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The map label for this gene is kgtP [H]

Identifier: 187732714

GI number: 187732714

Start: 2755019

End: 2755453

Strand: Direct

Name: kgtP [H]

Synonym: SbBS512_E2950

Alternate gene names: 187732714

Gene position: 2755019-2755453 (Clockwise)

Preceding gene: 187730299

Following gene: 187730537

Centisome position: 59.68

GC content: 48.28

Gene sequence:

>435_bases
TTGTCTAATTCGTCAGATTCTGACCAGACGGTTCAGGCTGTACGCTTACAGATTGGTCGCCGTACCTCAATGTTATGTTT
CGGTTCGCTGGCAGCCATTTTTACCGTTCCTATTCTCTCAGCATTGCAAAACGTTTCCTCGCCTTATGCCGCTTTTGGTC
TGGTGATGTGTGCCCTGCTGATAGTGAGTTTTTATACATCAATCAGTGGAATACTGAAGGCTGAGATGTTCCCGGCACAG
GTTCGCGCATTAGGCGTTGGTCTGTCATATGCGGTCGCTAATGCTATATTTGGTGGTTCGGCGGAGTACGTAGCGTTGTC
GCTGAAATCAATAGGAATGGAAACTGCCTTCTTCTGGTATGTGACCTTGATGGCCGTGGTGGCGTTTCTGGTTTCTTTGA
TGCTACATCGCAAAGGGAAGGGGATGCGTCTTTAG

Upstream 100 bases:

>100_bases
TTCGGGAGGATAATTAGGGCAGCCTTTTCGCCTGCCGGGATTCACATTTTTCTGCATATCTGACACTTTGGTTCCCACTA
CTTATTTGGTGGACACCACT

Downstream 100 bases:

>100_bases
TGACGGGTCAGTTGCCAGACGGTATAGCCGGTGCTTGCACCGGCGACATCCCAGGCCAAATCCTTCCAGCTCCAGCCGCT
CCCTTCGGGGCGGCTATCCC

Product: alpha-ketoglutarate permease

Products: Proton [Cytoplasm]; 2-oxoglutarate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 144; Mature: 143

Protein sequence:

>144_residues
MSNSSDSDQTVQAVRLQIGRRTSMLCFGSLAAIFTVPILSALQNVSSPYAAFGLVMCALLIVSFYTSISGILKAEMFPAQ
VRALGVGLSYAVANAIFGGSAEYVALSLKSIGMETAFFWYVTLMAVVAFLVSLMLHRKGKGMRL

Sequences:

>Translated_144_residues
MSNSSDSDQTVQAVRLQIGRRTSMLCFGSLAAIFTVPILSALQNVSSPYAAFGLVMCALLIVSFYTSISGILKAEMFPAQ
VRALGVGLSYAVANAIFGGSAEYVALSLKSIGMETAFFWYVTLMAVVAFLVSLMLHRKGKGMRL
>Mature_143_residues
SNSSDSDQTVQAVRLQIGRRTSMLCFGSLAAIFTVPILSALQNVSSPYAAFGLVMCALLIVSFYTSISGILKAEMFPAQV
RALGVGLSYAVANAIFGGSAEYVALSLKSIGMETAFFWYVTLMAVVAFLVSLMLHRKGKGMRL

Specific function: Uptake of alpha-ketoglutarate across the boundary membrane with the concomitant import of a cation (symport system) [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family [H]

Homologues:

Organism=Escherichia coli, GI1788942, Length=134, Percent_Identity=95.5223880597015, Blast_Score=253, Evalue=4e-69,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004736
- InterPro:   IPR020846
- InterPro:   IPR016196
- InterPro:   IPR005828
- InterPro:   IPR005829 [H]

Pfam domain/function: PF00083 Sugar_tr [H]

EC number: NA

Molecular weight: Translated: 15403; Mature: 15272

Theoretical pI: Translated: 9.83; Mature: 9.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
5.6 %Met     (Translated Protein)
6.9 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
4.9 %Met     (Mature Protein)
6.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNSSDSDQTVQAVRLQIGRRTSMLCFGSLAAIFTVPILSALQNVSSPYAAFGLVMCALL
CCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
IVSFYTSISGILKAEMFPAQVRALGVGLSYAVANAIFGGSAEYVALSLKSIGMETAFFWY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCHHHHHHHH
VTLMAVVAFLVSLMLHRKGKGMRL
HHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
SNSSDSDQTVQAVRLQIGRRTSMLCFGSLAAIFTVPILSALQNVSSPYAAFGLVMCALL
CCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
IVSFYTSISGILKAEMFPAQVRALGVGLSYAVANAIFGGSAEYVALSLKSIGMETAFFWY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCHHHHHHHH
VTLMAVVAFLVSLMLHRKGKGMRL
HHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; 2-oxoglutarate [Periplasm] [C]

Specific reaction: Proton [Periplasm] + 2-oxoglutarate [Periplasm] = Proton [Cytoplasm] + 2-oxoglutarate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 2118499; 9205837; 9278503; 1709493; 2190187; 2053984; 8419306 [H]