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The map label for this gene is ygfA [H]

Identifier: 187731496

GI number: 187731496

Start: 3102779

End: 3103525

Strand: Direct

Name: ygfA [H]

Synonym: SbBS512_E3332

Alternate gene names: 187731496

Gene position: 3102779-3103525 (Clockwise)

Preceding gene: 187732089

Following gene: 187731995

Centisome position: 67.22

GC content: 52.61

Gene sequence:

>747_bases
ATGTGGCGCTCCGCGGTTGGTGAGCATGCTCGGTCCGTCCGAGAAGCCTTAAAACTGCGACGACACATTCACCTTGAACC
AAGGGTTCAAGGGTTACAGCCTGCGGCGGCATCTCGGAGATTCCCTTCTTATCTGGCACCAGCCATGACGCAACTACCAG
AACTCCCACTGACATTATCCCGACAAGAAATCCGCAAAATGATTCGGCAACGTCGTCGTGCGTTAACGCCGGAACAACAG
CTGGAAATGGGTCAACAAGCCGCTACCCGGATGATGACTTATCCCCCGGTGGTGATGGCGCATACGGTCGCTGTATTCCT
CTCTTTTGATGGTGAACTCGACACCCAGCCGCTAATAGAACAACTCTGGCGCGCCGGTAAGCGCGTATGTCTTCCAGTTT
TGCATCCCTTTAGTGCTGGTAATTTGCTGTTCCTGAATTACCATCCGCAAAGCGAACTGGTGATGAACAGGTTGAAAATC
CATGAGCCAAAACTGGATGTGCGTGACGTGCTACCCCTTTCCCGATTAGACGTGCTGATCACACCGCTGGTCGCCTTTGA
TGAGTACGGTCAGCGCCTGGGAATGGGCGGTGGTTTTTATGATCGGACCTTACAAAACTGGCAGCACTATAAAACGCAAC
CGGTGGGTTATGCGCATGATTGTCAGTTGGTGGAAAAACTCCCCGTTGAAGAGTGGGATATCCCTCTTCCTGCGGTGGTT
ACACCGTCGAAAGTCTGGGAGTGGTAA

Upstream 100 bases:

>100_bases
ACTTTTCGGTTTACTGTGGTAGAGTAACCGTGAAGACAAAATTTCTCTGAGATGTTCGCAAGCGGGCCAGTCCCCTGAGC
CGATATTTCATACCACAAGA

Downstream 100 bases:

>100_bases
GGGCGATACACCTGCATCGCCCTGATTGACATCGTTGATTCTTTAACCTAATTTAGTGAGTAAGGGTAAGGGAGGATTGC
TCCTCCCCTGTGACTGACTG

Product: putative ligase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 248; Mature: 248

Protein sequence:

>248_residues
MWRSAVGEHARSVREALKLRRHIHLEPRVQGLQPAAASRRFPSYLAPAMTQLPELPLTLSRQEIRKMIRQRRRALTPEQQ
LEMGQQAATRMMTYPPVVMAHTVAVFLSFDGELDTQPLIEQLWRAGKRVCLPVLHPFSAGNLLFLNYHPQSELVMNRLKI
HEPKLDVRDVLPLSRLDVLITPLVAFDEYGQRLGMGGGFYDRTLQNWQHYKTQPVGYAHDCQLVEKLPVEEWDIPLPAVV
TPSKVWEW

Sequences:

>Translated_248_residues
MWRSAVGEHARSVREALKLRRHIHLEPRVQGLQPAAASRRFPSYLAPAMTQLPELPLTLSRQEIRKMIRQRRRALTPEQQ
LEMGQQAATRMMTYPPVVMAHTVAVFLSFDGELDTQPLIEQLWRAGKRVCLPVLHPFSAGNLLFLNYHPQSELVMNRLKI
HEPKLDVRDVLPLSRLDVLITPLVAFDEYGQRLGMGGGFYDRTLQNWQHYKTQPVGYAHDCQLVEKLPVEEWDIPLPAVV
TPSKVWEW
>Mature_248_residues
MWRSAVGEHARSVREALKLRRHIHLEPRVQGLQPAAASRRFPSYLAPAMTQLPELPLTLSRQEIRKMIRQRRRALTPEQQ
LEMGQQAATRMMTYPPVVMAHTVAVFLSFDGELDTQPLIEQLWRAGKRVCLPVLHPFSAGNLLFLNYHPQSELVMNRLKI
HEPKLDVRDVLPLSRLDVLITPLVAFDEYGQRLGMGGGFYDRTLQNWQHYKTQPVGYAHDCQLVEKLPVEEWDIPLPAVV
TPSKVWEW

Specific function: Unknown

COG id: COG0212

COG function: function code H; 5-formyltetrahydrofolate cyclo-ligase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family [H]

Homologues:

Organism=Homo sapiens, GI5453746, Length=192, Percent_Identity=25, Blast_Score=76, Evalue=2e-14,
Organism=Escherichia coli, GI1789278, Length=182, Percent_Identity=98.9010989010989, Blast_Score=372, Evalue=1e-105,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002698 [H]

Pfam domain/function: PF01812 5-FTHF_cyc-lig [H]

EC number: NA

Molecular weight: Translated: 28623; Mature: 28623

Theoretical pI: Translated: 9.61; Mature: 9.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCHHHCCC
>Mature Secondary Structure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CCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]