLPTTSSRSLYCATSRDMIKFSLSVRLTNSIRTLSVKEVKRGMR
HHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCEEEEEEEEEEECCCCEEEHHHHHHHHH
LARLAQTDGWQMLQVRFPTFRVMQEDGWAGLLDLNGNIMQESLFALRENLLVDQPKSQTN
HHHHHCCCCCEEEEEECCEEEEEECCCCEEEEECCCCHHHHHHHHHHHHHHCCCCCCCCC
VLVSLTQAAPDGGDSLLVSAVKRLSDRLGITVQQAAHAWVDAYCQQVLKPLFTAEADYGL
EEEEEECCCCCCCHHHHHHHHHHHHHHHCEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCE
VLLAHQQNILVQMLGDLPVGFIYRDCQGSAFMPHATDWLDSIGEAQAENIFTHEQLLRYF
EEEEECHHHHHHHHHCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHC
PYYLLVNSTFAVTAALGAAGLDSESNLMARVRASLAEVRDQVTHKTCLNYVLESPYWNVK
CHHHHHCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECC
GNFFCYLNDHNENTIVDPSVIYFDFANPLQAQEV
CCEEEEEECCCCCEEECCEEEEEECCCCCCCCCC
>Mature Secondary Structure 
TLPSEKPATDVAAQCFLNALIRETTDWKLTEYPPDELLIPLDEQKSLHFRVTYFSPTQH
CCCCCCCHHHHHHHHHHHHHHHCCCCCEEECCCCCCEEEECCCCCCEEEEEEEECCCCC
HRFAFPARLVTASGSYPVDFTTLSRLIIDKLRHQLFLPVPLCETFHQRVLESHVHTQQAI
CCEECCEEEEEECCCCCCCHHHHHHHHHHHHHHHEECCCHHHHHHHHHHHHHHHHHHHHH
DARHDWAALREKALNFGEAEQALLTGHAFHPAPKSHEPFNRREAERYLPDMAPHFPLRWF
HHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCCEEEE
SVDKTQIAGESLHLNLQQRLTRFAAENAPQLLNELSDNQWLFPLHPWQGEYLLQQGWCQA
ECCHHHHCCCCEEEEHHHHHHHHHHCCHHHHHHHCCCCCEEEECCCCCCCHHHHHHHHHH
LVAKGLIKDLGEAGTSWLPTTSSRSLYCATSRDMIKFSLSVRLTNSIRTLSVKEVKRGMR
HHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCEEEEEEEEEEECCCCEEEHHHHHHHHH
LARLAQTDGWQMLQVRFPTFRVMQEDGWAGLLDLNGNIMQESLFALRENLLVDQPKSQTN
HHHHHCCCCCEEEEEECCEEEEEECCCCEEEEECCCCHHHHHHHHHHHHHHCCCCCCCCC
VLVSLTQAAPDGGDSLLVSAVKRLSDRLGITVQQAAHAWVDAYCQQVLKPLFTAEADYGL
EEEEEECCCCCCCHHHHHHHHHHHHHHHCEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCE
VLLAHQQNILVQMLGDLPVGFIYRDCQGSAFMPHATDWLDSIGEAQAENIFTHEQLLRYF
EEEEECHHHHHHHHHCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHC
PYYLLVNSTFAVTAALGAAGLDSESNLMARVRASLAEVRDQVTHKTCLNYVLESPYWNVK
CHHHHHCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECC
GNFFCYLNDHNENTIVDPSVIYFDFANPLQAQEV
CCEEEEEECCCCCEEECCEEEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; citrate; N6-acetyl-N6-hydroxylysine

Specific reaction: 4 ATP + citrate + N6-acetyl-N6-hydroxylysine = 4 ADP + 4 phosphate + aerobactin

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8003107 [H]